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Carving a Niche for Antibacterial α-Defensins when Craving.

Abstract：

:In this issue of Cell Host & Microbe, Liang et al. (2019) show that α-defensins in the gastrointestinal tract sustain defenses to enteric pathogens during starvation. mTOR-dependent sensing of nutrient loss promotes production of an α-defensin regulator, which sustains α-defensin levels, loss of which increases lethality during bacterial infection.

journal_name

Cell Host Microbe

journal_title

Cell host & microbe

authors

Foerster EG,Girardin SE

doi

10.1016/j.chom.2019.04.009

subject

Has Abstract

pub_date

2019-05-08 00:00:00

pages

632-634

issue

5

eissn

1931-3128

issn

1934-6069

pii

S1931-3128(19)30212-4

journal_volume

25

pub_type

评论,杂志文章

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