Biomarkers for diagnosis, monitoring of progression, and treatment responses in ankylosing spondylitis and axial spondyloarthritis.

abstract：:The current treatment for antiphospholipid syndrome (APS) with thrombotic manifestation is long-term anticoagulation. Vitamin K antagonists (VKA) are usually the agents of choice. However, VKA limitations, such as unpredictable anticoagulation effects due to interaction with diet and other drugs, require regular monit...

journal_title：Clinical rheumatology

authors： Signorelli F,Nogueira F,Domingues V,Mariz HA,Levy RA

更新日期：2016-03-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease causing joint damage and significant functional impairment. Methotrexate (MTX) remains the mainstay for the treatment of RA. MTX inhibits several enzymes of the folate and nucleotide pathways. Thymidylate synthase (TYMS) is an important enzyme in the d...

journal_title：Clinical rheumatology

authors： Muralidharan N,Misra DP,Jain VK,Negi VS

更新日期：2017-06-01 00:00:00

abstract：:Adult onset Still's disease (AOSD) is an inflammatory disease of unknown etiology, characterized by spiking fever, evanescent salmon pink maculopapular rash, arthritis, and leukocytosis with neutrophilia. Malignant lymphoma is one of the most important differential diagnoses of AOSD. AOSD has been reported as one of p...

journal_title：Clinical rheumatology

authors： Ahn JK,Oh JM,Lee J,Kim SW,Cha HS,Koh EM

更新日期：2010-02-01 00:00:00

abstract：:Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia (CREST) syndrome, a limited form of systemic sclerosis, is sometimes complicated by primary biliary cirrhosis (PBC). A 52- and 61-year-old Japanese woman with PBC-CREST overlap syndrome accompanied by Sjögren's syndrome, and Hashi...

journal_title：Clinical rheumatology

authors： Nakamura T,Higashi S,Tomoda K,Tsukano M,Sugi K

更新日期：2007-04-01 00:00:00

abstract：:Hepatitis B virus (HBV) reactivation is a common complication of immunosuppressive treatment in high prevalence countries. Biological disease-modifying antirheumatic drugs (bDMARDs) cause this adverse event more often than conventional immunosuppressants. The incidence of HBV reactivation during treatment for rheumati...

journal_title：Clinical rheumatology

authors： Schwaneck EC,Krone M,Kreissl-Kemmer S,Weißbrich B,Weiss J,Tony HP,Gadeholt O,Schmalzing M,Geier A

更新日期：2018-11-01 00:00:00

abstract：:Survival and outcomes have improved considerably among patients with juvenile dermatomyositis (JDM) in the west. However, mortality continues to be high in the developing world. There is paucity of literature on this aspect of JDM from developing countries. We reviewed case files of all patients with JDM registered in...

journal_title：Clinical rheumatology

authors： Singh S,Suri D,Aulakh R,Gupta A,Rawat A,Kumar RM

更新日期：2014-11-01 00:00:00

abstract：:Hyperuricemia is not only a risk factor for gout but also an independent determinant of hypertension, diabetes, and chronic kidney diseases. Although the incidence of gout in Korean adults is increasing, epidemiologic studies on hyperuricemia in the general Korean population are limited. Thus, this study aimed at eval...

journal_title：Clinical rheumatology

authors： Kim Y,Kang J,Kim GT

更新日期：2018-09-01 00:00:00

abstract：:Charcot joint or neuropathic arthropathy is described in certain neurological conditions. We report the case of a man who presented with a swollen ankle 10 days after a long walk, which rapidly progressed to a Charcot joint. A neurological examination revealed areflexia and insensitivity to temperature and pain. Elect...

journal_title：Clinical rheumatology

authors： Chappel R,Willems J,Martin JJ

更新日期：2000-01-01 00:00:00

abstract：:We encountered an adult patient with acute parvovirus B19 infection who presented with transient lupus-like symptoms (i.e., polyarthritis, fever, myalgia, pancytopenia, hypocomplementemia, and nephritis). Our case is characterized by the demonstration of acute nephritis as a complication of this infection, making it d...

journal_title：Clinical rheumatology

authors： Sugimoto T,Tsuda A,Uzu T,Kashiwagi A

更新日期：2008-01-01 00:00:00

abstract：:The aim of this study is to describe the clinical features of Lebanese patients with Behçet's disease (BD) followed up at a tertiary care center in Lebanon. A retrospective review of medical records of 90 patients who fulfilled the International Study Group (ISG) criteria for diagnosis was performed. The clinical char...

journal_title：Clinical rheumatology

authors： Hamdan A,Mansour W,Uthman I,Masri AF,Nasr F,Arayssi T

更新日期：2006-05-01 00:00:00

abstract：:Two cases of Paget's sarcoma of bone are described. The first one is mainly characterized by the almost simultaneous degeneration of the only two existing locations of the underlying Paget's disease. The second case is one of monostotic Paget's disease of the scapula disclosed by the malignant degeneration. ...

journal_title：Clinical rheumatology

authors： Huaux JP,Esselinckx W,Noel H,Grodos J,Nagant de Deuxchaisnes C

更新日期：1984-12-01 00:00:00

abstract：:Systemic sclerosis (SSc) is complicated by pulmonary hypertension and right ventricle (RV) failure in approximately 10% of the patients. Factors influencing the reactivity of pulmonary circulation to vasodilators are not established, while the examination of vasoreactivity is important in determining the treatment, be...

journal_title：Clinical rheumatology

authors： Plazak W,Gryga K,Sznajd J,Wilisowska J,Czarnobilska E,Goncerz G,Podolec P,Musial J

更新日期：2012-01-01 00:00:00

abstract：:The effects of vitamin C on 1,25(OH)2D3 synthesis in humans were evaluated; the study included 20 females. They were divided into 2 groups. The first of the 10 subjects (age range 55-71) received ascorbic acid at a dose of 150 mg/die i.v. for 10 days; the second 10 subjects (age range 55-69) received a placebo i.v. fo...

journal_title：Clinical rheumatology

authors： Cantatore FP,Loperfido MC,Magli DM,Mancini L,Carrozzo M

更新日期：1991-06-01 00:00:00

abstract：:To investigate the histological changes of synovium in cases of effect attenuation occurring after the use of infliximab in the treatment of rheumatoid arthritis (RA), we histologically assessed synovial tissue from ten methotrexate-treated RA patients and 12 infliximab-treated RA patients after arthroscopic synovecto...

journal_title：Clinical rheumatology

authors： Kanbe K,Inoue K,Inoue Y,Suzuki Y

更新日期：2008-06-01 00:00:00

abstract：:Expectancies play a major role for the treatment outcome of a broad variety of immune-mediated conditions and may strengthen or mimic the effects of regular long-term therapies. This study adds to a recently published study of Kox et al. (PNAS 111:7379-7384, 2014) on the ability to voluntarily influence the physiologi...

journal_title：Clinical rheumatology

authors： van Middendorp H,Kox M,Pickkers P,Evers AW

更新日期：2016-04-01 00:00:00

abstract：:Yao syndrome (YAOS), formerly named NOD2-associated autoinflammatory disease, is a periodic disease characterized by fever, dermatitis, polyarthritis, distal extremity swelling, and gastrointestinal and sicca-like symptoms associated with specific NOD2 sequence variants. All patients in the literature were Caucasians....

journal_title：Clinical rheumatology

authors： Yang X,Wu D,Li J,Shen M,Zhang W

更新日期：2018-12-01 00:00:00

abstract：:Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. Lymphadenopathy is rare in patients with WG. Here, we present the first case of WG whose initial manifestation was superficial lymphadenopathy (i.e. supraclavicular and axillary lymphadenop...

journal_title：Clinical rheumatology

authors： Hashizume T,Yamaguchi T,Matsushita K

更新日期：2002-11-01 00:00:00

abstract：:Recently, the Ankylosing Spondylitis Disease Activity Score (ASDAS), a new index, has been shown to be validated and highly discriminatory in assessing ankylosing spondylitis (AS) disease activity. This study is to evaluate the performance of ASDAS in a local Chinese cohort of AS in a cross-sectional setting and to co...

journal_title：Clinical rheumatology

authors： Au YL,Wong WS,Mok MY,Chung HY,Chan E,Lau CS

更新日期：2014-08-01 00:00:00

abstract：:This cross-sectional investigation examined the prevalence and severity of dysphonia, globus pharyngeus, and dysphagia in patients affected by immunomediated (IM) diseases. Seventy subjects were administered the Voice Handicap Index (VHI) (scale 0-4), Glasgow-Edinburgh Throat Scale (GETS) (scale from 0 to 7) for globu...

journal_title：Clinical rheumatology

authors： Galli J,Marchese MR,De Canio C,Di Salvo M,Olivieri I,Santandrea L,Paludetti G

更新日期：2019-01-01 00:00:00

abstract：:The patient, a 44-year old woman with systemic lupus erythematosus, (SLE), developed infarction of the bowel and spleen after occlusion of the inferior mesenteric and splenic arteries, necessitating colectomy and splenectomy. She had had previous cerebral thromboses and a lower limb deep vein thrombosis. Histological ...

journal_title：Clinical rheumatology

authors： Asherson RA,Morgan SH,Harris EN,Gharavi AE,Krausz T,Hughes GR

更新日期：1986-01-01 00:00:00

abstract：:It has been well established that, anti-thyroglobulin antibodies (ATG) and anti-microsomal antibodies (AMC) may be present in various thyroid disorders and other systemic autoimmune diseases, including Sjögren's syndrome (SS). However, presence of circulating autoantibodies to thyroid hormones, i.e. both to triiodothy...

journal_title：Clinical rheumatology

authors： Ozgen AG,Keser G,Erdem N,Aksu K,Gümüsdis G,Kabalak T,Doganavsargil E

更新日期：2001-01-01 00:00:00

abstract：:Psoriatic arthritis (PsA) is a chronic T cell-mediated inflammatory spondyloarthropathy affecting 10-40 % of psoriasis (PSO) patients (0.3-1.0 % of the general population). Recent epidemiological studies have shown an increased prevalence of cardiovascular (CV) risk factors and/or morbidity among PSO or PsA patients a...

journal_title：Clinical rheumatology

authors： Khraishi M,Aslanov R,Rampakakis E,Pollock C,Sampalis JS

更新日期：2014-01-01 00:00:00

abstract：:Severe thrombocytopenia with bleeding associated with a life-threatening thrombotic manifestation in the setting of antiphospholipid syndrome is a major diagnostic and therapeutic challenge for the clinician. Hemorrhage is a less common complication than thrombosis in patients with APS, although severe thrombocytopeni...

journal_title：Clinical rheumatology

authors： Nyo MT,Kalla AA

更新日期：2014-04-01 00:00:00

abstract：:Forty-four patients with typical palindromic rheumatism were typed for HLA-A,B,C and DR antigens. The mean duration of follow-up of our patients was 4.0 yrs. (range 1-12 yrs.). During this time 27% of patients showed a seropositivity; 22% of patients developed polyarthritis, 1 patient revealed a Sjögren syndrome and 3...

journal_title：Clinical rheumatology

authors： Barbieri P,Ciompi ML,Menicucci A,Pasero G

更新日期：1988-12-01 00:00:00

abstract：INTRODUCTION:Immunoglobulin A vasculitis (IgAV) is the most common form of childhood systemic vasculitis. It is mostly self-limiting and characterized by skin, joint, gastrointestinal tract, and kidney involvement. Microribonucleic acids (miRNAs) are 18-25 base-long non-coding RNA group acting on gene expression. They ...

journal_title：Clinical rheumatology

authors： Cebi AH,Demir F,Ikbal M,Kalyoncu M

更新日期：2020-10-10 00:00:00

abstract：:Osteonecrosis (ON) is a clinical entity characterized by death of bone marrow and trabecular bone as a result of disruption of blood supply to the bone. The antiphospholipid (APL) syndrome is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with APL antibodies. The involvement ...

journal_title：Clinical rheumatology

authors： Rostom S,Bahiri R,Hajjaj-Hassouni N

更新日期：2008-02-01 00:00:00

abstract：:Delayed diagnosis in patients with Churg-Strauss syndrome (CSS) is largely attributed to the variable and nonspecific presentation of the disease's initial symptoms. The aim of the study was to evaluate the effect of delayed diagnosis on the course of CSS. We conducted a retrospective study of 30 CSS patients followed...

journal_title：Clinical rheumatology

authors： Sokołowska B,Szczeklik W,Mastalerz L,Kuczia P,Wodkowski M,Stodółkiewicz E,Macioł K,Musiał J

更新日期：2013-03-01 00:00:00

abstract：:Inflammation of one or both sacroiliac joints is a characteristic feature of patients with spondyloarthropathies (SpA). Sacroiliitis often leads to inflammatory back pain (IBP). IBP and asymmetric peripheral arthritis of the lower limbs are the main clinical symptoms and criteria for classification and diagnosis of Sp...

journal_title：Clinical rheumatology

authors： Braun J,Sieper J,Bollow M

更新日期：2000-01-01 00:00:00

abstract：:In this study we aimed to investigate the findings in patients with adult-onset Still's disease (AOSD) admitted with fever of unknown origin (FUO) during the last 18 years in our unit, in order to discover the ratio of such patients to all patients with FUO during the same period, and to determine the clinical feature...

journal_title：Clinical rheumatology

authors： Mert A,Ozaras R,Tabak F,Bilir M,Ozturk R,Ozdogan H,Aktuglu Y

更新日期：2003-05-01 00:00:00

abstract：:The aim of this study is to compare the three classification criteria for rheumatoid arthritis (RA) in a large cohort of early arthritis patients. Patients who had at least one clinically swollen joint with disease duration no more than 1 year and age more than 18 years were enrolled. The clinical and laboratory param...

journal_title：Clinical rheumatology

authors： Ye H,Su Y,Li R,Zhao J,Liu X,Mei Y,Zhang Z,Guo J,Bi L,Liu X,Wang G,Liu J,Leng X,Gu F,Sun L,Zou Q,Fang Y,Jiang Q,Li Z

更新日期：2016-10-01 00:00:00