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In vivo mapping of functional domains and axonal connectivity in cat visual cortex using magnetic resonance imaging.

Abstract：

:Noninvasive cognitive neuroimaging studies based on functional magnetic resonance imaging (fMRI) are of ever-increasing importance for basic and clinical neurosciences. The explanatory power of fMRI could be greatly expanded, however, if the pattern of the neuronal circuitry underlying functional activation could be made visible in an equally noninvasive manner. In this study, blood oxygenation level-dependent (BOLD)-based fMRI and diffusion tensor imaging (DTI) were performed in the same cat visual cortex, and the foci of fMRI activation utilized as seeding points for 3D DTI fiber reconstruction algorithms, thus providing the map of the axonal circuitry underlying visual information processing. The methods developed in this study will lay the foundation for in vivo neuroanatomy and the ability for noninvasive longitudinal studies of brain development.

journal_name

Magn Reson Imaging

journal_title

Magnetic resonance imaging

authors

Kim DS,Kim M,Ronen I,Formisano E,Kim KH,Ugurbil K,Mori S,Goebel R

doi

10.1016/j.mri.2003.08.014

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

1131-40

issue

10

eissn

0730-725X

issn

1873-5894

pii

S0730725X03003242

journal_volume

21

pub_type

杂志文章

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