Abstract:
:Natural products can exhibit many beneficial effects on human health. As far as cancer is concerned, naturally occurring compounds have been reported to prevent tumorigenesis and also to suppress the growth of established tumors. As cancer cells have evolved multiple mechanisms to resist the induction of programmed cell death (apoptosis), the modulation of apoptosis signaling pathways by natural compounds has been demonstrated to constitute a key event in these antitumor activities. This review presents some examples of how apoptosis pathways are targeted by selected naturally occurring agents and how these events can be exploited for cancer therapy.
journal_name
Planta Medjournal_title
Planta medicaauthors
Fulda Sdoi
10.1055/s-0030-1249961subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1075-9issue
11eissn
0032-0943issn
1439-0221journal_volume
76pub_type
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