Comparison of 8-year knee osteoarthritis progression in 2 siblings: a case-based review.

Abstract:

:Because the pathophysiology of knee osteoarthritis is poorly understood, optimal evidence-based clinical management is uncertain. Sibling comparison studies can help inform a clinical model to guide preventive care. We compared the 8-year clinical outcomes in 2 sisters with a family history of osteoarthritis, normal BMI, and absence of knee pain at baseline. Both patients had Kellgren-Lawrence grade 1 in the affected knee at the time of twisting knee injuries leading to osteoarthritis diagnoses at age 50 (patient 1) and 51 (patient 2). Patient 1 developed a chronic right knee effusion, and progressed to Kellgren-Lawrence grade 3 bilaterally by the time she had a right total knee replacement at age 58. Patient 2 had subchondral fractures of the right knee with transient effusion, which healed after 1 year of partial weight-bearing with crutches and subsequent daily use of knee sleeves. Patient 2 had Kellgren-Lawrence grade 0 bilaterally upon surveillance imaging at age 58. The terms "osteoarthritis and knee and diagnostic imaging and subchondral bone and pathophysiology" were searched in the PubMed database to identify original research articles to inform a clinical model consistent with the patients' outcomes. A fluid model of osteoarthritis was the best explanatory model for the discordant clinical trajectories of the age-matched siblings. Patient recommendations are presented based on these findings.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Gourlay ML,Gourlay LL

doi

10.1007/s10067-020-05181-6

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

3105-3113

issue

10

eissn

0770-3198

issn

1434-9949

pii

10.1007/s10067-020-05181-6

journal_volume

39

pub_type

杂志文章,评审
  • Microwave thermography as a noninvasive assessment of disease activity in inflammatory arthritis.

    abstract::Microwave thermography is the technique of measuring natural thermal radiation from body tissues of clinical interest. It is safe, requires no control of environmental conditions and exposes the patient to no ionising radiation. In this study, we found that microwave thermography of the knee joints showed weak correla...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02242999

    authors: MacDonald AG,Land DV,Sturrock RD

    更新日期:1994-12-01 00:00:00

  • Treatment of osteoporosis in renal insufficiency.

    abstract::Patients with osteoporosis often have chronic kidney disease (CKD). CKD is associated with bone and mineral disturbances, renal osteodystrophy, which like osteoporosis leads to a higher risk of fractures. Bisphosphonates are first-line therapy for osteoporosis; however, these are contra-indicated in patients with a GF...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-015-2883-4

    authors: Schipper LG,Fleuren HW,van den Bergh JP,Meinardi JR,Veldman BA,Kramers C

    更新日期:2015-08-01 00:00:00

  • CD4+ and CD8+ subsets: naive and memory cells in the peripheral blood of patients with systemic sclerosis.

    abstract::Systemic Sclerosis (SSc; scleroderma) is associated with several immunological abnormalities, including altered proportion between lymphocyte subsets. Peripheral blood lymphocyte subsets from 25 patients with SSc were studied by two-colour flow cytometry using monoclonal antibodies against CD45RA and CD29 markers, whi...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02229871

    authors: Gorla R,Airò P,Malagoli A,Carella G,Prati E,Brugnoni D,Franceschini F,Cattaneo R

    更新日期:1994-03-01 00:00:00

  • The Social Gap Index and the prevalence of osteoarthritis in the community: a cross-sectional multilevel study in Mexico.

    abstract::Multilevel studies have gained importance for highlighting social inequalities in health. These associations have been reported previously in diseases such as arthritis and chronic pain. We conducted a cross-sectional study using multilevel analysis to identify individual and contextual factors associated with the var...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-014-2776-y

    authors: Rodriguez-Amado J,Moreno-Montoya J,Alvarez-Nemegyei J,Goycochea-Robles MV,Sanin LH,Burgos-Vargas R,Cardiel MH,Garza-Elizondo MA,Maradiaga M,Pelaez-Ballestas I,GEEMA.

    更新日期:2016-01-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus septic arthritis: urgent and emergent.

    abstract::A 71-year-old male rheumatoid patient presented with MRSA septic arthritis. The impact of this organism on musculoskeletal practice is discussed. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF01450904

    authors: Byrne PA,Hosein IK,Camilleri J

    更新日期:1998-01-01 00:00:00

  • Treatment of chronic tophaceous gout with a free flap.

    abstract::A 62-year-old man who suffered from severe deforming arthritis, secondary to chronic tophaceous gout with multilobular, solid, tender, enlarged subcutaneous nodules, and draining tophi in right second finger, was treated by free flap and finally got the more functional and aesthetic result. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-009-1321-x

    authors: Lee KS,Lee HS,Kim NG,Kim JS,Lee SI,Choi TH

    更新日期:2010-03-01 00:00:00

  • Correction to: Comparison of 8-year knee osteoarthritis progression in 2 siblings: a case-based review.

    abstract::The original version of this article was revised due to a retrospective Open Access order. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s10067-020-05278-y

    authors: Gourlay ML,Gourlay LL

    更新日期:2020-10-01 00:00:00

  • Assessment of inflammatory joint activity in rheumatoid arthritis and changes in atmospheric conditions.

    abstract::Seventy-nine patients suffering from rheumatoid factor positive rheumatoid arthritis (RA) were included in this study. In each patient disease activity was assessed three times at two-week intervals during a four-week period. All factors that might possibly influence RA, except atmospheric conditions (AC) were held co...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02206665

    authors: van de Laar MA,Bernelot Moens HJ,van der Stadt RJ,van der Korst JK

    更新日期:1991-12-01 00:00:00

  • Prevalence of cardiovascular risk factors in patients with psoriatic arthritis.

    abstract::Psoriatic arthritis (PsA) is a chronic T cell-mediated inflammatory spondyloarthropathy affecting 10-40 % of psoriasis (PSO) patients (0.3-1.0 % of the general population). Recent epidemiological studies have shown an increased prevalence of cardiovascular (CV) risk factors and/or morbidity among PSO or PsA patients a...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-014-2743-7

    authors: Khraishi M,Aslanov R,Rampakakis E,Pollock C,Sampalis JS

    更新日期:2014-01-01 00:00:00

  • Subacute cutaneous lupus erythematosus associated with Hodgkin's disease.

    abstract::Simultaneous occurrence of subacute cutaneous lupus erythematosus and malignancy has rarely been reported. We report the first case of subacute cutaneous lupus erythematosus associated with Hodgkin's disease. Although our case does not fulfill the criteria of paraneoplastic process, a relationship between the two diso...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02207938

    authors: Castanet J,Taillan B,Lacour JP,Garnier G,Perrin C,Ortonne JP

    更新日期:1995-11-01 00:00:00

  • The impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department.

    abstract:INTRODUCTION/OBJECTIVES:The primary objective was to evaluate the impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department. Secondary objectives were to determine (i) if medication history discrepancies were detected more frequently in the elderly or not, and (ii) if the...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-020-05138-9

    authors: Soubieux A,Chenailler C,Lattard C,Banse C,Kozyreff-Meurice M,Gondé H,Lequerré T,Vittecoq O,Varin R

    更新日期:2021-01-01 00:00:00

  • Phrasing of the patient global assessment in the rheumatoid arthritis ACR/EULAR remission criteria: an analysis of 967 patients from two databases of early and established rheumatoid arthritis patients.

    abstract::The ACR/EULAR Boolean remission criteria for rheumatoid arthritis (RA) include a strict cutoff for patient global assessment (PGA, value ≤ 1/10). Near-remission corresponds to remission for joint counts and C-reactive protein but with PGA > 1. The objective was to explore whether the contribution of PGA to remission a...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-018-3998-1

    authors: Gossec L,Kirwan JR,de Wit M,Balanescu A,Gaujoux-Viala C,Guillemin F,Rat AC,Saraux A,Fautrel B,Kvien TK,Dougados M,RAID investigators.

    更新日期:2018-06-01 00:00:00

  • The role of mannose-binding lectin in systemic lupus erythematosus.

    abstract::Susceptibility to systemic lupus erythematosus (SLE) is associated with genetic, hormonal, immunological, and environmental factors. Many genes have been related with the appearance of SLE, including several loci that code different complement components and their receptors. Some genetic deficiencies of complement mol...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-008-0838-8

    authors: Monticielo OA,Mucenic T,Xavier RM,Brenol JC,Chies JA

    更新日期:2008-04-01 00:00:00

  • Knee joint destruction driven by residual local symptoms after anti-tumor necrosis factor therapy in rheumatoid arthritis.

    abstract::In patients with rheumatoid arthritis who had symptomatic knee joints at the start of anti-tumor necrosis factor (TNF) therapy, the relationship between local symptoms and knee joint destruction at 94 weeks was retrospectively investigated. Among the patients with rheumatoid arthritis and received anti-TNF therapy, th...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-013-2181-y

    authors: Imagama T,Tanaka H,Tokushige A,Seki K,Sumiura S,Yamamoto M,Nagahiro Y,Taguchi T

    更新日期:2013-06-01 00:00:00

  • Chronic eosinophilic pneumonia associated with an initiation of rheumatoid arthritis.

    abstract::Although peripheral blood eosinophilia is observed in patients with active inflammatory rheumatoid arthritis (RA), RA is not a recognised cause of pulmonary eosinophilia. We describe a 55-year-old woman affected by chronic eosinophilic pneumonia (CEP) concomitantly with an initiation of RA. Both diseases responded rap...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-003-0703-8

    authors: Kwak JJ,Chang JE,Lee J,Cho YJ,Sung SH

    更新日期:2003-09-01 00:00:00

  • Microangiopathy and forearm arterial blood flow in systemic sclerosis: a controlled study.

    abstract:OBJECTIVE:The aim of the study was to evaluate the interrelationship between the micro- and macrovasculature. METHODS:This is a cross-sectional study that examined SSc patients and fibromyalgia (FM) patients as controls. We assessed forearm peripheral vascular status and nailfold capillaroscopy. We evaluated the assoc...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-020-05025-3

    authors: Bieber A,Dolnikov K,Chizik V,Novofastovsky I,Fawaz A,Balbir-Gurman A,Mader R

    更新日期:2020-09-01 00:00:00

  • Clinical characteristics of human brucellosis in patients with various monoarticular involvements.

    abstract::The aim of the study was to determine the main demographic, epidemiological, clinical characteristics, and outcome in patients with various types of brucellar monoarticular involvement. Retrospectively, we analyzed medical histories of 331 patients with brucellar monoarticular involvement who were treated at the infec...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-016-3207-z

    authors: Bosilkovski M,Zezoski M,Siskova D,Miskova S,Kotevska V,Labacevski N

    更新日期:2016-10-01 00:00:00

  • Hypofixation on bone scintigraphy in reflex sympathetic dystrophy syndrome.

    abstract::We report an adult case of reflex sympathetic dystrophy. In contrast to the usual findings in adults, three phase bone scintigraphy showed decreased bloodflow and bloodpool with hypofixation on delayed steady state bone scan of the affected lower limb. In spite of various therapeutic attempts severe dystrophy develope...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02208035

    authors: Williame LM,Sand A

    更新日期:1991-03-01 00:00:00

  • The labyrinth of autoinflammatory disorders: a snapshot on the activity of a third-level center in Italy.

    abstract::Autoinflammatory disorders (AIDs) are a novel class of diseases elicited by mutations in genes regulating the homeostasis of innate immune complexes, named inflammasomes, which lead to uncontrolled oversecretion of the proinflammatory cytokine interleukin-1β. Protean inflammatory symptoms are variably associated with ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-014-2721-0

    authors: Cantarini L,Vitale A,Lucherini OM,De Clemente C,Caso F,Costa L,Emmi G,Silvestri E,Magnotti F,Maggio MC,Prinzi E,Lopalco G,Frediani B,Cimaz R,Galeazzi M,Rigante D

    更新日期:2015-01-01 00:00:00

  • Potential and prognostic factor for belimumab-free remission in patients with systemic lupus erythematosus: a single-center retrospective analysis.

    abstract::Belimumab is an effective and safe treatment option for systemic lupus erythematosus (SLE). However, data on treatment cessation are lacking. Thus, we investigated belimumab-free remission in SLE patients. SLE patients receiving belimumab in our institute (May 1, 2013-May 31, 2019) were retrospectively identified usin...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-020-05052-0

    authors: Nakai T,Fukui S,Ikeda Y,Shimizu H,Tamaki H,Okada M

    更新日期:2020-12-01 00:00:00

  • Association between Takayasu arteritis and latent or active Mycobacterium tuberculosis infection: a systematic review.

    abstract::Takayasu arteritis (TA) is a granulomatous vasculitis of large vessels with unknown aetiopathogenesis. An association between TA and tuberculosis (TB) has been suggested by several authors. The objective of this study was to perform a systematic review of the literature on the association of Mycobacterium tuberculosis...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-019-04818-5

    authors: Pedreira ALS,Santiago MB

    更新日期:2020-04-01 00:00:00

  • The spectrum and clinical significance of myositis-specific autoantibodies in Chinese patients with idiopathic inflammatory myopathies.

    abstract:OBJECTIVES:The aim of this study is to analyze the prevalence of myositis-specific autoantibodies (MSAs) and to elucidate their associations with clinical features in Chinese patients with polymyositis (PM) and dermatomyositis (DM). METHODS:Twelve subsets of MSAs including anti-Mi-2, anti-TIF1-γ, anti-MDA5, anti-NXP2,...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-019-04503-7

    authors: Li S,Ge Y,Yang H,Wang T,Zheng X,Peng Q,Lu X,Wang G

    更新日期:2019-08-01 00:00:00

  • Computerized tomography, clinical and X-ray correlations in the hemisacralized fifth lumbar vertebra.

    abstract::One hundred and twenty patients with hemisacralization of the L5 vertebra associated with LBP underwent clinical, conventional X-ray and CT examinations. More than 50% of the patients had scoliosis. One third of the patients had disc lesions. Sacroiliac joint sclerosis was noted in two thirds of the cases. Almost all ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02054251

    authors: Avrahami E,Cohn DF,Yaron M

    更新日期:1986-09-01 00:00:00

  • Anaplastic large cell lymphoma in a patient with MAGIC syndrome: a case and review of the literature.

    abstract::Mouth and genital ulcer with inflamed cartilage syndrome (MAGIC syndrome) is a rare autoinflammatory disorder with unknown etiology. Except for the common clinical manifestations mimicking Behçet's disease and relapsing polychondritis, some other clinical entities are occasionally observed. In this report, we present ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-020-05384-x

    authors: Chen Z,Zhang S,Wang L,Fei Y,Shen M,Wu H,Liu J,Zheng W

    更新日期:2020-09-11 00:00:00

  • Correction to: Risk of adverse outcomes in patients with rheumatoid arthritis hospitalized for stroke-a cross-sectional study.

    abstract::The authors of the published version of this article incorrectly presented the affiliation of Li-Chin Sung. The revised affiliation is now presented correctly in this article. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s10067-019-04531-3

    authors: Kang JH,Xirasagar S,Lin HC,Kao PF,Sung LC

    更新日期:2019-05-01 00:00:00

  • A case of atypical giant cell arteritis diagnosed by positron emission tomography (PET).

    abstract::The authors describe an atypical case of a patient having giant cell arteritis presenting only with fever, diagnosed by positron emission tomography and subsequently confirmed by temporal artery biopsy. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-007-0831-7

    authors: Belloli L,Rodari M,Massarotti M,Conciato L,Chiti A,Marasini B

    更新日期:2008-06-01 00:00:00

  • Serum adropin level and ENHO gene expression in systemic sclerosis.

    abstract::Adropin, a secreted protein, is encoded by the energy homeostasis associated (ENHO) gene. It has been implicated in the several physiological and pathological processes such as angiogenesis and apoptosis. Therefore, the aim of present study was to investigate serum adropin levels and ENHO gene expressions in systemic ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-016-3266-1

    authors: Yolbas S,Kara M,Yilmaz M,Aydin S,Koca SS

    更新日期:2016-06-01 00:00:00

  • Pulmonary hypertension in primary Sjögren's syndrome: report of a case and review of the literature.

    abstract::A 61-year-old female with a history of vaginal dryness, Raynaud's phenomenon, xerostomia and xerophthalmia presented with exertional dyspnoea and weakness. Laboratory and instrumental examinations enabled us to make the diagnosis of primary Sjögren's syndrome, while cardiologic and imaging investigations evidenced iso...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-004-1071-8

    authors: Bertoni M,Niccoli L,Porciello G,Storri L,Nannini C,Manes A,Palazzini M,Galiè N,Cantini F

    更新日期:2005-08-01 00:00:00

  • Bone mass in Zaireans: radiogrammetric determination.

    abstract::Bone mass was measured in 230 subjects with ages ranging from 15 to 54 years (110 males and 120 females), using the radiogrammetric method on the second metacarpal bone. Results of the study show that bone mass increases with age up to 34 years and then decreases, both in males and females, although males have signifi...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02208090

    authors: Kabeya JM,Mbuyi Muamba JM,Tozin R,Dequeker J

    更新日期:1995-01-01 00:00:00

  • Fear of movement and avoidance behaviour toward physical activity in chronic-fatigue syndrome and fibromyalgia: state of the art and implications for clinical practice.

    abstract::Severe exacerbation of symptoms following physical activity is characteristic for chronic-fatigue syndrome (CFS) and fibromyalgia (FM). These exacerbations make it understandable for people with CFS and FM to develop fear of performing body movement or physical activity and consequently avoidance behaviour toward phys...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-013-2277-4

    authors: Nijs J,Roussel N,Van Oosterwijck J,De Kooning M,Ickmans K,Struyf F,Meeus M,Lundberg M

    更新日期:2013-08-01 00:00:00