Abstract：
:Metabolic imaging of hyperpolarized [1-(13)C] pyruvate co-polarized with [(13)C]urea by dynamic nuclear polarization with rapid dissolution is a promising new method for assessing tumor metabolism and perfusion simultaneously in vivo. Novel pulse sequences are required to enable dynamic imaging of multiple (13)C spectral lines with high spatiotemporal resolution. The goal of this study was to investigate a new frequency-specific approach for rapid metabolic imaging of multiple (13)C resonances using the spectral selectivity of steady-state free precession pulse (SSFP) trains. Methods developed in simulations were implemented in a dynamic frequency-cycled balanced SSFP pulse sequence on a 14.1-T animal magnetic resonance imaging scanner. This acquisition was tested in thermal and hyperpolarized phantom imaging studies and in a transgenic mouse with prostate cancer.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
von Morze C,Sukumar S,Reed GD,Larson PE,Bok RA,Kurhanewicz J,Vigneron DBdoi
10.1016/j.mri.2012.06.037subject
Has Abstractpub_date
2013-02-01 00:00:00pages
163-70issue
2eissn
0730-725Xissn
1873-5894pii
S0730-725X(12)00247-0journal_volume
31pub_type
杂志文章abstract：:The current fMRI study investigated correlations of low-frequency signal changes in the left inferior frontal gyrus, right inferior frontal gyrus and cerebellum in 13 adult dyslexic and 10 normal readers to examine functional networks associated with these regions. The extent of these networks to regions associated wi...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.12.006
更新日期：2006-04-01 00:00:00
abstract：PURPOSE:To develop a free-running framework for 3D isotropic simultaneous myocardial T1/T2 mapping and cine imaging. METHODS:Continuous data acquisition with 3D golden angle radial trajectory is used in conjunction with T2 preparation of varying echo times and inversion recovery (IR) pulses to enable simultaneous myoc...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2019.08.008
更新日期：2019-11-01 00:00:00
abstract：:Functional MR imaging of the alert, behaving monkey is being used more and more often to detect activation patterns and guide electrophysiological research investigating the neural basis of behavior. Several labs have reported fMRI data from the awake monkey, but none of them has studied and systematically corrected t...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2007.03.002
更新日期：2007-07-01 00:00:00
abstract：:Tagged magnetic resonance imaging allows the noninvasive measurement of regional systolic myocardial deformations and helps localize ischemic regions in the left ventricle (LV). The objective of this study was to evaluate the potential accuracy of localizing ischemic regions in the LV using endocardial and epicardial ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(97)00161-6
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To perform comprehensive in vitro experiments using six-directional icosahedral flow encoding (ICOSA6) 4D flow magnetic resonance imaging (MRI) under various scan conditions to analyze the robustness of velocity and turbulence quantification. MATERIALS AND METHODS:In vitro flow phantoms with steady flow rates ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2020.06.020
更新日期：2020-10-01 00:00:00
abstract：:Combining electrical stimulation with fMRI (esfMRI) has proven to be an important tool to study the global effects of electrical stimulation on neural networks in the brain. Here we extend our previous studies to stimulating the upper superior temporal sulcus (STS) in the anesthetized monkey. Our results show that sti...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2011.04.005
更新日期：2011-12-01 00:00:00
abstract：:For a number of reasons, it is desirable to fabricate coils which, for a known current, shall produce predetermined values of the magnetic field intensity at a number of points within a nuclear magnetic resonance imager. The calculation of the magnetic field intensity at a set of points involves the integration of the...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(89)90524-9
更新日期：1989-11-01 00:00:00
abstract：:Glycosaminoglycan Chemical Exchange Saturation Transfer (gagCEST) is an important molecular MRI methodology developed to assess changes in cartilage GAG concentrations. The correction for B0 field inhomogeneity is technically crucial in gagCEST imaging. This study evaluates the accuracy of the B0 estimation determined...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2013.07.009
更新日期：2014-01-01 00:00:00
abstract：:The purpose of this study is to report the significant differences found in the identification of lesions in cervical spinal cord of two patients with multiple sclerosis when using the BLADE T2-TSE and BLADE T2-TIRM sequences as opposed to the conventional T2-TSE and T2-TIRM sequences for sagittal acquisition at 1.5T....
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2013.07.008
更新日期：2013-12-01 00:00:00
abstract：:Fatigue and impairment mobility are frequent problems in multiple sclerosis (MS). Despite its enormous potential, in vivo (1)H MRS of skeletal muscles for MS patients is a largely unexplored field. One fundamental question remains unanswered: whether MS can cause observable proton metabolite changes. High quality two-...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.01.005
更新日期：2004-04-01 00:00:00
abstract：:Hippocampal metabolite concentrations were determined by localized in vivo proton magnetic resonance spectroscopy (1H MRS) in eleven patients suffering from refractory mesial temporal lobe epilepsy (MTLE), as well as in eleven age-matched healthy volunteers, and compared with patient history, postoperative outcome and...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(98)00123-4
更新日期：1998-10-01 00:00:00
abstract：:In-plane flow quantification in MRI offers the potential for assessing vessel patency, and both volume flow rate and flow velocity. These techniques will have definite future impact on MR angiography. The method used in this paper employs motion artifact suppression technique (MAST) gradients to refocus spins travelli...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(88)90409-2
更新日期：1988-05-01 00:00:00
abstract：:In this contribution, we explore the potential of proton electron double resonance imaging (PEDRI) in environmental science (hydrogeological) applications. After a discussion of the hydrogeological motivation for studies of free radical transport in environmental matrices, we present results from first experiments tha...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.11.027
更新日期：2005-02-01 00:00:00
abstract：:A new magnetic resonance imaging technique was applied to the Taylor-Couette and spiral Poiseuille (Taylor-Couette with superposed mean axial flux) flows for the first time. The experimental technique is a combination of spatial tagging methods and a snapshot FLASH imaging sequence, which allows the full-field visuali...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(99)00121-6
更新日期：2000-02-01 00:00:00
abstract：:Multi-contrast magnetic resonance imaging (MRI) is a useful technique to aid clinical diagnosis. This paper proposes an efficient algorithm to jointly reconstruct multiple T1/T2-weighted images of the same anatomical cross section from partially sampled k-space data. The joint reconstruction problem is formulated as m...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2014.08.025
更新日期：2014-12-01 00:00:00
abstract：:The hippocampal formation is a brain system that is implicated in learning and memory. The major input to the hippocampus arrives from the entorhinal cortex (EC) to the dentate gyrus (DG) through the perforant path. In the present work, we have investigated the functional properties of this connection by concomitantly...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.02.018
更新日期：2008-09-01 00:00:00
abstract：:To assess whether magnetic resonance imaging could assist in diagnosing Ewing sarcoma, we retrospectively analyzed T1- and T2-weighted images of 24 consecutive solitary lytic bone lesions, including 18 cases of histologically proven Ewing sarcoma, and six aggressive-appearing benign lesions including eosinophilic gran...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(94)92450-3
更新日期：1994-01-01 00:00:00
abstract：:In vivo spin-lattice relaxation times, T1, of water and lipid protons of normal and atrophic muscles were measured, using the spatially resolved spectroscopy (SPARS) sequence, in a genetic avian model of myopathy. These T1 values were compared with those of the hypertrophic muscles. Although the water T1 values of mus...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(89)90550-x
更新日期：1989-05-01 00:00:00
abstract：PURPOSE:Time-of-flight (ToF) and phase contrast (PC) magnetic resonance angiographies (MRAs) are noninvasive applications to depict the cerebral arteries. Both approaches can image the cerebral vasculature without the administration of intravenous contrast. Therefore, it is used in routine clinical evaluation of cerebr...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.10.023
更新日期：2013-05-01 00:00:00
abstract：:A simple model for estimating temperature distribution within the frozen region during cryo ablation was tested for accuracy. Freezing experiments were conducted in both ex vivo and in vivo porcine livers. Temperature was measured during freezing using a fiber-optic temperature sensor. Three-dimensional MR images were...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(01)00389-7
更新日期：2001-06-01 00:00:00
abstract：PURPOSE:To evaluate the performance of combined integrated slice-by-slice shimming and readout-segmented EPI (irsEPI) for diffusion-weighted MR imaging (DWI) of the neck at 3Tesla. METHODS:This study was approved by the local ethics committee. An anthropometric phantom of the head/neck region incorporating compartment...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2017.05.004
更新日期：2017-10-01 00:00:00
abstract：:The value of NMR spectrometry as a way to understand the porosity and permeability of rocks is well documented. Other more esoteric parameters, such as restrictive diffusion, grain size distribution, and fluid viscosities have received less notice but are also available from the NMR measurements as laboratory studies ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(94)91537-7
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:To develop a method for estimating metabolite concentrations using phased-array coils and sensitivity-encoded (SENSE) magnetic resonance spectroscopic images (MRSI) of the human brain. MATERIALS AND METHODS:The method is based on the phantom replacement technique and uses receive coil sensitivity maps and body...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2009.11.003
更新日期：2010-04-01 00:00:00
abstract：:Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is currently the dominant technique for non-invasive investigation of brain functions. One of the challenges with BOLD fMRI, particularly at high fields, is compensation for the effects of spatiotemporally varying magnetic field inho...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2009.07.005
更新日期：2010-02-01 00:00:00
abstract：:The effect of slice orientation on reproducibility and sensitivity of 3T fMRI activation using a motor task has been investigated in six normal volunteers. Four slice orientations were used; axial, oblique axial, coronal and sagittal. We applied analysis of variance (ANOVA) to suprathreshold voxel statistics to quanti...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(01)00399-x
更新日期：2001-12-01 00:00:00
abstract：:The application of MRI-visible paramagnetic tracers to reveal in vivo connectivity can provide important subject-specific information for multisite, multielectrode intracortical recordings in combined behavioral and physiology experiments. To establish the use of such tracers in the nonhuman primate, we recently compa...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.12.031
更新日期：2006-05-01 00:00:00
abstract：:Currently, the North American symptomatic carotid endarterectomy trial, European carotid surgery trial, and common carotid method are used to measure the carotid stenosis for determining candidates for carotid endarterectomy using the projection angiography from different modalities such as digital subtraction angiogr...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.01.007
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:While PRESS is often employed to measure glutamate concentrations, MEGA-PRESS enables simultaneous Glx (glutamate and glutamine) and GABA measurements. This study aimed to compare validation, repeatability, and concordance of different approaches for glutamate quantification at 3T to aid future studies in their...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2017.12.029
更新日期：2018-05-01 00:00:00
abstract：:The anticancer effect of thiacarpine, a synthetic analogue of the known cytotoxic alkaloid polycarpine isolated from the Pacific ascidian Polycarpa aurata, was investigated in vivo in experiments using mouse solid Ehrlich carcinoma tumor as the target. A high-resolution magnetic resonance imaging (MRI) technique using...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.01.014
更新日期：2008-07-01 00:00:00
abstract：:The development of NMR diffusion imaging and diffusion tensor imaging (DTI) has offered the possibility of studying the porous structures beyond anatomical imaging. In fact, random molecular motions, within tissue components, probe tissue microstructures. Up to now, the DTI method was mainly used to investigate cerebr...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.11.018
更新日期：2005-02-01 00:00:00
