Intracellular signal transduction in proliferation of synovial cells.

abstract：:Melorheostosis is a very rare bone disease of unknown etiology characterised by linear hyperostosis and associated with fibrosis of soft tissues and the skin. This uncommon sclerosing bone dysplasia was first described by Leri and Joanny in 1922, and since then, until 1993, approximately 300 cases were reported in the...

journal_title：Clinical rheumatology

authors： Birtane M,Eryavuz M,Unalan H,Tüzün F

更新日期：1998-01-01 00:00:00

abstract：:Behçet's disease is a multisystem disorder affecting the skin, mucous membranes, eye, joints, central nervous system, and blood vessels. One of the known vascular complications of Behçet's disease is venous thrombosis or aneurysm formation. We report, herewith, a patient with Behçet's disease who developed radial arte...

journal_title：Clinical rheumatology

authors： el-Asrar AM,al-Momen AK,Alamro SA,Gader AG,Tabbara KF

更新日期：1996-09-01 00:00:00

abstract：:We present a patient with previously diagnosed hypocomplementemic urticarial vasculitis syndrome, with skin, lung, and renal involvement, who presented with congestive cardiac failure. During the course of her hospitalization, she was also found to have profound proximal muscle weakness in both upper and lower limbs a...

journal_title：Clinical rheumatology

authors： Chew GY,Gatenby PA

更新日期：2007-08-01 00:00:00

abstract：:We and others have previously shown that IL-17 is elevated in the synovial fluid of patients with reactive arthritis (ReA)/undifferentiated spondyloarthropathy (uSpA) having acute synovitis. Major source for IL-17 is Th17 cells, which differentiate from Th0 cells under the influence of TGF-β and IL-6, IL1-β and are ma...

journal_title：Clinical rheumatology

authors： Singh AK,Misra R,Aggarwal A

更新日期：2011-06-01 00:00:00

abstract：:Acetabular protrusion (PA) as measured by a line crossing method was studied in 73 patients with juvenile rheumatoid arthritis (JRA) and its frequency found to be 12% (9/73), presenting bilaterally in 5 cases and unilaterally in 4. All patients had some other forms of radiological damage and the presence of PA was pre...

journal_title：Clinical rheumatology

authors： Gusis SE,Maldonado Cocco JA,Rivero EM,Babini JC,Gagliardi SA

更新日期：1993-03-01 00:00:00

abstract：:We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously. ...

journal_title：Clinical rheumatology

authors： Armstrong D,Wright S,McVeigh C,Finch M

更新日期：2006-07-01 00:00:00

abstract：:The objective of this study is to identify baseline factors associated with rheumatoid arthritis (RA) diagnosis at the end of 1-year follow-up in a cohort of patients with very recent onset arthritis. Incident cases with self-reported arthritis (

journal_title：Clinical rheumatology

authors： Rojas-Serrano J,Burgos-Vargas R,Pérez LL,García CG,Moctezuma F,Vázquez-Mellado J

更新日期：2009-10-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:Primary Sjögren syndrome (pSS) is usually encountered between the fourth and sixth decades. It is known that the age of onset in autoimmune diseases may affect the clinical features. In this study, we aimed to investigate the clinical and laboratory characteristics of early onset pSS patients. ...

journal_title：Clinical rheumatology

authors： Yayla ME,Karaman Z,Torgutalp M,Keleşoğlu Dinçer AB,Aydemir Gülöksüz EG,Sezer S,Şahin Eroğlu D,Yüksel ML,Turgay TM,Kınıklı G,Ateş A

更新日期：2020-09-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) has often been regarded as the adult spectrum of systemic juvenile idiopathic arthritis (sJIA). The present study aims to compare the clinical and laboratory features, the disease course and the response to treatment in patients having AOSD with those having sJIA. Retrospective revie...

journal_title：Clinical rheumatology

authors： Pay S,Türkçapar N,Kalyoncu M,Simşek I,Beyan E,Ertenli I,Oztürk MA,Düzgün N,Erdem H,Ozbalkan Z,Kiraz S,Kinikli G,Besbas N,Dinç A,Ateş A,Olmez U,Calgüneri M,Aydintuğ OT,Bakkaloğlu A,Turan M,Turgay M,Karaaslan Y,

更新日期：2006-09-01 00:00:00

abstract：:The burden of anxiety in patients with systemic lupus erythematosus (SLE) compared to those with other inflammatory rheumatological conditions is unclear. We aimed to compare the frequency and level of anxiety between patients with SLE, rheumatoid arthritis (RA), and gout and healthy individuals and explore independen...

journal_title：Clinical rheumatology

authors： Mak A,Tang CS,Chan MF,Cheak AA,Ho RC

更新日期：2011-06-01 00:00:00

abstract：:The acute renal side-effects of nonsteroidal anti-inflammatory drugs are well documented. These include interstitial nephritis, hyperkalaemia, renal tubular acidosis, fluid retention, hypertension and nephrotic syndrome. The long-term effects are less well known. We have carried out a cross-sectional survey of an unse...

journal_title：Clinical rheumatology

authors： Richards IM,Fraser SM,Capell HA,Fox JG,Boulton-Jones JM

更新日期：1988-06-01 00:00:00

abstract：:The "A disintegrin and metalloprotease" (ADAM) family is thought to play an important role in tissue destruction and inflammatory reactions. ADAM-17 was first described as the protease responsible for tumor necrosis factor (TNF)-α shedding. Here, we have shown the expression of ADAM-17 in inflammatory myopathy and dem...

journal_title：Clinical rheumatology

authors： Nishimi A,Isozaki T,Nishimi S,Ishii S,Tokunaga T,Furuya H,Wakabayashi K,Kasama T

更新日期：2018-04-01 00:00:00

abstract：:The objective of the study was to analyze the impact of TNF antagonists (TNFa) on the total cholesterol and triglycerides on ankylosing spondylitis (AS) and psoriatic arthritis (PsA). In this single-centre observational study of AS and PsA patients, differences in triglyceride and total cholesterol levels and frequenc...

journal_title：Clinical rheumatology

authors： Maneiro JR,Souto A,Gomez-Reino JJ

更新日期：2017-05-01 00:00:00

abstract：:The most widely used noninvasive methods of bone mass measurement include: single photon absorptiometry (SPA), quantitative computed tomography (QCT), dual photon absorptiometry (DPA and DEXA). SPA is used to measure bone mineral content (BMC) of the distal radius. Its advantages are low cost and high precision in viv...

journal_title：Clinical rheumatology

authors： Sabatier JP,Guaydier-Souquieres G

更新日期：1989-06-01 00:00:00

abstract：:This study aims to measure the frequency of medication error (ME) in rheumatology outpatients of the Social Security System (SS) in Mexico and to measure the costs by comparing the days lost at work as direct consequence of the medication error against the theoretical cost of no error in the process. A prospective 6-m...

journal_title：Clinical rheumatology

authors： Aceves-Avila FJ,Benites-Godínez V,Ramos-Remus C

更新日期：2011-11-01 00:00:00

abstract：:In 1960 Rabinowitz and Dameshek emphasized the close relationship between idiopathic thrombocytopenic purpura (ITP) and systemic lupus erythematosus (SLE) and suggested that ITP is often a prodrome of SLE. On the basis of tis observation, the present study was designed to investigate the prevalence of SLE in patients ...

journal_title：Clinical rheumatology

authors： Lavalle C,Hurtado R,Quezada JJ,Cabral A,Fraga A

更新日期：1983-09-01 00:00:00

abstract：INTRODUCTION:We investigated whether rheumatoid arthritis (RA)-related autoantibodies were associated with abnormalities on pulmonary function tests (PFTs). METHODS:We studied RA serostatus and PFT abnormalities within a RA registry. RA serostatus was assessed by research assays for cyclic citrullinated peptide (CCP) ...

journal_title：Clinical rheumatology

authors： Huang S,He X,Doyle TJ,Zaccardelli A,Marshall AA,Friedlander HM,Blaustein RB,Smith EA,Cui J,Iannaccone CK,Mahmoud TG,Weinblatt ME,Dellaripa PF,Shadick NA,Sparks JA

更新日期：2019-12-01 00:00:00

abstract：:The aim of the study was to assess the eventual presence, cellular localization and extent of expression of the osteoclast activating cytokine M-CSF (CSF-1) in the periprosthetic tissues around loose total hip replacement (THR). Synovial-like membrane was obtained from the implant-to-bone interface and pseudocapsule f...

journal_title：Clinical rheumatology

authors： Xu JW,Konttinen YT,Waris V,Pätiälä H,Sorsa T,Santavirta S

更新日期：1997-05-01 00:00:00

abstract：:In sera of patients with systemic lupus erythematosus (SLE) a wide variety of antibodies against nuclear antigens can be found, including antibodies to nucleic acids, histones and non-histone nuclear proteins. Among these, antibodies to double stranded DNA (dsDNA) appear to be mainly restricted to SLE. Yet, in daily p...

journal_title：Clinical rheumatology

authors： Swaak T,Smeenk R

更新日期：1987-06-01 00:00:00

abstract：:Although mesenteric vasculitis due to Henoch-Schönlein purpura (HSP) is relatively uncommon, it is the most life-threatening manifestation associated with high mortality. We describe a 15-year-old boy with HSP who had massive gastrointestinal bleeding and ileus but delayed onset of the purpuric rash. Abdominal ultraso...

journal_title：Clinical rheumatology

authors： Wang L,Huang FC,Ko SF,Cheng MT

更新日期：2003-05-01 00:00:00

abstract：:This study aims to compare the mean platelet volume (MPV) levels in children and adults diagnosed with familial Mediterranean fever (FMF) during attack-free periods in order to find out whether it reflects the emergence of microalbuminuria/proteinuria and the development of amyloidosis or not. The study consisted of 6...

journal_title：Clinical rheumatology

authors： Sakallı H,Kal O

更新日期：2013-08-01 00:00:00

abstract：:Cytokine gene loci are one of the potential susceptibility factors in immuno-inflammatory diseases. Interleukin1 (IL-1) is a major monocyte derived proinflammatory cytokine that mediates tissue damage and cartilage loss in chronic arthritis. IL-1 locus has been linked to various autoimmune diseases, but data on juveni...

journal_title：Clinical rheumatology

authors： Aggarwal A,Srivastava R,Singh S,Kumar Dubey P

更新日期：2012-04-01 00:00:00

abstract：:Two cases of Paget's sarcoma of bone are described. The first one is mainly characterized by the almost simultaneous degeneration of the only two existing locations of the underlying Paget's disease. The second case is one of monostotic Paget's disease of the scapula disclosed by the malignant degeneration. ...

journal_title：Clinical rheumatology

authors： Huaux JP,Esselinckx W,Noel H,Grodos J,Nagant de Deuxchaisnes C

更新日期：1984-12-01 00:00:00

abstract：:Fifty-two patients with psoriatic arthritis (PA), treated with auranofin (AF), were entered into a one year prospective, open study. The total group showed a significant increase in frequency of HLA antigens A1 and B38, and a reduction of B5 when compared to healthy controls. There was a remission or an important impr...

journal_title：Clinical rheumatology

authors： Salvarani C,Zizzi F,Macchioni P,Mantovani W,Rossi F,Baricchi R,Bellelli A,Capozzoli N,Frizziero L,Portioli I

更新日期：1989-03-01 00:00:00

abstract：:HLA B27 and other clinical findings were investigated in 18 Turkish patients with Reiter's syndrome (mean age 35.8 +/- 8.09). Male/female ratio was 2/1. All 18 patients were seronegative, 12 (66.6%) presenting with an asymmetrical oligoarticular arthritis. Radiological sacroiliitis and enthesopathy was found in 9 (50%...

journal_title：Clinical rheumatology

authors： Tuncer T,Arman MI,Akyokus A,Bütün B,Unal S

更新日期：1992-06-01 00:00:00

abstract：:The aim of this study was to evaluate clinical remission and MDA in PsA patients who started TNF-inhibitors (TNFi) treatment with a 2-year follow-up. Concomitant therapies as well as comorbidities were assessed. Level of concordance of clinimetric indices and the potential predictive factors of remission/MDA were also...

journal_title：Clinical rheumatology

authors： Chimenti MS,Triggianese P,Conigliaro P,Tonelli M,Gigliucci G,Novelli L,Teoli M,Perricone R

更新日期：2017-10-01 00:00:00

abstract：:The levels of 63 cytokines, chemokines, and growth factors were measured in the serum of four patients with idiopathic morphea and of one patient with vitamin K1-induced morphea employing a multiplex assay to identify the role of inflammatory/immunologic events in their pathogenesis. Full-thickness skin biopsies of af...

journal_title：Clinical rheumatology

authors： Cox LA,Webster GF,Piera-Velazquez S,Jimenez SA

更新日期：2017-05-01 00:00:00

abstract：:The objective of this study was to analyze the clinical, laboratorial, and therapeutical response of polymyalgia rheumatica (PMR) to anti-tumor necrosis factor (anti-TNF) treatment. We systematically searched English articles on the subjects of PMR who were treated with TNF blockers in Pubmed from 1994 to 2010. In add...

journal_title：Clinical rheumatology

authors： Aikawa NE,Pereira RM,Lage L,Bonfá E,Carvalho JF

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to analyze the prevalence of myositis-specific autoantibodies (MSAs) and to elucidate their associations with clinical features in Chinese patients with polymyositis (PM) and dermatomyositis (DM). METHODS:Twelve subsets of MSAs including anti-Mi-2, anti-TIF1-γ, anti-MDA5, anti-NXP2,...

journal_title：Clinical rheumatology

authors： Li S,Ge Y,Yang H,Wang T,Zheng X,Peng Q,Lu X,Wang G

更新日期：2019-08-01 00:00:00

abstract：:Chronic pediatric musculoskeletal (MSK) conditions are a major cause of morbidity. The burden of pediatric rheumatic diseases in East Africa is largely unknown. The purposes of this study were to estimate frequencies and assess the spectrum of MSK-related diagnoses using ICD-10 diagnostic codes among outpatients at a ...

journal_title：Clinical rheumatology

authors： Scuccimarri R,Broten L,Migowa A,Ngwiri T,Wachira J,Bernatsky S,Hitchon C,Colmegna I

更新日期：2019-04-01 00:00:00