HIV Latency: Stochastic across Multiple Scales.

Abstract:

:Proviral latency is a major barrier to a cure for HIV. In this issue of Cell Host & Microbe, Hataye et al. (2019) show that reactivation of HIV latency is a non-deterministic, highly stochastic (i.e., noisy) process and propose that stochastic transitions to exponential viral expansion require a critical threshold of virus.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Hansen MMK,Martin B,Weinberger LS

doi

10.1016/j.chom.2019.11.010

subject

Has Abstract

pub_date

2019-12-11 00:00:00

pages

703-705

issue

6

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(19)30592-X

journal_volume

26

pub_type

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