Abstract:
:We assessed the magnetic resonance (MR) imaging characteristics of two categories of epileptogenic substrates, neoplasms, and vascular malformations, to determine MR sensitivity and typical imaging features. A blinded retrospective analysis was performed on MR scans from 41 patients who had a neoplasm or vascular malformation surgically resected as treatment for medically refractory epilepsy. Abnormalities were assessed for sensitivity of MR detection, prediction of pathologic category, location, calvarial remodelling, signal intensity, and effect on adjacent tissue. Pathologic findings consisted of 33 tumors and 8 vascular malformations. We correctly localized 100% of the 41 lesions and predicted the correct pathologic category for 95% of these lesions. Neoplastic and vascular lesions (NVLs) associated with epilepsy had certain characteristic features. The temporal lobe was the most common site for NVL, involved in 68%. NVL were located in the brain periphery in 85% and remodelled the calvarium in 32%. NVL were associated with mass effect in 61%, volume loss in 1%, and no effect on adjacent tissue in 37%. NVL associated with epilepsy can be detected with high sensitivity using MR imaging. The temporal lobe location, cortical involvement, and calvarial remodelling are findings typical of NVL. MR characteristics can successfully predict the pathologic substrate of these lesions.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Bronen RA,Fulbright RK,Spencer DD,Spencer SS,Kim JH,Lange RCdoi
10.1016/0730-725x(95)02026-psubject
Has Abstractpub_date
1995-01-01 00:00:00pages
1153-62issue
8eissn
0730-725Xissn
1873-5894pii
0730-725X(95)02026-Pjournal_volume
13pub_type
杂志文章abstract::Positive contrast imaging methods produce enhanced signal at large magnetic field gradient in magnetic resonance imaging. Several postprocessing algorithms, such as susceptibility gradient mapping and phase gradient mapping methods, have been applied for positive contrast generation to detect the cells targeted by sup...
journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
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journal_title:Magnetic resonance imaging
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更新日期:2010-10-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)00093-i
更新日期:1995-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00024-0
更新日期:1997-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00176-3
更新日期:1999-04-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(02)00608-2
更新日期:2002-12-01 00:00:00
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journal_title:Magnetic resonance imaging
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更新日期:2013-11-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2009.01.002
更新日期:2009-07-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.05.002
更新日期:2016-10-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00013-2
更新日期:1999-07-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2014.08.019
更新日期:2015-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(92)90371-6
更新日期:1992-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)90089-a
更新日期:1994-01-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.05.012
更新日期:2016-10-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2010.03.009
更新日期:2010-06-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
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更新日期:2011-04-01 00:00:00
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更新日期:2007-07-01 00:00:00
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更新日期:2018-09-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00152-x
更新日期:1996-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0730-725x(97)82763-4
更新日期:1997-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1988-07-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2011.09.017
更新日期:2012-02-01 00:00:00
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journal_title:Magnetic resonance imaging
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doi:10.1016/j.mri.2018.04.013
更新日期:2018-09-01 00:00:00
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(85)90012-8
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2009.12.016
更新日期:2010-10-01 00:00:00
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pub_type: 杂志文章,多中心研究
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