Abstract:
:Recent advances in angioplasty have involved the application of polymer coatings to stent surfaces for purposes of drug delivery. Given the high levels of deformation developed in the plastic hinge of a stent during deployment, the achievement of an intact bond between the coating and the stent presents a significant mechanical challenge. Problems with coating delamination have been reported in recent experimental studies. In this paper, a cohesive zone model of the stent-coating interface is implemented in order to investigate coating debonding during stent deployment. Simulations reveal that coatings debond from the stent surface in tensile regions of the plastic hinge during deployment. The critical parameters governing the initiation of delamination include the coating thickness and stiffness, the interface strength between the coating and stent surface, and the curvature of the plastic hinge. The coating is also computed to debond from the stent surface in compressive regions of the plastic hinge by a buckling mechanism. Computed patterns of coating delamination correlate very closely with experimental images. This study provides insight into the critical factors governing coating delamination during stent deployment and offers a predictive framework that can be used to improve the design of coated stents.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Hopkins CG,McHugh PE,McGarry JPdoi
10.1007/s10439-010-9972-ysubject
Has Abstractpub_date
2010-07-01 00:00:00pages
2263-73issue
7eissn
0090-6964issn
1573-9686journal_volume
38pub_type
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