Abstract:
:Pathologically, hippocampal sclerosis (HS) is characterized by neuronal loss and gliosis affecting particularly the pyramidal neurons of CA1, CA3, and CA4 with relative sparing of the CA2 neurons. This can be identified in vivo with magnetic resonance (MR) imaging techniques that can reveal both morphological and signal abnormalities. The morphological changes are atrophy and loss of the normal internal architecture of the hippocampus as seen in coronal section. There is also T1- and T2-weighted signal abnormality in the hippocampus. Quantitative techniques are very good at measuring any single one of these features, but the spectrum of HS includes cases in which a single feature can occasionally be misleading. Also, quantitation focuses entirely on the hippocampus, and it is becoming clear that HS may exist in the presence of other brain pathology that may affect proper management of the patient. Therefore, quantitative measures should always be interpreted in the context of optimised imaging sequences and visual inspection. For routine clinical purposes, the relative reliance on quantitation (hippocampal volume or T2 measurements) depends entirely on the yield of visual inspection in any institution. This, in turn, depends on whether optimised imaging is performed and on the familiarity of the reporting specialist with the MRI features of HS. A technique which approaches 95-100% compared with pathology is essential in any epilepsy centre, and optimised visual analysis can achieve this. There are some cases where quantitation of a single feature can be misleading, so visual analysis should always be performed, and complements any quantitative study.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Jackson GDdoi
10.1016/0730-725x(95)02016-msubject
Has Abstractpub_date
1995-01-01 00:00:00pages
1081-93issue
8eissn
0730-725Xissn
1873-5894pii
0730-725X(95)02016-Mjournal_volume
13pub_type
杂志文章,评审abstract::Hippocampal metabolite concentrations were determined by localized in vivo proton magnetic resonance spectroscopy (1H MRS) in eleven patients suffering from refractory mesial temporal lobe epilepsy (MTLE), as well as in eleven age-matched healthy volunteers, and compared with patient history, postoperative outcome and...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00123-4
更新日期:1998-10-01 00:00:00
abstract::Dysfunction of the corticolimbic circuitry has been highlighted in social anxiety disorder (SAD) during social stimuli. However, few studies have investigated functional connectivity in SAD during the resting state, which may improve our understanding of SAD pathophysiology. The aim of this study was to investigate wh...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2011.02.013
更新日期:2011-06-01 00:00:00
abstract::In recent years there has been increasing interest in applying magnetic resonance (MR) techniques in areas of engineering and chemical technology. The science that underpins many of these applications is the physics and chemistry of transport and reaction processes in porous materials. Key to the exploitation of MR me...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(03)00127-9
更新日期:2003-04-01 00:00:00
abstract:PURPOSE:Intramuscular fat infiltration is a dynamic process, in response to exercise and muscle health, which can be quantified by estimating fat fraction (FF) from Dixon MRI. Healthy hip abductor muscles are a good indicator of a healthy hip and an active lifestyle as they have a fundamental role in walking. The autom...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2020.06.019
更新日期:2020-10-01 00:00:00
abstract::The proton spin-lattice relaxation measured at several frequencies leads to a resolved distribution of four Tli for reactive powder concrete (RPC). The typical Tli frequency dependences are quantitatively interpreted by a biphasic fast exchange model and a proton nuclear relaxation of hydrated paramagnetic ions at the...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00063-0
更新日期:1998-06-01 00:00:00
abstract::The purpose of this study was to analyze background parenchymal enhancement (BPE) in the contralateral normal breast of cancer patients during the course of neoadjuvant chemotherapy (NAC). Forty-five subjects were analyzed. Each patient had three MRIs, one baseline (B/L) and two follow-up (F/U) studies. The fibrogland...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.07.014
更新日期:2013-11-01 00:00:00
abstract::The radiologic findings from 60 patients with 86 internally deranged temporomandibular joints (TMJ) upon whom sequential imaging procedures had been performed over a period of two months to ten years were analyzed and correlated with clinical, surgical (72 joints), and pathological observations. Internal derangement o...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(89)90404-9
更新日期:1989-09-01 00:00:00
abstract::Biliary cystadenomas and their malignant counterparts, biliary cystadenocarcinomas, are rare cystic tumors that arise from hepatobiliary epithelium. Ultrasound (US) and computed tomography (CT) are the initial imaging modalities used for the evaluation of biliary cystic tumors, but are not specific. MRI and MRCP, beca...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(01)00453-2
更新日期:2001-11-01 00:00:00
abstract::Quantitative measures of rheumatoid arthritis (RA) disease progression can provide valuable tools for evaluation of new treatments during clinical trials. In this study, a novel multispectral (MS) MRI analysis method is presented to quantify changes in bone lesion volume (DeltaBLV) in the hands of RA patients. Image r...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2004.01.013
更新日期:2004-05-01 00:00:00
abstract::An understanding of the nucleation and growth mechanism of methane hydrate in porous space is essential for exploitation and application of hydrates, but the mechanism is yet to be clarified. Magnetic resonance imaging (MRI) was employed to visually analyze the spatial and temporal formation behavior of methane hydrat...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.06.005
更新日期:2019-09-01 00:00:00
abstract::Arterial spin labeling (ASL) perfusion fMRI data differ in important respects from the more familiar blood oxygen level-dependent (BOLD) fMRI data and require specific processing strategies. In this paper, we examined several factors that may influence ASL data analysis, including data storage bit resolution, motion c...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2007.07.003
更新日期:2008-02-01 00:00:00
abstract::To determine if magnetic resonance imaging (MRI) can be used to detect tissue viability in segments with persistent 201T1 defects early following acute myocardial infarction, 24 patients underwent MRI and adenosine 201T1 single photon emission computed tomography (SPECT) imaging at approximately 6 days. Infarction was...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(93)90214-x
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To establish an optimized sequence design for fast acceleration of arterial spin labeling (ASL)-based time-resolved magnetic resonance angiography (MRA) by acquisition of control and labeled images in the same shot (fast ACTRESS) and a scan time of <1min, for the evaluation of intracranial vessels. MATERIALS A...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.07.026
更新日期:2017-11-01 00:00:00
abstract::Spiral acquisition schemes offer unique advantages such as flow compensation, efficient k-space sampling and robustness against motion that make this option a viable choice among other non-Cartesian sampling schemes. For this reason, the main applications of spiral imaging lie in dynamic magnetic resonance imaging suc...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
doi:10.1016/j.mri.2010.03.036
更新日期:2010-07-01 00:00:00
abstract::In congenital diaphragmatic hernia (CDH), lung hypoplasia and secondary pulmonary hypertension are the major causes of death and severe disability. Based on new therapeutic strategies survival rates could be improved to up to 80%. However, after surgical repair of CDH, long-term follow-up of these pediatric patients i...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.08.003
更新日期:2015-12-01 00:00:00
abstract::Acrylamide gel loaded with phosphate has been used in two compartment phantoms designed to assess localized spectroscopy techniques. A chemical shift difference of 2.3 ppm was produced by changing the pH from 6 to 8.9. The 31P relaxation times were modified by doping the gels with paramagnetic ions. For a T1 of approx...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(92)90381-9
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to investigate the correlation between the liver kinetics of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) and liver histopathology in a mouse model of NASH by using dynamic contrast-enhanced MRI. MATERIALS AND METHODS:Twenty male C57/BL6 mice aged 8we...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.03.009
更新日期:2016-07-01 00:00:00
abstract::More than a dozen Nuclear Magnetic Resonance (NMR) imaging methods have been described using different radio-frequency pulse sequences, magnetic field gradient variations, and data processing. In order to have a theoretical understanding in the most general case, we have conceived a computer program for the simulation...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(84)90065-1
更新日期:1984-01-01 00:00:00
abstract::Idiopathic dilatation of the pulmonary artery (IDPA) is a rare congenital disease which is usually detected fortuitously on chest x-ray, thus radiologists must be aware of this clinical entity. This report describes four cases to which Magnetic Resonance Imaging (MRI) played a major role in diagnosing IDPA and in dete...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00013-2
更新日期:1999-07-01 00:00:00
abstract::Increased bone water content resulting from repetitive patellofemoral joint overloading has been suggested to be a possible mechanism underlying patellofemoral pain (PFP). To date, it remains unknown whether persons with PFP exhibit elevated bone water content. The purpose of this study was to determine whether recrea...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2014.04.018
更新日期:2014-09-01 00:00:00
abstract::Metabolic imaging of hyperpolarized [1-(13)C] pyruvate co-polarized with [(13)C]urea by dynamic nuclear polarization with rapid dissolution is a promising new method for assessing tumor metabolism and perfusion simultaneously in vivo. Novel pulse sequences are required to enable dynamic imaging of multiple (13)C spect...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.037
更新日期:2013-02-01 00:00:00
abstract::Magnetic resonance imaging (MRI) is a completely noninvasive modality that has shown significant promise for the evaluation of the cardiovascular system. Our imaging technique employed electrocardiographic (ECG) gating, which resulted in well-resolved images of the cardiac structures. Patients and animals with a varie...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(84)90002-x
更新日期:1984-01-01 00:00:00
abstract::The ability to evaluate empirical diffusion MRI acquisitions for quality and to correct the resulting imaging metrics allows for improved inference and increased replicability. Previous work has shown promise for estimation of bias and variance of generalized fractional anisotropy (GFA) but comes at the price of compu...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.03.021
更新日期:2019-06-01 00:00:00
abstract::The amplitudes of gradient-echoes produced using static field gradients are sensitive to diffusion of tissue water during the echo evolution time. Gradient-echoes have been used to produce MR images in which image intensity is proportional to the self-diffusion coefficient of water. However, such measurements are subj...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(95)00051-h
更新日期:1995-01-01 00:00:00
abstract::A 31-year-old male patient had a transjugular intrahepatic portal systemic shunt (TIPS) placed for acute Budd-Chiari syndrome secondary to paroxysmal nocturnal hemoglobinuria (PNH). Post-procedure, he was anticoagulated for his underlying paroxysmal nocturnal hemoglobinuria. After 11 days, he complained of upper abdom...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00081-2
更新日期:1998-09-01 00:00:00
abstract:INTRODUCTION:Compared to standard arterial-only first-pass MR-angiography (FPMRA), imaging during the equilibrium phase of a blood pool contrast agent (steady state) has been shown to provide higher image quality and better stenosis grading. Homogenous Dixon fat-suppression promises to increase contrast by suppression ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.07.005
更新日期:2015-11-01 00:00:00
abstract::Brain vascular damage accumulate in aging and often manifest as white matter hyperintensities (WMHs) on MRI. Despite increased interest in automated methods to segment WMHs, a gold standard has not been achieved and their longitudinal reproducibility has been poorly investigated. The aim of present work is to evaluate...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2020.11.008
更新日期:2021-02-01 00:00:00
abstract::Fast gradient echo sequences, such as echo planer imaging (EPI) and spiral imaging, are vulnerable to artifacts resulting from B(0) inhomogeneities. A major contribution to these artifacts is the susceptibility variation across the head, which is most severe in regions adjacent to air-tissue interfaces, such as the mo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2005.07.011
更新日期:2005-11-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) of the cortex is a powerful tool for neuroscience research, and its use has been extended into the brainstem and spinal cord as well. However, there are significant technical challenges with extrapolating the developments that have been achieved in the cortex to their use i...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2008.01.038
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:This study was done to test a series of MR sequences for evaluating the sciatic nerve after total hip arthroplasty (THA). MATERIAL AND METHODS:The study protocol was approved by the institutional review board. Informed consent was obtained from all patients. Twenty-five patients (11 men and 14 women mean age: ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2010.06.009
更新日期:2010-11-01 00:00:00