Virus isolation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for diagnostic and research purposes.

abstract：:A new mucin antigen was detected in a mucinous cystadenoma of human ovary. An antiserum produced in rabbits against the crude cyst fluid, following appropriate absorptions, showed immunoreactivity exclusively with tumour epithelium, particularly endocervical type epithelium. The antigen responsible for the immunoreact...

journal_title：Pathology

authors： Ma J,Handley CJ,de Boer WG

更新日期：1983-10-01 00:00:00

abstract：:In 2004, the diagnosis of established human immunodeficiency virus (HIV) infection can be made with close to 100% assurity. The extraordinarily engineered performances of HIV-screening assays are unprecedented. The well-established confirmatory tests performed by well-versed laboratories using criteria that are well u...

journal_title：Pathology

authors： Dax EM,Arnott A

更新日期：2004-12-01 00:00:00

abstract：AIMS:Clinical decision making and optimal clinical trial design based on cancer genetic information will be increasingly informed by the mutational status of multiple genes. METHODS:We performed mutation screening on 22 fresh frozen gastrointestinal stromal tumours (GISTs) using a multiplexed oncogene screening panel ...

journal_title：Pathology

authors： Kang G,Lee J,Jang KT,Beadling C,Corless CL,Heinrich MC,Park JO,Kang WK,Park CK,Kim KM

更新日期：2012-08-01 00:00:00

abstract：:Recent updated models of the coagulation mechanism suggest that factor VII/thromboplastin complex is the main initiator or trigger of coagulation. Factor VII activation of factor IX is likely to be an important activation pathway. Inhibition of factor VII by tissue factor pathway inhibitor may have a regulatory role i...

journal_title：Pathology

authors： Wei DC,Wong RW,Robertson EP

更新日期：1997-05-01 00:00:00

abstract：:An epidemiological study of childhood cancer in New Zealand identified 409 children aged 0 to 14 years with malignant neoplasms newly diagnosed between 1990 and 1993 inclusive. The original microscopic material on which the diagnoses were based was reviewed in 398 cases and the neoplasms were allocated into the 12 maj...

journal_title：Pathology

authors： Becroft DM,Dockerty JD,Berkeley BB,Chan YF,Lewis ME,Skeen JE,Synek BJ,Teague LR

更新日期：1999-05-01 00:00:00

abstract：:Tru-cut biopsy post mortems were compared with the standard full autopsy at a large city mortuary. Subjects consisted of coronial cases excluding suspicious deaths, obvious trauma cases and children under the age of 14 yrs. The following comparisons were made: the ability to collect tissue from each of the organs; any...

journal_title：Pathology

authors： Foroudi F,Cheung K,Duflou J

更新日期：1995-01-01 00:00:00

abstract：:Epigenetic regulation is emerging as a critical mechanism for pancreatic ductal adenocarcinoma (PDA) development. Histone methylation is an important regulatory mechanism, altering chromatin structure and promoter accessibility and causing aberrant gene expression. NSD1 and SETD2 genes encoding two histone H3K36 methy...

journal_title：Pathology

authors： Ettel M,Zhao L,Schechter S,Shi J

更新日期：2019-06-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is currently regarded as a myeloid neoplasm, with remarkably broad clinical spectrum, ranging from isolated skin or bone lesions to a disseminated disease that can involve nearly any organ. LCH is generally regarded as a sporadic disease that occurs predominantly in the paediatric p...

journal_title：Pathology

authors： El Demellawy D,Young JL,de Nanassy J,Chernetsova E,Nasr A

更新日期：2015-06-01 00:00:00

abstract：:The mitogenic and chemotactic potency of platelet-derived growth factor (PDGF) has linked this polypeptide to the pathogenesis of several disease states including atherosclerosis and neoplasia. We have reviewed the recent literature on aspects relating to the structure, distribution and biology of PDGF and its high-af...

journal_title：Pathology

authors： Khachigian LM,Chesterman CN

更新日期：1992-10-01 00:00:00

abstract：:This review will focus on the molecular biology of lymphoproliferative disorders with emphasis on lymphomas. The spectrum of known recurrent gene rearrangements found in lymphomas will be outlined and their relevance to diagnosis and subclassification of disease will be discussed. Finally, a survey of the current tren...

journal_title：Pathology

authors： Catalano A,Iland H

更新日期：2005-12-01 00:00:00

abstract：AIMS:In our previous studies, comparative proteomics demonstrated that lactate dehydrogenase B subunit (LDH-B) is down-regulated in high grade compared to non-high grade urinary bladder urothelial carcinoma (UBUC). However, this finding has not been validated by clinical cohort investigation. Therefore, in the present ...

journal_title：Pathology

authors： Liao AC,Li CF,Shen KH,Chien LH,Huang HY,Wu TF

更新日期：2011-12-01 00:00:00

abstract：:An analysis of prognostic factors in 4000 patients with cutaneous malignant melanoma at the Sydney Melanoma Unit and the University of Alabama in Birmingham has demonstrated that the histological features of the primary melanoma become less predictive of survival the more advanced the disease becomes. Thus, whilst 4 f...

journal_title：Pathology

authors： Shaw HM,Balch CM,Soong SJ,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：:Neuroendocrine (NE) tumours are uncommon in the gynecological tract. In addition to their histological features, what defines NE carcinoma is the expression of markers such as chromogranin, synaptophysin and neural cell adhesion molecule (CD56) by immunohistochemistry (IHC). Although limited data have demonstrated tha...

journal_title：Pathology

authors： Moritz AW,Schlumbrecht MP,Nadji M,Pinto A

更新日期：2019-06-01 00:00:00

abstract：:Five cases of intraductal papillary-mucinous neoplasm (IPMN) of the pancreas are here described. This group of tumors represents a distinct clinicopathological entity with characteristic endoscopic, radiological, gross and microscopic appearances. Our five cases all showed marked dilatation of the main pancreatic duct...

journal_title：Pathology

authors： Kench JG,Eckstein RP,Smith RC

更新日期：1997-02-01 00:00:00

abstract：:Since 1967 the Royal College of Pathologists of Australasia has been providing an external quality assurance programme in microbiology. The number of participants has risen from 70 to 222, and the samples distributed for investigation have increased in quantity, now totalling 35-40 per annum, and in variety, so that m...

journal_title：Pathology

authors： Ackerman VP,Pritchard RC

更新日期：1984-07-01 00:00:00

abstract：:Human papillomavirus (HPV) is a common viral infection of squamous epithelial tissues, but its importance has only recently been recognised by the medical community. HPVs are now realised to consist of many genotypes and are associated with a diverse spectrum of clinical manifestations. Within the genital tract, some ...

journal_title：Pathology

authors： Garland SM

更新日期：2002-06-01 00:00:00

abstract：:Distinct differences in the extent and progression of the lateral and epicardial boundaries of evolving regional infarcts were demonstrated in isolated rabbit hearts. Ischemia was produced by interrupting (0-240 minutes) flow in the ventral interventricular branch of the left coronary artery, whilst the remainder of t...

journal_title：Pathology

authors： Sage MD,Gavin JB

更新日期：1985-10-01 00:00:00

abstract：:Staining for iron showed previously overlooked intra-alveolar siderophages widely distributed in the lungs of two pairs of siblings, all of whom had hospital admissions for apparent life-threatening events (ALTEs) before dying suddenly at home. A mother and babysitter were convicted of their murder and manslaughter re...

journal_title：Pathology

authors： Becroft DM,Lockett BK

更新日期：1997-02-01 00:00:00

abstract：:Cryostat sections of livers from rats treated with carbon tetrachloride (CCl4) for 12 weeks were examined by indirect immunofluorescence for reactivity with human serum containing smooth muscle antibody (SMA). Increased binding of SMA serum to hepatocytes was observed as early as the first week of CCl4 treatment and r...

journal_title：Pathology

authors： Toh BH,Cauchi MN,Muller HK

更新日期：1977-07-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) are a non-homogeneous population of plastic-adherent cells which were initially isolated from post-natal bone marrow. They have the capacity to differentiate to multiple mesodermal lineages including bone, cartilage and adipose tissue. In stringent culture conditions, MSCs can also be ...

journal_title：Pathology

authors： Larsen S,Lewis ID

更新日期：2011-10-01 00:00:00

abstract：:With the use of 2 independent techniques, circulating monomeric and oligomeric IgM were detected in the majority of 29 patients with chronic lymphocytic leukemia (CLL). In contrast it was detected only in trace quantities in a minority of healthy subjects. In the CLL group no significant correlation was observed betwe...

journal_title：Pathology

authors： Xu HJ,Roberts-Thomson PJ

更新日期：1993-01-01 00:00:00

abstract：:Tumour infiltrating lymphocytes in primary melanoma have been found to correlate with patient outcomes. A subpopulation of tumour infiltrating lymphocytes expresses the transcription factor forkhead box protein 3 (FOXP3). These are known as FOXP3+ T-regulatory cells (Tregs) and are thought to play an immune suppressiv...

journal_title：Pathology

authors： Leslie C,Bowyer SE,White A,Grieu-Iacopetta F,Trevenen M,Iacopetta B,Amanuel B,Millward M

更新日期：2015-10-01 00:00:00

abstract：:The results of semi-solid cultures of fresh biopsy material from 86 primary human melanomas are reported. Detailed histological assessments by Professor McGovern were available for 80 of the 86 melanomas, and these were compared with the growth characteristics of each specimen. Significant correlations were found betw...

journal_title：Pathology

authors： Vincent PC,Joyce RM,Croaker G,Young GA,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：:Oral cancer is a serious public health problem, with over 200,000 new cases reported annually worldwide, two-thirds of which occur in developing countries. The overall mortality rate for intra-oral cancer remains high at approximately 50%, even with modern medical services, probably due to the advanced stage of the di...

journal_title：Pathology

authors： Walker DM,Boey G,McDonald LA

更新日期：2003-10-01 00:00:00

abstract：:Plexiform leiomyomas of the uterus are incidental findings in hysterectomy specimens. Histogenetically, these rare tumors are classified as a variant of epithelioid leiomyomas. Most of the plexiform leiomyomas reported range in size from microscopically small lesions to less than 1 cm in largest diameter, and they mac...

journal_title：Pathology

authors： Nagel H,Brinck U,Lüthje D,Füzesi L

更新日期：1999-08-01 00:00:00

abstract：:Inflammatory pseudotumor (IP) is an uncommon tumor-like lesion of unknown etiology. Two cases of IP of the epididymis were identified in our hospital file. Having read a recent report on finding Epstein-Barr virus (EBV) in some cases of IP in lymph node, spleen and liver, the two cases of epididymal IP were tested for...

journal_title：Pathology

authors： Chan KW,Chan KL,Lam KY

更新日期：1997-02-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is composed of two distinct pathological entities, nodular lymphocyte predominant HL and classic HL, the latter with four subtypes. In contrast with most other human lymphomas, in which the neoplastic cells are a major population of the tumour constituents, the neoplastic 'Hodgkin (H) and Reed-St...

journal_title：Pathology

authors： Piris MA,Medeiros LJ,Chang KC

更新日期：2020-01-01 00:00:00

abstract：:We report a rare case of bilateral primary seminal vesicle carcinoma in a 73 yr old Australian man. To our knowledge this case report is the 48th histologically confirmed case of primary seminal vesicle neoplasia and only the fourth reported case of primary bilateral seminal vesicle carcinoma. Macroscopically the tumo...

journal_title：Pathology

authors： Ormsby AH,Haskell R,Ruthven SE,Mylne GE

更新日期：1996-05-01 00:00:00

abstract：:Exfoliative, abrasive and aspiration cytology were increasingly relied upon for tissue diagnosis of tumours. The established histological stains for the differentiation of mucin and non-mucin-secreting tumours are not ideal for alcohol-fixed cytology smears and a more reliable cytological technique for the preservatio...

journal_title：Pathology

authors： Nathan NA,van Deth AG

更新日期：1983-07-01 00:00:00

abstract：:Appropriate investigation of a patient with suspected von Willebrand's disease (VWD) involves a clinical assessment of the patient followed by laboratory testing. A variety of laboratory assays may be performed, not necessarily restricted to an assessment of von Willebrand factor (VWF). Due to the limitations of each ...

journal_title：Pathology

authors： Favaloro EJ,Koutts J

更新日期：1997-11-01 00:00:00