Neutrophil extracellular traps in neuropathy with anti-neutrophil cytoplasmic autoantibody-associated microscopic polyangiitis.

abstract：:We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...

journal_title：Clinical rheumatology

authors： Yamamoto M,Yasuda M,Shiokawa S,Nobunaga M

更新日期：1992-03-01 00:00:00

abstract：:Tumour necrosis factor alpha (TNF alpha) and interleukin-2 (IL-2) are potential immunological mediators of pathogenetic changes in rheumatoid arthritis. We measured the concentrations of TNF alpha and IL-2 in plasma from 2 groups of patients suffering from rheumatoid arthritis (RA). One group had high and one had low ...

journal_title：Clinical rheumatology

authors： Espersen GT,Vestergaard M,Ernst E,Grunnet N

更新日期：1991-12-01 00:00:00

abstract：:A 12-week double-blind randomized drug trial followed by an open extension period of 36 weeks was carried out in 38 male patients with ankylosing spondylitis (AS) to compare the efficacy and safety of diflunisal (500 mg twice daily) and phenylbutazone (200 mg twice daily). Both drugs proved to be effective in improvin...

journal_title：Clinical rheumatology

authors： Franssen MJ,Gribnau FW,van de Putte LB

更新日期：1986-06-01 00:00:00

abstract：:Sarcoidosis is a multisystemic disease with cutaneous lesions present in about one fourth of patients. Cutaneous lesions may be specific or nonspecific based on the presence or the absence of sarcoidal granulomas. Subcutaneos sarcoidosis is the less frequent of the specific cutaneous lesions of sarcoidosis. We report ...

journal_title：Clinical rheumatology

authors： Dalle Vedove C,Colato C,Girolomoni G

更新日期：2011-08-01 00:00:00

abstract：:The aim of this study was to ascertain whether fibromyalgia patients with positive ANA develop other features of connective tissue disease over 2-4 years' follow-up. Patients attending our clinic with a diagnosis of fibromyalgia were identified. All ANA-positive patients (n = 12) were recruited and matched for age and...

journal_title：Clinical rheumatology

authors： Al-Allaf AW,Ottewell L,Pullar T

更新日期：2002-11-01 00:00:00

abstract：:The purpose of the study was to assess the 1-year outcome of definitive reactive arthritis (ReA) after a waterborne outbreak. A cohort of 21 patients (15 females and 6 males, median age 54 years) with ReA related to an extensive waterborne outbreak in Finland was clinically followed-up by rheumatologists with visits a...

journal_title：Clinical rheumatology

authors： Uotila TM,Antonen JA,Paakkala AS,Mustonen JT,Korpela MM,Pirkanmaa Waterborne Outbreak Study Group.

更新日期：2013-08-01 00:00:00

abstract：:Small synovial cysts are a common manifestation of juvenile idiopathic arthritis; large brachial cysts, however, are a rare sign of the disease and they must be differentiated from other soft tissue swelling which are not related to articular involvement. We describe the case of three children with juvenile idiopathic...

journal_title：Clinical rheumatology

authors： Dell'Era L,Vercellesi P,Forzenigo LV,Carnelli V,Corona F

更新日期：2008-12-01 00:00:00

abstract：:An understanding of the cytokine cascade in a rheumatoid joint has led to the development of new therapeutic options, including drugs targeting tumor necrosis factor-alpha (TNF-alpha). The safety profile of these agents in patients with hepatitis-induced liver disease, however, remains a concern because of risks assoc...

journal_title：Clinical rheumatology

authors： Li S,Kaur PP,Chan V,Berney S

更新日期：2009-07-01 00:00:00

abstract：:The antichromatin antibody (aCT) has been described as a useful marker for lupus nephropathy. The relevance of its nephritogenic potential may be appropriately evaluated in the context of renal histopathology. Therefore, the present study investigated the relationship of aCT with a particular histopathologic class of ...

journal_title：Clinical rheumatology

authors： Carvalho JF,Viana VS,Borba EF,do Nascimento AP,Leon EP,Testagrossa LA,Barros RT,Bonfá E

更新日期：2008-11-01 00:00:00

abstract：:Survival and outcomes have improved considerably among patients with juvenile dermatomyositis (JDM) in the west. However, mortality continues to be high in the developing world. There is paucity of literature on this aspect of JDM from developing countries. We reviewed case files of all patients with JDM registered in...

journal_title：Clinical rheumatology

authors： Singh S,Suri D,Aulakh R,Gupta A,Rawat A,Kumar RM

更新日期：2014-11-01 00:00:00

abstract：:Two cases of systemic lupus erythematosus (SLE) with autoimmune hepatitis are reported. Both patients had a mild form of SLE without central nervous system or renal involvement and showed a rapid response to corticosteroid therapy. Neither of them had antibodies to mitochondria, smooth muscle, and liver/kidney microso...

journal_title：Clinical rheumatology

authors： Satoh T,Hirakata M,Yoshida T,Matsumura M,Miyachi K,Mimori T,Akizuki M

更新日期：1997-05-01 00:00:00

abstract：:Extensive subcutaneous and muscular calcification developed in a patient having adult-onset dermatopolymyositis (DM-PM) with an 'overlap' connective tissue disease. We wish to emphasize the rarity of calcification in adult onset DM-PM, which is contrary to the generally held impression. ...

journal_title：Clinical rheumatology

authors： Cohen MG,Nash P,Webb J

更新日期：1986-12-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a disseminated non-Langerhans' cell histiocytosis with multisystem involvement, including characteristic sclerotic musculoskeletal lesions. We present the case of a 27-year-old woman with a fulminant course and atypical involvement by ECD manifesting as extensive cerebrovascular diseas...

journal_title：Clinical rheumatology

authors： Lyders EM,Kaushik S,Perez-Berenguer J,Henry DA

更新日期：2003-12-01 00:00:00

abstract：:It is commonly believed that infliximab-induced anticardiolipin antibody belongs to the IgM subclass but not the IgG subclass and that the IgM subclass could not produce clinical symptoms. However, we had a patient with scleroderma overlap/rheumatoid arthritis who developed thrombocytopenia associated with the appeara...

journal_title：Clinical rheumatology

authors： Hamaguchi M,Kawahito Y,Ishino H,Yoshida M,Yoshikawa T

更新日期：2007-06-01 00:00:00

abstract：:Infection is a major cause of morbidity and mortality among patients with systemic lupus erythematosus (SLE). To describe the pattern of serious infections in patients with SLE and to identify the predictors of infection-related mortality among SLE patients with serious infections, we prospectively studied all SLE pat...

journal_title：Clinical rheumatology

authors： Teh CL,Wan SA,Ling GR

更新日期：2018-08-01 00:00:00

abstract：:The aim of this study was to evaluate clinical remission and MDA in PsA patients who started TNF-inhibitors (TNFi) treatment with a 2-year follow-up. Concomitant therapies as well as comorbidities were assessed. Level of concordance of clinimetric indices and the potential predictive factors of remission/MDA were also...

journal_title：Clinical rheumatology

authors： Chimenti MS,Triggianese P,Conigliaro P,Tonelli M,Gigliucci G,Novelli L,Teoli M,Perricone R

更新日期：2017-10-01 00:00:00

abstract：:Mycobacterium bovis Bacillus Calmette-Guérin (BCG) instillations are used in bladder cancer treatment. Adverse effects can occur. Osteoarticular complications are mainly reactive arthritis, but true infections have been described, such as vertebral osteomyelitis. We made a review of M. bovis BCG vertebral osteomyeliti...

journal_title：Clinical rheumatology

authors： Cadiou S,Al Tabaa O,Nguyen CD,Faccin M,Guillin R,Revest M,Guggenbuhl P,Houvenagel E,Pertuiset E,Coiffier G

更新日期：2019-06-01 00:00:00

abstract：:CD30/CD30L and CD40/CD40L are molecules from the tumor necrosis factor (TNF) superfamily. They have a major effect on communications between the B and T cells, which leads to control of maturation, proliferation, and apoptosis of those cells. The aim of this study was to compare the levels of a soluble form of CD30 (s...

journal_title：Clinical rheumatology

authors： Ciferská H,Horák P,Hermanová Z,Ordeltová M,Zadrazil J,Tichý T,Scudla V

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a chronic inflammatory disease characterized by non-caseating granuloma which etiology is unknown yet. Adipokines are different proteins synthesized by adipose tissue that have an influence on angiogenesis, hemostasis, lipid metabolism, and immune system regulation. Adipokines may play a role ...

journal_title：Clinical rheumatology

authors： Kobak S,Semiz H,Akyildiz M,Gokduman A,Atabay T,Vural H

更新日期：2020-07-01 00:00:00

abstract：:Subcutaneous rheumatoid nodules occur commonly in advanced cases of rheumatoid arthritis and are the most common extra-articular lesion of this disease. We present a case of a very unusual giant rheumatoid nodule that developed on the lateral side of a knee. The case was devoid of systemic symptoms of arthritis and th...

journal_title：Clinical rheumatology

authors： Mine T,Tanaka H,Taguchi T,Ihara K,Ishida Y,Sugitani T,Kawai S

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:The frequency of eighth nerve lesions in patients with giant cell arteritis (GCA) has rarely been examined. However, sudden onset deafness has been recorded as a presenting feature of GCA on several occasions. This study sought to establish how common this and other symptoms of eighth nerve involvement are...

journal_title：Clinical rheumatology

authors： Saravanan V,Pugmire S,Smith M,Kelly C

更新日期：2019-12-01 00:00:00

abstract：:Until recently, renal crisis was the most significant cause of morbidity and mortality in patients with scleroderma (SSc). Nowadays, following the introduction of angiotensin-converting enzyme inhibitors used in renovascular hypertension, pulmonary fibrosis and pulmonary hypertension have become the most common causes...

journal_title：Clinical rheumatology

authors： Davas EM,Peppas C,Maragou M,Alvanou E,Hondros D,Dantis PC

更新日期：1999-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder. Renal involvement has the worst prognosis. However, renal cortical necrosis is extremely unusual in SLE. In this case report, we describe the autopsy findings in a young female patient with SLE presenting with renal failure. At autopsy, there w...

journal_title：Clinical rheumatology

authors： Uppin MS,Rajasekhar L,Swetha H,Srinivasan VR,Prayaga AK

更新日期：2010-07-01 00:00:00

abstract：:Amyloid arthropathy is said to be distinguished roentgenographically from rheumatoid arthritis by the absence of joint space narrowing and the absence of articular erosions. We present a patient with multiple myeloma with swelling, stiffness and firm synovial thickening of the wrists, metacarpophalangeal joints and pr...

journal_title：Clinical rheumatology

authors： Leonard PA,Clegg DO,Lee RG

更新日期：1985-06-01 00:00:00

abstract：:Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. Lymphadenopathy is rare in patients with WG. Here, we present the first case of WG whose initial manifestation was superficial lymphadenopathy (i.e. supraclavicular and axillary lymphadenop...

journal_title：Clinical rheumatology

authors： Hashizume T,Yamaguchi T,Matsushita K

更新日期：2002-11-01 00:00:00

abstract：:Simultaneous occurrence of subacute cutaneous lupus erythematosus and malignancy has rarely been reported. We report the first case of subacute cutaneous lupus erythematosus associated with Hodgkin's disease. Although our case does not fulfill the criteria of paraneoplastic process, a relationship between the two diso...

journal_title：Clinical rheumatology

authors： Castanet J,Taillan B,Lacour JP,Garnier G,Perrin C,Ortonne JP

更新日期：1995-11-01 00:00:00

abstract：:The above article originally published with an error present in Table 2 and is now presented correctly in this article. ...

journal_title：Clinical rheumatology

authors： Kizaki K,Uchida S,Yamashita F,Tsukamoto M,Azuma K

更新日期：2018-10-01 00:00:00

abstract：:We describe the case of a 26-year-old African female who was treated successfully with belimumab in a case of severe membranous lupus nephritis and retinal vasculitis, resistant to first line therapy. She presented initially with chronic dacryoadenitis and screening showed nephrotic-range proteinuria. Biopsy of the ki...

journal_title：Clinical rheumatology

authors： De Scheerder MA,Boey O,Mahieu E,Vanuytsel J,Bogaert AM

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study is to find out the outcome of 28 patients who got the diagnosis of primary fibromyalgia (pFM) 26 years ago. In 1986, 56 patients with widespread pain were examined and filled in a base questionnaire (BQ). Of them, 42 fulfilled the Yunus criteria for pFM. Twenty-six years later, addresses of 38 pa...

journal_title：Clinical rheumatology

authors： Isomeri R,Mikkelsson M,Partinen M,Kauppi MJ

更新日期：2018-05-01 00:00:00

abstract：:In a Sidonian sarcophagus, from the Late Antique/early Christian period, skeletal remains of two persons were found. One of them, male, 30-50 years old, was found almost completely ankylosed, with highly osteoporotic bones and prominent erosion of joint surfaces. We diagnosed rheumatoid arthritis based on the eroded o...

journal_title：Clinical rheumatology

authors： Bašić Ž,Jerković I,Kružić I,Anđelinović Š

更新日期：2017-01-01 00:00:00