Abstract：
:In 1960 Rabinowitz and Dameshek emphasized the close relationship between idiopathic thrombocytopenic purpura (ITP) and systemic lupus erythematosus (SLE) and suggested that ITP is often a prodrome of SLE. On the basis of tis observation, the present study was designed to investigate the prevalence of SLE in patients with the initial diagnosis of ITP, autoimmune hemolytic anemia (AIHA), Fisher-Evans' syndrome (F-E) and idiopathic aplastic bone marrow (IABM) and to investigate the salient clinical manifestations and prognosis of these patients. We studied 62 patients, 35 with ITP, 16 with AIHA, 9 with F-E and 2 with IABM. Seventeen developed four or more ARA criteria for SLE within 6 of 14 years after the initial hematologic manfestations (IHM). Mucocutaneous symptoms predominated in all groups. None developed renal failure and only 2 had central nervous system involvement. When these patients were matched by age, sex and duration of illness with 24 SLE patients without hematologic abnormalities, the everity and therapeutic indices of the former showed a significantly (p 0.001) milder course. Eight of the 9 patients that required splenectomy are at present without treatment. SLE patient with IHM have a more benign course which is not worsened by splenectomy.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Lavalle C,Hurtado R,Quezada JJ,Cabral A,Fraga Adoi
10.1007/BF02041395subject
Has Abstractpub_date
1983-09-01 00:00:00pages
227-32issue
3eissn
0770-3198issn
1434-9949journal_volume
2pub_type
杂志文章abstract：INTRODUCTION:The frequency of eighth nerve lesions in patients with giant cell arteritis (GCA) has rarely been examined. However, sudden onset deafness has been recorded as a presenting feature of GCA on several occasions. This study sought to establish how common this and other symptoms of eighth nerve involvement are...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04747-3
更新日期：2019-12-01 00:00:00
abstract：:This study aimed to determine the frequency of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) antibodies in a cohort of patients with palindromic rheumatism (PR) and to find determinants for progression to rheumatoid arthritis (RA). All new cases of PR (n=90) were included prospectively and followed up ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2569-3
更新日期：2014-06-01 00:00:00
abstract：:This study aims to characterize the clinical features of a cohort of patients diagnosed with systemic sclerosis (SSc) after the age of 75 and compare them to a group diagnosed at a younger age. We record the review of 769 patients diagnosed with SSc over the past 16 years. Utilizing a nested case-control model, we com...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-0177-y
更新日期：2006-11-01 00:00:00
abstract：:Because the pathophysiology of knee osteoarthritis is poorly understood, optimal evidence-based clinical management is uncertain. Sibling comparison studies can help inform a clinical model to guide preventive care. We compared the 8-year clinical outcomes in 2 sisters with a family history of osteoarthritis, normal B...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-020-05181-6
更新日期：2020-10-01 00:00:00
abstract：:HLA B27 and other clinical findings were investigated in 18 Turkish patients with Reiter's syndrome (mean age 35.8 +/- 8.09). Male/female ratio was 2/1. All 18 patients were seronegative, 12 (66.6%) presenting with an asymmetrical oligoarticular arthritis. Radiological sacroiliitis and enthesopathy was found in 9 (50%...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207965
更新日期：1992-06-01 00:00:00
abstract：:The first name of the co-author of the above article was presented incorrect in the published version. The author name "Miangliang Qiu" should read "Mingliang Qiu" as mentioned above. ...
journal_title：Clinical rheumatology
pub_type： 已发布勘误
doi：10.1007/s10067-020-04943-6
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:To identify factors associated with active tuberculosis (TB) in patients with systemic lupus erythematosus (SLE). METHODS:We performed a retrospective case-control study in two tertiary care teaching hospitals in Medellín, Colombia. From January 2007 to December 2017, a total of 268 patients with SLE were in...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05225-x
更新日期：2021-01-01 00:00:00
abstract：:Socio-economic gradients in occurrence of diseases have been reported for many chronic conditions. However, whether the magnitude of socio-economic gradients differs across diseases and the extent to which lifestyle mediates such relationships are not known. Cross-sectional data from The National Monitor on Musculoske...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4158-3
更新日期：2018-12-01 00:00:00
abstract：:We investigated the occurrence of an active cytomegalovirus (CMV) infection in patients with polyarteritis nodosa (PAN). Eleven patients with PAN were screened for the presence of CMV-DNA in their blood using the polymerase chain reaction (PCR). Serum anti-CMV IgG and anti-CMV IgM antibodies were determined by enzyme-...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670050148
更新日期：1999-01-01 00:00:00
abstract：:With the aim of evaluating the role of 1,25 dihydroxyvitamin D in the pathogenesis of osteoporosis, this hormone was studied in 90 subjects. They were divided into three groups: the first group consisted of 30 normal female subjects (aged 30 to 45); the second group comprised 30 elderly female subjects (aged 67 to 90)...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02031970
更新日期：1990-06-01 00:00:00
abstract：:This article is a small case series that aims to discuss the impact of depression, vascular, and fibrotic changes on development of erectile dysfunction (ED) in patients with systemic sclerosis (SSc). In this paper, we present five male patients with SSc, aged 30-48 years. All patients are nonsmokers, and their past m...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0567-4
更新日期：2007-10-01 00:00:00
abstract：:Chronic hepatitis C virus (HCV) viremia has been known to provoke a plethora of autoimmune syndromes referred to as extrahepatic manifestations of chronic HCV infection. Aim of the current study was to assess the prevalence of rheumatologic manifestations among Egyptians with hepatitis C infection and its' association...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1463-x
更新日期：2010-12-01 00:00:00
abstract：:In juvenile chronic arthritis (JCA) the indices of disease activity, such as joint swelling, pain, tenderness, and limitation of motion, may poorly correlate with the degree of functional impairment. Since the improvement of functional capacity is one of the main objectives of treatment, we evaluated the effect of met...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02208347
更新日期：1995-05-01 00:00:00
abstract：:The original version of this article was revised due to a retrospective Open Access order. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10067-020-05278-y
更新日期：2020-10-01 00:00:00
abstract：:The effect of long-term (18-70 months) chloroquine treatment 250 mg daily, in rheumatoid arthritis (RA) was studied in 20 patients. Sedimentation rates were significantly reduced, as compared to a reference group of 10 RA patients on no treatment of disease modifying anti-rheumatic drugs. Radiographical progression of...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02041561
更新日期：1983-12-01 00:00:00
abstract：:Until recently, renal crisis was the most significant cause of morbidity and mortality in patients with scleroderma (SSc). Nowadays, following the introduction of angiotensin-converting enzyme inhibitors used in renovascular hypertension, pulmonary fibrosis and pulmonary hypertension have become the most common causes...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章
doi：10.1007/s100670050138
更新日期：1999-01-01 00:00:00
abstract：:A pair of identical twins suffering from ankylosing spondylitis is reported. One brother developed an earlier-onset disease and showed ossification of the posterior longitudinal ligament and the flavum ligament in his cervical spine. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02249033
更新日期：1994-06-01 00:00:00
abstract：:Haemorrhoidal disease (HD) is one of the most common diseases encountered by the clinicians of general surgery. Chronic constipation, pushing during defecation and increased abdominal pressure play an important role in development of haemorrhoidal disease. Patients with ankylosing spondylitis (AS) frequently use the V...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2732-x
更新日期：2015-03-01 00:00:00
abstract：:Infection is a major cause of morbidity and mortality among patients with systemic lupus erythematosus (SLE). To describe the pattern of serious infections in patients with SLE and to identify the predictors of infection-related mortality among SLE patients with serious infections, we prospectively studied all SLE pat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4102-6
更新日期：2018-08-01 00:00:00
abstract：:Matrix metalloproteinases (MMPs) are the key enzymes responsible for the joint destruction. Their activity is regulated by the level of proinflammatory cytokines. The aim of this study was to examine the impact of TNF-α G-308A polymorphism on MMP-9 levels in blood plasma (BP) and synovial fluid (SF) of patients with r...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3699-1
更新日期：2017-07-01 00:00:00
abstract：:We investigated the all-inclusive echocardiographic features in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) within 3 months before and after diagnosis. We reviewed the medical records of 89 AAV patients taking echocardiography and 35 age- and gender-matched controls. We collect...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3868-2
更新日期：2017-12-01 00:00:00
abstract：:Four patients with rheumatoid nodulosis are here described, together with a review of cases reported to date in the literature. This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign cour...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207201
更新日期：1992-09-01 00:00:00
abstract：:Adult-onset Still's disease (AOSD) is a rare disorder of unknown aetiology, characterised by high spiking fever, an evanescent, erythematous, maculopapular rash, arthralgia or arthritis, lymphadenopathy, hepatosplenomegaly, sore throat and serositis. It is associated with marked leukocytosis, high erythrocyte sediment...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670070034
更新日期：2000-01-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent self-limited attacks of fever and polyserositis. Reactive amyloid A amyloidosis is the most devastating complication of FMF, and amyloidosis continues to occur in the colchicine era in untreated and noncompliant patients. U...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-012-2009-1
更新日期：2012-08-01 00:00:00
abstract：:To measure serum soluble transferrin receptor (s-TfR) levels in patients with rheumatoid arthritis (RA), sera were obtained from 50 Japanese RA patients and 20 healthy subjects. Both s-TfR and serum erythropoietin (EPO) levels were measured by enzyme-linked immunosorbent assay (ELISA). Routine laboratory tests were al...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章
doi：10.1007/s100670170018
更新日期：2001-01-01 00:00:00
abstract：:To determine serum interleukin-33 (IL-33) levels and their associations with clinical parameters in patients with systemic sclerosis (SSc). Serum IL-33 levels were examined by enzyme-linked immunosorbent assay in 69 patients with SSc and 30 healthy individuals. In a retrospective longitudinal study, sera from 14 patie...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1686-5
更新日期：2011-06-01 00:00:00
abstract：:Mycophenolate mofetil (MMf) has recently been reported as a useful alternative immunosuppressive drug in autoimmune diseases. There is paucity of literature on its use in Takayasu's arteritis (TA). The aim of this study was to assess the safety and efficacy of MMf in Asian Indian patients with Takayasu's arteritis. Re...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1333-6
更新日期：2010-03-01 00:00:00
abstract：:This study aims to measure the frequency of medication error (ME) in rheumatology outpatients of the Social Security System (SS) in Mexico and to measure the costs by comparing the days lost at work as direct consequence of the medication error against the theoretical cost of no error in the process. A prospective 6-m...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1837-8
更新日期：2011-11-01 00:00:00
abstract：INTRODUCTION:Antibody against cyclic citrullinated protein (ACPA) is counted as one of the most important biomarkers in diagnosis, classification, and prognosis of rheumatoid arthritis (RA). We examined the evolution of ACPA during disease course and assess predictive value of time-weighted cumulative ACPA titer on rad...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04554-w
更新日期：2019-09-01 00:00:00
abstract：:The relations between parameters obtained by clinical absorptiometric techniques, such as SPA, DPA, DXA and QCT, and geometrical and material parameters of bone structures are investigated. Two types of bone are considered: the diaphysis of a long bone, modelled as a hollow cylindrical structure consisting of compact ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：
更新日期：1994-12-01 00:00:00
