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Double-spin-echo diffusion weighting with a modified eddy current adjustment.

Abstract：

:Magnetic field inhomogeneities like eddy current-related gradient fields cause geometric distortions in echo-planar imaging (EPI). This in particular affects diffusion-weighted imaging where these distortions vary with the direction of the diffusion weighting and hamper the accurate determination of diffusion parameters. The double-spin-echo preparation often used aims to reduce the cumulative eddy current effect by adjusting the diffusion-weighting gradient pulse durations to the time constant of the dominant eddy current contribution. However, eddy currents with a variety of time constants may be present and cause residual distortions. Here, a modification is proposed where the two bipolar gradient pairs of the preparation are adjusted independently to different time constants. At the expense of a slightly prolonged echo time, residual geometric distortions and correspondingly increased values of the diffusion anisotropy can be reduced as is demonstrated in phantoms and the human brain. Thus, it may help to improve the reliability of diffusion-weighted EPI.

journal_name

Magn Reson Imaging

journal_title

Magnetic resonance imaging

authors

Finsterbusch J

doi

10.1016/j.mri.2009.12.004

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

434-40

issue

3

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(09)00296-3

journal_volume

28

pub_type

杂志文章

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