Abstract:
:The aim of this study was to investigate whether calcium pyrophosphate dihydrate (CPPD) crystals are constantly detectable in sequential synovial fluid (SF) examinations of patients with initially CPPD-positive osteoarthritis (OA). For this purpose, we searched our SF database for CPPD-positive patients, who had two or more SF analyses between 2008 and 2012 to get sequential information. The database contains SF data determined by a standardised procedure. Of 1,878 samples, examined within the defined time period, 60 samples from sequential SF analyses of 23 patients were eligible for this study. The number of examinations ranged from 2 to 7 (median, 2), and the median interval between the first and last arthrocentesis was 12 months (2-43). CPPD crystals were detected in all of the sequentially examined samples according to the defined criterion of positivity. All of the subjects had OA of the knee, with a median Kellgren-Lawrence grade of 3 in the initially performed X-rays, and meniscal calcifications were found in six subjects. In conclusion, our results suggest that CPPD crystals are a regular feature of sequentially examined SF of initially CPPD-positive patients with symptomatic OA of the knee.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Robier C,Neubauer M,Fritz K,Lippitz P,Stettin M,Rainer Fdoi
10.1007/s10067-012-2147-5subject
Has Abstractpub_date
2013-05-01 00:00:00pages
671-2issue
5eissn
0770-3198issn
1434-9949journal_volume
32pub_type
杂志文章abstract::Pauci-immune necrotizing glomerulonephritis is a form of a rapidly progressive glomerulonephritis that is associated with the anti-neutrophil cytoplasmic antibodies (ANCA). ANCA-associated pauci-immune glomerulonephritis may be secondary to rheumatic diseases. We report on a patient with limited cutaneous systemic scl...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-012-2010-8
更新日期:2012-08-01 00:00:00
abstract::The objective of this study was to describe ultrasonography (US) and magnetic resonance imaging (MRI) findings at painful Achilles tendons and entheses in patients with and without spondyloarthropathy (SpA and non-SpA) and healthy control persons (CTRLs). Particularly, we aimed to investigate if any changes differenti...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-012-2111-4
更新日期:2013-03-01 00:00:00
abstract::Transient receptor potential melastatin 7 (TRPM7) is involved in both normal physiological processes and pathology of various diseases. The purpose of this study was to explore the function and underlying mechanisms of TRPM7 channels in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) apoptosis induced by...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2599-x
更新日期:2014-11-01 00:00:00
abstract::We reported a series of ten patients with lupus nephritis (five patients in the relapse phase and five in the remission phase) and measured the macrophage migration inhibitory factor (MIF), an important pro-inflammatory cytokine with probable role in the pathogenesis of many inflammatory diseases, in their urine sampl...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-007-0632-z
更新日期:2007-12-01 00:00:00
abstract::The aim of this study was to analyse microvascular damage and compensatory angiogenesis in skin from patients with systemic sclerosis (SSc) compared with systemic lupus erythematosus (SLE), Raynaud's phenomenon (RP) and healthy controls. Immunohistochemistry was used for skin biopsies (9 SSc, 10 SLE, 9 RP and 12 healt...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-003-0698-1
更新日期:2003-09-01 00:00:00
abstract::Caeruloplasmin (Cp), prealbumin and alpha 2-macroglobulin (alpha 2-M) concentrations in serum were compared in rheumatoid arthritis (RA), osteoarthrosis, ankylosing spondylitis, psoriatic arthritis, Reiter's syndrome, Behçet's syndrome, SLE and normal controls. Cp was significantly elevated (p less than 0.01) in all d...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02201003
更新日期:1987-03-01 00:00:00
abstract::Simultaneous occurrence of subacute cutaneous lupus erythematosus and malignancy has rarely been reported. We report the first case of subacute cutaneous lupus erythematosus associated with Hodgkin's disease. Although our case does not fulfill the criteria of paraneoplastic process, a relationship between the two diso...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02207938
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The association between pyoderma gangrenosum (PG) and rheumatoid arthritis (RA) was not investigated in the setting of controlled studies. The risk of PG among patients with RA is not established. OBJECTIVE:The study aims to evaluate the magnitude of the association between RA and the subsequent development...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05253-7
更新日期:2021-02-01 00:00:00
abstract::Anaerobic bacteria are uncommon pathogens in septic arthritis. We report a case of pyarthrosis of the right hip caused by Fusobacterium nucleatum, following a transient synovitis in an otherwise healthy boy. There are only a few cases involving this species described in the literature. This report illustrates the diff...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670170072
更新日期:2001-01-01 00:00:00
abstract::This study aims to explore the effectiveness of low dose of etanercept (ETN) in patients with ankylosing spondylitis (AS) who achieve a good control of their disease in daily clinical practice. This is a case series of AS patients treated with ETN. According to the judgment of the treating rheumatologist and patient's...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-011-1722-5
更新日期:2011-07-01 00:00:00
abstract::Behçet's disease is a systemic vasculitic syndrome with unknown etiology. The aim of the present study was to compare the Helicobacter pylori seropositivity and cytotoxin associated gene-A status in patients with Behçet's disease. Ninety-one patients with Behçet's disease and 83 age- and sex-matched persons with or wi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0416-x
更新日期:2007-06-01 00:00:00
abstract::A 67-year-old woman, suffering from continuous hemoptysis, was admitted to our hospital where she was managed with mechanical ventilation. Computed tomography of the chest demonstrated bilateral massive alveolar hemorrhage without evidence of infectious disease. She was diagnosed with anti-myeloperoxidase antineutroph...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-006-0355-6
更新日期:2007-07-01 00:00:00
abstract::Joint lavage for knee osteoarthritis is an invasive procedure that can be stressful and painful. We aimed to assess the impact of music therapy on perioperative anxiety, pain and tolerability of the procedure in patients undergoing joint lavage performed with two needles. We randomized all patients diagnosed with knee...
journal_title:Clinical rheumatology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10067-011-1925-9
更新日期:2012-03-01 00:00:00
abstract::At the intersection of atopy and autoimmunity, we present a patient with seronegative rheumatoid arthritis (RA) who developed hypereosinophilia, without evidence of other etiologies, as she became rheumatoid factor (RF) positive. Although the magnitude of eosinophilia in patients with RA has been thought to reflect th...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-014-2566-6
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:This case-control study aimed to analyze the clinical features and determine the expression of type I interferon-induced genes in systemic lupus erythematosus (SLE) patients harboring the CD11b rs1143679 single-nucleotide polymorphism (SNP) and elucidate whether it is involved in the relapses of SLE. METHODS...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05330-x
更新日期:2020-08-12 00:00:00
abstract::Bone mass was measured in 230 subjects with ages ranging from 15 to 54 years (110 males and 120 females), using the radiogrammetric method on the second metacarpal bone. Results of the study show that bone mass increases with age up to 34 years and then decreases, both in males and females, although males have signifi...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208090
更新日期:1995-01-01 00:00:00
abstract::This study shows that N-acetyl-galactosamine and N-acetyl-glucosamine can diminish the production of superoxide anion from cytochalasin-B treated PMNs stimulated with FMLP. Inhibition ranged from 80.9% to 1.8%. N-acetyl-galactosamine was superior to N-acetyl-glucosamine, but both showed their action in a dose-related ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02207968
更新日期:1992-06-01 00:00:00
abstract::PFAPA syndrome is characterized by episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. PFAPA syndrome usually begins in children under 5 years old and normally has self-resolution. The etiology of PFAPA syndrome remains unknown. In this paper, we report the cases of two different famil...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1222-z
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:ABP 798 is a proposed biosimilar to the originator biologic rituximab, an anti-CD20 monoclonal antibody. This comparative clinical study evaluated the pharmacokinetics (PK), safety, and efficacy of ABP 798 versus rituximab reference product (RP) in patients with moderate-to-severe rheumatoid arthr...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05305-y
更新日期:2020-11-01 00:00:00
abstract::This paper presents the first reported case of risedronate-associated scleritis and conducts a review of bisphosphonates and inflammatory eye diseases. A case of scleritis associated with risedronate use in a 73-year-old Chinese woman is reported. The English medical literature was reviewed for bisphosphonates and the...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-012-2035-z
更新日期:2012-09-01 00:00:00
abstract::With the growing awareness of the impact of chronic back pain and axial spondyloarthritis and recent breakthroughs in genetics and the development of novel treatments which may impact best on early disease, the need for markers that can facilitate early diagnosis and profiling those individuals at the highest risk for...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-015-2949-3
更新日期:2015-06-01 00:00:00
abstract::Acute gouty arthritis (AGA) is an auto-inflammatory disease characterized by resolving spontaneously, which suggests that negative feedback loops control inflammatory and immunological responses to monosodium urate (MSU) crystals. By now, the molecular mechanism for spontaneous resolution of acute GA remains unclear; ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-015-3109-5
更新日期:2016-09-01 00:00:00
abstract::Identification of patients with exposure to viral hepatitis is an important part of the care of patients with inflammatory arthritis. This study was conducted to assess the extent of hepatitis B and C screening, and the prevalence of viral hepatitis in a cohort of patients with established rheumatoid arthritis (RA). T...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2612-4
更新日期:2014-12-01 00:00:00
abstract::The aim of the study was to determine the prevalence and factors associated with bursitis/tendonitis disorders in Puerto Ricans with diabetes mellitus (DM). A cross-sectional study was performed in 202 adult Puerto Ricans (100 DM patients and 102 non-diabetic subjects). For each participant, a complete medical history...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-013-2474-1
更新日期:2014-07-01 00:00:00
abstract::The objectives of the study were to investigate short and long-term changes and relations to treatment response of plasma interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), YKL-40, matrix metalloproteinase-3 (MMP-3), and total aggrecan in patients with spondyloarthritis (SpA) treated with tumor necrosis ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1528-x
更新日期:2010-11-01 00:00:00
abstract::We report an adult case of reflex sympathetic dystrophy. In contrast to the usual findings in adults, three phase bone scintigraphy showed decreased bloodflow and bloodpool with hypofixation on delayed steady state bone scan of the affected lower limb. In spite of various therapeutic attempts severe dystrophy develope...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02208035
更新日期:1991-03-01 00:00:00
abstract::Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent self-limited attacks of fever and polyserositis. Reactive amyloid A amyloidosis is the most devastating complication of FMF, and amyloidosis continues to occur in the colchicine era in untreated and noncompliant patients. U...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-012-2009-1
更新日期:2012-08-01 00:00:00
abstract::The aim of this study was to evaluate whether dexibuprofen meets the basic requirements of Dutch General Practitioners (GPs) for acceptance as an analgesic in mild to moderate pain. The available GP treatment standards for mild to moderate pain were analysed. If no treatment standard was available, results from two se...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF03342660
更新日期:2001-11-01 00:00:00
abstract::To compare the efficacy and safety of aceclofenac (AC) and tenoxicam (TX) in the treatment of rheumatoid arthritis (RA), a multicentric parallel, randomized, double-blind trial of three months duration was performed in 292 patients: 145 were randomized to the AC treatment group and 147 to the TX treatment group. The t...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/BF02229644
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:Decreased natural killer (NK) cells have been reported in systemic lupus erythematosus (SLE) patients. However, the role of NK cells in the pathogenesis of SLE is not well understood. In this study, we aimed to characterize NK cell subsets, phenotypes, and cytokine-secreting functions and investigate the cli...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05306-x
更新日期:2020-08-14 00:00:00