Abstract：
:The objective of this study is to identify the clinical differences between infectious meningitis and neuropsychiatric systemic lupus erythematosus (NPSLE) in patients with SLE. Clinical manifestations, laboratory test results, and prognoses of 14 SLE patients complicated with various infectious meningitis, hospitalized in the Affiliated Drum Tower Hospital of Nanjing University Medical School in the past 7 years, were reviewed and compared with those of 34 concomitantly treated NPSLE patients. Our study shows that mortality rate was much higher in SLE patients with infectious meningitis than in NPSLE patients. Compared to NPSLE, those with infectious meningitis had lower SLE Disease Activity Index (SLEDAI), but higher doses of corticosteroids 1 month before the occurrence of CNS symptoms. Headache, high fever, and vomiting were more common in patients with infectious meningitis, accompanied with the elevation of C-reactive protein level. Cerebrospinal fluid (CSF) examination showed increased levels of leukocytes and proteins but decreased glucose level in patients with infectious meningitis. We conclude that for SLE patients exhibiting CNS symptoms, high fever, high intake of corticosteroids, and abnormal CSF are important clues for the coexistence of infectious meningitis, especially tuberculous meningitis.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Chen J,Feng X,Wang H,Hua B,Ding C,Liu B,Sun Ldoi
10.1007/s10067-014-2726-8subject
Has Abstractpub_date
2015-02-01 00:00:00pages
365-9issue
2eissn
0770-3198issn
1434-9949journal_volume
34pub_type
杂志文章abstract：OBJECTIVE:This study aimed to identify the clinical characteristics of systemic lupus erythematosus-primary biliary cholangitis (SLE-PBC) patients and to compare the manifestations and prognosis with systemic lupus erythematosus (SLE) patients. METHODS:Twenty-one inpatients with concomitant SLE and primary biliary cho...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05457-x
更新日期：2020-10-16 00:00:00
abstract：:The aim of this study was to determine the serum interleukin-18 (IL-18) levels in patients with systemic lupus erythematosus (SLE) and to assess their relationship with disease activity. Thirty-five patients with SLE and 35 age- and sex-matched controls were enrolled in this study. Paired serum samples were collected ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-004-0867-x
更新日期：2004-06-01 00:00:00
abstract：:The aim of this study was to identify and evaluate laboratory parameters associated with normal bone mineral density (BMD) and to test if -308 tumour necrosis factor (TNF) alpha gene promoter polymorphisms could influence BMD. We performed a comparative cross-sectional study of four main groups: young healthy individu...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0706-y
更新日期：2008-03-01 00:00:00
abstract：:To determine serum interleukin-33 (IL-33) levels and their associations with clinical parameters in patients with systemic sclerosis (SSc). Serum IL-33 levels were examined by enzyme-linked immunosorbent assay in 69 patients with SSc and 30 healthy individuals. In a retrospective longitudinal study, sera from 14 patie...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1686-5
更新日期：2011-06-01 00:00:00
abstract：:A case of left brachial plexus compression by an iatrogenic arteriovenous fistula was treated by detachable balloon technique with immediate relief of pain. Good results on paresia were obtained in a few weeks. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02330599
更新日期：1987-12-01 00:00:00
abstract：:The authors wish to acknowledge that whilst this study and that published in Hammad et al [1] explore different areas - blood cell ratios and serum endocan, respectively - the reader may identify some similarities between the papers owing to the same patient cohort being analysed in both studies. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10067-019-04583-5
更新日期：2019-07-01 00:00:00
abstract：UNLABELLED:It has been suggested that in some patients non-traumatic aseptic osteonecrosis of the hip (AOH) could be the result of the intra-osseous thrombosis. Antiphospholipid antibodies (APL) have been associated with venous and arterial occlusive events and the association between AOH and APL syndrome has been repo...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02242453
更新日期：1997-06-01 00:00:00
abstract：:A 71-year-old male rheumatoid patient presented with MRSA septic arthritis. The impact of this organism on musculoskeletal practice is discussed. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF01450904
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:To assess whether systemic sclerosis (SSc) is associated with total knee arthroplasty (TKA) outcomes. METHODS:We used the 1998-2014 US National Inpatient Sample. We conducted multivariable-adjusted logistic regression analyses to examine the association of a diagnosis of SSc with post-TKA in-hospital complic...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04754-4
更新日期：2020-01-01 00:00:00
abstract：:The effects of 10 ml of evening primrose oil or olive oil, administered twice daily for 12 weeks, on clinical and laboratory signs and on plasma prostaglandins were studied in 18 patients with rheumatoid arthritis. The plasma concentration of PGE2 decreased and that of TxB2 increased in both treatment groups, but no s...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02030080
更新日期：1989-06-01 00:00:00
abstract：:The aim of this study was to comparatively evaluate oxidative status of ankylosing spondylitis (AS) patients receiving anti-tumor necrosis factor (TNF) or non-steroid anti-inflammatory drugs (NSAID). Forty-seven patients with AS and 27 healthy controls were enrolled. Of these, 23 were on anti-TNF (group 1) and 24 on N...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1325-6
更新日期：2010-03-01 00:00:00
abstract：:This study was designed to explore the profile of immune cell subsets, including T, B, natural killer (NK), and NKT cells, in systemic lupus erythematosus (SLE) patients, and to determine their relationships with the clinical index and the effects of cyclophosphamide (CYC) and mycophenolate mofetil (MMF) treatment. SL...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-1958-8
更新日期：2012-06-01 00:00:00
abstract：:A correlation study was performed on the degree of muscle weakness in 36 patients with dermatomyositis and 69 with polymyositis in relation to muscle biopsy findings, electromyography (EMG) abnormalities, and serum concentrations of creatine kinase (CK), aspartate aminotransferase (AST) and alanine aminotransferase (A...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02030515
更新日期：1990-12-01 00:00:00
abstract：:Increased IFN-γ levels have been associated with systemic lupus erythematosus (SLE). However, the relationships among IFN-γ, type I interferons (IFNs) and clinical features have not been extensively studied. Peripheral blood samples from 44 SLE patients and 36 healthy donors (HDs) were collected. Quantitative real-tim...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4138-7
更新日期：2018-10-01 00:00:00
abstract：:The aim of this study was to describe the abnormalities identified with conventional MRI in children with neuropsychiatric systemic lupus erythematosus (NPSLE). This was single-centre (Great Ormond Street Hospital, London) retrospective case series of patients with juvenile NPSLE seen in 2003-2013. Brain MR images of ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-016-3376-9
更新日期：2016-10-01 00:00:00
abstract：UNLABELLED:There is a paucity of data on the impact of chronic rheumatic diseases on functional disability and overall health-related quality of life (HRQOL) in Africans. MATERIALS AND METHODS:We compared Black South Africans (BSA) with rheumatoid arthritis (RA) (n=50) and systemic lupus erythematosus (SLE) (n=50) to ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0215-4
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVES:This study evaluated Superb Microvascular Imaging (SMI) technology for detection of active synovitis in patients with rheumatoid arthritis (RA). METHODS:Between June 2015 and October 2016, 56 patients with RA (42 females; mean age, 53.2 years) underwent gray-scale ultrasound (US) imaging, power Doppler imag...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04550-0
更新日期：2019-09-01 00:00:00
abstract：:The aim of this study was to assess the role of oxidative stress in the pathogenesis of Henoch-Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase (ARYL), and paraoxonase (PON) as antioxidant enzymes and serum malondialdehyde (MDA) level as an indicator of lipid peroxidation, together wi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0671-5
更新日期：2008-02-01 00:00:00
abstract：:This study aimed to compare the intraobserver and interobserver reliability of three-dimensional (3D) and two-dimensional (2D) power Doppler ultrasonography (PDUS) and to assess the relationship between 3D PDUS and clinical parameters in patients with rheumatoid arthritis (RA). Bilateral second/third metacarpophalange...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1811-5
更新日期：2012-02-01 00:00:00
abstract：:It has recently been claimed that some of the symptoms in patients with Behçet's disease (BD) can be activated after the patient has stopped smoking. In this study we investigated the effect of smoking on the symptoms of Behçet's disease. Fifty asymptomatic current smokers (CS) who promised to stop smoking (group 1) a...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670070020
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:To assess the efficacy and safety of the commonly used urate-lowering therapies (ULTs): febuxostat, allopurinol, and lesinurad in hyperuricemic patients with gout. METHODS:We included all randomized controlled trials (RCTs) that compared ULTs with placebo or head to head. The primary efficacy endpoint was t...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05272-4
更新日期：2021-02-01 00:00:00
abstract：:The objective of this study was to analyze the clinical, laboratorial, and therapeutical response of polymyalgia rheumatica (PMR) to anti-tumor necrosis factor (anti-TNF) treatment. We systematically searched English articles on the subjects of PMR who were treated with TNF blockers in Pubmed from 1994 to 2010. In add...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-011-1914-z
更新日期：2012-03-01 00:00:00
abstract：:Susceptibility to ankylosing spondylitis is highly genetic, with a heritability greater than 90 %. Presence of the HLA-B27 MHC class I allele remains the greatest genetic risk factor identified to date. Beyond its nominal role in antigen presentation, HLA-B27 displays interesting and possibly unique biochemical charac...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-3117-5
更新日期：2016-06-01 00:00:00
abstract：:Objectives of this study were to examine work disability (WD) and its leading causes in incident SLE patients. Data were derived from the Finnish nationwide registries to identify all non-retired, 18 to 64-year-old incident SLE patients between 2000 and 2007. Sick benefits and WD pensions and the causes for them were ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4066-6
更新日期：2018-05-01 00:00:00
abstract：:Although mesenteric vasculitis due to Henoch-Schönlein purpura (HSP) is relatively uncommon, it is the most life-threatening manifestation associated with high mortality. We describe a 15-year-old boy with HSP who had massive gastrointestinal bleeding and ileus but delayed onset of the purpuric rash. Abdominal ultraso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-002-0676-z
更新日期：2003-05-01 00:00:00
abstract：:The aims of the study were to assess the health-related quality of life (QOL) in patients with Takayasu's arteritis (TA) by two different generic QOL instruments and to compare the results with those patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), and healthy controls (HC). A cross-sectional stud...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0813-9
更新日期：2008-07-01 00:00:00
abstract：:We report a case of a 56-year-old woman with an alleged diagnosis of an acute coronary syndrome that was later correctly identified in our Cardiology Unit as antisynthetase syndrome (AS) with inflammatory cardiac involvement. In this case report, we focus on clinical features of this rare autoimmune disease aiming to ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-019-04527-z
更新日期：2019-08-01 00:00:00
abstract：:With the aim of evaluating the role of 1,25 dihydroxyvitamin D in the pathogenesis of osteoporosis, this hormone was studied in 90 subjects. They were divided into three groups: the first group consisted of 30 normal female subjects (aged 30 to 45); the second group comprised 30 elderly female subjects (aged 67 to 90)...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02031970
更新日期：1990-06-01 00:00:00
abstract：:Polyarteritis nodosa (PAN) is a necrotising vasculitis of medium-sized vessels of unknown origin. This type of vasculitis is usually systemic, but restriction to a single organ, for example the testis, the appendix or the gall bladder, can occur. Testicular pain or tenderness are frequent clinical features. In this re...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-008-0970-5
更新日期：2008-11-01 00:00:00
abstract：:Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0566-5
更新日期：2007-10-01 00:00:00
