Rheumatoid nodulosis: a puzzling variant of rheumatoid arthritis.

abstract：:The aim of this study was to identify and evaluate laboratory parameters associated with normal bone mineral density (BMD) and to test if -308 tumour necrosis factor (TNF) alpha gene promoter polymorphisms could influence BMD. We performed a comparative cross-sectional study of four main groups: young healthy individu...

journal_title：Clinical rheumatology

authors： Canhao H,Fonseca JE,Caetano-Lopes J,Saldanha C,Queiroz MV

更新日期：2008-03-01 00:00:00

abstract：:The pharmacokinetic profile of a single 10 mg oral dose of prednisolone was studied in three groups of six patients with rheumatoid arthritis (RA), polymyalgia rheumatica (PMR) and bronchial asthma (BA) who were already receiving steroid therapy. A fourth group of age and sex-matched normal controls was also studied. ...

journal_title：Clinical rheumatology

authors： Taggart AJ,Astbury C,Dixon JS,Bird HA

更新日期：1986-09-01 00:00:00

abstract：:With the aim of evaluating the role of 1,25 dihydroxyvitamin D in the pathogenesis of osteoporosis, this hormone was studied in 90 subjects. They were divided into three groups: the first group consisted of 30 normal female subjects (aged 30 to 45); the second group comprised 30 elderly female subjects (aged 67 to 90)...

journal_title：Clinical rheumatology

authors： Cantatore FP,Carrozzo M

更新日期：1990-06-01 00:00:00

abstract：:Immunoglobulins are often high in active rheumatoid arthritis and fall when treatment with a slow-acting anti-rheumatic drug is instituted. We assessed the value of monitoring immunoglobulins during penicillamine therapy; 145 patients were followed for up to 5 years, IgA, IgM and IgG levels were compared to 12 other c...

journal_title：Clinical rheumatology

authors： Williams A,Scott DL,Greenwood A,Huskisson EC

更新日期：1988-09-01 00:00:00

abstract：:We and others have previously shown that IL-17 is elevated in the synovial fluid of patients with reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) having acute synovitis. Major source for IL-17 is Th17 cells, which differentiate from Th0 cells under the influence of TGF-β and IL-6, IL1-β and are ma...

journal_title：Clinical rheumatology

authors： Singh AK,Misra R,Aggarwal A

更新日期：2011-06-01 00:00:00

abstract：:We aimed to evaluate the presence of peripheral antineutrophil cytoplasmic antibodies (p-ANCA) and cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) in children with SLE and to correlate its association of laboratory findings. Twenty-one children with SLE were studied. Serum samples in patients were tested by...

journal_title：Clinical rheumatology

authors： Bakkaloglu A,Topaloglu R,Saatçi U,Ozdemir S,Ozen S,Başsoy Y,Beşbaş N

更新日期：1998-01-01 00:00:00

abstract：:HLA-II molecules are critical in triggering human immune response, especially in activating CD4+ T cells. HLA-DP, belonging to HLA-II molecules, draws increasing attention for its role in presentation of viral antigen and autoantigen to T cells. Researches reported single nucleotide polymorphism (SNP) of HLA-DP associ...

journal_title：Clinical rheumatology

authors： Huang Z,Niu Q,Yang B,Zhang J,Yang M,Xu H,Cai B,Hu J,Wu Y,Wang L

更新日期：2018-07-01 00:00:00

abstract：:The authors studied the incidence of atlanto-axial joint involvement by conventional radiography and CT in 183 patients with classical or definite rheumatoid arthritis (RA). In determining lesions the significance of factors such as age, sex, duration and severity of the disease was evaluated. Atlanto-axial subluxatio...

journal_title：Clinical rheumatology

authors： Montemerani M,Venturi C,Bracco S,Coviello G,Minari C,Fioravanti A,Marcolongo R

更新日期：1994-09-01 00:00:00

abstract：:Transient receptor potential melastatin 7 (TRPM7) is involved in both normal physiological processes and pathology of various diseases. The purpose of this study was to explore the function and underlying mechanisms of TRPM7 channels in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) apoptosis induced by...

journal_title：Clinical rheumatology

authors： Li X,Wang X,Wang Y,Li X,Huang C,Li J

更新日期：2014-11-01 00:00:00

abstract：:We report the case of a 57-year-old woman presenting with persistent cough, weight loss, and fever. An extensive work-up revealed laboratory signs of inflammation and a mild thickening of the aortic wall on computed tomographic scan of the thorax. These findings raised the suspicion of large vessel vasculitis that was...

journal_title：Clinical rheumatology

authors： Van der Schueren B,Lambert M

更新日期：2005-08-01 00:00:00

abstract：:Gout is a disease with acute and/or chronic inflammation and tissue damage induced by the precipitation of monosodium urate crystal (MSU) crystals in bone joints, kidneys, and subcutaneous sites. In recent years, with the continuous research on gout animal models and patient clinical investigations, the mechanism of i...

journal_title：Clinical rheumatology

authors： Wu M,Tian Y,Wang Q,Guo C

更新日期：2020-10-01 00:00:00

abstract：:The population of North Dakota is predominantly of Scandinavian (Norwegian) or German descent. We analyzed a cohort of all patients diagnosed with palindromic rheumatism (PR) and followed-up (by the investigator PK) at the St. Alexius Medical Center, Specialty Clinics, Bismarck, North Dakota, from August 16, 2006 to S...

journal_title：Clinical rheumatology

authors： Kaushik P

更新日期：2010-01-01 00:00:00

abstract：:As a class, tumor necrosis factor (TNF)-alpha inhibitors have provided clinicians significant control over chronic inflammatory diseases. With their widespread use has come the emergence of new side effects such as the reactivation of latent infections. One such infection that may reactivate is the hepatitis B virus (...

journal_title：Clinical rheumatology

authors： Carroll MB,Forgione MA

更新日期：2010-09-01 00:00:00

abstract：:Patients with osteoporosis often have chronic kidney disease (CKD). CKD is associated with bone and mineral disturbances, renal osteodystrophy, which like osteoporosis leads to a higher risk of fractures. Bisphosphonates are first-line therapy for osteoporosis; however, these are contra-indicated in patients with a GF...

journal_title：Clinical rheumatology

authors： Schipper LG,Fleuren HW,van den Bergh JP,Meinardi JR,Veldman BA,Kramers C

更新日期：2015-08-01 00:00:00

abstract：:Gonadotropin-releasing hormone (GnRH) is the first key hormone of reproduction. GnRH analogs are extensively used in in vitro fertilization and treatment of sex hormone-dependent cancers due to their ability to bring about 'chemical castration'. Recently it has been showed that it also plays an important role in the m...

journal_title：Clinical rheumatology

authors： Lazúrová I,Angelovicová J,Petríková J,Calfová A,Oetterová M,Svajdler M

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The early detection of psoriatic arthritis (PSA) poses a challenge to rheumatologists, even when their diagnosis is aided by sonography. In order to facilitate early detection of PSA among patients with psoriasis (PSO), we retrospectively analyzed of the relationships between serological markers and comorbid...

journal_title：Clinical rheumatology

authors： Su YJ

更新日期：2020-12-01 00:00:00

abstract：:There is an increasing concern over generalizability of trial results. We investigated eligibility criteria of knee osteoarthritis clinical trials. Eligible trials were randomized, placebo-controlled trials that were identified by searches in MEDLINE, SCOPUS, and the Cochrane Central Register of Controlled Trials. We ...

journal_title：Clinical rheumatology

authors： Koog YH,Wi H,Jung WY

更新日期：2013-11-01 00:00:00

abstract：:The prostaglandin series of bioactive compounds is formed by the interaction of two distinct but related enzymes, cyclo-oxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is a constitutive form which is present mainly in the gastric mucosa, kidney and platelets. COX-2 is mainly an inducible form, although also to...

journal_title：Clinical rheumatology

authors： Everts B,Währborg P,Hedner T

更新日期：2000-01-01 00:00:00

abstract：:The aim of this study was to describe a single-center experience in the treatment and follow-up of cystoid macular edema patients. Clinical records of all patients with cystoid macular edema followed up in the Rheumatologic and Ophthalmological Unit of our center between 1993 and 2013 were retrospectively evaluated. T...

journal_title：Clinical rheumatology

authors： Taraborelli M,Cavazzana I,Fredi M,Airò P,Nascimbeni G,Tincani A,Franceschini F

更新日期：2015-04-01 00:00:00

abstract：:Central nervous involvement (CNS) is uncommon manifestation of Wegener's granulomatosis (WG). We are describing a patient with refractory WG with CNS involvement which responded to rituximab. This lady presented with nodular scleritis. Three months later, she developed headache, vision loss with complete opthalmoplegi...

journal_title：Clinical rheumatology

authors： Sharma A,Kumar S,Wanchu A,Lal V,Singh R,Gupta V,Singh S,Gupta A

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The objectives of our study were to compare the efficacy of febuxostat with allopurinol in Thai subjects with gout, as well as to determine the predictive factors of responsiveness to urate-lowering agents and to evaluate the safety of febuxostat in a real-world setting. METHODS:The study was a retrospective...

journal_title：Clinical rheumatology

authors： Lertnawapan R,Jatuworapruk K

更新日期：2021-01-01 00:00:00

abstract：:Two cases of systemic lupus erythematosus (SLE) with autoimmune hepatitis are reported. Both patients had a mild form of SLE without central nervous system or renal involvement and showed a rapid response to corticosteroid therapy. Neither of them had antibodies to mitochondria, smooth muscle, and liver/kidney microso...

journal_title：Clinical rheumatology

authors： Satoh T,Hirakata M,Yoshida T,Matsumura M,Miyachi K,Mimori T,Akizuki M

更新日期：1997-05-01 00:00:00

abstract：:This study aims to examine the needs and preferences regarding the delivery of health care services and information provision and their determinants in patients with systemic sclerosis (SSc). A questionnaire was sent to 77 SSc outpatients, comprising 27 items on health care needs within the domains physical, psycholog...

journal_title：Clinical rheumatology

authors： Schouffoer AA,Zirkzee EJ,Henquet SM,Caljouw MA,Steup-Beekman GM,van Laar JM,Vlieland TP

更新日期：2011-06-01 00:00:00

abstract：:Two major complications in scleroderma patients that cause substantial morbidity and mortality are ischemic digital lesions (DL) and pulmonary hypertension (PH). The clinician's ability to predict which patients will develop these complications is imperfect. We conducted a prospective observational cohort study of 300...

journal_title：Clinical rheumatology

authors： Mecoli CA,Shah AA,Boin F,Wigley FM,Hummers LK

更新日期：2018-09-01 00:00:00

abstract：:The cellular localization of the Ro/SS-A antigen was defined using indirect immunofluorescence and eight monospecific anti- Ro/SS-A antisera which were identified by immunoblotting. Several mammalian tissues were used as substrates. The Ro/SS-A antigen was located mainly in the nucleus of dog liver and Hep-2-cells, an...

journal_title：Clinical rheumatology

authors： Lopez-Robles E,Herrera-Esparza R,Avalos-Diaz E

更新日期：1986-01-01 00:00:00

abstract：:Physical therapy and exercise (recreational activity) are the cornerstones of non-pharmacologic therapy in axial spondyloarthritis (AxSpA) [1, 2]. These are components of physical activity, though physical activity is made up of activities beyond these and also include occupational activity. Not all activities in AxSp...

journal_title：Clinical rheumatology

authors： Gensler LS

更新日期：2016-06-01 00:00:00

abstract：:Atherosclerosis plays a key role in cardiovascular disease in patients with rheumatoid arthritis (RA). Although therapy with TNF-alpha antagonists has resulted in dramatic improvement in the prognosis of RA, its effects on circulatory lipids are unclear. We conducted a systematic review of the literature to summarize ...

journal_title：Clinical rheumatology

authors： Pollono EN,Lopez-Olivo MA,Lopez JA,Suarez-Almazor ME

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:To explore the link between ultrasonographic features of dactylitis in psoriatic arthritis (PsA) and symptoms, digital tenderness and duration of dactylitis. METHODS:Forty-eight cases of PsA dactylitis were investigated using high frequency ultrasound (US) both in grey scale (GS) and Power Doppler (PD), eva...

journal_title：Clinical rheumatology

authors： Girolimetto N,Costa L,Mancarella L,Addimanda O,Bottiglieri P,Santelli F,Meliconi R,Peluso R,Del Puente A,Macchioni P,Salvarani C,McGonagle D,Scarpa R,Caso F

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:This study aimed to investigate the relationship among smoking, TNF-α-blocker therapy, and the dynamic changes in gut microbiota in patients with ankylosing spondylitis (AS). METHODS:Using a 16S rRNA sequence, 98 fecal samples of 20 AS patients collected after 0, 1, 3 and 6 months of anti-TNF-α treatment an...

journal_title：Clinical rheumatology

authors： Zhang F,Ma C,Zhang B,Bi L

更新日期：2020-09-01 00:00:00

abstract：:Cardiovascular disease is a major health care problem and the most common cause of death among individuals from developed nations. Our understanding of atherosclerosis has evolved from a passive process resulting in narrowing of the lumen and consequent myocardial ischemia to a dynamic process that involves inflammati...

journal_title：Clinical rheumatology

authors： Chung CP,Avalos I,Raggi P,Stein CM

更新日期：2007-08-01 00:00:00