Abstract:
PURPOSE:To develop a method for estimating metabolite concentrations using phased-array coils and sensitivity-encoded (SENSE) magnetic resonance spectroscopic images (MRSI) of the human brain. MATERIALS AND METHODS:The method is based on the phantom replacement technique and uses receive coil sensitivity maps and body-coil loading factors to account for receive B(1) inhomogeneity and variable coil loading, respectively. Corrections for cerebrospinal fluid content from the MRSI voxel were also applied, and the total protocol scan time was less than 15 min. The method was applied to 10 normal human volunteers using a multislice 2D-MRSI sequence at 3 T, and seven different brain regions were quantified. RESULTS:N-Acetyl aspartate (NAA) concentrations varied from 9.7 to 14.7 mM, creatine (Cr) varied from 6.6 to 10.6 mM and choline (Cho) varied from 1.6 to 3.0 mM, in good general agreement with prior literature values. CONCLUSIONS:Quantitative SENSE-MRSI of the human brain is routinely possible using an adapted phantom-replacement technique. The method may also be applied to other MRSI techniques, including conventional phase encoding, with phased-array receiver coils, provided that coil sensitivity profiles can be measured.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Bonekamp D,Smith MA,Zhu H,Barker PBdoi
10.1016/j.mri.2009.11.003subject
Has Abstractpub_date
2010-04-01 00:00:00pages
305-13issue
3eissn
0730-725Xissn
1873-5894pii
S0730-725X(09)00281-1journal_volume
28pub_type
杂志文章abstract::Biliary cystadenomas and their malignant counterparts, biliary cystadenocarcinomas, are rare cystic tumors that arise from hepatobiliary epithelium. Ultrasound (US) and computed tomography (CT) are the initial imaging modalities used for the evaluation of biliary cystic tumors, but are not specific. MRI and MRCP, beca...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(01)00453-2
更新日期:2001-11-01 00:00:00
abstract::The objective of this study was to measure T2* values of the normal human lung in vivo during breathhold using a rapid gradient-echo sequence with ultra-short echo times (TE). A sagittal slice of the right lung was imaged in six volunteers with various TE ranging from 0.5 ms to 5 ms using a clinical 1.5 Tesla MR scann...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00047-8
更新日期:1999-09-01 00:00:00
abstract::To assess whether magnetic resonance imaging could assist in diagnosing Ewing sarcoma, we retrospectively analyzed T1- and T2-weighted images of 24 consecutive solitary lytic bone lesions, including 18 cases of histologically proven Ewing sarcoma, and six aggressive-appearing benign lesions including eosinophilic gran...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)92450-3
更新日期:1994-01-01 00:00:00
abstract::The proton spin-lattice relaxation measured at several frequencies leads to a resolved distribution of four Tli for reactive powder concrete (RPC). The typical Tli frequency dependences are quantitatively interpreted by a biphasic fast exchange model and a proton nuclear relaxation of hydrated paramagnetic ions at the...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00063-0
更新日期:1998-06-01 00:00:00
abstract::This study describes the appearance of Brenner tumors on MR imaging and compares quantitative signal intensity measurements of Brenner tumors with that of other ovarian tumors. A search of pathologic and MR records disclosed patients who had MRIs showing Brenner tumors prior to surgical excision. Patients (21) with ot...
journal_title:Magnetic resonance imaging
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0730-725x(98)00136-2
更新日期:1998-12-01 00:00:00
abstract::The clinical evaluation of three-dimensional time-of-flight MR angiography was prospectively performed in 16 patients with intracranial meningioma. MR angiographic techniques used in this study both with and without gadopentetate dimeglumine made it possible to demonstrate the topographic relationship between the tumo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(93)90466-q
更新日期:1993-01-01 00:00:00
abstract::The midcalf muscles of eight patients who had peripheral arterial occlusive disease were evaluated by exercise MRI before and after bypass surgery or percutaneous transluminal angioplasty. MRI showed a high intensity of these muscles, especially the posterior muscles, after exercise in all patients before intervention...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(95)00018-c
更新日期:1995-01-01 00:00:00
abstract::Non-CE MRA techniques (true steady-state free-precession, SSFP) have been used effectively for the selective visualization of the portal venous system and inferior vena cava. Budd-Chiari Syndrome (BCS) encompasses a number of conditions that cause the obstruction of the hepatic outflow tract from the small hepatic vei...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.10.006
更新日期:2017-02-01 00:00:00
abstract::With the recent development of integrated positron emission tomography-magnetic resonance imaging (PET-MRI) scanners, new possibilities for quantitative molecular imaging of cancer are realized. However, the practical advantages and potential clinical benefits of the ability to record PET and MRI data simultaneously m...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
doi:10.1016/j.mri.2012.06.001
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:Rapid regional fluctuations in GABA may result in inhomogeneous concentrations throughout the brain parenchyma. The goal of this study is to provide further insight into the natural distribution of GABA throughout the brain and thus determine if a surrogate site may be used for spectroscopy when evaluating moto...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.02.015
更新日期:2015-06-01 00:00:00
abstract::In this work an interleaved multiple-gradient-echo chemical shift imaging (IMGE-CSI) technique was designed, implemented and evaluated at 1.5 and 4T for high-resolution lipid quantification and R(2)* measurement in-vivo. The method is analogous to echo planar CSI but utilizes conventional gradient echoes, exploiting t...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(00)00165-x
更新日期:2000-09-01 00:00:00
abstract::Hippocampal metabolite concentrations were determined by localized in vivo proton magnetic resonance spectroscopy (1H MRS) in eleven patients suffering from refractory mesial temporal lobe epilepsy (MTLE), as well as in eleven age-matched healthy volunteers, and compared with patient history, postoperative outcome and...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00123-4
更新日期:1998-10-01 00:00:00
abstract::Disseminated osseous tuberculosis is a rare disease. This is a report of two cases of disseminated osseous tuberculosis imaged with MRI at 1.5-T, CT, plain radiography and bone scintigraphy. CT and plain radiography demonstrated either highly destructive or cystic lesions with sclerotic margins. Bone scintigraphy and ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(87)90384-5
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:This study aims to develop and evaluate a robust conductivity imaging method that combines total variation and wavelet regularization to enhance the accuracy of conductivity maps. THEORY AND METHODS:The proposed approach is based on a gradient-based method. The central equation is derived from Maxwell's equati...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2020.02.015
更新日期:2020-06-01 00:00:00
abstract::In vivo spin-lattice relaxation times, T1, of water and lipid protons of normal and atrophic muscles were measured, using the spatially resolved spectroscopy (SPARS) sequence, in a genetic avian model of myopathy. These T1 values were compared with those of the hypertrophic muscles. Although the water T1 values of mus...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(89)90550-x
更新日期:1989-05-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) was used to investigate the spatial distribution of cortical activation in frontal and parietal lobes during auditory and visual oddball tasks in 10 healthy subjects. The purpose of the study was to compare activation within auditory and visual modalities and identify commo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(00)00128-4
更新日期:2000-06-01 00:00:00
abstract::Within the magnetic resonance imaging (MRI) community the trend is going to higher and higher magnetic fields, ranging from 1.5 T to 7 T, corresponding to Larmor frequencies of 63.8-298 MHz. Since for high-field MRI the magnetization increases with the applied magnetic field, the signal-to-noise-ratio increases as wel...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.014
更新日期:2013-02-01 00:00:00
abstract::In this retrospective study we tested the hypothesis that the net effect of impaired electrical conduction and therefore increased heat dissipation in multiple sclerosis (MS) results in elevated lateral ventricular (LV) cerebrospinal fluid (CSF) diffusivity as a measure of brain temperature estimated in vivo using dif...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2014.11.002
更新日期:2015-04-01 00:00:00
abstract::Surface modification of liposomes containing Gd-diethylenetriaminepentaacetyl-phosphatidylethanolamine (Gd-DTPA-PE) as an amphiphilic paramagnetic label influences their contrast properties as MRI agents. Liposomes with the mean diameter ca. 220 nm and 10% mol content of Gd-DTPA-PE were modified with dextran (molecula...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)00083-f
更新日期:1995-01-01 00:00:00
abstract::Wall shear stress (WSS) is a relevant hemodynamic indicator of the local stress applied on the endothelium surface. More specifically, its spatiotemporal distribution reveals crucial in the evolution of many pathologies such as aneurysm, stenosis, and atherosclerosis. This paper introduces a new solution, called PaLMA...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2020.08.017
更新日期:2020-12-01 00:00:00
abstract::Quantifying the intracranial tissue volume changes in magnetic resonance imaging (MRI) assists specialists to analyze the effects of natural or pathological changes. Since these changes can be subtle, the accuracy of the automatic compartmentalization method is always criticized by specialists. We propose and then eva...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.11.002
更新日期:2020-01-01 00:00:00
abstract::SSFP-based fMRI techniques, known for their high specificity and low geometrical distortion, look promising for high-resolution brain mapping. Nevertheless, they suffer from lack of speed and sensitivity, leading them to be exploited mostly in high-field scanners. Radial acquisition can help with these inefficiencies ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2020.09.005
更新日期:2020-12-01 00:00:00
abstract::The most recently reported magnetic resonance first-pass myocardial perfusion studies were restricted to single slice imaging or a data analysis based on interactively placed regions of interest. This study was designed to investigate a new saturation recovery TurboFLASH sequence for multisection myocardial perfusion ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00166-0
更新日期:1999-02-01 00:00:00
abstract::Multi-contrast magnetic resonance imaging (MRI) is a useful technique to aid clinical diagnosis. This paper proposes an efficient algorithm to jointly reconstruct multiple T1/T2-weighted images of the same anatomical cross section from partially sampled k-space data. The joint reconstruction problem is formulated as m...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2014.08.025
更新日期:2014-12-01 00:00:00
abstract::Percentage of lipid content of 22 adrenal cortex lesions and their water proton longitudinal relaxation time were measured in vitro at 60 MHz. Although water relaxation times obtained on benign and malignant samples overlap each other, measurements of the percentage of lipids performed on the same tissues allow us to ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(87)90123-8
更新日期:1987-01-01 00:00:00
abstract::Recent compressed sensing techniques allow signal acquisition with less sampling than required by the Nyquist-Shannon theorem which reduces the data acquisition time in magnetic resonance imaging (MRI). However, prior knowledge becomes essential to reconstruct detailed features when the sampling rate is exceedingly lo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.10.009
更新日期:2016-02-01 00:00:00
abstract::Pulsed field gradient (PFG) nuclear magnetic resonance (NMR) and microimaging experiments have been performed to study the diffusion of liquid alkanes into a variety of semicrystalline polyethylene (PE) samples. The results highlight the importance of the crystalline phase in controlling the diffusion process in terms...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00032-0
更新日期:1998-06-01 00:00:00
abstract::The purpose of this study was to evaluate the diagnostic potential of a high-resolution magnetic resonance (MR) venography technique in patients with cerebral arteriovenous malformations (AVMs). A high-resolution 3D gradient echo sequence was used with a long echo time TE to obtain venous information down to sub-pixel...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00084-3
更新日期:1999-12-01 00:00:00
abstract::A new application of the stimulated echo pulse sequence is presented that permits the elucidation of molecular order and dynamics in a time scale between about 100 microseconds and the spin-lattice relaxation time. The technique exploits the influence of dipolar coupling on the quotient of the stimulated and primary e...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00172-5
更新日期:1996-01-01 00:00:00
abstract::Interventions for peripheral arterial disease should be designed to treat a physiological rather than an anatomic defect. Thus, for vascular surgeons, functional information about stenoses is as important as the anatomic one. In case of finding a stenosis by the use of magnetic resonance angiography, it would be a mat...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2008.01.013
更新日期:2008-10-01 00:00:00