Chloroquine in long-term treatment of rheumatoid arthritis.

abstract：:This study was designed to investigate the functional heterogeneity of human Th17 and how their plasticity shapes the nature of immune cell responses to inflammation and autoimmune diseases, such as systemic lupus erythematosus (SLE). We evaluated functional Th17 cell subsets based on the profile of cytokine productio...

journal_title：Clinical rheumatology

authors： Henriques A,Inês L,Pais ML,da Silva JA,Paiva AA

更新日期：2012-03-01 00:00:00

abstract：:The aims of this study were to find the characteristics and prevalence of nailfold capillary changes in a large series of patients with Behçet's disease (BD) and to analyze their possible relation to other clinical characteristics of the disease. We performed nailfold capillaroscopy in 128 randomly selected patients f...

journal_title：Clinical rheumatology

authors： Movasat A,Shahram F,Carreira PE,Nadji A,Akhlaghi M,Naderi N,Davatchi F

更新日期：2009-05-01 00:00:00

abstract：:We aimed to evaluate the presence of peripheral antineutrophil cytoplasmic antibodies (p-ANCA) and cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA) in children with SLE and to correlate its association of laboratory findings. Twenty-one children with SLE were studied. Serum samples in patients were tested by...

journal_title：Clinical rheumatology

authors： Bakkaloglu A,Topaloglu R,Saatçi U,Ozdemir S,Ozen S,Başsoy Y,Beşbaş N

更新日期：1998-01-01 00:00:00

abstract：:Chronic whiplash-associated disorders (WAD) remains a challenging condition for clinicians. There is substantial evidence for the presence of various cervical dysfunctions (e.g., increased cervical muscle tone and impaired cervical movement control), but their contribution to the complex clinical picture of subjects w...

journal_title：Clinical rheumatology

authors： Nijs J,Van Oosterwijck J,De Hertogh W

更新日期：2009-03-01 00:00:00

abstract：:Chorea is a rare complication of systemic lupus erythematosus (SLE) and is strongly related to the presence of antiphospholipid antibodies. Various infections may also be triggering factors in the development of choreiform movements. Additionally, Salmonella infection is the most common opportunistic bacterial infecti...

journal_title：Clinical rheumatology

authors： Lazurova I,Macejova Z,Benhatchi K,Oetterová M,Antolová E,Asherson RA,Rovensky J

更新日期：2007-12-01 00:00:00

abstract：:The aim of this study was to investigate generalized osteoarthritis (GOA) by combining X-ray grading of the knee, spine and hand using biochemical markers for arthritis, such as YKL-40 and urinary pyridinoline (Pyr). One hundred and thirty postmenopausal women with primary knee osteoarthritis (OA) aged 55-92 years wer...

journal_title：Clinical rheumatology

authors： Abe M,Takahashi M,Naitou K,Ohmura K,Nagano A

更新日期：2003-12-01 00:00:00

abstract：:We describe a patient with peripheral neuropathy, polymyalgia, arthralgia and cervical vertebral osteosclerosis who was subsequently diagnosed to have fatal multiple myeloma with IgG gammopathy and lambda urinary chains. The initial presentation and clinical features are discussed. ...

journal_title：Clinical rheumatology

authors： Samanta A,Hilton D,Roy S

更新日期：1990-06-01 00:00:00

abstract：:The relations between parameters obtained by clinical absorptiometric techniques, such as SPA, DPA, DXA and QCT, and geometrical and material parameters of bone structures are investigated. Two types of bone are considered: the diaphysis of a long bone, modelled as a hollow cylindrical structure consisting of compact ...

journal_title：Clinical rheumatology

authors： Van der Perre G,Lowet G

更新日期：1994-12-01 00:00:00

abstract：:Vascular involvement, especially in young males, is seen in up to 40% of the patients with Behcet's disease (BD) and is a major cause of mortality and morbidity. In this study, we investigated vessel wall thickness (VWT) and dilatation in lower extremity veins with Doppler ultrasound (US) in male BD patients. Sixty-on...

journal_title：Clinical rheumatology

authors： Alibaz-Oner F,Ergelen R,Mutis A,Erturk Z,Asadov R,Mumcu G,Ergun T,Direskeneli H

更新日期：2019-05-01 00:00:00

abstract：:Takayasu arteritis (TA) is a granulomatous vasculitis of large vessels with unknown aetiopathogenesis. An association between TA and tuberculosis (TB) has been suggested by several authors. The objective of this study was to perform a systematic review of the literature on the association of Mycobacterium tuberculosis...

journal_title：Clinical rheumatology

authors： Pedreira ALS,Santiago MB

更新日期：2020-04-01 00:00:00

abstract：:Immunoglobulins are often high in active rheumatoid arthritis and fall when treatment with a slow-acting anti-rheumatic drug is instituted. We assessed the value of monitoring immunoglobulins during penicillamine therapy; 145 patients were followed for up to 5 years, IgA, IgM and IgG levels were compared to 12 other c...

journal_title：Clinical rheumatology

authors： Williams A,Scott DL,Greenwood A,Huskisson EC

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:ABP 798 is a proposed biosimilar to the originator biologic rituximab, an anti-CD20 monoclonal antibody. This comparative clinical study evaluated the pharmacokinetics (PK), safety, and efficacy of ABP 798 versus rituximab reference product (RP) in patients with moderate-to-severe rheumatoid arthr...

journal_title：Clinical rheumatology

authors： Burmester G,Drescher E,Hrycaj P,Chien D,Pan Z,Cohen S

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare small to medium-size vessel systemic diseases. As their clinical picture, organ involvement, and factors influencing outcome may differ between countries and geographical areas, we decided to describe a large cohort of Polish AA...

journal_title：Clinical rheumatology

authors： Wójcik K,Wawrzycka-Adamczyk K,Włudarczyk A,Sznajd J,Zdrojewski Z,Masiak A,Czuszyńska Z,Majdan M,Jeleniewicz R,Klinger M,Jakuszko K,Rowaiye O,Brzosko M,Milchert M,Dębska-Ślizień A,Storoniak H,Tłustochowicz W,Kur-Zalewska

更新日期：2019-09-01 00:00:00

abstract：:The outbreak of SARS-CoV-2 has changed the habits and lives of people worldwide. Patients affected by systemic sclerosis (SSc) experienced constant fear because of their immunocompromised status. The aim of this study was to investigate the prevalence of SARS-CoV-2 infection and to analyze the lifestyle changes in a s...

journal_title：Clinical rheumatology

authors： Pellegrino G,Mohammad Reza Beigi D,Angelelli C,Stefanantoni K,Cadar M,Mancuso S,Conti F,Riccieri V

更新日期：2020-11-14 00:00:00

abstract：:An association has been demonstrated between haemorrhoids and joint hypermobility. Reasons for this are discussed. Many performing artists are hypermobile and the extra-articular features of joint hypermobility should not be forgotten or underestimated as a potential constraint upon performance. ...

journal_title：Clinical rheumatology

authors： Yousif UN,Bird HA

更新日期：2013-04-01 00:00:00

abstract：:Dego's disease is an uncommon thrombo-occlusive vasculopathy that presented with skin rash and thrombotic complications affecting internal organs that may simulate rheumatic diseases and may be brought to the attention of rheumatologists. We present here a case of a middle-aged woman who presented with acute bowel inf...

journal_title：Clinical rheumatology

authors： Chung HY,Trendell-Smith NJ,Yeung CK,Mok MY

更新日期：2009-07-01 00:00:00

abstract：:Although a number of reports have now described an association between polymorphism of the LMP2 gene and disease phenotype in HLA-B27 positive individuals with ankylosing spondylitis (AS), some describe associations with acute anterior uveitis, others with juvenile onset disease, and one report provides no association...

journal_title：Clinical rheumatology

authors： Maksymowych WP,Adlam N,Lind D,Russell AS

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:This study was designed to compare outcomes of dose reduction, withdrawal, and continuation of tofacitinib in patients with rheumatoid arthritis (RA) and to examine effectiveness of rescue with an original treatment regimen for disease flare. METHODS:We prospectively enrolled 100 patients who had high or mod...

journal_title：Clinical rheumatology

authors： Mori S,Ueki Y

更新日期：2019-12-01 00:00:00

abstract：:Despite improved quality of care for rheumatoid arthritis (RA) patients, many still experience treatment failure with a biologic agent and eventually switch to another biologic agent. We investigated patterns of biologic treatment and reasons for switching biologics in patients with RA. Patients with RA who had starte...

journal_title：Clinical rheumatology

authors： Park DJ,Choi SJ,Shin K,Kim HA,Park YB,Kang SW,Kwok SK,Kim SK,Nam EJ,Sung YK,Lee J,Lee CH,Jeon CH,Lee SS

更新日期：2017-05-01 00:00:00

abstract：:We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine sampl...

journal_title：Clinical rheumatology

authors： Otukesh H,Chalian M,Hoseini R,Chalian H,Hooman N,Bedayat A,Yazdi RS,Sabaghi S,Mahdavi S

更新日期：2007-12-01 00:00:00

abstract：:Kidney involvement in immuno-mediated diseases is a life threatening complication to be early detected. Glomerulo-tubular functional indices, kidney-released enzymes and metabolic profiles were assessed in 21 patients with systemic lupus erythematosus, progressive systemic sclerosis and mixed cryoglobulinaemia, withou...

journal_title：Clinical rheumatology

authors： Matteucci E,Migliorini P,Bertoni C,Dolcher MP,Marchini B,Giampietro O

更新日期：1996-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) reactivation is a common complication of immunosuppressive treatment in high prevalence countries. Biological disease-modifying antirheumatic drugs (bDMARDs) cause this adverse event more often than conventional immunosuppressants. The incidence of HBV reactivation during treatment for rheumati...

journal_title：Clinical rheumatology

authors： Schwaneck EC,Krone M,Kreissl-Kemmer S,Weißbrich B,Weiss J,Tony HP,Gadeholt O,Schmalzing M,Geier A

更新日期：2018-11-01 00:00:00

abstract：:In addition to the debilitating fatigue, the majority of patients with chronic fatigue syndrome (CFS) experience chronic widespread pain. These pain complaints show the greatest overlap between CFS and fibromyalgia (FM). Although the literature provides evidence for central sensitization as cause for the musculoskelet...

journal_title：Clinical rheumatology

authors： Meeus M,Nijs J

更新日期：2007-04-01 00:00:00

abstract：:The objective of this study was to describe ultrasonography (US) and magnetic resonance imaging (MRI) findings at painful Achilles tendons and entheses in patients with and without spondyloarthropathy (SpA and non-SpA) and healthy control persons (CTRLs). Particularly, we aimed to investigate if any changes differenti...

journal_title：Clinical rheumatology

authors： Wiell C,Szkudlarek M,Hasselquist M,Møller JM,Nørregaard J,Terslev L,Ostergaard M

更新日期：2013-03-01 00:00:00

abstract：:The purpose of this study is to evaluate the effects of targeting both the motivation and action phases of behaviour change in a 5-week intervention to increase physical activity (PA) among patients with rheumatoid arthritis (RA) not meeting current PA recommendations. In a randomised controlled trial, a control group...

journal_title：Clinical rheumatology

authors： Knittle K,De Gucht V,Hurkmans E,Peeters A,Ronday K,Maes S,Vlieland TV

更新日期：2015-02-01 00:00:00

abstract：:To demonstrate an as yet merely postulated generalized osteopathy in psoriatics, the serum calcium level, the alkaline phosphatase in the serum and the urinary excretion of hydroxyproline were evaluated in 24 patients with Ps and 24 patients with PA. Moreover, the bone bioptates from 25 patients with PA and 10 patient...

journal_title：Clinical rheumatology

authors： Hein G,Abendroth K,Müller A,Wessel G

更新日期：1991-03-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia ...

journal_title：Clinical rheumatology

authors： Caimmi C,Caramaschi P,Venturini A,Bertoldo E,Vantaggiato E,Viapiana O,Ferrari M,Lippi G,Frulloni L,Rossini M

更新日期：2018-04-01 00:00:00

abstract：:Ultrasound elastography (UE) is a new ultrasound-based imaging technique that provides information about elasticity and stiffness of tissues. This cross-sectional study aimed to identify the diagnostic importance of UE in supraspinatus impingement syndrome. Forty-one subjects, aged 38-70 years, were included in the st...

journal_title：Clinical rheumatology

authors： Demirel A,Baykara M,Koca TT,Berk E

更新日期：2018-06-01 00:00:00

abstract：:To explore whether femoral cartilage thickness is related (and changes) with muscle strength in subjects with knee osteoarthritis (OA). Forty patients (27 F, 13 M) with knee OA-who were under quadriceps muscle strengthening program-were enrolled in the study. Isokinetic/isometric knee muscle strength measurements (at ...

journal_title：Clinical rheumatology

authors： Tuna S,Balcı N,Özçakar L

更新日期：2016-08-01 00:00:00

abstract：:Gout is a disease with acute and/or chronic inflammation and tissue damage induced by the precipitation of monosodium urate crystal (MSU) crystals in bone joints, kidneys, and subcutaneous sites. In recent years, with the continuous research on gout animal models and patient clinical investigations, the mechanism of i...

journal_title：Clinical rheumatology

authors： Wu M,Tian Y,Wang Q,Guo C

更新日期：2020-10-01 00:00:00