Detection of BRAF V600E mutation by pyrosequencing.

abstract：:The aims of this study were to investigate the immunohistochemical expression and potential prognostic significance of putative cancer stems cell markers ALDH1, EZH2 and SOX2 in prostate cancer.A total of 142 consecutive radical prostatectomies submitted to one laboratory with a diagnosis of prostatic adenocarcinoma b...

journal_title：Pathology

authors： Matsika A,Srinivasan B,Day C,Mader SA,Kiernan DM,Broomfield A,Fu J,Hooper JD,Kench JG,Samaratunga H

更新日期：2015-12-01 00:00:00

abstract：:Associations between histologically defined proliferative, but benign, epithelial disorders of the breast and risk factors for breast carcinoma were examined in 568 patients whose breast biopsies were submitted consecutively to the laboratory. Some disorders were associated with multiparity. Blunt duct adenosis was as...

journal_title：Pathology

authors： Cook MG,Rohan TE

更新日期：1991-10-01 00:00:00

abstract：:A calcified nodule on the liver of a 62-year-old man from North Carolina, USA, contained a degenerated nymph of Linguatula serrata. The nodule was incidentally discovered at laparotomy for malignant lymphoma and cholelithiasis. The cuticle was all that remained of the parasite, but sclerotized openings and large spine...

journal_title：Pathology

authors： Baird JK,Kassebaum LJ,Ludwig GK

更新日期：1988-04-01 00:00:00

abstract：:Various tumour markers have been evaluated in malignant pleural effusions, but not CD66c. This study evaluated the diagnostic ability of CD66c in lung adenocarcinoma-associated malignant pleural effusions (LA-MPEs) and compared it with other known tumour markers. Forty-seven cases of LA-MPE and 52 cases of benign pleu...

journal_title：Pathology

authors： Son SM,Han HS,An JY,Choe KH,Lee KM,Lee KH,Kim SS,Lee YM,Lee HC,Song HG,Lee OJ

更新日期：2015-02-01 00:00:00

abstract：:The morphology of livers of Wistar rats treated with beta-carotene (BC), vitamin A (VA, retinol acetate) or corn oil (CO, controls) and submitted to the resistant hepatocyte model of carcinogenesis was studied. Preneoplastic lesions (PNL) were smaller and less numerous in the BC group. The latter group also presented ...

journal_title：Pathology

authors： Dagli ML,Guerra JL,Sinhorini IL,Wu TS,Rizzi MB,Penteado MV,Moreno FS

更新日期：1998-08-01 00:00:00

abstract：:Human glomerular basement membrane (GBM) emulsified in Freund's complete adjuvant was injected into 16 Holtzman rats. Eleven (69%) of them subsequently developed glomerulonephritis. This disease was characterized by glomerular changes which included focal lobular hypercellularity due to localized hyperplasia of intrac...

journal_title：Pathology

authors： McCausland IP,Herdson PB,Gavin JB

更新日期：1976-04-01 00:00:00

abstract：:A new three-tiered Pattern Classification system for usual-type endocervical adenocarcinomas (U-EACs) recommends using tumour invasive patterns rather than depth of invasion (DOI) and horizontal spread to categorise tumours. Tumours categorised by Pattern Classification are associated with lymph node (LN) metastasis a...

journal_title：Pathology

authors： Xu H,Pan H,Wang Y,Zhang J

更新日期：2019-10-01 00:00:00

abstract：:Post-transplant lymphoproliferative disorders (PTLD) are a consequence of the immunosuppressive therapy following organ transplant. We describe a patient who developed PTLD seven years after liver transplant and while receiving cyclosporine and prednisone. Magnetic resonance imaging demonstrated a paraspinal mass exte...

journal_title：Pathology

authors： Grosso LE,Bee CS

更新日期：1998-11-01 00:00:00

abstract：AIM:Considering the fact that histology and its grading systems are accepted gold standards in diagnosis of diverse clinical disorders, assessing the accuracy and reliability of this method of diagnosis is of utmost importance. Thus, this study was performed to measure the agreement values between four independent hist...

journal_title：Pathology

authors： Talebkhan Y,Mohammadi M,Rakhshani N,Abdirad A,Fayaz Moughadam K,Fereidooni F

更新日期：2009-01-01 00:00:00

abstract：AIMS:In our previous studies, comparative proteomics demonstrated that lactate dehydrogenase B subunit (LDH-B) is down-regulated in high grade compared to non-high grade urinary bladder urothelial carcinoma (UBUC). However, this finding has not been validated by clinical cohort investigation. Therefore, in the present ...

journal_title：Pathology

authors： Liao AC,Li CF,Shen KH,Chien LH,Huang HY,Wu TF

更新日期：2011-12-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is currently regarded as a myeloid neoplasm, with remarkably broad clinical spectrum, ranging from isolated skin or bone lesions to a disseminated disease that can involve nearly any organ. LCH is generally regarded as a sporadic disease that occurs predominantly in the paediatric p...

journal_title：Pathology

authors： El Demellawy D,Young JL,de Nanassy J,Chernetsova E,Nasr A

更新日期：2015-06-01 00:00:00

abstract：:We present the clinicopathological features of eight cases of large cell undifferentiated bladder carcinoma not otherwise specified (LCUBC). LCUBC was characterised by sheets of large polygonal or round cells with moderate to abundant cytoplasm and distinct cell borders. The LCUBC component varied from 90 to 100% of t...

journal_title：Pathology

authors： Lopez-Beltran A,Cheng L,Comperat E,Rouprêt M,Blanca A,Menendez CL,Montironi R

更新日期：2010-06-01 00:00:00

abstract：:Penile metastases from prostate cancer are rare and are usually a manifestation of wide-spread cancer dissemination. Isolated urethral metastases form a small fraction of these cases, have a longer survival rate and may represent spread by implantation following instrumentation. We report a case of prostatic carcinoma...

journal_title：Pathology

authors： Taylor GB,McNeal JE,Cohen RJ

更新日期：1998-05-01 00:00:00

abstract：:The dense fine speckled (DFS) pattern is an antinuclear antibody (ANA) pattern that has recently become of interest. This particular pattern has not been associated with systemic autoimmune rheumatic disorders (SARD) but has been associated with other inflammatory conditions such as interstitial nephritis, autoimmune ...

journal_title：Pathology

authors： Broadfoot A,Sivertsen T,Baumgart K

更新日期：2016-04-01 00:00:00

abstract：:The clinical and autopsy findings in a premature baby who died of acute renal failure after therapy with gentamicin (5 mg/kg/day) and penicillin are presented. The serum gentamicin concentration had reached toxic levels when anuria developed. Numerous periodic acid Schiff (PAS) positive, diastase resistant cytoplasmic...

journal_title：Pathology

authors： Chan KW,Ng WL

更新日期：1985-07-01 00:00:00

abstract：:The clinical course and biopsy findings of twenty-one patients with IgA nephropathy, followed up for a mean period of 37.4 mth (range 24-54 mth) after diagnosis, were reviewed retrospectively to determine whether the clinical presentations, the laboratory findings or histopathologic changes have prognostic implication...

journal_title：Pathology

authors： Ng WL,Loke SL,Yeung CK,Kwan S,Chan KW,Chan MK

更新日期：1986-01-01 00:00:00

abstract：:A study of 103 fetal adrenals obtained from stillborn fetuses and those dying in the neonatal period was performed to assess the significance of definitive cortex cystic change, compact cell change and lipid patterns, and their relationship to other pathological processes. The findings confirm that these changes are m...

journal_title：Pathology

authors： Delprado WJ,Baird PJ

更新日期：1984-07-01 00:00:00

abstract：AIM:We investigated the role of renal sympathetic innervation in the deterioration of renal haemodynamic and excretory functions during the early post-ischaemic phase of renal ischaemia/reperfusion injury. METHODS:Anaesthetised male Sprague-Dawley rats were subjected to unilateral renal ischaemia by clamping the left ...

journal_title：Pathology

authors： Salman IM,Ameer OZ,Sattar MA,Abdullah NA,Yam MF,Najim HS,Khan AH,Johns EJ

更新日期：2010-04-01 00:00:00

abstract：:The lupus anticoagulant (LA) phenomenon created world-wide interest recently. Various tests have been devised to identify LA in plasma, but none of these methods have been universally accepted. In this study 16 cases labelled LA positive by a prior kaolin clotting time (KCT) test were reassessed by four other methods,...

journal_title：Pathology

authors： Stark RA,Gordon S

更新日期：1990-04-01 00:00:00

abstract：:Weanling rats were given a low Ca (0.003%)/high P (0.64%) diet with and without vitamin D for periods up to 6 weeks. An ultrastructural examination of selected areas of the proximal tibial metaphysis was carried out to study osteoclasts and their relation to calcified and uncalcified bone tissue. Osteoclasts were seen...

journal_title：Pathology

authors： Feik SA,Storey E

更新日期：1979-10-01 00:00:00

abstract：:Age-specific paediatric reference intervals are used in interpretation of laboratory results. However, interpretation may be problematic when a child just crosses an age bracket and the difference between the original and the subsequent age-specific reference interval is large. Moreover, details about the physiologica...

journal_title：Pathology

authors： Loh TP,Antoniou G,Baghurst P,Metz MP

更新日期：2014-06-01 00:00:00

abstract：AIMS:Nuclear factor-kappa B (NF-kappaB) activation has been recognised as an important mechanism in the development of cancers. However, expression status of NF-kappaB-related proteins in oesophageal squamous cell carcinoma (ESCC) tissues is largely unknown. In this study, we analysed expressions of NF-kappaB members (...

journal_title：Pathology

authors： Kang MR,Kim MS,Kim SS,Ahn CH,Yoo NJ,Lee SH

更新日期：2009-01-01 00:00:00

abstract：:Tumor cell-platelet interactions have been shown to be involved in the process of metastasis. This study characterizes the aggregation of washed platelets induced by the human uterine carcinosarcoma Colo 526. Ultrastructural studies revealed a two-stage process in which the earliest events were the adhesion and degran...

journal_title：Pathology

authors： Bradley CJ,Dauer RJ,Thurlow PJ,Connellan JM

更新日期：1997-05-01 00:00:00

abstract：:This report describes the case of a 63 yr old male with an enlarging lesion on the left cheek. Excision biopsy showed a squamous cell carcinoma arising from an eccrine hidrocystoma. The eccrine hidrocystoma showed foci of squamous metaplasia and the sequence of squamous metaplasia complicated by squamous carcinoma is ...

journal_title：Pathology

authors： Theocharous C,Jaworski RC

更新日期：1993-04-01 00:00:00

abstract：:Deregulation of the receptors of TNF-related apoptosis inducing ligand (TRAIL) has been reported in various cancers. In an effort to define the role of these receptors we profiled their expression in gallbladder cancer (GBC) and explored their clinical significance. Expression of TRAIL receptors' mRNA in GBC was analy...

journal_title：Pathology

authors： Singh D,Prasad CB,Biswas D,Tewari M,Kar AG,Ansari MA,Singh S,Narayan G

更新日期：2020-04-01 00:00:00

abstract：:Tissue from the epiphyseal plate of a patient with Morquio type A syndrome (mucopolysaccharidosis type IVA) was studied by undecalcified histological and electron microscopical techniques. Cartilage cells in the plate were vacuolated to a variable degree. The orderly proliferating structure of the epiphyseal plate was...

journal_title：Pathology

authors： McClure J,Smith PS,Sorby-Adams G,Hopwood J

更新日期：1986-04-01 00:00:00

abstract：:In order to determine whether routine culturing for Clostridium difficile was warranted or whether culturing a selected group of patients was adequate, we conducted a prospective trial of culturing all stool specimens for C. difficile. A total of 408 specimens from 297 patients was studied. Two hundred and eighteen st...

journal_title：Pathology

authors： Bowman RA,Riley TV

更新日期：1984-07-01 00:00:00

abstract：AIM:The purpose of this study was to elucidate the clonality of fibrous dysplasia based on X-chromosome inactivation mosaicism and polymorphism in female somatic cells at the phosphoglycerate kinase (PGK) and androgen receptor (AR) loci using microdissection technology. MATERIALS AND METHODS:Nine patients with fibrous...

journal_title：Pathology

authors： Gong L,Zhang W,Su Q

更新日期：2008-06-01 00:00:00

abstract：:Granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. Once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous m...

journal_title：Pathology

authors： Johnstone KJ,Robson J,Cherian SG,Wan Sai Cheong J,Kerr K,Bligh JF

更新日期：2017-06-01 00:00:00

abstract：:We present the clinical and postmortem findings in seven adults (four females and three males), who died with dissection of the coronary arteries. The median age was 56 years. Five of the coronary artery dissections (CADs) were spontaneous and two followed trauma: one a motor vehicle accident, the other occurred durin...

journal_title：Pathology

authors： Mulvany NJ,Ranson DL,Pilbeam MC

更新日期：2001-08-01 00:00:00