Abstract:
:Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. Lymphadenopathy is rare in patients with WG. Here, we present the first case of WG whose initial manifestation was superficial lymphadenopathy (i.e. supraclavicular and axillary lymphadenopathy). One year after the initial presentation, a mass appeared in the lung. Biopsy specimens obtained from supraclavicular lymph nodes and lung demonstrated granulomatous vasculitis. This patient was negative for classic antineutrophil cytoplasmic antibodies (c-ANCA). Treatment with glucocorticoids, cyclophosphamide and trimethoprim-sulfamethoxazole has induced complete remission.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Hashizume T,Yamaguchi T,Matsushita Kdoi
10.1007/s100670200128subject
Has Abstractpub_date
2002-11-01 00:00:00pages
525-7issue
6eissn
0770-3198issn
1434-9949journal_volume
21pub_type
杂志文章abstract::Antibodies to 65Kd heat-shock protein (hsp) of mycobacterium leprae were measured by enzyme-linked immunosorbent assay (ELISA) in the three immunoglobulin classes in paired sera and synovial fluids of patients with rheumatoid arthritis (RA). Titers of anti-hsp antibody were expressed by optical density (OD) values for...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02249023
更新日期:1994-06-01 00:00:00
abstract::Gastrointestinal tract (GIT) is the most common organ system involved in systemic sclerosis (SSc). GIT involvement is mainly attributed to GIT dismobility and wide mouth diverticular. GIT involvement in SSc can be also severely debilitating and even life threatening. To our knowledge, the presence of gastrointestinal ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0264-8
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate the interrelationship between the micro- and macrovasculature. METHODS:This is a cross-sectional study that examined SSc patients and fibromyalgia (FM) patients as controls. We assessed forearm peripheral vascular status and nailfold capillaroscopy. We evaluated the assoc...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05025-3
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:This study aims to analyze factors related to pregnancy outcomes in women with positive antiphospholipid antibodies and previous adverse pregnancy outcomes (APOs) prospectively. METHODS:Patients' characteristics were described. Factors associated with obstetric complications were analyzed using logistic regr...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05203-3
更新日期:2021-01-01 00:00:00
abstract::Tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1) and von Willebrand factor (vWF), all of endothelial origin and active in the haemostasis, were analysed in 74 patients with rheumatoid arthritis. The concentrations were related to extra-articular disease and to the incidence of thromboembol...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02231572
更新日期:1993-09-01 00:00:00
abstract::The aim of this research was to determine any correlations between Dickkopf-1 serum levels (Dkk-1, a natural inhibitor of the Wnt signaling pathway promoting osteoclastogenesis) and the Trabecular Bone Score (TBS), in systemic sclerosis (SSc) and rheumatoid arthritis (RA) patients. It also aimed at determining any dif...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4322-9
更新日期:2018-11-01 00:00:00
abstract::Reduced physical function and health-related quality of life are common in rheumatoid arthritis (RA), and further studies are needed that examine novel determinates of reduced physical function in RA. This study examines whether frailty, a state of increased vulnerability to stressors, is associated with differences i...
journal_title:Clinical rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10067-017-3541-9
更新日期:2017-05-01 00:00:00
abstract::The investigation concerned changes in vitamin A derivatives (retinol and retinyl) content in serum of patients suffering from two types of rheumatic diseases--rheumatoid arthritis (RA) and osteoarthrosis. Healthy women of similar age served as control. It was found that the retinol content of the serum in the group s...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02042773
更新日期:1982-09-01 00:00:00
abstract::Polyarteritis nodosa (PAN) is a necrotising vasculitis of medium-sized vessels of unknown origin. This type of vasculitis is usually systemic, but restriction to a single organ, for example the testis, the appendix or the gall bladder, can occur. Testicular pain or tenderness are frequent clinical features. In this re...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0970-5
更新日期:2008-11-01 00:00:00
abstract::We reported a case of dermatomyositis (DM) with liver disturbance in a 50-year-old Japanese female. She presented with fever, muscle weakness, and typical DM rashes. On clinical and serological examinations, the liver impairment was initially diagnosed as probable autoimmune hepatitis, which was denied by a histologic...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1397-3
更新日期:2010-08-01 00:00:00
abstract::To measure serum soluble transferrin receptor (s-TfR) levels in patients with rheumatoid arthritis (RA), sera were obtained from 50 Japanese RA patients and 20 healthy subjects. Both s-TfR and serum erythropoietin (EPO) levels were measured by enzyme-linked immunosorbent assay (ELISA). Routine laboratory tests were al...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/s100670170018
更新日期:2001-01-01 00:00:00
abstract::Evidence for Chagas disease reactivation (CDR) in rheumatologic patients under rheumatologic treatments (RTs) is scarce. To screen and follow-up patients with rheumatic diseases and concomitant Chagas disease under RT to detect CDR and to describe a possible relationship between CDR and specific RT. An observational, ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-021-05581-2
更新日期:2021-01-12 00:00:00
abstract::The ACR/EULAR Boolean remission criteria for rheumatoid arthritis (RA) include a strict cutoff for patient global assessment (PGA, value ≤ 1/10). Near-remission corresponds to remission for joint counts and C-reactive protein but with PGA > 1. The objective was to explore whether the contribution of PGA to remission a...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-3998-1
更新日期:2018-06-01 00:00:00
abstract::A 71-year-old male rheumatoid patient presented with MRSA septic arthritis. The impact of this organism on musculoskeletal practice is discussed. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF01450904
更新日期:1998-01-01 00:00:00
abstract::The effect of long-term (18-70 months) chloroquine treatment 250 mg daily, in rheumatoid arthritis (RA) was studied in 20 patients. Sedimentation rates were significantly reduced, as compared to a reference group of 10 RA patients on no treatment of disease modifying anti-rheumatic drugs. Radiographical progression of...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02041561
更新日期:1983-12-01 00:00:00
abstract::Electrocardiographic (ECG) and echocardiographic examinations and 24-h ECG Holter monitoring were carried out in 100 patients (age < 65 years) with rheumatoid arthritis (RA) of stages II-IV according to Steinbrocker's criteria. One hundred patients with osteoarthrosis, spondyloarthrosis and painful shoulder matched fo...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF01450894
更新日期:1998-01-01 00:00:00
abstract::Sudden death following steroid pulse therapy has been recently reported. Continuous electrocardiographic recording was performed 24 hours before, during, and 24 hours after each one to three high dose intravenous methyl prednisolone pulses administered of five patients with severe ankylosing spondylitis unresponsive t...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02715692
更新日期:1984-03-01 00:00:00
abstract::In the midst of the COVID-19 pandemic, further understanding of its complications points towards dysregulated immune response as a major component. Systemic lupus erythematosus (SLE) is also a disease of immune dysregulation leading to multisystem compromise. We present a case of new-onset SLE concomitantly with COVID...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-020-05310-1
更新日期:2020-09-01 00:00:00
abstract::Macrophage activation syndrome (MAS), which can also be considered as reactive hemophagocytic syndrome (HPS), is a rare and potentially fatal complication of rheumatic diseases. We describe a 42-year-old woman in whom MAS developed as a complication of ankylosing spondylitis (AS). She suffered from fever and low back ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0538-9
更新日期:2007-11-01 00:00:00
abstract::Eighty patients with Reiter's syndrome (RS) were studied retrospectively. A comparison was made between patients with the complete syndrome and patients with the incomplete syndrome. A comparison was also made between patients with and without HLA-B27. There were no major differences in severity and duration of the ar...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02030971
更新日期:1986-01-01 00:00:00
abstract::The aim of the study was to describe the long-term toxicity of antirheumatic and anti-inflammatory drugs in a paediatric rheumatology clinic population. One hundred and seventeen children were studied on first admission to a paediatric rheumatology clinic and after a mean of 8.6 +/- 0.4 years of follow-up. Medical rec...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF01451288
更新日期:1998-01-01 00:00:00
abstract::One hundred and eighteen elbows in 59 patients who started treatment using disease-modifying antirheumatic drugs (DMARDs) in the first year of the disease were followed-up for more than 10 years without biologic agents. Using annual radiographs of the elbow joint, Larsen grade (LG) was determined, and bone absorption ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0814-8
更新日期:2008-07-01 00:00:00
abstract::Inflammation of one or both sacroiliac joints is a characteristic feature of patients with spondyloarthropathies (SpA). Sacroiliitis often leads to inflammatory back pain (IBP). IBP and asymmetric peripheral arthritis of the lower limbs are the main clinical symptoms and criteria for classification and diagnosis of Sp...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s100670050011
更新日期:2000-01-01 00:00:00
abstract::Takayasu's arteritis (TA) is a rare vasculitis that affects the aorta and its primary branches. Heterogeneous clinical manifestations have been described in different geographical areas. We aimed to evaluate demographic, clinical, and angiographic features and the outcome in 16 TA patients who were followed in a singl...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-1009-7
更新日期:2009-02-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a multi-system chronic inflammatory disease with a broad spectrum of clinical and serological manifestations. Although clinical evidence of proximal skeletal muscle involvement is not rare in patients with SLE, there is no knowledge about the effects of SLE on the macroscopic stru...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2249-8
更新日期:2013-08-01 00:00:00
abstract::Behcet's disease (BD) is a systemic vasculitis characterized by genital and oral ulcers, uveitis, and other organs' involvement. Left ventricular (LV) diastolic dysfunction has been documented in BD. However, conventional echocardiographic techniques have serious limitations like its dependence on preload, afterload a...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0208-3
更新日期:2006-11-01 00:00:00
abstract::Rheumatoid arthritis (RA) is associated with increased vascular calcification, although the rate of progress of calcification is uncertain. The aim of the study was to evaluate the progression of and the predictors for calcification in different vascular beds over 10 years. The 10-year actual coronary calcium score (C...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3536-y
更新日期:2017-04-01 00:00:00
abstract::In juvenile chronic arthritis (JCA) the indices of disease activity, such as joint swelling, pain, tenderness, and limitation of motion, may poorly correlate with the degree of functional impairment. Since the improvement of functional capacity is one of the main objectives of treatment, we evaluated the effect of met...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208347
更新日期:1995-05-01 00:00:00
abstract::The cellular localization of the Ro/SS-A antigen was defined using indirect immunofluorescence and eight monospecific anti- Ro/SS-A antisera which were identified by immunoblotting. Several mammalian tissues were used as substrates. The Ro/SS-A antigen was located mainly in the nucleus of dog liver and Hep-2-cells, an...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02030965
更新日期:1986-01-01 00:00:00
abstract::One hundred and twenty patients with hemisacralization of the L5 vertebra associated with LBP underwent clinical, conventional X-ray and CT examinations. More than 50% of the patients had scoliosis. One third of the patients had disc lesions. Sacroiliac joint sclerosis was noted in two thirds of the cases. Almost all ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02054251
更新日期:1986-09-01 00:00:00