Abstract:
:The aim of this study was to evaluate whether corticosteroid use is the etiological agent in acute pancreatitis in patients with systemic lupus erythematosus, or whether it is related to the underlying connective tissue disorder. Hospital admissions at Thomas Jefferson University Hospital between 1982 and 2002 that carried the dual diagnosis of systemic lupus erythematosus and pancreatitis were identified, and demographic data, clinical interventions and parameters of clinical progression of their disease were identified. From 2947 admissions with systemic lupus erythematosus 25 (0.85%) were diagnosed as having acute pancreatitis; 76% of cases had active systemic lupus erythematosus on presentation, with an average of 4.4 organ involvement, and a clustering of renal disease (56%), pleural effusion (48%) and arthritis (44%) in these patients. Fifteen patients with active disease and three whose disease was inactive received increased doses of corticosteroids, and four active cases and one inactive one stayed on the same doses. Two inactive patients received no corticosteroids before or after the diagnosis of pancreatitis. Eighty-two percent of patients had clinical and laboratory improvement on the higher or maintenance dose of corticosteroids. We therefore concluded that acute pancreatitis is a rare manifestation of systemic lupus erythematosus, and corticosteroids do not appear to be the etiological agent.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Derk CT,DeHoratius RJdoi
10.1007/s10067-003-0793-3subject
Has Abstractpub_date
2004-04-01 00:00:00pages
147-51issue
2eissn
0770-3198issn
1434-9949journal_volume
23pub_type
杂志文章abstract:OBJECTIVE:To evaluate and compare the diagnostic test accuracy of magnetic resonance imaging (MRI) and ultrasound (US) for bone erosion in rheumatoid arthritis (RA) patients for a specific and efficient diagnostic recommendation. METHOD:To evaluate the diagnostic accuracy, the sensitivity, specificity, area under the ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10067-019-04825-6
更新日期:2020-04-01 00:00:00
abstract::In a patient suffering from rheumatoid arthritis, we report the first simultaneous occurrence of two side effects of low-dose methotrexate: an acute megaloblastic anaemia and a pneumonitis. A combination of methotrexate suspension, folinic acid and corticosteroids led to recovery. The correlation between the haematolo...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02231787
更新日期:1993-12-01 00:00:00
abstract::Up to now, there is no uniformly accepted treatment for avascular necrosis (AN) that alleviates pain and retards its progression. The aim of clinical and surgical treatments is usually only to improve blood support in the avascular area. The objective of the present study was to make a systematic review of the use of ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-008-0861-9
更新日期:2008-06-01 00:00:00
abstract::We describe the case of a patient with anticentriole antibody-positive scleroderma spectrum disorder (SSD) who developed pulmonary hypertension. A 54-year-old woman had noticed Raynaud's phenomenon and digital ulcers during the winter for the past 10 years. Although sclerodactyly was not present, digital ulcers, swell...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-004-0871-1
更新日期:2004-06-01 00:00:00
abstract::The authors report the case of a 54-year-old man suffering from steroid-induced osteoporosis, who presented with severe oral ulcerations due to sucking alendronate tablets instead of swallowing them. The misuse of alendronate in this case, underlies the risk of direct mucosal injury with this drug. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670050116
更新日期:1999-01-01 00:00:00
abstract::As part of a larger body of work to develop a rheumatology priority referral score, a literature review was conducted. The objective of the literature review was to identify preexisting priority-setting, triage, and referral tools/scales developed to guide referrals from primary care to specialist care/consultation us...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0938-5
更新日期:2008-11-01 00:00:00
abstract::Intussusception is characterized by one segment of the gastrointestinal tract telescoping into the lumen of the adjacent segment; it is rarely reported in systemic lupus erythematosus (SLE), and the condition can be threatening. Only four cases of intussusception with SLE have been reported in literature. Here, we des...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-017-3879-z
更新日期:2018-01-01 00:00:00
abstract::Evidence for Chagas disease reactivation (CDR) in rheumatologic patients under rheumatologic treatments (RTs) is scarce. To screen and follow-up patients with rheumatic diseases and concomitant Chagas disease under RT to detect CDR and to describe a possible relationship between CDR and specific RT. An observational, ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-021-05581-2
更新日期:2021-01-12 00:00:00
abstract::Subcutaneous nodules are the most common conspicuous extra-articular manifestation of rheumatoid arthritis (RA). Cardiovascular disease (CVD) is the leading cause of death in patients with RA. The objective of this study is to examine the possibility of a relationship between subcutaneous nodules and "first ever" card...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3032-9
更新日期:2015-10-01 00:00:00
abstract::Shoulder pain may occur as a secondary symptom to a wide range of conditions, including rotator cuff disorders, glenohumeral osteoarthritis, or adhesive capsulitis. One common factor linking these diseases is inflammation. Understanding the role of inflammation in shoulder disorders can help physicians to manage and t...
journal_title:Clinical rheumatology
pub_type: 杂志文章,收录出版,评审
doi:10.1007/s10067-009-1109-z
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are rare small to medium-size vessel systemic diseases. As their clinical picture, organ involvement, and factors influencing outcome may differ between countries and geographical areas, we decided to describe a large cohort of Polish AA...
journal_title:Clinical rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1007/s10067-019-04538-w
更新日期:2019-09-01 00:00:00
abstract::Osteonecrosis (ON) is a clinical entity characterized by death of bone marrow and trabecular bone as a result of disruption of blood supply to the bone. The antiphospholipid (APL) syndrome is characterized by arterial and/or venous thrombosis and pregnancy morbidity in association with APL antibodies. The involvement ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0716-9
更新日期:2008-02-01 00:00:00
abstract::We report three cases of tricho-rhino-phalangeal syndrome (TRPS) type I in a Belgian family. They presented typical characteristics such as a pear-shaped nose, and short, deformed fingers with cone-shaped epiphyses of some middle phalanges of the hands. Hair growth was practically normal in our patients, except for so...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02201022
更新日期:1987-06-01 00:00:00
abstract::Fragile X mental retardation 1 (FMR1) premutation carriers, who are at risk of having children with fragile X Syndrome, were initially considered as clinically unaffected. However, recent clinical and molecular studies have shifted this point of view. The incidence of premutation in the general population is substanti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2052-y
更新日期:2012-11-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting multiple organs/systems with variable activities. We performed a retrospective study to investigate the relationship of clinical characteristics and complications with SLE activity in Chinese Han population. A cohort of 1,490 SLE inpatients w...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1240-x
更新日期:2009-11-01 00:00:00
abstract::Two cases of late hypophosphatemic osteomalacia are described: a male aged 30 who had the disease since he was 22 and a woman of 23 who had the disease since she was 14. Both presented with myopathy and bone pain, and showed hypophosphatemia, hyperglycinuria, reduced tubular phosphate reabsorption (TPR), increased hyd...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02031617
更新日期:1985-09-01 00:00:00
abstract::This study aimed to compare the diagnostic value of ultrasonography to conventional radiography in detecting osteophytes and erosions in the midfoot joints in patients suffering from inflammatory and non-inflammatory joint disease. Patients with current foot radiographs were included and stratified in two cohorts: inf...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3658-x
更新日期:2017-09-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of manifestations and potential to affect several organ systems. Complications arise from both disease and medications especially glucocorticoids, significantly contributing to overall morbidity and mortality. SLE predominantly affect...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-019-04795-9
更新日期:2020-03-01 00:00:00
abstract::Idiopathic paroxysmal rhabdomyolysis indicating a classical triad of symptoms consisting of muscle pain, weakness, and discolored urine is known as "Meyer-Betz syndrome". It may result in acute renal failure due to precipitation of the myoglobin casts in the tubuli or to the direct toxic effects of myoglobin to the tu...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-005-0091-3
更新日期:2006-11-01 00:00:00
abstract::We investigated, in retrospect, if there were differences in the frequency and types of abdominal surgery between newly diagnosed female fibromyalgia (n = 80) and rheumatoid arthritis (n = 47) patients performed before the formal diagnosis. There was no difference in the total number of abdominal operations between bo...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670050042
更新日期:1999-01-01 00:00:00
abstract::Charcot joint or neuropathic arthropathy is described in certain neurological conditions. We report the case of a man who presented with a swollen ankle 10 days after a long walk, which rapidly progressed to a Charcot joint. A neurological examination revealed areflexia and insensitivity to temperature and pain. Elect...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670050036
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Our aim was to investigate the prevalence value of a high-avidity antinuclear antibody (ANA) of the IgG isotype (HA IgG ANA) compared with that of ANAs of other isotypes in patients with systemic lupus erythematosus (SLE) and to assess the associations of HA IgG ANA with the activity of SLE and lupus nephrit...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05040-4
更新日期:2020-09-01 00:00:00
abstract::Abnormalities in B cell are characteristic feature of primary Sjögren's syndrome (pSS). As FcγRIIb is a key regulator of B cells, the objective of this study is to investigate the role of the inhibitory receptor FcγRIIb in B cells from pSS patients, and whether glucocorticoid can affect B cell subpopulations or FcγRII...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2344-x
更新日期:2013-12-01 00:00:00
abstract::Spontaneous fractures of the sternum are rare but worth knowing as they may simulate acute cardiac and pulmonary emergencies. A case of an insufficiency sternal fracture mimicking myocardial infarction and subsequent anginal pain is presented. The risk factors of this condition, its clinical features and the diagnosti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02207687
更新日期:1995-07-01 00:00:00
abstract::The effect of long-term (18-70 months) chloroquine treatment 250 mg daily, in rheumatoid arthritis (RA) was studied in 20 patients. Sedimentation rates were significantly reduced, as compared to a reference group of 10 RA patients on no treatment of disease modifying anti-rheumatic drugs. Radiographical progression of...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02041561
更新日期:1983-12-01 00:00:00
abstract::It has been well established that, anti-thyroglobulin antibodies (ATG) and anti-microsomal antibodies (AMC) may be present in various thyroid disorders and other systemic autoimmune diseases, including Sjögren's syndrome (SS). However, presence of circulating autoantibodies to thyroid hormones, i.e. both to triiodothy...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670170102
更新日期:2001-01-01 00:00:00
abstract::This study was designed to explore the profile of immune cell subsets, including T, B, natural killer (NK), and NKT cells, in systemic lupus erythematosus (SLE) patients, and to determine their relationships with the clinical index and the effects of cyclophosphamide (CYC) and mycophenolate mofetil (MMF) treatment. SL...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-1958-8
更新日期:2012-06-01 00:00:00
abstract::Severe exacerbation of symptoms following physical activity is characteristic for chronic-fatigue syndrome (CFS) and fibromyalgia (FM). These exacerbations make it understandable for people with CFS and FM to develop fear of performing body movement or physical activity and consequently avoidance behaviour toward phys...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-013-2277-4
更新日期:2013-08-01 00:00:00
abstract::Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare, benign, autoimmune condition characterized by lymphadenopathy, fever, and neutropenia. KFD can frequently mimic various diseases including infection, malignancy, and autoimmune disease. KFD has also been infrequently reported in associa...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0902-4
更新日期:2008-08-01 00:00:00
abstract::We describe two patients with the primary antiphospholipid syndrome who presented with severe hypertension. Renal biopsy specimen provided histologic evidence of intra-renal vascular disease with intravascular microthrombosis and nephrosclerosis, without feature of proliferative glomerulopathy. Accelerated hypertensio...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/BF02243009
更新日期:1994-12-01 00:00:00