Abstract:
:Objectives of this study were to examine work disability (WD) and its leading causes in incident SLE patients. Data were derived from the Finnish nationwide registries to identify all non-retired, 18 to 64-year-old incident SLE patients between 2000 and 2007. Sick benefits and WD pensions and the causes for them were monitored until the end of 2008. A total of 446 working-aged, incident SLE patients available for work force (mean age 42 ± 13 years, 89% females) were found. During the follow-up (median 5.3 years), WD pension was granted to 27 patients. The most common cause was SLE itself (14 patients, 52%), with cumulative incidence of 3.4% (95% CI 1.9 to 5.8) in 5 years and 5.0% (95% CI 3.0 to 8.5) in 8 years, followed by musculoskeletal and psychiatric causes. The age- and sex- adjusted incidence ratio for WD pension in SLE patients due to any cause was 5.4 (95% CI 3.7 to 7.9) compared to the Finnish population. The mean number of WD days was 32 (95% CI 28 to 35) per patient-year among all SLE patients during the follow-up. The study concludes that SLE patients have an increased risk for WD already in early course of the disease.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Elfving P,Puolakka K,Rantalaiho V,Kautiainen H,Virta LJ,Kaipiainen-Seppänen Odoi
10.1007/s10067-018-4066-6subject
Has Abstractpub_date
2018-05-01 00:00:00pages
1413-1416issue
5eissn
0770-3198issn
1434-9949pii
10.1007/s10067-018-4066-6journal_volume
37pub_type
杂志文章abstract::Joint hypermobility syndrome (JHS) is common in patients presenting to rheumatologists and can cause a range of symptoms leading to physical and psychological distress. Chronic musculoskeletal pain in patients with JHS often responds poorly to analgesics, and a pain management approach may be helpful. Since patients w...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2539-9
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To explore the 18F-fluoro-dexoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging characteristics of adult-onset Still's disease (AOSD) and its significance in differential diagnosis from other connective tissue diseases (CTDs). METHODS:FDG PET/CT images of 54 patients with AOSD...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05041-3
更新日期:2020-09-01 00:00:00
abstract::Autoinflammatory disorders (AIDs) are a novel class of diseases elicited by mutations in genes regulating the homeostasis of innate immune complexes, named inflammasomes, which lead to uncontrolled oversecretion of the proinflammatory cytokine interleukin-1β. Protean inflammatory symptoms are variably associated with ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-014-2721-0
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To investigate the association between disease activity and cognitive impairment in patients with rheumatoid arthritis (RA). METHODS:A total of 464 patients from the rheumatoid arthritis registry of two academic centers, Siriraj and Phramongkutklao hospitals, were included. Demographic, clinical, and laborat...
journal_title:Clinical rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10067-019-04488-3
更新日期:2019-07-01 00:00:00
abstract::Immunoglobulins are often high in active rheumatoid arthritis and fall when treatment with a slow-acting anti-rheumatic drug is instituted. We assessed the value of monitoring immunoglobulins during penicillamine therapy; 145 patients were followed for up to 5 years, IgA, IgM and IgG levels were compared to 12 other c...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02239191
更新日期:1988-09-01 00:00:00
abstract::This study demonstrates whether serum β2-microglobulin (β2-MG) level can be an indicator of the status of systemic lupus erythematosus (SLE) and adult-onset Still's disease (AOSD), and development of hemophagocytic syndrome (HPS) complication. Serum β2-MG level was compared between the active and inactive statuses of ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2220-8
更新日期:2013-07-01 00:00:00
abstract::Efficacy of hip protector pads to prevent hip fracture is controversial. This study was done to evaluate two comparable groups for fracture risk. Two matched cohorts of long-term care residents in Canada, assessing the efficacy of hip protector pads. Evaluation included demographics, medications/diagnoses, cognition (...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1115-1
更新日期:2009-06-01 00:00:00
abstract::The aim of this study is to compare the three classification criteria for rheumatoid arthritis (RA) in a large cohort of early arthritis patients. Patients who had at least one clinically swollen joint with disease duration no more than 1 year and age more than 18 years were enrolled. The clinical and laboratory param...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-016-3281-2
更新日期:2016-10-01 00:00:00
abstract::A 62-year-old man who suffered from severe deforming arthritis, secondary to chronic tophaceous gout with multilobular, solid, tender, enlarged subcutaneous nodules, and draining tophi in right second finger, was treated by free flap and finally got the more functional and aesthetic result. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1321-x
更新日期:2010-03-01 00:00:00
abstract::Socio-economic gradients in occurrence of diseases have been reported for many chronic conditions. However, whether the magnitude of socio-economic gradients differs across diseases and the extent to which lifestyle mediates such relationships are not known. Cross-sectional data from The National Monitor on Musculoske...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4158-3
更新日期:2018-12-01 00:00:00
abstract::Our objective was to assess the progression of osteoarthritis (OA) using scoring systems based on the anatomical changes recorded in the finger joints on standard radiographs and to test how far these scoring systems could be used to evaluate the effects of candidate "disease modifying osteoarthritis drugs" (DMOAD). T...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s10067-002-8290-7
更新日期:2002-06-01 00:00:00
abstract::Atherosclerosis plays a key role in cardiovascular disease in patients with rheumatoid arthritis (RA). Although therapy with TNF-alpha antagonists has resulted in dramatic improvement in the prognosis of RA, its effects on circulatory lipids are unclear. We conducted a systematic review of the literature to summarize ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-010-1405-7
更新日期:2010-09-01 00:00:00
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journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-002-0639-4
更新日期:2003-02-01 00:00:00
abstract::The aim of this study was to evaluate whether corticosteroid use is the etiological agent in acute pancreatitis in patients with systemic lupus erythematosus, or whether it is related to the underlying connective tissue disorder. Hospital admissions at Thomas Jefferson University Hospital between 1982 and 2002 that ca...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-003-0793-3
更新日期:2004-04-01 00:00:00
abstract::The purpose of the study was to assess the 1-year outcome of definitive reactive arthritis (ReA) after a waterborne outbreak. A cohort of 21 patients (15 females and 6 males, median age 54 years) with ReA related to an extensive waterborne outbreak in Finland was clinically followed-up by rheumatologists with visits a...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2247-x
更新日期:2013-08-01 00:00:00
abstract::Heart rate variability (HRV) gives information about sympathetic parasympathetic autonomic balance. Our purpose was to determine whether HRV is abnormal in patients with Sjögren's syndrome. In 16 patients with Sjögren's syndrome and 30 matched controls, a short time analysis of HRV was performed for both the frequency...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/pl00011180
更新日期:2000-01-01 00:00:00
abstract:INTRODUCTION:We investigated whether rheumatoid arthritis (RA)-related autoantibodies were associated with abnormalities on pulmonary function tests (PFTs). METHODS:We studied RA serostatus and PFT abnormalities within a RA registry. RA serostatus was assessed by research assays for cyclic citrullinated peptide (CCP) ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04733-9
更新日期:2019-12-01 00:00:00
abstract::We reviewed the records of 315 patients with rheumatoid arthritis (RA) treated with low-dose methotrexate (MTX) and evaluated the conditions contributing to thrombocytopenia. Thirteen out of 315 patients with RA presented with low platelet counts (< or = 100.000/mm3). The age of these patients (51 +/- 12.6 years) did ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02230334
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION/OBJECTIVES:Cardiovascular risk management of patients with systemic lupus erythematosus (SLE) is medically relevant. The objectives were to estimate the cardiovascular risk by different strategies in patients with SLE, analyzing which proportion of patients would be candidates to receive statin therapy, an...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04856-z
更新日期:2020-02-01 00:00:00
abstract::The objective of this study is to identify the clinical differences between infectious meningitis and neuropsychiatric systemic lupus erythematosus (NPSLE) in patients with SLE. Clinical manifestations, laboratory test results, and prognoses of 14 SLE patients complicated with various infectious meningitis, hospitaliz...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2726-8
更新日期:2015-02-01 00:00:00
abstract:INTRODUCTION:Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory benign breast disease. Although the etiology of this disease is unknown, it has been suggested that hormonal disorders, autoimmunity, smoking, and α1-antitrypsin deficiency may play a role in the etiopathogenesis. The aim is to investi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-04925-8
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The purpose of this study was to develop an understanding of treatment preferences in patients with inflammatory arthritis (IA) [rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA)] focussing on treatment attributes that patients' value, their relative importan...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-019-04843-4
更新日期:2020-04-01 00:00:00
abstract::The aim of this study was to evaluate the long-term efficacy and safety of single or 1-3 weekly injections of hylan G-F 20 at 1 year following the first injection for knee osteoarthritis (OA). Searches were conducted in PubMed/MEDLINE, Embase, and CENTRAL and included relevant conference proceedings (January 1, 1995-A...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-020-05477-7
更新日期:2020-10-27 00:00:00
abstract::Idiopathic Inflammatory myopathies (IIM) are rare disorders. The aim of our study was to determine the incidence of IIM in a well-defined Slovenian region. This retrospective study was conducted at the Department of Rheumatology, University Medical Centre Ljubljana, the only secondary/tertiary rheumatology center in a...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4237-5
更新日期:2019-02-01 00:00:00
abstract::Biologic therapies have brought improved efficacy in the field of rheumatoid arthritis (RA), but their use in clinical practice may be limited by concerns over cost. Predictive models are, therefore, needed to identify those people with RA with the worst potential outcomes, who will benefit most from the use of these ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-010-1639-4
更新日期:2011-03-01 00:00:00
abstract::This article is a small case series that aims to discuss the impact of depression, vascular, and fibrotic changes on development of erectile dysfunction (ED) in patients with systemic sclerosis (SSc). In this paper, we present five male patients with SSc, aged 30-48 years. All patients are nonsmokers, and their past m...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0567-4
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:Familial Mediterranean fever (FMF) is a hereditary disease characterized by recurrent attacks of fever with peritonitis, arthritis, pleuritis or erysipelas-like rash. It is unclear what effects of FMF itself on endocrine system and hormones are. None of the FMF patients without amyloidosis have been reported ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-005-0083-3
更新日期:2006-07-01 00:00:00
abstract::Behçet's disease (BD) related amyloidosis is relatively rare. Serum amyloid A protein (SAA) protein gene polymorphism is one of the factors implicated in the pathogenesis of AA type amyloidosis. The aim of this study is to investigate SAA1 gene polymorphism in different patient groups: (1) BD related amyloidosis, (2) ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0435-7
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:The relationship between rheumatoid arthritis (RA) and the risk of leukemia was still controversial. This study aimed to assess the risk of leukemia in patients with rheumatoid arthritis by systematic review and meta-analysis. METHODS:Relevant studies were identified by searching PubMed, Embase, Cochrane Li...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05396-7
更新日期:2020-09-17 00:00:00
abstract::Osteonecrosis (ON) is a clinical entity characterized by death of bone marrow and trabecular bone as a result of disruption of blood supply to the bone. The antiphospholipid (APL) syndrome is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with APL antibodies. The involvement ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0716-9
更新日期:2008-02-01 00:00:00