Synthetic peptides derived from IRBP induce EAU and EAP in Lewis rats.

abstract：PURPOSE:The high prevalence of positive family history of keratoconus (KC) in KC patients is well-known. However, the results regarding the association between family history of KC and disease severity are controversial. The aim of this study was to evaluate the possible association between family history and severity ...

journal_title：Current eye research

authors： Naderan M,Rajabi MT,Zarrinbakhsh P,Naderan M,Bakhshi A

更新日期：2016-11-01 00:00:00

abstract：:Goggles that degrade the retinal image produce axial enlargement of the ocular globe and large myopic refractive errors. Many authors have assumed that visual image degradation itself leads to myopia. Hodos and co-authors have shown, however, that goggled eyes in chicks are considerably warmer than normal. Such temper...

journal_title：Current eye research

authors： Shih YF,Fitzgerald ME,Norton TT,Gamlin PD,Hodos W,Reiner A

更新日期：1993-03-01 00:00:00

abstract：:The management of opportunistic infections is a significant problem in acquired immunodeficiency syndrome (AIDS) and the development of more effective chemotherapeutic agents is needed. We present the ocular manifestations of an AIDS-like disease in rhesus monkeys experimentally infected with simian immunodeficiency v...

journal_title：Current eye research

authors： Conway MD,Didier P,Fairburn B,Soike KF,Martin L,Murphey-Corb M,Meiners N,Insler MS

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Aqueous extract of Pleurotus tuberregium (PT) has been shown to reduce intraocular pressure (IOP) but the underlying mechanism has not been explained. PURPOSE:To investigate the effect of PT on the bovine iris in vitro in comparison with acetylcholine (ACh). METHOD:Strips of the iris were mounted in 10 ml ...

journal_title：Current eye research

authors： Akinlabi GA,Asowata OE,Ozolua RI,Akpaja OO,Iyawe V

更新日期：2013-03-01 00:00:00

abstract：:To enhance efforts directed at unraveling the role and mechanisms of leukocytes in mediating injury to corneal epithelium, an isolated bovine corneal cup was developed and evaluated. Bovine peripheral leukocytes and lysates were added to the corneal epithelial surface of isolated cornea for various periods after which...

journal_title：Current eye research

authors： Elgebaly SA,Gillies C,Forouhar F,Hashem M,Baddour M,O'Rourke J,Kreutzer DL

更新日期：1985-01-01 00:00:00

abstract：AIM:To compare patient satisfaction and experience after external dacryocystorhinostomy (EX-DCR) versus transcanalicular DCR (TC-DCR) with a diode laser and to evaluate the change in quality of life following simultaneous bilateral DCR. METHODS:Prospective evaluation of 38 eyes of 19 patients with bilateral nasolacrim...

journal_title：Current eye research

authors： Yeniad B,Uludag G,Kozer-Bilgin L

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:To analyze the effect of diamidines (hexamidine-diisethionat (HD), propamidin-isethionate (PD), dibromopropamidine-diisethionat (DD)), and biguanides (polyhexamethylen biguanid (PHMB), chlorhexidine (CH)) on human corneal epithelial cell, keratocyte and endothelial cell viability, proliferation, and migration, ...

journal_title：Current eye research

authors： Shi L,Stachon T,Seitz B,Wagenpfeil S,Langenbucher A,Szentmáry N

更新日期：2018-06-01 00:00:00

abstract：:A bovine lens "native" plasma membrane fraction containing its full compliment of extrinsic proteins was prepared by sucrose density centrifugation of the water insoluble fraction. The major membrane fraction was found at the 25/45% sucrose interface. This fraction contained 73% of the total water insoluble phospholip...

journal_title：Current eye research

authors： Fleschner CR,Cenedella RJ

更新日期：1992-08-01 00:00:00

abstract：PURPOSE:To investigate the association of nailfold capillaroscopy, heart rate variability (HRV), and clinical characteristics of glaucoma with the plasma matrix metalloproteinase-9 (MMP-9) level in normal-tension glaucoma (NTG). MATERIALS AND METHODS:We conducted a prospective, cross-sectional study on 25 patients wit...

journal_title：Current eye research

authors： Lee NY,Park HY,Park SH,Park CK

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To investigate the efficacy of intravitreal piperacillin/tazobactam (250 microg/0.1 ml) in the treatment of experimental Pseudomonas aeruginosa endophthalmitis in rabbits. MATERIALS AND METHODS:Twenty New Zealand White albino rabbits were used in this study. The rabbits were divided into two groups (10 rabbits...

journal_title：Current eye research

authors： Ozkiris A,Evereklioglu C,Esel D,Akgün H,Göktas S,Erkiliç K

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:To validate the more easily applicable "flush" tear collection technique as a viable alternative to basal and reflex tear collection. MATERIALS AND METHODS:Total protein content (TPC) and immunoglobulin A (IgA) concentrations were determined in the basal, reflex, and flush tears of 16 healthy non-contact lens ...

journal_title：Current eye research

authors： Markoulli M,Papas E,Petznick A,Holden B

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To evaluate the anatomical correlation between fellow eyes for bilateral second-line anti-VEGF treatment in eyes with bilateral diabetic macular edema (DME) with incomplete response to first-line bevacizumab therapy. METHODS:Seventy-four eyes (n = 37 patients) with bilateral-DME having incomplete response to f...

journal_title：Current eye research

authors： Tiosano L,Ayalon A,Banin E,Averbukh E,Jaouni T,Chowers I

更新日期：2020-08-30 00:00:00

abstract：:Due to the multiple barriers imposed by the eye against the penetration of drugs, the ocular delivery and targeting are considered difficult to achieve. A major challenge in ocular drug therapy is to improve the poor bioavailability of topically applied ophthalmic drugs by overcoming the severe constraints imposed by ...

journal_title：Current eye research

authors： Souto EB,Doktorovova S,Gonzalez-Mira E,Egea MA,Garcia ML

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:In keratoconus corneas, it has been shown that levels of degradative enzymes and transcription factor Sp1 are elevated and those of inhibitors are reduced, especially in the epithelial layer. This study is to determine whether the biochemical abnormalities identified in corneas also exist in conjunctival tissue...

journal_title：Current eye research

authors： Maruyama I,Zhou L,Sugar J,Yue BY

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:Phagocytosis of rod outer segments (ROS) is an important function of retinal pigment epithelial (RPE) cells. Since the details of the process are not fully known, we studied effects of cytokines produced by RPE and photoreceptor cells on phagocytosis of ROS by rat RPE cells. METHODS:RPE cells were isolated and...

journal_title：Current eye research

authors： Hayashi A,Nakae K,Naka H,Ohji M,Tano Y

更新日期：1996-05-01 00:00:00

abstract：:A prototype automated flicker perimeter was used to investigate flicker luminance thresholds in glaucoma patients (n = 11), ocular hypertensives (high risk n = 10, low and intermediate risk n = 21) and normal controls (n = 10). Differential light sensitivity was measured for one eye of each subject using a flickering ...

journal_title：Current eye research

authors： Austin MW,O'Brien CJ,Wishart PK

更新日期：1994-10-01 00:00:00

abstract：:Arachidonic acid metabolism via the cyclooxygenase pathway and the effects of aspirin and indomethacin were studied in whole retinas of rats with streptozotocin-induced diabetes. Diabetes was induced by intravenous injection of streptozotocin (60 mg/kg) and the animals were examined 5-6 weeks later. Whole retinas of n...

journal_title：Current eye research

authors： Naveh-Floman N,Weissman C,Belkin M

更新日期：1984-09-01 00:00:00

abstract：PURPOSE:The aim of the present study was to calculate the diameter of the central retinal artery from results as obtained with non-invasive techniques in healthy young subjects. METHODS:Twenty-four healthy male subjects participated in this study. Total retinal blood flow was calculated from combined bi-directional la...

journal_title：Current eye research

authors： Dorner GT,Polska E,Garhöfer G,Zawinka C,Frank B,Schmetterer L

更新日期：2002-12-01 00:00:00

abstract：AIM OF THE STUDY:The similarity of many benign intrabulbar lesions to a malignant tumor requires detailed differential diagnostics. However, none of the known methods can be used as the only one to determine the type of lesions. The aim of this study was to determine color Doppler imaging (CDI) markers characteristic o...

journal_title：Current eye research

authors： Modrzejewska M,Wiącek MP

更新日期：2017-11-01 00:00:00

abstract：:High pressure liquid chromatography was used to measure alpha-tocopherol in the retinas of rats reared in a cyclic light or dark environment. These measurements were performed on extracts of whole retinas during the developmental period, 18-60 days, and on isolated ROS from adult animals. Similar alpha-tocopherol dete...

journal_title：Current eye research

authors： Hunt DF,Organisciak DT,Wang HM,Wu RL

更新日期：1984-11-01 00:00:00

abstract：PURPOSE:To determine the cellular mechanisms involved in the hypoxia-induced alteration of the retinal pigment epithelium (RPE) potentials and the light-evoked responses of the RPE in chicks. In addition, to determine the mechanisms involved in the recovery of the RPE during the post-hypoxic period. METHODS:In vitro p...

journal_title：Current eye research

authors： Nakazaki S,Nao-i N,Sawada A

更新日期：1998-04-01 00:00:00

abstract：PURPOSE:To detect the immunohistochemical changes in the main lacrimal glands of patients suffering from chronic ocular sequelae of Stevens-Johnson syndrome (SJS). METHODS:Histological sections of biopsies from the lacrimal gland of three chronic SJS patients (mean age, 33 years; 2 males) with severe dry eye disease (...

journal_title：Current eye research

authors： Singh S,Ali MJ,Mittal V,Brabletz S,Paulsen F

更新日期：2020-10-18 00:00:00

abstract：OBJECTIVE:Children with chronic kidney diseases (CKD) are at risk for neurological diseases at early adulthood. Spectral-domain optical coherence tomography (SD-OCT) of the retina is especially suitable for determination of intraretinal layer thickness. We wonder whether retinal thinning is already present in pediatric...

journal_title：Current eye research

authors： Prakasam RK,Götze A,von Keyserlingk S,Jünemann A,Röhlig M,Stachs O,Fischer DC

更新日期：2019-02-01 00:00:00

abstract：:Purpose: To investigate the cytotoxic effects of fresh black carbon (FBC) particles and ozone-oxidized BC (OBC) particles on human corneal epithelial cells (HCECs), and the role of the NLRP3 inflammasome signal pathway in the process.Methods: HCECs were treated with different doses of FBC and OBC particles, the cell i...

journal_title：Current eye research

authors： Long Q,Huang Y,Shang J,Liu Y,Chen C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To determine by immunohistochemistry the distribution of different nitric oxide synthases (NOS) isoforms in the porcine eye. METHODS:By light microscopy (immunofluorescence), porcine ocular tissues were investigated using monoclonal antibodies against neuronal NOS (nNOS; NOS I), endothelial NOS (ecNOS; NOS III...

journal_title：Current eye research

authors： Meyer P,Champion C,Schlötzer-Schrehardt U,Flammer J,Haefliger IO

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:Oxidative stress is considered a major factor in the deterioration of retinal pigment epithelium (RPE) cells in dry age-related macular degeneration (AMD). The MAPK ERK1/2 can be activated by oxidative stress, may exert both pro- and anti-apoptotic functions, and has recently been proposed as a major factor in ...

journal_title：Current eye research

authors： Koinzer S,Reinecke K,Herdegen T,Roider J,Klettner A

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To determine the effects of a subconjunctival injection of mitomycin-C (MMC) on iridial circulation in rabbits. METHODS:Dutch rabbits anesthetized with pentobarbital received a 0.2-ml subconjunctival injection of 0.4 mg/ml or 0.1 mg/ml MMC; the contralateral eye received 0.2 ml physiological saline. Intraocula...

journal_title：Current eye research

authors： Tomidokoro A,Araie M,Tamaki Y,Muta K

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Interleukin-6 (IL-6) is produced by a variety of cells involved in inflammation and acts as local intensification signals in pathological processes associated with chronic eye inflammation. This meta-analysis was performed to provide a better understanding of the relationship between IL-6 and diabetic retino...

journal_title：Current eye research

authors： Yao Y,Li R,Du J,Long L,Li X,Luo N

更新日期：2019-05-01 00:00:00

abstract：:A model system for retinal adhesion, consisting of interacting bovine pigment, epithelium (PE) cells and photoreceptor outer segments, was utilized to examine any adhesive role of the interphotoreceptor matrix. PE cells were dissociated by trypsin treatment of the eyecup, and were allowed to replenish their surface pr...

journal_title：Current eye research

authors： Adler AJ,Klucznik KM

更新日期：1981-01-01 00:00:00

abstract：:Specimens of a cornea, conjunctiva and iris were removed at the time of penetrating keratoplasty in a case of nephropathic cystinosis. Immunohistochemical studies revealed the presence of class II antigens on the stromal keratocytes of the cornea and the vascular endothelial cells, pericytes and fibroblasts of the con...

journal_title：Current eye research

authors： Kaiser-Kupfer MI,Chan CC,Rodrigues M,Datiles MB,Gahl WA

更新日期：1987-04-01 00:00:00