The association between TNF-alpha promoter polymorphisms and ankylosing spondylitis: a meta-analysis.

abstract：:Hundreds of randomized controlled trials (RCTs) on tripterygium glycosides tablet (TGT) in the treatment of ankylosing spondylitis (AS) have been published, but the therapeutic effects have never been systematically reviewed yet. The aim of this meta-analysis was to evaluate the efficacy of TGT on AS based on RCTs. Pu...

journal_title：Clinical rheumatology

authors： Li H,Guo F,Luo YC,Zhu JP,Wang JL

更新日期：2015-11-01 00:00:00

abstract：:This study aims to develop a sandwich ELISA system for the measurement of soluble folate receptor β (sFRβ) and evaluate whether base line levels of serum sFRβ are a biomarker for the activity of RA synovitis and the response to anti-TNF agents. Serum sFRβ from normal controls (41 samples), patients with OA (29 samples...

journal_title：Clinical rheumatology

authors： Otsubo H,Tsuneyoshi Y,Nakamura T,Matsuda T,Komiya S,Matsuyama T

更新日期：2018-11-01 00:00:00

abstract：:Anti-nucleosome antibodies, which recognise conformational epitopes consisting of histone and DNA in chromatin, have been described in autoimmune diseases. In this study, an attempt was made to isolate anti-nucleosome antibodies from the anti-DNA-depleted plasma IgG of two lupus patients either with or without nephrit...

journal_title：Clinical rheumatology

authors： Suenaga R,Mitamura K,Abdou NI

更新日期：1998-01-01 00:00:00

abstract：:Spontaneous fractures of the sternum are rare but worth knowing as they may simulate acute cardiac and pulmonary emergencies. A case of an insufficiency sternal fracture mimicking myocardial infarction and subsequent anginal pain is presented. The risk factors of this condition, its clinical features and the diagnosti...

journal_title：Clinical rheumatology

authors： Schapira D,Nachtigal A,Scharf Y

更新日期：1995-07-01 00:00:00

abstract：:Pulse therapy is one of the most well-known methods used in the treatment of juvenile rheumatoid arthritis. This study assessed the outcome of methylprednisolone pulse therapy, its rate of efficacy, and its associated complications in patients with juvenile rheumatoid arthritis (JRA). This cross-sectional study was pe...

journal_title：Clinical rheumatology

authors： Aghighi Y,Attarod L,Javanmard M

更新日期：2008-11-01 00:00:00

abstract：:Extensive subcutaneous and muscular calcification developed in a patient having adult-onset dermatopolymyositis (DM-PM) with an 'overlap' connective tissue disease. We wish to emphasize the rarity of calcification in adult onset DM-PM, which is contrary to the generally held impression. ...

journal_title：Clinical rheumatology

authors： Cohen MG,Nash P,Webb J

更新日期：1986-12-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a progressive inflammatory disease. Although the etiology and pathogenesis of RA are not known well, genetic and environmental factors are proposed to initiate an autoimmune process. We aimed to investigate mRNA expression levels of Toll-like receptor-2 (TLR-2), TLR-4, and interleukin-6 (I...

journal_title：Clinical rheumatology

authors： Eser B,Sahin N

更新日期：2016-11-01 00:00:00

abstract：:The aims of the study were to assess the health-related quality of life (QOL) in patients with Takayasu's arteritis (TA) by two different generic QOL instruments and to compare the results with those patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and healthy controls (HC). A cross-sectional stud...

journal_title：Clinical rheumatology

authors： Akar S,Can G,Binicier O,Aksu K,Akinci B,Solmaz D,Birlik M,Keser G,Akkoc N,Onen F

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy and safety of tocilizumab with those of abatacept in patients with active rheumatoid arthritis not responding to anti-tumor necrosis factor therapy. METHODS:A prospective, open-label study was carried out on adult females with moderate-to-severe rheumatoid arthritis. Patients were ra...

journal_title：Clinical rheumatology

authors： Elmedany SH,Mohamed AE,Galil SMA

更新日期：2019-08-01 00:00:00

abstract：:A correlation study was performed on the degree of muscle weakness in 36 patients with dermatomyositis and 69 with polymyositis in relation to muscle biopsy findings, electromyography (EMG) abnormalities, and serum concentrations of creatine kinase (CK), aspartate aminotransferase (AST) and alanine aminotransferase (A...

journal_title：Clinical rheumatology

authors： Tymms KE,Beller EM,Webb J,Schrieber L,Buchanan WW

更新日期：1990-12-01 00:00:00

abstract：:Acute phase proteins, synovial fluid (SF) cellular infiltrates, pro-inflammatory (TNF-alpha, IL-1alpha, IL-6) and Th1 (IL-2) and Th2 (IL-4) derived cytokine levels both in plasma and SF were examined in pauciarticular and polyarticular juvenile chronic arthritis (JCA) patients during the active (n = 22) and inactive (...

journal_title：Clinical rheumatology

authors： Kutukculer N,Caglayan S,Aydogdu F

更新日期：1998-01-01 00:00:00

abstract：:We investigated the association between smoking and the disease activity, functional ability, physical mobility, and systemic inflammation in Chinese ankylosing spondylitis (AS) patients. Seventy five male Chinese AS patients in Taiwan were enrolled in the cross-sectional study. These patients fulfilled the 1984 modif...

journal_title：Clinical rheumatology

authors： Chen CH,Chen HA,Lu CL,Liao HT,Liu CH,Tsai CY,Chou CT

更新日期：2013-05-01 00:00:00

abstract：:The aim of this study is to compare the three classification criteria for rheumatoid arthritis (RA) in a large cohort of early arthritis patients. Patients who had at least one clinically swollen joint with disease duration no more than 1 year and age more than 18 years were enrolled. The clinical and laboratory param...

journal_title：Clinical rheumatology

authors： Ye H,Su Y,Li R,Zhao J,Liu X,Mei Y,Zhang Z,Guo J,Bi L,Liu X,Wang G,Liu J,Leng X,Gu F,Sun L,Zou Q,Fang Y,Jiang Q,Li Z

更新日期：2016-10-01 00:00:00

abstract：:The aim of the study was to demonstrate the effectiveness of sulphurous water in patients with osteoarthritis of the hand. Forty-seven patients with osteoarthritis of the hand were enrolled into the double-blind, randomized, controlled study, satisfying ACR criteria. One group of the patients (n = 24) received balneot...

journal_title：Clinical rheumatology

authors： Kovács C,Pecze M,Tihanyi Á,Kovács L,Balogh S,Bender T

更新日期：2012-10-01 00:00:00

abstract：:Adiponectin is a hormone released by adipose tissue with antidiabetic, antiatherogenic, and anti-inflammatory properties. The present observational study focused on the relation between serum adiponectin level and the disease severity of established rheumatoid arthritis (RA). Ninety patients with more than 5-year diag...

journal_title：Clinical rheumatology

authors： Ebina K,Fukuhara A,Ando W,Hirao M,Koga T,Oshima K,Matsuda M,Maeda K,Nakamura T,Ochi T,Shimomura I,Yoshikawa H,Hashimoto J

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:Immunoglobulin A vasculitis (IgAV) is the most common form of childhood systemic vasculitis. It is mostly self-limiting and characterized by skin, joint, gastrointestinal tract, and kidney involvement. Microribonucleic acids (miRNAs) are 18-25 base-long non-coding RNA group acting on gene expression. They ...

journal_title：Clinical rheumatology

authors： Cebi AH,Demir F,Ikbal M,Kalyoncu M

更新日期：2020-10-10 00:00:00

abstract：:We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period. The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoprol...

journal_title：Clinical rheumatology

authors： Taillan B,Garnier G,Castanet J,Ferrari E,Pesce A,Dujardin P

更新日期：1993-03-01 00:00:00

abstract：:HLA-II molecules are critical in triggering human immune response, especially in activating CD4+ T cells. HLA-DP, belonging to HLA-II molecules, draws increasing attention for its role in presentation of viral antigen and autoantigen to T cells. Researches reported single nucleotide polymorphism (SNP) of HLA-DP associ...

journal_title：Clinical rheumatology

authors： Huang Z,Niu Q,Yang B,Zhang J,Yang M,Xu H,Cai B,Hu J,Wu Y,Wang L

更新日期：2018-07-01 00:00:00

abstract：:Kidney involvement in immuno-mediated diseases is a life threatening complication to be early detected. Glomerulo-tubular functional indices, kidney-released enzymes and metabolic profiles were assessed in 21 patients with systemic lupus erythematosus, progressive systemic sclerosis and mixed cryoglobulinaemia, withou...

journal_title：Clinical rheumatology

authors： Matteucci E,Migliorini P,Bertoni C,Dolcher MP,Marchini B,Giampietro O

更新日期：1996-01-01 00:00:00

abstract：:The relationship between ankylosing spondylitis and the recently proposed entity called axial spondyloarthritis with its radiographic and non-radiographic forms that have been defined by the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial spondyloarthritis (axSpA), is currently being de...

journal_title：Clinical rheumatology

authors： Akkoc N,Khan MA

更新日期：2016-06-01 00:00:00

abstract：:Hydroxyapatite (HA) crystal deposition disease is a common cause of acute inflammatory articular or periarticular pain. Here we report a patient with an acute hip arthritis due to HA crystal deposition of the round ligament. Therefore, HA crystal deposition in periarticular tendons and ligaments of the hip should be a...

journal_title：Clinical rheumatology

authors： Arlet JB,André H,Mutschler C,Dupeux S,Pouchot J

更新日期：2009-04-01 00:00:00

abstract：:The aim of the study was to investigate the long-term outcome of non-specific seronegative oligoarthritis in adults. The study included 64 adult patients with recent (<6 months) seronegative oligoarthritis (rheumatoid factor negative, number of swollen joints 1-4 during the first 6 months). Follow-up examinations were...

journal_title：Clinical rheumatology

authors： Jäntti JK,Kaarela K,Lehtinen KE

更新日期：2002-09-01 00:00:00

abstract：:Cardiovascular disease is a major health care problem and the most common cause of death among individuals from developed nations. Our understanding of atherosclerosis has evolved from a passive process resulting in narrowing of the lumen and consequent myocardial ischemia to a dynamic process that involves inflammati...

journal_title：Clinical rheumatology

authors： Chung CP,Avalos I,Raggi P,Stein CM

更新日期：2007-08-01 00:00:00

abstract：:The objective of this study was to characterise the peripheral arthritis of spondyloarthritis (pSpA) excluding psoriatic-, inflammatory enteropathy-related, post-infectious reactive-SpA and arthritis associated with axial SpA/ankylosing spondylitis (axSpA/AS). Patients presenting with the clinical features of the broa...

journal_title：Clinical rheumatology

authors： Malaviya AN,Agrawal N,Patil NS

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to investigate the association between the polymorphism of transporters associated with antigen processing ( TAP1/TAP2) genes and rheumatoid arthritis in Chinese patients. A total of 100 RA patients and 99 healthy control subjects were enrolled. Analyses with polymerase chain reaction (PCR) b...

journal_title：Clinical rheumatology

authors： Yu MC,Huang CM,Wu MC,Wu JY,Tsai FJ

更新日期：2004-02-01 00:00:00

abstract：:We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine sampl...

journal_title：Clinical rheumatology

authors： Otukesh H,Chalian M,Hoseini R,Chalian H,Hooman N,Bedayat A,Yazdi RS,Sabaghi S,Mahdavi S

更新日期：2007-12-01 00:00:00

abstract：:To estimate the mortality and describe the causes of death in a large multicenter cohort of hospitalized patients with SLE in China. This was a retrospective study of a nationwide SLE cohort (10 centers, 29,510 hospitalized patients) from 2005 to 2014 in China. Standardized mortality ratios (SMRs) were calculated for ...

journal_title：Clinical rheumatology

authors： Wu XY,Yang M,Xie YS,Xiao WG,Lin J,Zhou B,Guan X,Luo CN,Che N,Liu XZ,Wang C,Teng JL,Cheng XB,Ye JN,Su YT,Shi H,Yin YF,Liu MR,Sun Y,Hu QY,Zhou ZC,Chi HH,Liu Y,Zhang X,Chen JW,Zhang MJ,Zhao DB,Yang CD,

更新日期：2019-01-01 00:00:00

abstract：:Systemic Sclerosis (SSc; scleroderma) is associated with several immunological abnormalities, including altered proportion between lymphocyte subsets. Peripheral blood lymphocyte subsets from 25 patients with SSc were studied by two-colour flow cytometry using monoclonal antibodies against CD45RA and CD29 markers, whi...

journal_title：Clinical rheumatology

authors： Gorla R,Airò P,Malagoli A,Carella G,Prati E,Brugnoni D,Franceschini F,Cattaneo R

更新日期：1994-03-01 00:00:00

abstract：:The idiopathic inflammatory myopathies (IIM) constitute a subset of autoimmune conditions primarily affecting muscle, along with many extra-muscular manifestations. Proximal muscle weakness is the dominant symptom in the IIM. In addition, many patients will have cutaneous manifestations, pulmonary manifestations, and ...

journal_title：Clinical rheumatology

authors： Jones J,Wortmann R

更新日期：2015-05-01 00:00:00

abstract：:To characterize the distinctive chest high-resolution computerized tomography (HRCT) features and clinical manifestations of primary Sjögren syndrome (pSS)-related interstitial lung disease (ILD). The demographic data, clinical manifestations, and laboratory and radiological findings of 527 pSS patients were retrospec...

journal_title：Clinical rheumatology

authors： Dong X,Zhou J,Guo X,Li Y,Xu Y,Fu Q,Lu Y,Zheng Y

更新日期：2018-11-01 00:00:00