Power Doppler ultrasonography of painful Achilles tendons and entheses in patients with and without spondyloarthropathy: a comparison with clinical examination and contrast-enhanced MRI.

Abstract:

:The objective of this study was to describe ultrasonography (US) and magnetic resonance imaging (MRI) findings at painful Achilles tendons and entheses in patients with and without spondyloarthropathy (SpA and non-SpA) and healthy control persons (CTRLs). Particularly, we aimed to investigate if any changes differentiate SpA from non-SpA. Finally, we investigated the reliability of US compared to clinical examination of Achilles tendinopathy, using MRI as gold standard reference. Twelve SpA patients and 15 non-SpA patients with pain and tenderness at at least one Achilles tendon and/or enthesis due to sports-related causes and 10 CTRLs were examined at the Achilles tendons and entheses with US, MRI and clinical assessment. Intratendinous changes, entheseal changes, bursitis and peritendonitis were assessed. An US interobserver substudy was performed in nine persons. US findings showed high agreement between observers (median 89 %, κ = 0.64) and with MRI (median 89 %, κ = 0.74). All inflammatory intratendinous changes were less frequent in SpA than non-SpA patients (p < 0.05). Entheseal changes and bursitis were found equally frequent in both patient groups except for enthesophytes, which were most common in the SpA group (p < 0.01). No findings were exclusively found in SpA. When MRI was considered gold standard, US showed higher sensitivity for intratendinous and entheseal changes than clinical examination (median sensitivity 0.83 versus 0.66). Especially, entheseal changes had higher sensitivity than clinical examination without loss of specificity. In conclusion, US performed by a trained operator can be a useful adjunct to clinical examination for improved assessment of Achilles tendons and entheses.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Wiell C,Szkudlarek M,Hasselquist M,Møller JM,Nørregaard J,Terslev L,Ostergaard M

doi

10.1007/s10067-012-2111-4

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

301-8

issue

3

eissn

0770-3198

issn

1434-9949

journal_volume

32

pub_type

杂志文章
  • IRAK2 is associated with systemic lupus erythematosus risk.

    abstract:INTRODUCTION:Interleukin-1 receptor-associated kinases (IRAKs) are serine-threonine kinases involved in toll-like receptor and interleukin-1 signaling pathways. They play a key role in inflammation and innate immunity. IRAKs have been previously incriminated in autoimmune diseases such as systemic lupus erythematosus (...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-019-04781-1

    authors: Boumiza A,Zemni R,Sghiri R,Idriss N,Hassine HB,Chabchoub E,Mzabi A,Ghannouchi N,Bouajina E,Ben Hadj Slama F

    更新日期:2020-02-01 00:00:00

  • Specificity and sensitivity of anti-beta2-glycoprotein I as compared with anticardiolipin antibody and lupus anticoagulant in Thai systemic lupus erythematosus patients with clinical features of antiphospholipid syndrome.

    abstract::Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-007-0566-5

    authors: Parkpian V,Verasertniyom O,Vanichapuntu M,Totemchokchyakarn K,Nantiruj K,Pisitkul P,Angchaisuksiri P,Archararit N,Rachakom B,Ayurachai K,Janwityanujit S

    更新日期:2007-10-01 00:00:00

  • A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverage.

    abstract::The pathogenesis of the idiopathic inflammatory myopathies has been postulated to be an environmental trigger causing the expression of the disease in a genetically predisposed patient. We report a case of anti-Jo1 antibody-positive myositis which was associated with pleural effusions, pericardial effusion with tampon...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-004-0890-y

    authors: Derk CT,Sandorfi N,Curtis MT

    更新日期:2004-08-01 00:00:00

  • Melorheostosis: report of a new case with linear scleroderma.

    abstract::Melorheostosis is a very rare bone disease of unknown etiology characterised by linear hyperostosis and associated with fibrosis of soft tissues and the skin. This uncommon sclerosing bone dysplasia was first described by Leri and Joanny in 1922, and since then, until 1993, approximately 300 cases were reported in the...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF01451298

    authors: Birtane M,Eryavuz M,Unalan H,Tüzün F

    更新日期:1998-01-01 00:00:00

  • Adult onset Still's disease diagnosed concomitantly with occult papillary thyroid cancer: paraneoplastic manifestation or coincidence?

    abstract::Adult onset Still's disease (AOSD) is an inflammatory disease of unknown etiology, characterized by spiking fever, evanescent salmon pink maculopapular rash, arthritis, and leukocytosis with neutrophilia. Malignant lymphoma is one of the most important differential diagnoses of AOSD. AOSD has been reported as one of p...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-009-1305-x

    authors: Ahn JK,Oh JM,Lee J,Kim SW,Cha HS,Koh EM

    更新日期:2010-02-01 00:00:00

  • Behçet's disease in Lebanon: clinical profile, severity and two-decade comparison.

    abstract::The aim of this study is to describe the clinical features of Lebanese patients with Behçet's disease (BD) followed up at a tertiary care center in Lebanon. A retrospective review of medical records of 90 patients who fulfilled the International Study Group (ISG) criteria for diagnosis was performed. The clinical char...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-005-0058-4

    authors: Hamdan A,Mansour W,Uthman I,Masri AF,Nasr F,Arayssi T

    更新日期:2006-05-01 00:00:00

  • Macrophage-colony stimulating factor (M-CSF) is increased in the synovial-like membrane of the periprosthetic tissues in the aseptic loosening of total hip replacement (THR).

    abstract::The aim of the study was to assess the eventual presence, cellular localization and extent of expression of the osteoclast activating cytokine M-CSF (CSF-1) in the periprosthetic tissues around loose total hip replacement (THR). Synovial-like membrane was obtained from the implant-to-bone interface and pseudocapsule f...

    journal_title:Clinical rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02238958

    authors: Xu JW,Konttinen YT,Waris V,Pätiälä H,Sorsa T,Santavirta S

    更新日期:1997-05-01 00:00:00

  • Imaging of sacroiliitis.

    abstract::Inflammation of one or both sacroiliac joints is a characteristic feature of patients with spondyloarthropathies (SpA). Sacroiliitis often leads to inflammatory back pain (IBP). IBP and asymmetric peripheral arthritis of the lower limbs are the main clinical symptoms and criteria for classification and diagnosis of Sp...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s100670050011

    authors: Braun J,Sieper J,Bollow M

    更新日期:2000-01-01 00:00:00

  • Raynaud's phenomenon: clinical spectrum of 118 patients.

    abstract:OBJECTIVES:To establish the prevalence of the associated secondary diseases in patients with Raynaud's phenomenon (RP) attending a rheumatology specialty centre and to determine the frequency with which a secondary illness develops in those having RP, in absence of a well-defined secondary cause. METHODS:118 consecuti...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-003-0726-1

    authors: De Angelis R,Del Medico P,Blasetti P,Cervini C

    更新日期:2003-10-01 00:00:00

  • Efficacy and safety profile of intravenous tocilizumab versus intravenous abatacept in treating female Saudi Arabian patients with active moderate-to-severe rheumatoid arthritis.

    abstract:OBJECTIVES:To compare the efficacy and safety of tocilizumab with those of abatacept in patients with active rheumatoid arthritis not responding to anti-tumor necrosis factor therapy. METHODS:A prospective, open-label study was carried out on adult females with moderate-to-severe rheumatoid arthritis. Patients were ra...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10067-019-04508-2

    authors: Elmedany SH,Mohamed AE,Galil SMA

    更新日期:2019-08-01 00:00:00

  • Unusual articular abnormalities in scleroderma.

    abstract::Articular involvement is described in a 58-year-old female patient with scleroderma. Radiological findings included intra-articular calcification, destructive osteoarthritis and selective involvement of the first metacarpal base. The discussion attempts to explain the way in which intra-articular calcification and ost...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02032338

    authors: Albert J,Ott H

    更新日期:1984-09-01 00:00:00

  • Serum levels of the bone turnover markers dickkopf-1, osteoprotegerin, and TNF-α in knee osteoarthritis patients.

    abstract::Knee osteoarthritis (KOA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Several inflammatory markers and cartilage degradation products can be used as biomarkers in OA. The key factors of bone metabolism in normal joint bone, dickkopf-1 (DKK1) and o...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-017-3690-x

    authors: Min S,Wang C,Lu W,Xu Z,Shi D,Chen D,Teng H,Jiang Q

    更新日期:2017-10-01 00:00:00

  • Silica-related rheumatoid arthritis without lung involvement.

    abstract::We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of s...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-002-0639-4

    authors: Markovits D,Schapira D,Wiener A,Nahir AM

    更新日期:2003-02-01 00:00:00

  • Biomarkers for diagnosis, monitoring of progression, and treatment responses in ankylosing spondylitis and axial spondyloarthritis.

    abstract::With the growing awareness of the impact of chronic back pain and axial spondyloarthritis and recent breakthroughs in genetics and the development of novel treatments which may impact best on early disease, the need for markers that can facilitate early diagnosis and profiling those individuals at the highest risk for...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-015-2949-3

    authors: Reveille JD

    更新日期:2015-06-01 00:00:00

  • Fear of movement and avoidance behaviour toward physical activity in chronic-fatigue syndrome and fibromyalgia: state of the art and implications for clinical practice.

    abstract::Severe exacerbation of symptoms following physical activity is characteristic for chronic-fatigue syndrome (CFS) and fibromyalgia (FM). These exacerbations make it understandable for people with CFS and FM to develop fear of performing body movement or physical activity and consequently avoidance behaviour toward phys...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-013-2277-4

    authors: Nijs J,Roussel N,Van Oosterwijck J,De Kooning M,Ickmans K,Struyf F,Meeus M,Lundberg M

    更新日期:2013-08-01 00:00:00

  • Modifiable cardiovascular risk factors in patients with ankylosing spondylitis.

    abstract::The aim of this study was to evaluate whether modifiable cardiovascular disease (CVD) risk factors, e.g. atherogenic blood lipids, hypertension and lifestyle-related factors such as smoking, diet and physical inactivity, differ among patients with ankylosing spondylitis (AS) in comparison to the general population. Ei...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-013-2410-4

    authors: Sundström B,Johansson G,Johansson I,Wållberg-Jonsson S

    更新日期:2014-01-01 00:00:00

  • Serum adipokine levels in patients with sarcoidosis.

    abstract:BACKGROUND:Sarcoidosis is a chronic inflammatory disease characterized by non-caseating granuloma which etiology is unknown yet. Adipokines are different proteins synthesized by adipose tissue that have an influence on angiogenesis, hemostasis, lipid metabolism, and immune system regulation. Adipokines may play a role ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-020-04980-1

    authors: Kobak S,Semiz H,Akyildiz M,Gokduman A,Atabay T,Vural H

    更新日期:2020-07-01 00:00:00

  • Combined diabetes and arthritis are associated with declined gait speed.

    abstract::This study investigated the association of combined arthritis and diabetes, diabetes only, and arthritis only compared with neither with gait speed in the general population. This cross-sectional study included data from the second wave of Midlife in the United States-2 (MIDUS 2) project 4: Biomarker Project, 2004-200...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-020-05370-3

    authors: Alenazi AM,Alshehri MM,Alqahtani BA,Alanazi AD,Bindawas SM

    更新日期:2020-08-27 00:00:00

  • Early diagnosis of psoriatic arthritis among psoriasis patients: clinical experience sharing.

    abstract:BACKGROUND:The early detection of psoriatic arthritis (PSA) poses a challenge to rheumatologists, even when their diagnosis is aided by sonography. In order to facilitate early detection of PSA among patients with psoriasis (PSO), we retrospectively analyzed of the relationships between serological markers and comorbid...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-020-05132-1

    authors: Su YJ

    更新日期:2020-12-01 00:00:00

  • High resolution computed tomography for the evaluation of lung involvement in 101 patients with scleroderma.

    abstract::The aim of the study was to investigate the pulmonary parenchymal abnormalities by high resolution computed tomography (HRCT) in patients with various forms of scleroderma. Three scans were performed sequentially in all cases: one at the level of aortic arch, one at the tracheal carina and one 1-2 cm above the diaphra...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02207928

    authors: Dévényi K,Czirják L

    更新日期:1995-11-01 00:00:00

  • The role of outcome expectancies for a training program consisting of meditation, breathing exercises, and cold exposure on the response to endotoxin administration: a proof-of-principle study.

    abstract::Expectancies play a major role for the treatment outcome of a broad variety of immune-mediated conditions and may strengthen or mimic the effects of regular long-term therapies. This study adds to a recently published study of Kox et al. (PNAS 111:7379-7384, 2014) on the ability to voluntarily influence the physiologi...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10067-015-3009-8

    authors: van Middendorp H,Kox M,Pickkers P,Evers AW

    更新日期:2016-04-01 00:00:00

  • Idiopathic inflammatory myopathies-a review.

    abstract::The idiopathic inflammatory myopathies (IIM) constitute a subset of autoimmune conditions primarily affecting muscle, along with many extra-muscular manifestations. Proximal muscle weakness is the dominant symptom in the IIM. In addition, many patients will have cutaneous manifestations, pulmonary manifestations, and ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审

    doi:10.1007/s10067-015-2891-4

    authors: Jones J,Wortmann R

    更新日期:2015-05-01 00:00:00

  • Discriminating infectious meningitis versus neuropsychiatric involvement in patients with systemic lupus erythematosus: a single-center experience.

    abstract::The objective of this study is to identify the clinical differences between infectious meningitis and neuropsychiatric systemic lupus erythematosus (NPSLE) in patients with SLE. Clinical manifestations, laboratory test results, and prognoses of 14 SLE patients complicated with various infectious meningitis, hospitaliz...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-014-2726-8

    authors: Chen J,Feng X,Wang H,Hua B,Ding C,Liu B,Sun L

    更新日期:2015-02-01 00:00:00

  • Systemic mastocytosis, an unusual cause of osteoporosis.

    abstract::A 45-year-old patient is described presenting with severe axial osteoporosis. The presence of maculopapular skin lesions and the combination of osteolytic and osteoblastic bone lesions led to the tentative diagnosis of systemic mastocytosis. This diagnosis was confirmed by measurement of urinary histamine metabolites ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02206850

    authors: Schoenaers P,De Clerck LS,Timmermans U,Stevens WJ

    更新日期:1987-09-01 00:00:00

  • Functioning and health-related quality of life in Chinese patients with systemic sclerosis: a case-control study.

    abstract::The objective of the study was to study the functioning and health-related quality of life (HRQoL) in patients with systemic sclerosis (SSc) and its associated factors. Consecutive SSc patients and an equal number of age- and gender-matched healthy controls were recruited for the assessment of functioning and HRQoL by...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-014-2525-2

    authors: Chan PT,Mok CC,Chan KL,Ho LY

    更新日期:2014-05-01 00:00:00

  • Methotrexate-treated arthritis and lymphoproliferative disease--coincidence only?

    abstract::This paper describes four patients with inflammatory joint diseases treated with methotrexate who developed lymphoma either of unusual type or with bizarre clinical features. The pathogenesis of this unusual condition is discussed and the difficulty in differentiating it from the features of the initial disease is emp...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s100670170112

    authors: Braun-Moscovici Y,Schapira D,Balbir-Gurman A,Nahir AM

    更新日期:2001-01-01 00:00:00

  • Prolactinoma and systemic lupus erythematosus: do serum prolactin levels matter?

    abstract::The lactogenic hormone prolactin is produced in part by cells of the immune system and serves as an upregulator of immune function. Hyperprolactinemia is common in patients with systemic lupus erythematosus (SLE), raising the possibility that the hormone contributes to the excessive immune response in the disease. The...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-005-0117-x

    authors: Li M,Keiser HD,Peeva E

    更新日期:2006-07-01 00:00:00

  • Early diagnosis and treatment of ankylosing spondylitis in Africa and the Middle East.

    abstract::Ankylosing spondylitis (AS) is the prototype for spondyloarthritis primarily affecting young men. Geographic and ethnic variations exist in the prevalence and severity of AS and relate to the wide disparity in the frequency of human leukocyte antigen (HLA)-B27, a major genetic risk factor. The strength of the disease ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10067-012-2058-5

    authors: Rachid B,El Zorkany B,Youseif E,Tikly M

    更新日期:2012-11-01 00:00:00

  • Disease activity is associated with cognitive impairment in patients with rheumatoid arthritis.

    abstract:OBJECTIVE:To investigate the association between disease activity and cognitive impairment in patients with rheumatoid arthritis (RA). METHODS:A total of 464 patients from the rheumatoid arthritis registry of two academic centers, Siriraj and Phramongkutklao hospitals, were included. Demographic, clinical, and laborat...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10067-019-04488-3

    authors: Katchamart W,Narongroeknawin P,Phutthinart N,Srinonprasert V,Muangpaisan W,Chaiamnauy S

    更新日期:2019-07-01 00:00:00

  • Uric acid metabolism in two patients with coexistent Down's syndrome and gout.

    abstract::Two patients with coexistent Down's syndrome and gout are described. Although increased serum urate levels are frequently reported in Down's syndrome, only a few such patients have been described with concomitant gout. In our patients no significant alterations of the purine salvage pathway were found, and the turnove...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章

    doi:10.1007/BF02030760

    authors: Ciompi ML,Bazzichi LM,Bertolucci D,Mazzoni MR,Barbieri P,Mencacci S,Macchia D,Mariani G

    更新日期:1984-06-01 00:00:00