Comparison of four laboratory tests for lupus anticoagulant.

Abstract:

:The lupus anticoagulant (LA) phenomenon created world-wide interest recently. Various tests have been devised to identify LA in plasma, but none of these methods have been universally accepted. In this study 16 cases labelled LA positive by a prior kaolin clotting time (KCT) test were reassessed by four other methods, namely delta KCT (delta kaolin clotting time), APTT (activated partial thromboplastin time), PNP (platelet neutralization procedure), and DRVVT (dilute Russell viper venom time). Anti-cardiolipin antibodies (ACL) were also looked for. In our hands the delta KCT proved to be a simple, sensitive test, not influenced by oral anticoagulant therapy, and we recommend it as a screening test. Where the presence of LA is strongly suspected on clinical and other groups, more than one method may be necessary for the diagnosis.

journal_name

Pathology

journal_title

Pathology

authors

Stark RA,Gordon S

doi

10.3109/00313029009063794

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

122-3

issue

2

eissn

0031-3025

issn

1465-3931

journal_volume

22

pub_type

杂志文章
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    更新日期:1988-01-01 00:00:00

  • Large cell undifferentiated carcinoma of the urinary bladder.

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    pub_type: 杂志文章

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