Abstract:
:This study aimed to compare the intraobserver and interobserver reliability of three-dimensional (3D) and two-dimensional (2D) power Doppler ultrasonography (PDUS) and to assess the relationship between 3D PDUS and clinical parameters in patients with rheumatoid arthritis (RA). Bilateral second/third metacarpophalangeal joints and second/third proximal interphalangeal joints in 33 patients were examined by both 2D and 3D PDUS. Each joint was given a separate 2D PDUS subjective score (range, 0-3) in a standard manner. The 2D PDUS index is the sum of the scores of all eight joints assessed. 3D PDUS voxel signals were quantitatively analyzed by using computerized voxel counts. Intraobserver reliability was high for both examinations (2D PDUS: ICC = 0.957, 95% confidence interval = 0.818-0.999; 3D PDUS: ICC = 0.998, 95% confidence interval = 0.998-1.000). Interobserver reliability was also high (2D PDUS: ICC = 0.993, 95% confidence interval = 0.806-0.988; 3D PDUS: ICC = 0.999, 95% confidence interval = 0.999-1.000). A significant correlation was found between the 2D PDUS index and 3D PDUS voxel count (r = 0.795; p < 0.001). The 3D PDUS voxel count showed significant correlation with 28 joints Disease Activity Score (DAS28)-erythrocyte sedimentation rate (r = 0.448, p < 0.01) and DAS28-C-reactive protein (r = 0.383, p < 0.05). Our study indicates that the measurement of 3D PDUS may be a valuable tool for predicting disease activity.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Watanabe T,Takemura M,Sato M,Sekine A,Fukuoka D,Seishima M,Shimizu K,Matsuoka Tdoi
10.1007/s10067-011-1811-5subject
Has Abstractpub_date
2012-02-01 00:00:00pages
299-307issue
2eissn
0770-3198issn
1434-9949journal_volume
31pub_type
杂志文章abstract::To identify clinical variables capable of predicting long-term treatment duration of TNF-α inhibition in patients with Behçet's disease (BD)-related uveitis. Demographic, clinical, and therapeutic data were retrospectively collected from BD patients treated with the tumor necrosis factor (TNF)-α blockers infliximab an...
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
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doi:10.1007/BF03342660
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pub_type: 杂志文章,评审
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journal_title:Clinical rheumatology
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journal_title:Clinical rheumatology
pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章
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journal_title:Clinical rheumatology
pub_type: 杂志文章,随机对照试验
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