The spectrum and clinical significance of myositis-specific autoantibodies in Chinese patients with idiopathic inflammatory myopathies.

abstract：:We aimed to investigate the possible effects of thioredoxin 1 (Trx1) on the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) and elucidate the possible mechanisms involved. We investigated the distribution and expression of Trx1 in synovial tissues from RA and osteoarthritis (...

journal_title：Clinical rheumatology

authors： Lu T,Zong M,Fan S,Lu Y,Yu S,Fan L

更新日期：2018-01-01 00:00:00

abstract：:The pathogenesis of the idiopathic inflammatory myopathies has been postulated to be an environmental trigger causing the expression of the disease in a genetically predisposed patient. We report a case of anti-Jo1 antibody-positive myositis which was associated with pleural effusions, pericardial effusion with tampon...

journal_title：Clinical rheumatology

authors： Derk CT,Sandorfi N,Curtis MT

更新日期：2004-08-01 00:00:00

abstract：:The objective of this study was to understand the patient experience of musculoskeletal imaging tests for investigation of inflammatory arthritis and factors that contribute to this experience. We conducted a thematic analysis of semi-structured interviews with 33 patients who had a recent peripheral joint musculoskel...

journal_title：Clinical rheumatology

authors： Bourke S,Taylor WJ,Doyle AJ,Gott M,Dalbeth N

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:(1) Development and validation of a composite ultrasound score (cUSS) for the diagnosis of carpal tunnel syndrome (CTS). (2) To predict treatment response after local corticosteroid injection. METHODS:Wrists of CTS patients and controls were evaluated with high-resolution ultrasound and cross-sectional area...

journal_title：Clinical rheumatology

authors： Goswami RP,Sit H,Chatterjee M,Lahiri D,Sircar G,Ghosh P

更新日期：2020-07-21 00:00:00

abstract：:As a class, tumor necrosis factor (TNF)-alpha inhibitors have provided clinicians significant control over chronic inflammatory diseases. With their widespread use has come the emergence of new side effects such as the reactivation of latent infections. One such infection that may reactivate is the hepatitis B virus (...

journal_title：Clinical rheumatology

authors： Carroll MB,Forgione MA

更新日期：2010-09-01 00:00:00

abstract：:In juvenile chronic arthritis (JCA) the indices of disease activity, such as joint swelling, pain, tenderness, and limitation of motion, may poorly correlate with the degree of functional impairment. Since the improvement of functional capacity is one of the main objectives of treatment, we evaluated the effect of met...

journal_title：Clinical rheumatology

authors： Ravelli A,Viola S,Ramenghi B,Di Fuccia G,Ruperto N,Zonta L,Martini A

更新日期：1995-05-01 00:00:00

abstract：:Osteonecrosis (ON) is a clinical entity characterized by death of bone marrow and trabecular bone as a result of disruption of blood supply to the bone. The antiphospholipid (APL) syndrome is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with APL antibodies. The involvement ...

journal_title：Clinical rheumatology

authors： Rostom S,Bahiri R,Hajjaj-Hassouni N

更新日期：2008-02-01 00:00:00

abstract：:This study demonstrates whether serum β2-microglobulin (β2-MG) level can be an indicator of the status of systemic lupus erythematosus (SLE) and adult-onset Still's disease (AOSD), and development of hemophagocytic syndrome (HPS) complication. Serum β2-MG level was compared between the active and inactive statuses of ...

journal_title：Clinical rheumatology

authors： Wakabayashi K,Inokuma S,Matsubara E,Onishi K,Asashima H,Nakachi S,Hagiwara K

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:The primary objective was to evaluate the impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department. Secondary objectives were to determine (i) if medication history discrepancies were detected more frequently in the elderly or not, and (ii) if the...

journal_title：Clinical rheumatology

authors： Soubieux A,Chenailler C,Lattard C,Banse C,Kozyreff-Meurice M,Gondé H,Lequerré T,Vittecoq O,Varin R

更新日期：2021-01-01 00:00:00

abstract：:Sudden death following steroid pulse therapy has been recently reported. Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondylitis unresponsive t...

journal_title：Clinical rheumatology

authors： Nasswetter G,Piñeiro DJ,Garcia Morteo OM,Maldonado Cocco JA,Barreira JC,Vazquez Blanco M

更新日期：1984-03-01 00:00:00

abstract：:This study aims to explore the effectiveness of low dose of etanercept (ETN) in patients with ankylosing spondylitis (AS) who achieve a good control of their disease in daily clinical practice. This is a case series of AS patients treated with ETN. According to the judgment of the treating rheumatologist and patient's...

journal_title：Clinical rheumatology

authors： Navarro-Compán V,Moreira V,Ariza-Ariza R,Hernández-Cruz B,Vargas-Lebrón C,Navarro-Sarabia F

更新日期：2011-07-01 00:00:00

abstract：:HLA-II molecules are critical in triggering human immune response, especially in activating CD4+ T cells. HLA-DP, belonging to HLA-II molecules, draws increasing attention for its role in presentation of viral antigen and autoantigen to T cells. Researches reported single nucleotide polymorphism (SNP) of HLA-DP associ...

journal_title：Clinical rheumatology

authors： Huang Z,Niu Q,Yang B,Zhang J,Yang M,Xu H,Cai B,Hu J,Wu Y,Wang L

更新日期：2018-07-01 00:00:00

abstract：:The study aimed to determine whether unique clinical patterns of AS may exist in China, specifically to explore the different clinical manifestations caused by gender, HLA-B27 status, and age at disease onset. The multicenter cross-sectional survey was conducted and 1251 patients were enrolled across China, representi...

journal_title：Clinical rheumatology

authors： Qian Q,Xu X,He H,Ji H,Zhang H,Ding Y,Dai SM,Zou Y,Zhu Q,Yang C,Ye S,Jiang L,Tang JP,Tong Q,He D,Zhao D,Li Y,Ma Y,Zhou J,Yuan Z,Zhang J,Jin L,Zhou X,Reveille JD,Zou H,Wang J

更新日期：2017-07-01 00:00:00

abstract：:Knee osteoarthritis (KOA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Several inflammatory markers and cartilage degradation products can be used as biomarkers in OA. The key factors of bone metabolism in normal joint bone, dickkopf-1 (DKK1) and o...

journal_title：Clinical rheumatology

authors： Min S,Wang C,Lu W,Xu Z,Shi D,Chen D,Teng H,Jiang Q

更新日期：2017-10-01 00:00:00

abstract：:The aim of this study was to evaluate in systemic sclerosis (SSc) retrospectively the effect of Bosentan and Sildenafil and their combination on Raynaud's phenomenon (RP), function, and capillaroscopic patterns. One hundred and twenty-three SSc patients (mean age ± sd, 57.69 ± 14.07 years) were retrospectively evaluat...

journal_title：Clinical rheumatology

authors： Bellando-Randone S,Lepri G,Bruni C,Blagojevic J,Radicati A,Cometi L,De Paulis A,Matucci-Cerinic M,Guiducci S

更新日期：2016-01-01 00:00:00

abstract：:The aim of the study was to analyse the gynaecologic history of 150 Brazilian patients with systemic sclerosis (SSc) by comparing the outcome of the pregnancies before and after disease onset and in the two clinical variants of SSc, as well as to assess the effects of the pregnancy on the progress of the disease. A re...

journal_title：Clinical rheumatology

authors： Sampaio-Barros PD,Samara AM,Marques Neto JF

更新日期：2000-01-01 00:00:00

abstract：:Small differences in inbred animals with a gene for arthritis must be the cause that some of them evolve the disease and others not. These differences are partly stochastic, caused by thermal movement of molecules. It is possible that their effect is amplified by a network of cytokines, known to play an important role...

journal_title：Clinical rheumatology

authors： Daams JH,Westerhoff HV

更新日期：1996-01-01 00:00:00

abstract：:The levels of 63 cytokines, chemokines, and growth factors were measured in the serum of four patients with idiopathic morphea and of one patient with vitamin K1-induced morphea employing a multiplex assay to identify the role of inflammatory/immunologic events in their pathogenesis. Full-thickness skin biopsies of af...

journal_title：Clinical rheumatology

authors： Cox LA,Webster GF,Piera-Velazquez S,Jimenez SA

更新日期：2017-05-01 00:00:00

abstract：:The aim of this study was to assess the role of oxidative stress in the pathogenesis of Henoch-Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase (ARYL), and paraoxonase (PON) as antioxidant enzymes and serum malondialdehyde (MDA) level as an indicator of lipid peroxidation, together wi...

journal_title：Clinical rheumatology

authors： Ece A,Kelekçi S,Kocamaz H,Hekimoğlu A,Balik H,Yolbaş I,Erel O

更新日期：2008-02-01 00:00:00

abstract：:The level of the N terminal fragment of procollagen III (P3NP) levels of 100 consecutive patients affected by rheumatoid arthritis (RA) were evaluated in comparison with disease activity markers (erythrocytes sedimentation rate, C reactive protein), immunological status (rheumatoid factors, immune complexes) and joint...

journal_title：Clinical rheumatology

authors： Tebib JG,Viguier P,Noel E,Colson F,Barbier Y,Bouvier M

更新日期：1992-12-01 00:00:00

abstract：:Very recently, several studies have convincingly demonstrated the role of infection in the development of the antiphospholipid syndrome. Cross antibody-mediated reactivity due to molecular mimicry between endothelial glycoproteins and microbial products was considered as an important pathogenic mechanism. However, ano...

journal_title：Clinical rheumatology

authors： Rozin AP

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:Alkaptonuria (AKU) is a rare metabolic disease. The global incidence is 1:100,000 to 1:250,000. However, identification of a founder mutation in a gypsy population from India prompted us to study the prevalence of AKU in this population and to do molecular typing in referred cases of AKU from the rest of I...

journal_title：Clinical rheumatology

authors： Danda S,Mohan S,Devaraj P,Dutta AK,Nampoothiri S,Yesodharan D,Phadke SR,Jalan AB,Thangaraj K,Verma IC,Danda D,Jebaraj I

更新日期：2020-09-01 00:00:00

abstract：:This study shows that N-acetyl-galactosamine and N-acetyl-glucosamine can diminish the production of superoxide anion from cytochalasin-B treated PMNs stimulated with FMLP. Inhibition ranged from 80.9% to 1.8%. N-acetyl-galactosamine was superior to N-acetyl-glucosamine, but both showed their action in a dose-related ...

journal_title：Clinical rheumatology

authors： Kamel M,Alnahdi M

更新日期：1992-06-01 00:00:00

abstract：:The thermographic appearance of the sacro-iliac joints in health and in active inflammation has been established on the basis of 72 thermographic examinations of healthy volunteers and 82 examinations of patients with clinically and radiographically active disease. In the latter group a certain number of cases showed ...

journal_title：Clinical rheumatology

authors： Jacobsson H,Vestersköld L

更新日期：1985-12-01 00:00:00

abstract：:To estimate the mortality and describe the causes of death in a large multicenter cohort of hospitalized patients with SLE in China. This was a retrospective study of a nationwide SLE cohort (10 centers, 29,510 hospitalized patients) from 2005 to 2014 in China. Standardized mortality ratios (SMRs) were calculated for ...

journal_title：Clinical rheumatology

authors： Wu XY,Yang M,Xie YS,Xiao WG,Lin J,Zhou B,Guan X,Luo CN,Che N,Liu XZ,Wang C,Teng JL,Cheng XB,Ye JN,Su YT,Shi H,Yin YF,Liu MR,Sun Y,Hu QY,Zhou ZC,Chi HH,Liu Y,Zhang X,Chen JW,Zhang MJ,Zhao DB,Yang CD,

更新日期：2019-01-01 00:00:00

abstract：:We describe the case of a patient with anticentriole antibody-positive scleroderma spectrum disorder (SSD) who developed pulmonary hypertension. A 54-year-old woman had noticed Raynaud's phenomenon and digital ulcers during the winter for the past 10 years. Although sclerodactyly was not present, digital ulcers, swell...

journal_title：Clinical rheumatology

authors： Hayakawa I,Sato S,Hasegawa M,Echigo T,Takehara K

更新日期：2004-06-01 00:00:00

abstract：:A 67-year-old woman, suffering from continuous hemoptysis, was admitted to our hospital where she was managed with mechanical ventilation. Computed tomography of the chest demonstrated bilateral massive alveolar hemorrhage without evidence of infectious disease. She was diagnosed with anti-myeloperoxidase antineutroph...

journal_title：Clinical rheumatology

authors： Kawasaki S,Nakamura H,Honda E,Iwanaga N,Kawakami A,Ida H,Origuchi T,Honda S,Tsuchihashi Y,Yoshimine H,Eguchi K

更新日期：2007-07-01 00:00:00

abstract：:A pair of identical twins suffering from ankylosing spondylitis is reported. One brother developed an earlier-onset disease and showed ossification of the posterior longitudinal ligament and the flavum ligament in his cervical spine. ...

journal_title：Clinical rheumatology

authors： Olivieri I,Pappone N,Padula A,Rengo C,Ruju GP,Pucino A,Trippi D,Ferri S,Pasero G

更新日期：1994-06-01 00:00:00

abstract：INTRODUCTION:The frequency of eighth nerve lesions in patients with giant cell arteritis (GCA) has rarely been examined. However, sudden onset deafness has been recorded as a presenting feature of GCA on several occasions. This study sought to establish how common this and other symptoms of eighth nerve involvement are...

journal_title：Clinical rheumatology

authors： Saravanan V,Pugmire S,Smith M,Kelly C

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to evaluate the relationship between historical height loss (HHL) and prevalent vertebral fractures (VF) in postmenopausal Moroccan women and to estimate its accuracy as a clinical test for detecting VF. Two hundred eighty-eight postmenopausal women were studied. All subjects had bone density...

journal_title：Clinical rheumatology

authors： Bennani L,Allali F,Rostom S,Hmamouchi I,Khazzani H,El Mansouri L,Ichchou L,Abourazzak FZ,Abouqal R,Hajjaj-Hassouni N

更新日期：2009-11-01 00:00:00