esfMRI of the upper STS: further evidence for the lack of electrically induced polysynaptic propagation of activity in the neocortex.

Abstract:

:Combining electrical stimulation with fMRI (esfMRI) has proven to be an important tool to study the global effects of electrical stimulation on neural networks in the brain. Here we extend our previous studies to stimulating the upper superior temporal sulcus (STS) in the anesthetized monkey. Our results show that stimulating area V5/MT and surrounding areas leads to positive BOLD responses in the majority of cortical areas known to receive direct/monosynaptic connections from the stimulation site. We confirm our previous results from stimulating primary visual cortex that the propagation of electrically induced activity is limited in its transsynaptic propagation to the first synapse also for extrastriate areas.

journal_name

Magn Reson Imaging

authors

Sultan F,Augath M,Murayama Y,Tolias AS,Logothetis N

doi

10.1016/j.mri.2011.04.005

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1374-81

issue

10

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(11)00135-4

journal_volume

29

pub_type

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