Intraductal carcinoma of the prostate metastatic to the penile urethra: a rare demonstration of two morphologic patterns of tumor growth.

abstract：:This report describes the diagnostic problem caused by an atypical immunoglobulin-bound creatine kinase isoenzyme in a patient who had a myocardial infarction. In the presence of this atypical isoenzyme, creatine kinase isoenzyme electrophoresis was of no help in determining whether myocardial infarction had occurred....

journal_title：Pathology

authors： Campbell BG,Jones BW,Burnet J

更新日期：1990-01-01 00:00:00

abstract：:Decreased neutrophil alkaline phosphatase (NAP) synthesis is a classical feature of Philadelphia (Ph) positive chronic phase chronic myeloid leukemia (CML). Whether this aberration is an integral leukemic property of the cell or results from mediation by other factors is unclear. During alpha-interferon (alpha-IFN) ba...

journal_title：Pathology

authors： Taylor DL,Kerwick AM,Elliott SL,Rodwell RL,Wright SJ,Marlton PV,Veleba AR,Taylor KM

更新日期：1993-10-01 00:00:00

abstract：:A strain of Serratia marcescens, isolated from the blood cultures of a patient receiving antibiotics, exhibited 3 unstable properties. These properties were resistance to aminoglycosides, colony size and pigment production. While resistance to aminoglycosides was linked to colony size, pigment production appeared inde...

journal_title：Pathology

authors： Ruhen RW,Wetherall FM

更新日期：1983-01-01 00:00:00

abstract：:Colonic mucosal biopsies from patients with melanosis coli were examined by electron microscopy. They showed apoptosis of colonic surface epithelial cells and phagocytosis of resulting apoptotic bodies by intraepithelial macrophages. The latter migrated to the lamina propria where intracellular degradation of the apop...

journal_title：Pathology

authors： Walker NI,Smith MM,Smithers BM

更新日期：1993-04-01 00:00:00

abstract：:Hodgkin lymphoma (HL) is composed of two distinct pathological entities, nodular lymphocyte predominant HL and classic HL, the latter with four subtypes. In contrast with most other human lymphomas, in which the neoplastic cells are a major population of the tumour constituents, the neoplastic 'Hodgkin (H) and Reed-St...

journal_title：Pathology

authors： Piris MA,Medeiros LJ,Chang KC

更新日期：2020-01-01 00:00:00

abstract：:An unusual case of gliomatosis cerebri in a 37 yr-old man is reported. He presented with a variable clinical picture. Mental changes, brain stem signs, cerebellar signs and rise in intracranial pressure were the constant findings. The postmortem findings are described and the available literature is reviewed. ...

journal_title：Pathology

authors： Balakrishnan V,Hornabrook RW,Alexander WS

更新日期：1985-01-01 00:00:00

abstract：:A case is described of a mediastinal soft tissue sarcoma, in a 76-year-old man, characterized microscopically by the intimate combined features of liposarcoma and leiomyosarcoma. The lipomatous component consisted of well differentiated liposarcoma with myxoid areas. The smooth muscle component was characterized by fa...

journal_title：Pathology

authors： Gómez-Román JJ,Val-Bernal JF

更新日期：1997-11-01 00:00:00

abstract：:Malignant gastrointestinal neuroectodermal tumour (GNET) is a recently characterised rare and aggressive tumour that typically arises in association with the small intestine of adults. We present a novel case of this entity and expand the spectrum of its reported morphological features. The patient was a 5-year-old fe...

journal_title：Pathology

authors： Allanson BM,Weber MA,Jackett LA,Chan C,Lau L,Ziegler DS,Warby M,Mayoh C,Cowley MJ,Tucker KM,Long GV,Maher A,Anazodo A,Scolyer RA

更新日期：2018-10-01 00:00:00

abstract：AIMS:p73, a homologue of p53, is known as a negative regulator of tumour progression. However, delta Np73, an isoform of p73 lacking the NH2-terminal transactivation domain plays an oncogenic role by interfering with the activity of p53 and TA (full-length transactivating isoforms) p73. In this study, we investigated t...

journal_title：Pathology

authors： Ito Y,Uramoto H,Funa K,Yoshida H,Jikuzono T,Asahi S,Higashiyama T,Tomoda C,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Kuma K,Miyauchi A

更新日期：2006-06-01 00:00:00

abstract：:We evaluated an immunoradiometric assay for serum TSH (IRMA-TSH) and compared it with established indices of thyroid function in 208 patients with either frank thyroid disease, conditions of abnormal thyroxine protein binding, or conditions which are known to produce discordant thyroid results, viz. pregnancy or estro...

journal_title：Pathology

authors： McLellan GH,Riley WJ,Summers MB,Sudholz P,Hickman PE

更新日期：1987-07-01 00:00:00

abstract：:The prevalence of complement-fixing (CF) antibody against the AG-4 early antigen of herpes simplex virus (HSV) type 2 (HSV-2) was determined in patients with culture confirmed HSV-2 genital herpes and control groups using a commercial HSV-2 early antigen (Simplex-2; Gene Link Australia Ltd). Eighty seven per cent of 3...

journal_title：Pathology

authors： Field PR,Ho DW,Cunningham AL

更新日期：1992-10-01 00:00:00

abstract：AIMS:BRAF mutation has been shown in a large meta-analysis to be an independent prognostic marker for papillary thyroid carcinoma (PTC) with poorer survival and higher recurrence rates. METHODS:We studied prevalence of BRAF mutation in 77 patients with PTC from an Australian cohort using competitive polymerase chain r...

journal_title：Pathology

authors： McKelvie PA,Chan F,Yu Y,Waring P,Gresshoff I,Farrell S,Williams RA

更新日期：2013-12-01 00:00:00

abstract：:This report describes the case of a 63 yr old male with an enlarging lesion on the left cheek. Excision biopsy showed a squamous cell carcinoma arising from an eccrine hidrocystoma. The eccrine hidrocystoma showed foci of squamous metaplasia and the sequence of squamous metaplasia complicated by squamous carcinoma is ...

journal_title：Pathology

authors： Theocharous C,Jaworski RC

更新日期：1993-04-01 00:00:00

abstract：AIM:Hepcidin, a recently identified peptide, acts as a central regulator of iron metabolism. It is regarded as a factor regulating the uptake of dietary iron and its mobilisation from macrophages and hepatic stores. It is considered as a mediator of anaemia of inflammation. The aim of this study was to assess whether s...

journal_title：Pathology

authors： Jayaranee S,Sthaneshwar P,Sokkalingam S

更新日期：2009-02-01 00:00:00

abstract：AIMS:Activation of nuclear factor-kappa B (NF-kappaB) signalling is considered a crucial mechanism in the development of cancers. Caspase-associated recruitment domain 6 (CARD6) is a protein that activates NF-kappaB signalling evoked by RIP1, RIP2, Bcl-10 and MEKK. In this study, we analysed tissue expression of CARD6 ...

journal_title：Pathology

authors： Kim SS,Ahn CH,Kang MR,Kim YR,Kim HS,Yoo NJ,Lee SH

更新日期：2010-01-01 00:00:00

abstract：:Tissue from the epiphyseal plate of a patient with Morquio type A syndrome (mucopolysaccharidosis type IVA) was studied by undecalcified histological and electron microscopical techniques. Cartilage cells in the plate were vacuolated to a variable degree. The orderly proliferating structure of the epiphyseal plate was...

journal_title：Pathology

authors： McClure J,Smith PS,Sorby-Adams G,Hopwood J

更新日期：1986-04-01 00:00:00

abstract：AIM:Gasdermin-like (GSDML) is a novel member of the cancer associated gasdermin-domain containing (GSDMDC) protein family. The GSDMDC family has been linked to cancer development and progression, and this is the first study analysing the expression and intracellular localisation of GSDML. METHODS:GSDML gene transcript...

journal_title：Pathology

authors： Carl-McGrath S,Schneider-Stock R,Ebert M,Röcken C

更新日期：2008-01-01 00:00:00

abstract：:Solitary fibrous tumour (SFT) is well-described in the urinary tract, but malignant examples are rare. We studied our experience with high grade malignant SFT of the prostate to address the degree of histological and immunophenotypical overlap with sarcomatoid carcinoma and prostatic stromal sarcoma. Four cases were i...

journal_title：Pathology

authors： Bakhshwin A,Berry RS,Cox RM,Li R,Reynolds JP,Rubin BP,McKenney JK

更新日期：2020-10-01 00:00:00

abstract：:The clinical and laboratory features of a patient with a recently recognized new variant of von Willebrand's disease are presented. The importance of this variant is that it is associated with a clinically significant bleeding diathesis but with a normal skin bleeding time, PTTK, factor VIIIc and platelet aggregation ...

journal_title：Pathology

authors： Wylie B,Gibson J,Uhr E,Kronenberg H

更新日期：1988-01-01 00:00:00

abstract：AIM:Lignocaine, a topical anaesthetic agent, is generally used in variable concentrations usually between 2% and 4% on the vocal cords prior to flexible bronchoscopy and bronchoalveolar lavage (BAL) procedures. The aim of this study was to investigate whether 2% or 1% lignocaine significantly inhibits the growth of org...

journal_title：Pathology

authors： Chandan SS,Faoagali J,Wainwright CE

更新日期：2005-08-01 00:00:00

abstract：:Eight histologically-confirmed cases of clear cell sarcoma of the kidney (CCSK) were studied for possible mutations in the p53 tumor suppressor gene by the immunohistochemical demonstration of mutant p53 proteins using a monoclonal (DO7: Dako) and a polyclonal (AB565: Chemicon) antibody to p53 protein. All cases exhib...

journal_title：Pathology

authors： Cheah PL,Looi LM

更新日期：1996-08-01 00:00:00

abstract：:The results of cytological examination of 1280 transrectal fine needle aspiration biopsies of the prostate from 1122 patients over a period of 10 years are given. The technique was used for the diagnosis of prostatic carcinoma. The microscopic appearances including classification according to differentiation are descr...

journal_title：Pathology

authors： Lin BP,Davies WE,Harmata PA

更新日期：1979-10-01 00:00:00

abstract：:Tonsil swabs were collected from 248 children (1 through 10 yr) who presented with acute tonsillitis. A beta-hemolytic streptococcus was grown from 129 (53%) of 244 cases and as the sole pathogen from 83 (47%) of 178 cases. Beta-Hemolytic streptococci were especially common over the age of 6 yr (68% of children) relat...

journal_title：Pathology

authors： Douglas RM,Miles H,Hansman D,Fadejevs A,Moore B,Bollen MD

更新日期：1984-01-01 00:00:00

abstract：:Four hundred and ten thyroid nodules, 127 breast lumps and 43 lymph nodes were sampled and analyzed to compare the classical aspiration (ASP) technique with the non aspiration needle jab (NASP) technique. The adequacy of cellularity, significant blood staining and the discomfort felt by the patient were assessed and s...

journal_title：Pathology

authors： Kumarasinghe MP,Sheriffdeen AH

更新日期：1995-10-01 00:00:00

abstract：:An analysis of prognostic factors in 4000 patients with cutaneous malignant melanoma at the Sydney Melanoma Unit and the University of Alabama in Birmingham has demonstrated that the histological features of the primary melanoma become less predictive of survival the more advanced the disease becomes. Thus, whilst 4 f...

journal_title：Pathology

authors： Shaw HM,Balch CM,Soong SJ,Milton GW,McCarthy WH

更新日期：1985-04-01 00:00:00

abstract：:An epidemiological study of childhood cancer in New Zealand identified 409 children aged 0 to 14 years with malignant neoplasms newly diagnosed between 1990 and 1993 inclusive. The original microscopic material on which the diagnoses were based was reviewed in 398 cases and the neoplasms were allocated into the 12 maj...

journal_title：Pathology

authors： Becroft DM,Dockerty JD,Berkeley BB,Chan YF,Lewis ME,Skeen JE,Synek BJ,Teague LR

更新日期：1999-05-01 00:00:00

abstract：:Weanling rats were given a low Ca (0.003%)/high P (0.64%) diet with and without vitamin D for periods up to 6 weeks. An ultrastructural examination of selected areas of the proximal tibial metaphysis was carried out to study osteoclasts and their relation to calcified and uncalcified bone tissue. Osteoclasts were seen...

journal_title：Pathology

authors： Feik SA,Storey E

更新日期：1979-10-01 00:00:00

abstract：:A cerebral neuroblastoma was studied by light microscopy, tissue culture and electron microscopy. Synapse-like structures were found within tumour cells. This supports the neuroectodermal origin of this neoplasm. ...

journal_title：Pathology

authors： Ojeda VJ,Jacobsen PF,Papadimitriou JM

更新日期：1980-04-01 00:00:00

abstract：:Bordetella pertussis, the aetiological agent of whooping cough is routinely diagnosed by polymerase chain reaction (PCR) directed at IS481, an insertion sequence target also found in Bordetella holmesii. Recent reports have suggested that B. holmesii infections can be misdiagnosed as pertussis, which can have a signif...

journal_title：Pathology

authors： Fong W,Timms V,Holmes N,Sintchenko V

更新日期：2018-04-01 00:00:00

abstract：:Gene targeting ('knock-out') technology is now widely used in the basic science of all disciplines of pathology and particularly auto-immune and inflammatory disease. Gene targeting is the wilful introduction of precise mutations into the genome of an animal, usually a mouse, affecting the function of a single gene or...

journal_title：Pathology

authors： Riminton DS

更新日期：2002-04-01 00:00:00