Predictors of sustained clinical response in patients with Behçet's disease-related uveitis treated with infliximab and adalimumab.

abstract：:We and others have previously shown that IL-17 is elevated in the synovial fluid of patients with reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) having acute synovitis. Major source for IL-17 is Th17 cells, which differentiate from Th0 cells under the influence of TGF-β and IL-6, IL1-β and are ma...

journal_title：Clinical rheumatology

authors： Singh AK,Misra R,Aggarwal A

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:It has been suggested that in some patients non-traumatic aseptic osteonecrosis of the hip (AOH) could be the result of the intra-osseous thrombosis. Antiphospholipid antibodies (APL) have been associated with venous and arterial occlusive events and the association between AOH and APL syndrome has been repo...

journal_title：Clinical rheumatology

authors： Laroche M,Ludot I,Thiechart M,Viguier G,Dromer C,Mazières B

更新日期：1997-06-01 00:00:00

abstract：:Gout is a disease with acute and/or chronic inflammation and tissue damage induced by the precipitation of monosodium urate crystal (MSU) crystals in bone joints, kidneys, and subcutaneous sites. In recent years, with the continuous research on gout animal models and patient clinical investigations, the mechanism of i...

journal_title：Clinical rheumatology

authors： Wu M,Tian Y,Wang Q,Guo C

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Alkaptonuria (AKU) is a rare metabolic disease. The global incidence is 1:100,000 to 1:250,000. However, identification of a founder mutation in a gypsy population from India prompted us to study the prevalence of AKU in this population and to do molecular typing in referred cases of AKU from the rest of I...

journal_title：Clinical rheumatology

authors： Danda S,Mohan S,Devaraj P,Dutta AK,Nampoothiri S,Yesodharan D,Phadke SR,Jalan AB,Thangaraj K,Verma IC,Danda D,Jebaraj I

更新日期：2020-09-01 00:00:00

abstract：:Over the last few years, several studies in patients with systemic lupus erythematosus (SLE) have demonstrated an association between valvulopathy, including Libman-Sacks endocarditis (LS) and the presence of antiphospholipid antibodies (aPL), suggesting a role of these antibodies in the pathogenesis of the lesions. O...

journal_title：Clinical rheumatology

authors： Mattos P,Santiago MB

更新日期：2011-02-01 00:00:00

abstract：:Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyosi...

journal_title：Clinical rheumatology

authors： Liu FC,Chen CH,Chao TY

更新日期：2007-07-01 00:00:00

abstract：:Paediatric systemic lupus erythematosus (pSLE) refers to childhood-onset systemic lupus erythematosus. pSLE has its own unique characteristics, and its pathogenesis is unclear. To study the relationship between microRNAs (miRNAs) and pSLE, we selected three pSLE patients who were newly diagnosed and had not yet been t...

journal_title：Clinical rheumatology

authors： Zhu J,Huang X,Su G,Wang L,Wu F,Zhang T,Song G

更新日期：2014-06-01 00:00:00

abstract：:We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...

journal_title：Clinical rheumatology

authors： Yamamoto M,Yasuda M,Shiokawa S,Nobunaga M

更新日期：1992-03-01 00:00:00

abstract：:A 73-year-old patient, whose hip was completely destroyed by pigmented villonodular synovitis, was successfully treated by a total prosthetic replacement of this articulation. The etiopathogenesis of the illness is uncertain. Its' localization in the hip is, fortunately, a rare occurrence. It can be responsible for fr...

journal_title：Clinical rheumatology

authors： Descamps F,Yasik E,Hardy D,Lafontaine M,Delince P

更新日期：1991-06-01 00:00:00

abstract：:The role of exposure to solvents was investigated in female patients with connective tissue disease and Raynaud's phenomenon using a questionnaire. Sixteen out of the 63 patients with systemic sclerosis had been exposed to solvents. A borderline significance was demonstrated compared to matched female controls (P < 0....

journal_title：Clinical rheumatology

authors： Czirják L,Kumánovics G

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:To evaluate sexual function in Tunisian women with rheumatoid arthritis (RA) and to compare it with that in voluntary healthy controls. METHODS:We conducted a cross-sectional study including 71 women with a confirmed diagnosis of RA according to the American College of Rheumatology/European League Against R...

journal_title：Clinical rheumatology

authors： Alia F,Rim BS,Miladi S,Ouenniche K,Kassab S,Chekili S,Zakraoui L,Abdelghani KB,Laatar A

更新日期：2019-12-01 00:00:00

abstract：:Our objective was to assess the progression of osteoarthritis (OA) using scoring systems based on the anatomical changes recorded in the finger joints on standard radiographs and to test how far these scoring systems could be used to evaluate the effects of candidate "disease modifying osteoarthritis drugs" (DMOAD). T...

journal_title：Clinical rheumatology

authors： Verbruggen G,Goemaere S,Veys EM

更新日期：2002-06-01 00:00:00

abstract：:The aim of this study was to investigate the association between the polymorphism of transporters associated with antigen processing ( TAP1/TAP2) genes and rheumatoid arthritis in Chinese patients. A total of 100 RA patients and 99 healthy control subjects were enrolled. Analyses with polymerase chain reaction (PCR) b...

journal_title：Clinical rheumatology

authors： Yu MC,Huang CM,Wu MC,Wu JY,Tsai FJ

更新日期：2004-02-01 00:00:00

abstract：:Behcet's disease (BD) is a multisystemic disorder characterised by recurrent oral and genital ulcers. Vasculitis and thrombotic events are the most important causes of mortality. Thrombosis is the major clinical finding in patients with BD, but the cause of the thrombosis is still unclear. Thromboelastography is an al...

journal_title：Clinical rheumatology

authors： Yaşar Bilge NŞ,Akay OM,Kaşifoğlu T,Kuş G,Korkmaz C

更新日期：2013-12-01 00:00:00

abstract：:The study aimed to determine the serum level of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) in patients with rheumatoid arthritis (RA) and investigate its clinical significance. GITRL levels were measured by enzyme-linked immunosorbent assay (ELISA) in 88 RA patients, 20...

journal_title：Clinical rheumatology

authors： Li L,Wen W,Jia R,Li Y,Liu X,Sun X,Li Z

更新日期：2016-09-01 00:00:00

abstract：:This cross-sectional investigation examined the prevalence and severity of dysphonia, globus pharyngeus, and dysphagia in patients affected by immunomediated (IM) diseases. Seventy subjects were administered the Voice Handicap Index (VHI) (scale 0-4), Glasgow-Edinburgh Throat Scale (GETS) (scale from 0 to 7) for globu...

journal_title：Clinical rheumatology

authors： Galli J,Marchese MR,De Canio C,Di Salvo M,Olivieri I,Santandrea L,Paludetti G

更新日期：2019-01-01 00:00:00

abstract：:The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration < 2 years) with forced vit...

journal_title：Clinical rheumatology

authors： Pavlov-Dolijanovic S,Vujasinovic Stupar N,Zugic V,Ostojic P,Zekovic A,Zivanovic Radnic T,Jeremic I,Tadic I

更新日期：2018-11-01 00:00:00

abstract：:Psoriatic arthritis (PsA) is a chronic T cell-mediated inflammatory spondyloarthropathy affecting 10-40 % of psoriasis (PSO) patients (0.3-1.0 % of the general population). Recent epidemiological studies have shown an increased prevalence of cardiovascular (CV) risk factors and/or morbidity among PSO or PsA patients a...

journal_title：Clinical rheumatology

authors： Khraishi M,Aslanov R,Rampakakis E,Pollock C,Sampalis JS

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To explore the link between ultrasonographic features of dactylitis in psoriatic arthritis (PsA) and symptoms, digital tenderness and duration of dactylitis. METHODS:Forty-eight cases of PsA dactylitis were investigated using high frequency ultrasound (US) both in grey scale (GS) and Power Doppler (PD), eva...

journal_title：Clinical rheumatology

authors： Girolimetto N,Costa L,Mancarella L,Addimanda O,Bottiglieri P,Santelli F,Meliconi R,Peluso R,Del Puente A,Macchioni P,Salvarani C,McGonagle D,Scarpa R,Caso F

更新日期：2019-03-01 00:00:00

abstract：:The use of biotechnology-derived medicines has significantly increased in recent decades. Although biosimilars undergo rigorous characterization as well as clinical studies to document their safety and effectiveness, they are highly complex molecules and small changes in the purification and production process of a bi...

journal_title：Clinical rheumatology

authors： Pineda C,Caballero-Uribe CV,de Oliveira MG,Lipszyc PS,Lopez JJ,Mataos Moreira MM,Azevedo VF

更新日期：2015-04-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is the most common inherited periodic fever syndrome characterized by recurrent episodes of serositis. Recently, a few studies have suggested that FMF is related to increased risk of atherosclerosis. Mean platelet volume (MPV) is a marker of platelet activation. Larger platelets are ...

journal_title：Clinical rheumatology

authors： Makay B,Türkyilmaz Z,Unsal E

更新日期：2009-08-01 00:00:00

abstract：:Melorheostosis is a very rare bone disease of unknown etiology characterised by linear hyperostosis and associated with fibrosis of soft tissues and the skin. This uncommon sclerosing bone dysplasia was first described by Leri and Joanny in 1922, and since then, until 1993, approximately 300 cases were reported in the...

journal_title：Clinical rheumatology

authors： Birtane M,Eryavuz M,Unalan H,Tüzün F

更新日期：1998-01-01 00:00:00

abstract：:Idiopathic paroxysmal rhabdomyolysis indicating a classical triad of symptoms consisting of muscle pain, weakness, and discolored urine is known as "Meyer-Betz syndrome". It may result in acute renal failure due to precipitation of the myoglobin casts in the tubuli or to the direct toxic effects of myoglobin to the tu...

journal_title：Clinical rheumatology

authors： Kasap B,Soylu A,Türkmen M,Kavukcu S

更新日期：2006-11-01 00:00:00

abstract：:We describe a 24-year old Caucasian man with gangrene of small bowels and intestinal resection due to mesenteric inflammatory veno-occlusive disease (MIVOD) who later developed deep vein thrombosis in his left leg. He had no clinical evidence of an underlying symptomatic connective tissue disease or Behçet's disease. ...

journal_title：Clinical rheumatology

authors： Gül A,Inanç M,Ocal L,Koniçe M,Aral O,Lie JT

更新日期：1996-03-01 00:00:00

abstract：:Atherosclerosis has been shown to be increased in chronic inflammatory diseases including ankylosing spondylitis (AS). Impaired endothelial function, the first step in atherosclerosis, may be reflected by changes in various endothelial biomarkers of hemostasis and the release of several cellular adhesion molecules or ...

journal_title：Clinical rheumatology

authors： Taylan A,Sari I,Kozaci DL,Yildiz Y,Bilge S,Coker I,Maltas S,Gunay N,Akkoc N

更新日期：2012-01-01 00:00:00

abstract：:Coexistence of rheumatoid arthritis and gout is considered to be unusual. The current study was designed as a population-based cross-sectional study, utilizing the medical database of Clalit Health Services, the largest healthcare provider organization in Israel. Data of adult patients who were previously diagnosed wi...

journal_title：Clinical rheumatology

authors： Merdler-Rabinowicz R,Tiosano S,Comaneshter D,Cohen AD,Amital H

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Our aim was to investigate the prevalence value of a high-avidity antinuclear antibody (ANA) of the IgG isotype (HA IgG ANA) compared with that of ANAs of other isotypes in patients with systemic lupus erythematosus (SLE) and to assess the associations of HA IgG ANA with the activity of SLE and lupus nephrit...

journal_title：Clinical rheumatology

authors： Zeng Y,Lin Y,Wang X,Zhang Y,Peng F,Wang J,Jiang L,Liang S,Xiao Y

更新日期：2020-09-01 00:00:00

abstract：:Takayasu's arteritis (TA) is a rare vasculitis that affects the aorta and its primary branches. Heterogeneous clinical manifestations have been described in different geographical areas. We aimed to evaluate demographic, clinical, and angiographic features and the outcome in 16 TA patients who were followed in a singl...

journal_title：Clinical rheumatology

authors： Petrovic-Rackov L,Pejnovic N,Jevtic M,Damjanov N

更新日期：2009-02-01 00:00:00

abstract：:Atherosclerosis plays a key role in cardiovascular disease in patients with rheumatoid arthritis (RA). Although therapy with TNF-alpha antagonists has resulted in dramatic improvement in the prognosis of RA, its effects on circulatory lipids are unclear. We conducted a systematic review of the literature to summarize ...

journal_title：Clinical rheumatology

authors： Pollono EN,Lopez-Olivo MA,Lopez JA,Suarez-Almazor ME

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Tumor necrosis factor inhibitors (anti-TNF) have become the standard treatment for rheumatoid arthritis (RA). However, evidence is inconsistent as to whether RA patients with anti-TNF are associated with an increased risk of non-melanoma skin cancer (NMSC) compared with those without anti-TNF. We performed a ...

journal_title：Clinical rheumatology

authors： Wang JL,Yin WJ,Zhou LY,Zhou G,Liu K,Hu C,Zuo XC,Wang YF

更新日期：2020-03-01 00:00:00