Abstract:
PURPOSE:The detection of small parenchymal hepatic lesions identified by preoperative imaging remains a challenge for traditional pathologic methods in large specimens. We developed a magnetic resonance imaging (MRI) compatible localization device for imaging of surgical specimens aimed to improve identification and localization of hepatic lesions ex vivo. MATERIALS AND METHODS:The device consists of two stationary and one removable MR-visible grids lined with silicone gel, creating an orthogonal 3D matrix for lesion localization. To test the device, five specimens of swine liver with a random number of lesions created by microwave ablation were imaged on a 3T MR scanner. Two readers independently evaluated lesion coordinates and size, which were then correlated with sectioning guided by MR imaging. RESULTS:All lesions (n=38) were detected at/very close to the expected localization. Inter-reader agreement of lesion localization was almost perfect (0.92). The lesion size estimated by MRI matched macroscopic lesion size in cut specimen (±2mm) in 34 and 35, respectively, out of 38 lesions. CONCLUSION:Use of this MR compatible device for ex vivo imaging proved feasible for detection and three-dimensional localization of liver lesions, and has potential to play an important role in the ex vivo examination of surgical specimens in which pathologic correlation is clinically important.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Kinner S,Schubert TB,Nocerino EA,Hynes S,Colgan TJ,Loeffler AG,Brace C,Reeder SB,Winslow Edoi
10.1016/j.mri.2016.11.021subject
Has Abstractpub_date
2017-04-01 00:00:00pages
159-163eissn
0730-725Xissn
1873-5894pii
S0730-725X(16)30234-Xjournal_volume
37pub_type
杂志文章abstract:PURPOSE:To evaluate the use of the double-echo steady-state (DESS) sequence for acquiring high-resolution breast images with diffusion and T2 weighting. MATERIALS AND METHODS:Phantom scans were used to verify the T2 and diffusion weighting of the DESS sequence. Image distortion was evaluated in volunteers by comparing...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.12.014
更新日期:2014-05-01 00:00:00
abstract::We assessed the magnetic resonance (MR) imaging characteristics of two categories of epileptogenic substrates, neoplasms, and vascular malformations, to determine MR sensitivity and typical imaging features. A blinded retrospective analysis was performed on MR scans from 41 patients who had a neoplasm or vascular malf...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(95)02026-p
更新日期:1995-01-01 00:00:00
abstract::Forty-two patients with clinically suspected osteomyelitis were examined using magnetic resonance imaging (MRI). Twenty-seven patients (64%) had previous surgery or fracture, and 15 (36%) were referred for differentiation of acute osteomyelitis from bone tumors or other pathologic conditions. MRI was compared with com...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(85)90350-9
更新日期:1985-01-01 00:00:00
abstract::New methods for acquiring and processing gradient NMR well log data enable signals from gas, light oil, and water to be unambiguously separated and, in many cases, quantified. These methods exploit the combined effects of T1-based and diffusion-based contrast on log response. T1 contrast, which separates the water and...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00162-2
更新日期:1996-01-01 00:00:00
abstract::This study describes the appearance of Brenner tumors on MR imaging and compares quantitative signal intensity measurements of Brenner tumors with that of other ovarian tumors. A search of pathologic and MR records disclosed patients who had MRIs showing Brenner tumors prior to surgical excision. Patients (21) with ot...
journal_title:Magnetic resonance imaging
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0730-725x(98)00136-2
更新日期:1998-12-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) research has shown that brain arteriovenous malformations (AVMs) lead to reorganization of cortical motor areas. Since it is known that blood oxygenation level-dependent signal in fMRI may be influenced by the hemodynamic perturbation associated with the presence of the AVM...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2009.05.029
更新日期:2009-12-01 00:00:00
abstract::The value of NMR spectrometry as a way to understand the porosity and permeability of rocks is well documented. Other more esoteric parameters, such as restrictive diffusion, grain size distribution, and fluid viscosities have received less notice but are also available from the NMR measurements as laboratory studies ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)91537-7
更新日期:1994-01-01 00:00:00
abstract::The purpose of this study is to report the significant differences found in the identification of lesions in cervical spinal cord of two patients with multiple sclerosis when using the BLADE T2-TSE and BLADE T2-TIRM sequences as opposed to the conventional T2-TSE and T2-TIRM sequences for sagittal acquisition at 1.5T....
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.07.008
更新日期:2013-12-01 00:00:00
abstract::The purpose of this study was to evaluate the value of Ferumoxide-enhanced magnetic resonance (MR) imaging in the detection of hepatic metastases in high-risk patients treated for colorectal cancer that have rising CEA. We used 19 patients treated previously for colorectal cancer with rising CEA levels underwent an un...
journal_title:Magnetic resonance imaging
pub_type: 临床试验,杂志文章
doi:10.1016/s0730-725x(99)00134-4
更新日期:2000-04-01 00:00:00
abstract:INTRODUCTION:Previous investigations of test-retest reliability of cerebral blood flow (CBF) at rest measured with pseudo-continuous Arterial Spin Labeling (pCASL) demonstrated good reliability, but are limited by the use of similar scanner platforms. In the present study we examined test-retest reliability of CBF in r...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.09.004
更新日期:2018-01-01 00:00:00
abstract::Acetaminophen (APAP) toxicity is responsible for approximately half of all cases of acute liver failure in the United States. The mouse model of APAP toxicity is widely used to examine mechanisms of APAP toxicity. Noninvasive approaches would allow for serial measurements in a single animal to study the effects of exp...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2011.09.023
更新日期:2012-02-01 00:00:00
abstract::B(1) Field inhomogeneity and the relative effects of dielectric resonances are analyzed within the context of ultra high field MRI. This is accomplished by calculating the electromagnetic fields inside spherical phantoms and within a human head model in the presence and absence of an RF coil. These calculations are th...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(01)00300-9
更新日期:2001-02-01 00:00:00
abstract::Before it is possible to use MR imaging to investigate changes in the hippocampus in disease processes such as epilepsy and memory disorders, it is imperative that normal variations are defined. Using specific anatomic locations, we evaluated the hippocampi of 29 normal volunteers with coronal MR studies. Mild variati...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(91)90035-k
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To develop a method for estimating metabolite concentrations using phased-array coils and sensitivity-encoded (SENSE) magnetic resonance spectroscopic images (MRSI) of the human brain. MATERIALS AND METHODS:The method is based on the phantom replacement technique and uses receive coil sensitivity maps and body...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2009.11.003
更新日期:2010-04-01 00:00:00
abstract::The purpose of this study was to develop a method to determine time discrepancies between input and myocardial time-signal intensity (TSI) curves for accurate estimation of myocardial perfusion with first-pass contrast-enhanced MRI. Estimation of myocardial perfusion with contrast-enhanced MRI using kinetic models req...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.06.015
更新日期:2015-11-01 00:00:00
abstract::Multiparametric MRI is a remarkable imaging method for the assessment of patho-physiological processes. In particular, brain tumor characterization has taken advantage of the development of advanced techniques such as Diffusion- (DWI) and Perfusion- (PWI) Weighted Imaging, but a thorough analysis of meningiomas is sti...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.12.003
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:To characterize capillary perfusion and tissue diffusion changes in transplant renal artery stenosis (TRAS) with diffusion-weighted imaging (DWI). MATERIALS & METHODS:We retrospectively identified 30 patients with non-contrast enhanced magnetic resonance angiography-proven TRAS. Another 20 kidney transplant ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.05.007
更新日期:2019-07-01 00:00:00
abstract::Signal-to-noise ratio (SNR) is a critical factor in MR-guided high-intensity focused ultrasound (HIFU) for local heating, which can affect the accuracy of temperature measurement. In order to achieve high SNR and higher temporal resolution, dedicated coil arrays for MR-guided HIFU applications need to be developed. In...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.10.008
更新日期:2020-01-01 00:00:00
abstract::Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is often used to examine vascular function in malignant tumors and noninvasively monitor drug efficacy of antivascular therapies in clinical studies. However, complex numerical methods used to derive tumor physiological properties from DCE-MRI images can b...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.09.007
更新日期:2013-05-01 00:00:00
abstract::In this manuscript, fast and clinically feasible model-based bootstrapping algorithms using a geometrically constrained two-tensor diffusion model are employed for estimating uncertainty in fiber orientation. A Monte-Carlo-based tensor morphology voxel classification algorithm is initially applied using single-tensor ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.07.004
更新日期:2013-02-01 00:00:00
abstract::Fast magnetic resonance (MR) imaging provides a consistent and predictable appearance of vascular abnormalities as shown by four patients with thrombi, dissection and aneurysm. Fast MR images are obtained during breath-holding, resulting in an absence of respiratory motion artifacts. The time of MR study is much less ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(88)90483-3
更新日期:1988-07-01 00:00:00
abstract::With the conventional 3D MR angiographic sequences, it is difficult to prescribe multiple phases in different orientations, though multiple phases may be prescribed in the same orientation as the initial scan. Magnetic resonance angiography (MRA) was performed in which three slabs were prescribed in different orientat...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00003-x
更新日期:1999-07-01 00:00:00
abstract::A variety of shortcomings are associated with most currently used gastrointestinal contrast agents for magnetic resonance imaging (MRI). Artifacts resulting from peristalsis and other motions in the abdominal region are produced by many positive contrast agents (which increase signal intensity). Although this is not a...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(97)00020-9
更新日期:1997-01-01 00:00:00
abstract::A simple model for estimating temperature distribution within the frozen region during cryo ablation was tested for accuracy. Freezing experiments were conducted in both ex vivo and in vivo porcine livers. Temperature was measured during freezing using a fiber-optic temperature sensor. Three-dimensional MR images were...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(01)00389-7
更新日期:2001-06-01 00:00:00
abstract::We propose a new method to determine wettability indices from NMR relaxometry. The new method uses the sensitivity of low field NMR relaxometry to the fluid distribution in oil-water saturated porous media. The model is based on the existence of a surface relaxivity for both oil and water, allowing the determination o...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(03)00145-0
更新日期:2003-04-01 00:00:00
abstract::The purpose of this study was to evaluate the diagnostic potential of a high-resolution magnetic resonance (MR) venography technique in patients with cerebral arteriovenous malformations (AVMs). A high-resolution 3D gradient echo sequence was used with a long echo time TE to obtain venous information down to sub-pixel...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00084-3
更新日期:1999-12-01 00:00:00
abstract::Gd-DOTA contrast enhancement of MR images was evaluated on induced mammary tumors in female rats. A single intravenous injection of the carcinogenic N-nitrosourea ENU was administered to Wistar rats; this simple treatment led to a high percentage of mammary tumors without causing death. All the induced tumors were ade...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(90)90215-n
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:To describe the patterns of bile distribution in the biliary tree, duodenum, jejunum, and stomach, and to determine the gallbladder ejection fraction (GBEF) by using functional magnetic resonance cholangiography (MRC) with gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA) in healthy vol...
journal_title:Magnetic resonance imaging
pub_type: 临床试验,杂志文章
doi:10.1016/j.mri.2014.01.003
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To introduce a simple analytical formula for estimating T2 from a single Double-Echo in Steady-State (DESS) scan. METHODS:Extended Phase Graph (EPG) modeling was used to develop a straightforward linear approximation of the relationship between the two DESS signals, enabling accurate T2 estimation from one DES...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.12.018
更新日期:2017-05-01 00:00:00
abstract::The amplitudes of gradient-echoes produced using static field gradients are sensitive to diffusion of tissue water during the echo evolution time. Gradient-echoes have been used to produce MR images in which image intensity is proportional to the self-diffusion coefficient of water. However, such measurements are subj...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(95)00051-h
更新日期:1995-01-01 00:00:00