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Spectral pattern of total creatine and trimethyl ammonium in multiple sclerosis.

Abstract：

:Fatigue and impairment mobility are frequent problems in multiple sclerosis (MS). Despite its enormous potential, in vivo (1)H MRS of skeletal muscles for MS patients is a largely unexplored field. One fundamental question remains unanswered: whether MS can cause observable proton metabolite changes. High quality two-dimensional in vivo (1)H MRS reveals that the spectral pattern of total creatine (tCr) and trimethyl ammonium (TMA) of soleus muscles of MS patients can be distinctively different from that of healthy volunteers, and in vivo (1)H MRS of skeletal muscles has a potential to become a useful tool in MS study.

journal_name

Magn Reson Imaging

journal_title

Magnetic resonance imaging

authors

Hu J,Xu Y,Jiang Q,Sehgal V,Shen Y,Xuan Y,Xia Y

doi

10.1016/j.mri.2004.01.005

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

427-9

issue

3

eissn

0730-725X

issn

1873-5894

pii

S0730725X04000232

journal_volume

22

pub_type

杂志文章

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