当前位置： SCI文献检索 > Cell Host & Microbe期刊下所有文献 > Finding Leishmania: a deadly game of hide-and-seek.

Finding Leishmania: a deadly game of hide-and-seek.

Abstract：

:Leishmaniasis is a chronic infection in which intracellular parasites avoid destruction by the immune system. Using intravital imaging, Filipe-Santos et al. (2009) demonstrate that some parasitized dendritic cells receive much less attention than others during their choreographed dance with T cells, suggesting that these "wallflowers" could allow for parasite survival.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Scott P

doi

10.1016/j.chom.2009.07.002

subject

Has Abstract

pub_date

2009-07-23 00:00:00

pages

3-4

issue

1

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(09)00223-6

journal_volume

6

pub_type

评论,杂志文章,评审

相关文献

Cell Host & Microbe文献大全
  • Autophagy: Suicide Prevention Hotline for the Gut Epithelium.

    abstract：:Autophagy is genetically associated with inflammatory bowel disease (IBD); however, its role remains unclear in disease pathogenesis. Three recent studies reveal a novel cytoprotective role of autophagy during viral, bacterial, and protozoan-triggered IBD (Burger et al., 2018; Matsuzawa-Ishimoto et al., 2017; Pott et ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2018.01.015

    authors： Grizotte-Lake M,Vaishnava S

    更新日期：2018-02-14 00:00:00

  • Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level.

    abstract：:The human microbiome encodes extensive metabolic capabilities, but our understanding of the mechanisms linking gut microbes to human metabolism remains limited. Here, we focus on the conversion of cholesterol to the poorly absorbed sterol coprostanol by the gut microbiota to develop a framework for the identification ...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.05.013

    authors： Kenny DJ,Plichta DR,Shungin D,Koppel N,Hall AB,Fu B,Vasan RS,Shaw SY,Vlamakis H,Balskus EP,Xavier RJ

    更新日期：2020-08-12 00:00:00

  • Longitudinal Human Antibody Repertoire against Complete Viral Proteome from Ebola Virus Survivor Reveals Protective Sites for Vaccine Design.

    abstract：:Evolution of antibody repertoire against the Ebola virus (EBOV) proteome was characterized in an acutely infected patient receiving supportive care alone to elucidate virus-host interactions over time. Differential kinetics are observed for IgM-IgG-IgA epitope diversity, antibody binding, and affinity maturation to EB...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.01.001

    authors： Khurana S,Ravichandran S,Hahn M,Coyle EM,Stonier SW,Zak SE,Kindrachuk J,Davey RT Jr,Dye JM,Chertow DS

    更新日期：2020-02-12 00:00:00

  • Making It Stick: A Compelling Case for Precision Microbiome Reconstitution.

    abstract：:Modification of the intestinal microbiome is an emerging target to improve health and prevent or treat a number of diseases. In this issue of Cell Host & Microbe, Maldonado-Gómez et al. (2016) uncover the basic principles that govern the successful establishment and persistence of an exogenously introduced gut bacteri...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2016.09.012

    authors： Berry D

    更新日期：2016-10-12 00:00:00

  • Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection.

    abstract：:The clinically silent Plasmodium liver stage is an obligatory step in the establishment of malaria infection and disease. We report here that expression of heme oxygenase-1 (HO-1, encoded by Hmox1) is upregulated in the liver following infection by Plasmodium berghei and Plasmodium yoelii sporozoites. HO-1 overexpress...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.04.003

    authors： Epiphanio S,Mikolajczak SA,Gonçalves LA,Pamplona A,Portugal S,Albuquerque S,Goldberg M,Rebelo S,Anderson DG,Akinc A,Vornlocher HP,Kappe SH,Soares MP,Mota MM

    更新日期：2008-05-15 00:00:00

  • Mechanisms underlying robustness and tunability in a plant immune signaling network.

    abstract：:The plant immune signaling network needs to be robust against attack from fast-evolving pathogens and tunable to optimize immune responses. We investigated the basis of robustness and tunability in the signaling network controlling pattern-triggered immunity (PTI) in Arabidopsis. A dynamic network model containing fou...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2013.12.002

    authors： Kim Y,Tsuda K,Igarashi D,Hillmer RA,Sakakibara H,Myers CL,Katagiri F

    更新日期：2014-01-15 00:00:00

  • Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

    abstract：:Bone marrow transplantation (BMT) offers curative potential for patients with high-risk hematologic malignancies, but the post-transplantation period is characterized by profound immunodeficiency. Recent studies indicate that the intestinal microbiota not only regulates mucosal immunity, but can also contribute to sys...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2018.03.002

    authors： Staffas A,Burgos da Silva M,Slingerland AE,Lazrak A,Bare CJ,Holman CD,Docampo MD,Shono Y,Durham B,Pickard AJ,Cross JR,Stein-Thoeringer C,Velardi E,Tsai JJ,Jahn L,Jay H,Lieberman S,Smith OM,Pamer EG,Peled JU,Cohen

    更新日期：2018-04-11 00:00:00

  • Bacteria Tell Us How to Protect Our Intestine.

    abstract：:The inner colon mucus layer capacity to separate bacteria from the epithelium is dependent on bacterial colonizers signaling to the host epithelium. In this issue of Cell Host & Microbe, Wlodarska et al. (2017) demonstrate that the mucin-utilizing Peptostreptococcus russellii protects the host from inflammatory diseas...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2017.06.011

    authors： Birchenough G,Hansson GC

    更新日期：2017-07-12 00:00:00

  • HIV Latency: Stochastic across Multiple Scales.

    abstract：:Proviral latency is a major barrier to a cure for HIV. In this issue of Cell Host & Microbe, Hataye et al. (2019) show that reactivation of HIV latency is a non-deterministic, highly stochastic (i.e., noisy) process and propose that stochastic transitions to exponential viral expansion require a critical threshold of ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2019.11.010

    authors： Hansen MMK,Martin B,Weinberger LS

    更新日期：2019-12-11 00:00:00

  • A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent.

    abstract：:The Lyme disease agent Borrelia burgdorferi is primarily transmitted to vertebrates by Ixodes ticks. The classical and alternative complement pathways are important in Borrelia eradication by the vertebrate host. We recently identified a tick salivary protein, designated P8, which reduced complement-mediated killing o...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2011.06.010

    authors： Schuijt TJ,Coumou J,Narasimhan S,Dai J,Deponte K,Wouters D,Brouwer M,Oei A,Roelofs JJ,van Dam AP,van der Poll T,Van't Veer C,Hovius JW,Fikrig E

    更新日期：2011-08-18 00:00:00

  • A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion.

    abstract：:Alphaviruses infect cells via a low-pH-triggered membrane fusion reaction mediated by the class II virus fusion protein E1, an elongated molecule with three extramembrane domains (DI-III). E1 drives fusion by inserting its fusion peptide loop into the target membrane and refolding to a hairpin-like trimer in which DII...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.10.012

    authors： Sánchez-San Martín C,Sosa H,Kielian M

    更新日期：2008-12-11 00:00:00

  • Homeostasis in infected epithelia: stem cells take the lead.

    abstract：:To maintain tissue homeostasis and avoid disease, epithelial cells damaged by pathogens need to be readily replenished, and this is mainly achieved by the activation of stem cells. In this Short Review, we discuss recent developments in the exciting field of host epithelia-pathogen interaction in Drosophila as well as...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2009.10.001

    authors： Pitsouli C,Apidianakis Y,Perrimon N

    更新日期：2009-10-22 00:00:00

  • Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis.

    abstract：:Disruption of homeostasis between the host immune system and the intestinal microbiota leads to inflammatory bowel disease (IBD). Whether IBD is instigated by individual species or disruptions of entire microbial communities remains controversial. We characterized the fecal microbial communities in the recently descri...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2010.08.004

    authors： Garrett WS,Gallini CA,Yatsunenko T,Michaud M,DuBois A,Delaney ML,Punit S,Karlsson M,Bry L,Glickman JN,Gordon JI,Onderdonk AB,Glimcher LH

    更新日期：2010-09-16 00:00:00

  • KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses.

    abstract：:Human type A Enteroviruses (EV-As) cause diseases ranging from hand-foot-and-mouth disease to poliomyelitis-like disease. Although cellular receptors are identified for some EV-As, they remain elusive for the majority of EV-As. We identify the cell surface molecule KREMEN1 as an entry receptor for coxsackievirus A10 (...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2018.03.019

    authors： Staring J,van den Hengel LG,Raaben M,Blomen VA,Carette JE,Brummelkamp TR

    更新日期：2018-05-09 00:00:00

  • Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling.

    abstract：:The ongoing epidemic of Zika virus (ZIKV) illustrates the importance of flaviviruses as emerging human pathogens. All vector-borne flaviviruses studied thus far have to overcome type I interferon (IFN) to replicate and cause disease in vertebrates. The mechanism(s) by which ZIKV antagonizes IFN signaling is unknown. H...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2016.05.009

    authors： Grant A,Ponia SS,Tripathi S,Balasubramaniam V,Miorin L,Sourisseau M,Schwarz MC,Sánchez-Seco MP,Evans MJ,Best SM,García-Sastre A

    更新日期：2016-06-08 00:00:00

  • New pieces for the malaria liver stage puzzle: where will they fit?

    abstract：:Malaria starts with the infection of the liver by Plasmodium parasites. Although extensive analysis of Plasmodium has revealed the expression patterns of this parasite in every stage of its life cycle, the liver stage remained unexplored. Recently, Tarun et al. have published the first complete transcriptome and prote...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2008.01.004

    authors： Mota MM,Rodriguez A

    更新日期：2008-02-14 00:00:00

  • Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.

    abstract：:Type I interferons (IFNs-I) fulfil multiple protective functions during pathogenic infections, but they can also cause detrimental effects and enhance immunopathology. Here, we report that IFNs-I promote the dysregulation of iron homeostasis in macrophages during systemic infections with the intracellular pathogen Can...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.01.023

    authors： Riedelberger M,Penninger P,Tscherner M,Seifert M,Jenull S,Brunnhofer C,Scheidl B,Tsymala I,Bourgeois C,Petryshyn A,Glaser W,Limbeck A,Strobl B,Weiss G,Kuchler K

    更新日期：2020-03-11 00:00:00

  • Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity.

    abstract：:Periodontitis is a common disease that is characterized by resorption of the alveolar bone and mediated by commensal bacteria that trigger host immune responses and bone destruction through unidentified mechanisms. We report that Nod1, an innate intracellular host receptor for bacterial peptidoglycan-related molecules...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2013.04.005

    authors： Jiao Y,Darzi Y,Tawaratsumida K,Marchesan JT,Hasegawa M,Moon H,Chen GY,Núñez G,Giannobile WV,Raes J,Inohara N

    更新日期：2013-05-15 00:00:00

  • Copper in microbial pathogenesis: meddling with the metal.

    abstract：:Transition metals such as iron, zinc, copper, and manganese are essential for the growth and development of organisms ranging from bacteria to mammals. Numerous studies have focused on the impact of iron availability during bacterial and fungal infections, and increasing evidence suggests that copper is also involved ...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2012.01.009

    authors： Samanovic MI,Ding C,Thiele DJ,Darwin KH

    更新日期：2012-02-16 00:00:00

  • HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I.

    abstract：:HIV-1 Nef, which is required for the efficient onset of AIDS, enhances viral replication and infectivity by exerting multiple effects on infected cells. Nef downregulates cell-surface MHC-I molecules by an uncharacterized PI3K pathway requiring the actions of two Nef motifs-EEEE(65) and PXXP(75). We report that the Ne...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2007.03.004

    authors： Hung CH,Thomas L,Ruby CE,Atkins KM,Morris NP,Knight ZA,Scholz I,Barklis E,Weinberg AD,Shokat KM,Thomas G

    更新日期：2007-04-19 00:00:00

  • This bud's for Vpu.

    abstract：:Successful viruses must overcome the body's immune defenses. In this issue of Cell Host & Microbe, Goffinet et al. (2009) provide evidence that the host protein CD317, the target of the HIV Vpu protein, is part of an ancient innate immune response directed against budding viruses. ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2009.02.002

    authors： Collins KL

    更新日期：2009-03-19 00:00:00

  • A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells.

    abstract：:Influenza A virus (IAV) infection is initiated by the attachment of the viral glycoprotein hemagglutinin (HA) to sialic acid on the host cell surface. However, the sialic acid-containing receptor crucial for IAV infection has remained unidentified. Here, we show that HA binds to the voltage-dependent Ca2+ channel Cav1...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2018.04.015

    authors： Fujioka Y,Nishide S,Ose T,Suzuki T,Kato I,Fukuhara H,Fujioka M,Horiuchi K,Satoh AO,Nepal P,Kashiwagi S,Wang J,Horiguchi M,Sato Y,Paudel S,Nanbo A,Miyazaki T,Hasegawa H,Maenaka K,Ohba Y

    更新日期：2018-06-13 00:00:00

  • NMD: nonsense-mediated defense.

    abstract：:Initially described as an RNA surveillance pathway, nonsense-mediated decay (NMD) is also recognized to function in the regulation of host gene expression. In this issue of Cell Host & Microbe, three studies describe NMD-mediated defense strategies of plants and mammalian cells in response to pathogen infection. ...

    journal_title：Cell host & microbe

    pub_type： 评论,杂志文章

    doi：10.1016/j.chom.2014.08.015

    authors： Wachter A,Hartmann L

    更新日期：2014-09-10 00:00:00

  • Inducible Germline IgMs Bridge Trypanosome Lytic Factor Assembly and Parasite Recognition.

    abstract：:Trypanosomiasis is a devastating neglected tropical disease affecting livestock and humans. Humans are susceptible to two Trypanosoma brucei subspecies but protected from other trypanosomes by circulating high-density lipoprotein (HDL) complexes called trypanosome lytic factors (TLFs) 1 and 2. TLFs contain apolipoprot...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2020.04.012

    authors： Verdi J,Zipkin R,Hillman E,Gertsch RA,Pangburn SJ,Thomson R,Papavasiliou N,Sternberg J,Raper J

    更新日期：2020-07-08 00:00:00

  • A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle.

    abstract：:A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s) was identified in malaria parasites. This family includes sequence-specific transcription factors that are key regulators of development. However, functions for the majority of ApiAP2 genes remain unknown. Here, a systematic knockou...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2016.12.003

    authors： Modrzynska K,Pfander C,Chappell L,Yu L,Suarez C,Dundas K,Gomes AR,Goulding D,Rayner JC,Choudhary J,Billker O

    更新日期：2017-01-11 00:00:00

  • Durable protection from Herpes Simplex Virus-2 transmission following intravaginal application of siRNAs targeting both a viral and host gene.

    abstract：:A vaginal microbicide should prevent pathogen transmission without disrupting tissue barriers to infection. Ideally, it would not need to be applied immediately before sexual intercourse, when compliance is a problem. Intravaginal administration of small interfering RNA (siRNA) lipoplexes targeting Herpes Simplex Viru...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2008.12.003

    authors： Wu Y,Navarro F,Lal A,Basar E,Pandey RK,Manoharan M,Feng Y,Lee SJ,Lieberman J,Palliser D

    更新日期：2009-01-22 00:00:00

  • Bacterial Adaptation to the Host's Diet Is a Key Evolutionary Force Shaping Drosophila-Lactobacillus Symbiosis.

    abstract：:Animal-microbe facultative symbioses play a fundamental role in ecosystem and organismal health. Yet, due to the flexible nature of their association, the selection pressures that act on animals and their facultative symbionts remain elusive. Here we apply experimental evolution to Drosophila melanogaster associated w...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2018.06.001

    authors： Martino ME,Joncour P,Leenay R,Gervais H,Shah M,Hughes S,Gillet B,Beisel C,Leulier F

    更新日期：2018-07-11 00:00:00

  • Importance of glycans to the host-bacteroides mutualism in the mammalian intestine.

    abstract：:Much of the mutualistic relationship between humans and their resident intestinal Bacteroides species is founded on glycans. The host provides plant polysaccharides and host-derived glycans and, in return, receives beneficial end products of bacterial fermentation. Glycans from the bacteria themselves are required for...

    journal_title：Cell host & microbe

    pub_type： 杂志文章,评审

    doi：10.1016/j.chom.2009.05.010

    authors： Comstock LE

    更新日期：2009-06-18 00:00:00

  • Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects.

    abstract：:The RNAi pathway confers antiviral immunity in insects. Virus-specific siRNA responses are amplified via the reverse transcription of viral RNA to viral DNA (vDNA). The nature, biogenesis, and regulation of vDNA are unclear. We find that vDNA produced during RNA virus infection of Drosophila and mosquitoes is present ...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2018.02.001

    authors： Poirier EZ,Goic B,Tomé-Poderti L,Frangeul L,Boussier J,Gausson V,Blanc H,Vallet T,Loyd H,Levi LI,Lanciano S,Baron C,Merkling SH,Lambrechts L,Mirouze M,Carpenter S,Vignuzzi M,Saleh MC

    更新日期：2018-03-14 00:00:00

  • miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation.

    abstract：:The liver-specific microRNA, miR-122, stabilizes hepatitis C virus (HCV) RNA genomes by recruiting host argonaute 2 (AGO2) to the 5' end and preventing decay mediated by exonuclease Xrn1. However, HCV replication requires miR-122 in Xrn1-depleted cells, indicating additional functions. We show that miR-122 enhances HC...

    journal_title：Cell host & microbe

    pub_type： 杂志文章

    doi：10.1016/j.chom.2014.12.014

    authors： Masaki T,Arend KC,Li Y,Yamane D,McGivern DR,Kato T,Wakita T,Moorman NJ,Lemon SM

    更新日期：2015-02-11 00:00:00