Abstract：
:Adiponectin is a hormone released by adipose tissue with antidiabetic, antiatherogenic, and anti-inflammatory properties. The present observational study focused on the relation between serum adiponectin level and the disease severity of established rheumatoid arthritis (RA). Ninety patients with more than 5-year diagnosis of RA and 42 age- and BMI-matched control were enrolled. The severity of RA was evaluated according to the number of destructed joints of overall 68 joints on plain radiographs (37 patients had mild RA and 53 had severe RA). Serum adiponectin level was significantly higher in the severe RA group (17.7+/-6.7 microg/ml) than in the control (9.1+/-3.8 microg/ml) and mild RA groups (13.9+/-6.5 microg/ml) (control vs. mild RA group, P<0.001; mild RA vs. severe RA group, P<0.01). These results suggest that increased number of joint destruction is associated with hyperadiponectinemia in established RA patients.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Ebina K,Fukuhara A,Ando W,Hirao M,Koga T,Oshima K,Matsuda M,Maeda K,Nakamura T,Ochi T,Shimomura I,Yoshikawa H,Hashimoto Jdoi
10.1007/s10067-008-1074-ysubject
Has Abstractpub_date
2009-04-01 00:00:00pages
445-51issue
4eissn
0770-3198issn
1434-9949journal_volume
28pub_type
杂志文章abstract：:The sternocostoclavicular (SCC) region is subject to the same diseases that occur in joints, with congenital and developmental anomalies, inflammatory and infectious diseases, soft tissue and bone tumors as well as the seronegative spondyloarthropathies, including ankylosing spondylitis, reactive arthritis, enteropath...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-008-0905-1
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to analyze the prevalence of myositis-specific autoantibodies (MSAs) and to elucidate their associations with clinical features in Chinese patients with polymyositis (PM) and dermatomyositis (DM). METHODS:Twelve subsets of MSAs including anti-Mi-2, anti-TIF1-γ, anti-MDA5, anti-NXP2,...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04503-7
更新日期：2019-08-01 00:00:00
abstract：:The objective of the study was to determine clinical factors associated with activity limitation and predictors of a change in activity limitation after 1 year in people with gout. Two hundred ninety-five participants with gout (disease duration < 10 years) attended a baseline assessment which included medical and dis...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4110-6
更新日期：2018-08-01 00:00:00
abstract：:Coexistence of rheumatoid arthritis and gout is considered to be unusual. The current study was designed as a population-based cross-sectional study, utilizing the medical database of Clalit Health Services, the largest healthcare provider organization in Israel. Data of adult patients who were previously diagnosed wi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-016-3477-5
更新日期：2017-03-01 00:00:00
abstract：:We described a 21-year-old woman with a diagnosis of Sjögren syndrome that came for consultation with a localized mass over her left arm of fast growth. Lab results were normal; a Doppler ultrasound showed the presence of partial thrombosis in the left axillary vein; a magnetic resonance imaging showed edema on the bi...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-3133-5
更新日期：2016-04-01 00:00:00
abstract：:Gastrointestinal tract (GIT) is the most common organ system involved in systemic sclerosis (SSc). GIT involvement is mainly attributed to GIT dismobility and wide mouth diverticular. GIT involvement in SSc can be also severely debilitating and even life threatening. To our knowledge, the presence of gastrointestinal ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0264-8
更新日期：2007-06-01 00:00:00
abstract：INTRODUCTION:Alkaptonuria (AKU) is a rare metabolic disease. The global incidence is 1:100,000 to 1:250,000. However, identification of a founder mutation in a gypsy population from India prompted us to study the prevalence of AKU in this population and to do molecular typing in referred cases of AKU from the rest of I...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05020-8
更新日期：2020-09-01 00:00:00
abstract：:Pauci-immune necrotizing glomerulonephritis is a form of a rapidly progressive glomerulonephritis that is associated with the anti-neutrophil cytoplasmic antibodies (ANCA). ANCA-associated pauci-immune glomerulonephritis may be secondary to rheumatic diseases. We report on a patient with limited cutaneous systemic scl...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-012-2010-8
更新日期：2012-08-01 00:00:00
abstract：:Multilevel studies have gained importance for highlighting social inequalities in health. These associations have been reported previously in diseases such as arthritis and chronic pain. We conducted a cross-sectional study using multilevel analysis to identify individual and contextual factors associated with the var...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2776-y
更新日期：2016-01-01 00:00:00
abstract：:The aim of this study was to describe a single-center experience in the treatment and follow-up of cystoid macular edema patients. Clinical records of all patients with cystoid macular edema followed up in the Rheumatologic and Ophthalmological Unit of our center between 1993 and 2013 were retrospectively evaluated. T...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2694-z
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION:Immunoglobulin A vasculitis (IgAV) is the most common form of childhood systemic vasculitis. It is mostly self-limiting and characterized by skin, joint, gastrointestinal tract, and kidney involvement. Microribonucleic acids (miRNAs) are 18-25 base-long non-coding RNA group acting on gene expression. They ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05441-5
更新日期：2020-10-10 00:00:00
abstract：:The aim of this study was to evaluate if pulsed electromagnetic field therapy (PEMF) has additional effect on the classical physical treatment of knee osteoarthritis (OA) composed of hot pack, therapeutic ultrasound, and terminal isometric exercises. Forty patients (29 women and 11 men), ages 44 to 78 (mean age was 61...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-010-1453-z
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:To investigate the clinical characteristics, laboratory features, and treatment outcomes of Thai patients compared between those with necrotizing autoimmune myopathy (NAM) and those with other idiopathic inflammatory myopathies (IIMs) or non-NAM. METHODS:This multicenter case-control study included patients ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10067-019-04756-2
更新日期：2019-12-01 00:00:00
abstract：:Electrocardiographic (ECG) and echocardiographic examinations and 24-h ECG Holter monitoring were carried out in 100 patients (age < 65 years) with rheumatoid arthritis (RA) of stages II-IV according to Steinbrocker's criteria. One hundred patients with osteoarthrosis, spondyloarthrosis and painful shoulder matched fo...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF01450894
更新日期：1998-01-01 00:00:00
abstract：:Little data exists from the developing world on pregnancy in systemic lupus erythematosus (SLE). A 10-year review of pregnancies in lupus patients was conducted at a tertiary hospital in a developing country. Forty-seven pregnancies in 31 patients were identified. Eleven (23%) booked after 20 weeks gestation. There we...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0749-0
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVES:To compare the efficacy and safety of tocilizumab with those of abatacept in patients with active rheumatoid arthritis not responding to anti-tumor necrosis factor therapy. METHODS:A prospective, open-label study was carried out on adult females with moderate-to-severe rheumatoid arthritis. Patients were ra...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-019-04508-2
更新日期：2019-08-01 00:00:00
abstract：:Susceptibility to systemic lupus erythematosus (SLE) is associated with genetic, hormonal, immunological, and environmental factors. Many genes have been related with the appearance of SLE, including several loci that code different complement components and their receptors. Some genetic deficiencies of complement mol...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-008-0838-8
更新日期：2008-04-01 00:00:00
abstract：:We describe the case of a patient with anticentriole antibody-positive scleroderma spectrum disorder (SSD) who developed pulmonary hypertension. A 54-year-old woman had noticed Raynaud's phenomenon and digital ulcers during the winter for the past 10 years. Although sclerodactyly was not present, digital ulcers, swell...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-004-0871-1
更新日期：2004-06-01 00:00:00
abstract：:Bacteroides fragilis is a rare cause of septic arthritis. Most patients with B. fragilis septic arthritis have a chronic joint disease, particularly rheumatoid arthritis, and sources of infection are lesions of the gastrointestinal tract and the skin. We report a 69-year-old male, who developed B. fragilis septic arth...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02247808
更新日期：1997-11-01 00:00:00
abstract：:Four patients with rheumatoid nodulosis are here described, together with a review of cases reported to date in the literature. This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign cour...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207201
更新日期：1992-09-01 00:00:00
abstract：:We reviewed three cases of systemic lupus erythematosus (SLE) in children with mesenteric vasculitis (LMV) as initial presentation and analysed their clinical characteristics to improve the understanding of this disease. Three patients with SLE were admitted to our hospital and initially presented with gastrointestina...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-017-3841-0
更新日期：2018-01-01 00:00:00
abstract：:Musculoskeletal disorders represent a large and growing clinical challenge to primary care clinicians. Unfortunately, there appears to be a gap in current training and continuing education to meet this challenge. We used script concordance within a continuing medical education program entitled "Joint Adventures" to as...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0446-4
更新日期：2007-07-01 00:00:00
abstract：:Gout is a disease with acute and/or chronic inflammation and tissue damage induced by the precipitation of monosodium urate crystal (MSU) crystals in bone joints, kidneys, and subcutaneous sites. In recent years, with the continuous research on gout animal models and patient clinical investigations, the mechanism of i...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-020-05090-8
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:Gout is a common inflammatory disease, and the prevalence of gout in men is significantly higher than in women. Catechol-O-methyltransferase (COMT) regulates dopamine activity and metabolism, thereby participating in the uric acid metabolism, which in turn affects the occurrence of gout. Our study aimed to in...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04607-0
更新日期：2019-10-01 00:00:00
abstract：:The objectives of the study were to assess sleep disturbances in systemic lupus erythematosus (SLE) and to compare these with a working sample and a treatment-seeking sample reporting insomnia. The primary sample was 172 people with SLE. This sample represented 32% of all members of two lupus support association. Two ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-008-0884-2
更新日期：2008-09-01 00:00:00
abstract：:This pilot study aimed to evaluate the correlation between clinical symptoms and cartilage volume through MRI in patients with knee osteoarthritis after 48 weeks of treatment with Structum®. Multicenter, double-blind, placebo-controlled, parallel-group study. Symptomatic knee osteoarthritis patients aged 50-75 years r...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s10067-012-2022-4
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVE:Anti-cyclic citrullinated peptide 2 antibodies (anti-CCP2) and rheumatoid factor (RF) in rheumatoid arthritis (RA) has been extensively assessed in industrialized countries. We investigated the diagnostic and prognostic impact of anti-CCP2 and RF isotypes in a Sudanese cross-sectional RA cohort. METHODS:Cons...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究
doi：10.1007/s10067-019-04431-6
更新日期：2019-06-01 00:00:00
abstract：:To clarify the roles of neutrophils in anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitic neuropathy, we studied neutrophil extracellular traps (NETs) in peripheral nerve vasculitis. Stored nerve samples from 17 patients with microscopic polyangiitis (MPA) were immunohistochemically analyzed using a...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3546-4
更新日期：2017-04-01 00:00:00
abstract：:Our aim is to investigate the effects of three therapeutic approaches in the chronic low back pain on pain, spinal mobility, disability, psychological state, and aerobic capacity. Sixty patients with chronic low back pain were randomized to three groups: group 1, aerobic exercise + home exercise; group 2, physical the...
journal_title：Clinical rheumatology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10067-007-0815-7
更新日期：2008-07-01 00:00:00
abstract：:B cells in patients with rheumatoid arthritis (RA) are hyperactivated. Although B cell receptor signal transduction may be affected by various response regulators, CD22 plays an important role as a response regulator of B cells. Therefore, we investigated and examined CD22 expression on peripheral blood B cells of pat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0665-3
更新日期：2007-10-01 00:00:00
