Abstract:
:Hippocampal metabolite concentrations were determined by localized in vivo proton magnetic resonance spectroscopy (1H MRS) in eleven patients suffering from refractory mesial temporal lobe epilepsy (MTLE), as well as in eleven age-matched healthy volunteers, and compared with patient history, postoperative outcome and histopathology. Main results are: 1) In patients, the decrease in N-acetylaspartate (NAA) concentrations was highly significant ipsilateral, and less but still significant contralateral to the electroencephalogram-defined focus, as compared to controls. 2) The decrease in ipsilateral NAA measured preoperatively correlates with the degree of hippocampal sclerosis but 3) does not reliably predict postoperative outcome, although there is a trend toward better outcome in patients with a marked decrease of NAA. 4) Hippocampal NAA decrease (ipsi- and contralateral) is highly correlated with early onset age of epileptic seizures. 5) Among patients with similar onset age in early childhood, there is a strong association between duration of the disease and contralateral (and, though less clear-cut, ipsilateral) NAA loss. These results are concordant with the notion of a generally progressive worsening and complicating course of symptoms in poorly controlled MTLE.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Duc CO,Trabesinger AH,Weber OM,Meier D,Walder M,Wieser HG,Boesiger Pdoi
10.1016/s0730-725x(98)00123-4subject
Has Abstractpub_date
1998-10-01 00:00:00pages
969-79issue
8eissn
0730-725Xissn
1873-5894pii
S0730-725X(98)00123-4journal_volume
16pub_type
杂志文章abstract::This work addresses the special problems of measuring flow velocity distributions in rock by NMR methods. Specifically, these problems are to measure very slow flows as well as flows in the presence of background magnetic field gradients caused by heterogeneities of the rock. We modify a stimulated echo sequence for u...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
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journal_title:Magnetic resonance imaging
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更新日期:2011-12-01 00:00:00
abstract::It is a big challenge to segment magnetic resonance (MR) images with intensity inhomogeneity. The widely used segmentation algorithms are region based, which mostly rely on the intensity homogeneity, and could bring inaccurate results. In this paper, we propose a novel region-based active contour model in a variationa...
journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(97)00278-6
更新日期:1998-04-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
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更新日期:1992-01-01 00:00:00
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(87)90023-3
更新日期:1987-01-01 00:00:00
abstract::The evaluation of a solitary pulmonary nodule (SPN) is one of the most frequently encountered challenges in thoracic radiology. In addition to a "state-of-the-art" evaluation of SPNs with CT and biopsy techniques, recently the assessment of the enhancement characteristics with iodinized contrast agents has shown its p...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(95)02010-q
更新日期:1995-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.10.010
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:To compare the diagnostic performance of the noncontrast MRI including DWI to the standard MRI for detecting hepatic malignancies in patients with chronic liver disease. MATERIALS AND METHODS:We included 135 patients with 136 histologically-confirmed hepatocellular carcinomas (HCCs), 12 cholangiocarcinomas, an...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.12.021
更新日期:2014-07-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(93)90035-c
更新日期:1993-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.11.010
更新日期:2018-04-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00342-6
更新日期:1997-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)91547-4
更新日期:1994-01-01 00:00:00
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2011.04.005
更新日期:2011-12-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00159-3
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
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更新日期:1998-06-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2004.11.010
更新日期:2005-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00072-1
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.01.007
更新日期:2017-05-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.07.010
更新日期:2016-01-01 00:00:00
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.10.006
更新日期:2017-02-01 00:00:00
abstract::Resting fluctuations in arterial CO2 (a cerebral vasodilator) are believed to be an important source of low-frequency blood oxygenation level dependent (BOLD) signal fluctuations. In this study we focus on the two commonly used resting-states in functional magnetic resonance imaging experiments, eyes open and eyes clo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.013
更新日期:2013-04-01 00:00:00