Abstract:
:The aim of the study was to investigate the long-term outcome of non-specific seronegative oligoarthritis in adults. The study included 64 adult patients with recent (<6 months) seronegative oligoarthritis (rheumatoid factor negative, number of swollen joints 1-4 during the first 6 months). Follow-up examinations were carried out at onset and at 1, 3 and 8 years from entry. A total of 47 patients attended the 23-year follow-up. The endpoint outcome was good. Seven had mild erosions in the hands or feet. Only one patient with HLA-B27 developed bilateral sacroiliitis. Three patients had retired from work because of joint disease. The functional outcome of the patients analysed by HAQ was very good after 23 years: 0 in 33 and 0.1-0.9 in 12 of the 47 patients. Reclassification revealed a certain heterogeneity: one case each of rheumatoid arthritis, SLE and ankylosing spondylitis, two cases of post-traumatic arthritis, four of osteoarthrosis, and six of possible reactive arthritis. Out of the remaining 49 patients 15 were HLA-B27 positive and 16 had at least one of the psoriasis-related HLA antigens (HLA-B13, 17, w16). In conclusion, our 23-year prospective follow-up study of patients with seronegative oligoarthritis confirms their favourable outcome. The reason is that the endpoint diagnoses seemed to be similar to those of mild spondylarthropathies.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Jäntti JK,Kaarela K,Lehtinen KEdoi
10.1007/s100670200096subject
Has Abstractpub_date
2002-09-01 00:00:00pages
353-6issue
5eissn
0770-3198issn
1434-9949journal_volume
21pub_type
杂志文章abstract::Calciphylaxis is a rare and life-threatening condition of progressive cutaneous necrosis secondary to small and medium-sized vessel calcification that is seen almost exclusively in patients with end-stage renal disease and hyperparathyroidism. We report a case of calciphylaxis that may very well be due to a long-term ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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pub_type: 杂志文章,评审
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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doi:10.1007/s10067-009-1305-x
更新日期:2010-02-01 00:00:00
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pub_type: 临床试验,杂志文章
doi:10.1007/s100670170018
更新日期:2001-01-01 00:00:00
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