Uric acid metabolism in two patients with coexistent Down's syndrome and gout.

Abstract:

:Two patients with coexistent Down's syndrome and gout are described. Although increased serum urate levels are frequently reported in Down's syndrome, only a few such patients have been described with concomitant gout. In our patients no significant alterations of the purine salvage pathway were found, and the turnover parameters of uric acid, determined by means of a 14C-labeled uric acid study, were consistent with the metabolic findings observed in normoexcretor gouty patients.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Ciompi ML,Bazzichi LM,Bertolucci D,Mazzoni MR,Barbieri P,Mencacci S,Macchia D,Mariani G

doi

10.1007/BF02030760

subject

Has Abstract

pub_date

1984-06-01 00:00:00

pages

229-33

issue

2

eissn

0770-3198

issn

1434-9949

journal_volume

3

pub_type

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