The role of the unfolded protein response in axial spondyloarthritis.

abstract：:Patients with Rheumatic diseases (RDs) are at an increased risk of malignancies compared with the general population. The aim of this study was to examine the relative frequency of several cancers in a single homogeneous cohort of patients with different RDs. Patients diagnosed with rheumatoid arthritis (RA), Ankylosi...

journal_title：Clinical rheumatology

authors： Wang HL,Zhou YM,Zhu GZ,Yang Z,Hua BJ

更新日期：2018-01-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...

journal_title：Clinical rheumatology

authors： Birlik M,Demir T,Zeybel M,Akar S,Onen F,Comlekci A,Tunca M,Akkoc N

更新日期：2004-12-01 00:00:00

abstract：INTRODUCTION:Alkaptonuria (AKU) is a rare metabolic disease. The global incidence is 1:100,000 to 1:250,000. However, identification of a founder mutation in a gypsy population from India prompted us to study the prevalence of AKU in this population and to do molecular typing in referred cases of AKU from the rest of I...

journal_title：Clinical rheumatology

authors： Danda S,Mohan S,Devaraj P,Dutta AK,Nampoothiri S,Yesodharan D,Phadke SR,Jalan AB,Thangaraj K,Verma IC,Danda D,Jebaraj I

更新日期：2020-09-01 00:00:00

abstract：:Haemorrhoidal disease (HD) is one of the most common diseases encountered by the clinicians of general surgery. Chronic constipation, pushing during defecation and increased abdominal pressure play an important role in development of haemorrhoidal disease. Patients with ankylosing spondylitis (AS) frequently use the V...

journal_title：Clinical rheumatology

authors： Caglayan M,Türkoğlu A,Oktayoglu P,Yıldız M,Dağlı AZ,Böyük A,Em S,Bozkurt M,Nas K

更新日期：2015-03-01 00:00:00

abstract：:Knee osteoarthritis is a common joint problem leading to an increase of pain and a loss of function in older individuals. The main objective of this study was to evaluate if a participant who was randomly assigned to his preferred group improved his adherence to an effective walking program compared to a participant w...

journal_title：Clinical rheumatology

authors： Loew L,Brosseau L,Kenny GP,Durand-Bush N,Poitras S,De Angelis G,Wells GA

更新日期：2017-07-01 00:00:00

abstract：:Rituximab is a human/murine chimeric anti-CD20 monoclonal antibody. It is largely used to treat B cell malignancies and has become standard in the management of B cell‑mediated diseases such as rheumatoid arthritis and granulomatosis with polyangitis. The effects of rituximab need to be monitored by B cell phenotyping...

journal_title：Clinical rheumatology

authors： Bergantini L,d'Alessandro M,Cameli P,Vietri L,Vagaggini C,Perrone A,Sestini P,Frediani B,Bargagli E

更新日期：2020-05-01 00:00:00

abstract：:Fibromyalgia syndrome (FMS) is characterized by chronic widespread pain and systemic symptoms. The aetiology and pathogenesis of fibromyalgia are not yet fully understood. Blood neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammatory response. Platelet distribution width (PDW) and mean platelet volume (...

journal_title：Clinical rheumatology

authors： Aktürk S,Büyükavcı R

更新日期：2017-08-01 00:00:00

abstract：:Fibrous dysplasia (FD) is a benign skeletal disorder which may affect one or multiple bones. Lesions often involve long bones, ribs, and craniofacial bones and cause pain, fractures, and disfigurement. We describe an adolescent girl with mandibular FD who was successfully treated with bisphosphonates. She presented wi...

journal_title：Clinical rheumatology

authors： Mäkitie AA,Törnwall J,Mäkitie O

更新日期：2008-06-01 00:00:00

abstract：:In patients with rheumatoid arthritis who had symptomatic knee joints at the start of anti-tumor necrosis factor (TNF) therapy, the relationship between local symptoms and knee joint destruction at 94 weeks was retrospectively investigated. Among the patients with rheumatoid arthritis and received anti-TNF therapy, th...

journal_title：Clinical rheumatology

authors： Imagama T,Tanaka H,Tokushige A,Seki K,Sumiura S,Yamamoto M,Nagahiro Y,Taguchi T

更新日期：2013-06-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) is currently used with much enthusiasm for the treatment of many autoimmune diseases, including systemic lupus erythematosus (SLE). Among its various indications, IVIg has also been found to be beneficial in myocarditis, whether or not it is associated with an autoimmune disease (e.g....

journal_title：Clinical rheumatology

authors： Sherer Y,Levy Y,Shoenfeld Y

更新日期：1999-01-01 00:00:00

abstract：:Perforin and granzyme A co-localize in the cytotoxic granules of killer cells like cytotoxic T lymphocytes (CTL). Perforin is the cytolytic pore-forming protein, whereas the function of the homodimeric serine protease granzyme A and other members of the granzyme family is still unclear. Granzyme A-immunoreactive cells...

journal_title：Clinical rheumatology

authors： Nordström DC,Konttinen YT,Sorsa T,Nykanen P,Pettersson T,Santavirta S,Tschopp J

更新日期：1992-12-01 00:00:00

abstract：:Forty-four patients with typical palindromic rheumatism were typed for HLA-A,B,C and DR antigens. The mean duration of follow-up of our patients was 4.0 yrs. (range 1-12 yrs.). During this time 27% of patients showed a seropositivity; 22% of patients developed polyarthritis, 1 patient revealed a Sjögren syndrome and 3...

journal_title：Clinical rheumatology

authors： Barbieri P,Ciompi ML,Menicucci A,Pasero G

更新日期：1988-12-01 00:00:00

abstract：:Spontaneous fractures of the sternum are rare but worth knowing as they may simulate acute cardiac and pulmonary emergencies. A case of an insufficiency sternal fracture mimicking myocardial infarction and subsequent anginal pain is presented. The risk factors of this condition, its clinical features and the diagnosti...

journal_title：Clinical rheumatology

authors： Schapira D,Nachtigal A,Scharf Y

更新日期：1995-07-01 00:00:00

abstract：:A 43-year-old man suffered from migrating then additive arthralgias associated with macroscopic and microscopic cutaneous lesions compatible at first sight with reticular erythematous mucinosis. After nine months, the cutaneous picture evolved into a papular mucinosis. The patient developed "multiple frozen joints" wi...

journal_title：Clinical rheumatology

authors： Dufour JP,Lachapelle JM,Nagant de Deuxchaisnes C,Devogelaer JP,Noel H,Maldague B

更新日期：1986-06-01 00:00:00

abstract：:The Osteoporosis Assessment Questionnaire Short Version (OPAQ-SV) was cross-culturally adapted to measure health-related quality of life in Chinese osteoporotic fracture females and then validated in China for its psychometric properties. Cross-cultural adaptation, including translation of the original OPAQ-SV into Ma...

journal_title：Clinical rheumatology

authors： Zhang YP,Wei HH,Wang W,Xia RY,Zhou XL,Porr C,Lammi M

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:Interstitial lung disease (ILD) is frequent and highly disabling in systemic sclerosis (SSc). Magnetic resonance imaging (MRI) is not routinely used to evaluate the lung, due to poorer spatial resolution compared to high-resolution computed tomography (HRCT). We aimed to compare lung MRI signal ...

journal_title：Clinical rheumatology

authors： Gargani L,Bruni C,De Marchi D,Romei C,Guiducci S,Bellando-Randone S,Aquaro GD,Pepe A,Neri E,Colagrande S,Falaschi F,Moggi-Pignone A,Pingitore A,Matucci-Cerinic M

更新日期：2020-11-07 00:00:00

abstract：:In addition to juxtaarticular osteoporosis, which appears to reflect predominantly local disease mechanisms, more generalized bone loss can occur in rheumatoid arthritis (RA). The aim of this study was to compare bone mineral density (BMD) of the lumbar spine and proximal femur in RA patients versus controls and evalu...

journal_title：Clinical rheumatology

authors： Celiker R,Gökçe-Kutsal Y,Cindas A,Ariyürek M,Renda N,Koray Z,Basgöze O

更新日期：1995-07-01 00:00:00

abstract：:Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia (CREST) syndrome, a limited form of systemic sclerosis, is sometimes complicated by primary biliary cirrhosis (PBC). A 52- and 61-year-old Japanese woman with PBC-CREST overlap syndrome accompanied by Sjögren's syndrome, and Hashi...

journal_title：Clinical rheumatology

authors： Nakamura T,Higashi S,Tomoda K,Tsukano M,Sugi K

更新日期：2007-04-01 00:00:00

abstract：:We investigated, in retrospect, if there were differences in the frequency and types of abdominal surgery between newly diagnosed female fibromyalgia (n = 80) and rheumatoid arthritis (n = 47) patients performed before the formal diagnosis. There was no difference in the total number of abdominal operations between bo...

journal_title：Clinical rheumatology

authors： ter Borg EJ,Gerards-Rociu E,Haanen HC,Westers P

更新日期：1999-01-01 00:00:00

abstract：:Polyarteritis nodosa (PAN) is a necrotising vasculitis of medium-sized vessels of unknown origin. This type of vasculitis is usually systemic, but restriction to a single organ, for example the testis, the appendix or the gall bladder, can occur. Testicular pain or tenderness are frequent clinical features. In this re...

journal_title：Clinical rheumatology

authors： Meeuwissen J,Maertens J,Verbeken E,Blockmans D

更新日期：2008-11-01 00:00:00

abstract：:Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn's disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial ...

journal_title：Clinical rheumatology

authors： Younger J,Parkitny L,McLain D

更新日期：2014-04-01 00:00:00

abstract：:The relationship between ankylosing spondylitis and the recently proposed entity called axial spondyloarthritis with its radiographic and non-radiographic forms that have been defined by the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial spondyloarthritis (axSpA), is currently being de...

journal_title：Clinical rheumatology

authors： Akkoc N,Khan MA

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:The Patient-Rated Elbow Evaluation (PREE) is a joint-specific, self-administered outcome measure used to determine the level of pain and disability in patients with various elbow pathologies. The aim of this study was to cross-culturally adapt the PREE into Turkish (PREE-T) and to test its reliability and ...

journal_title：Clinical rheumatology

authors： Hazar Kanik Z,Pala OO,Karabicak GO,Citaker S

更新日期：2019-11-01 00:00:00

abstract：:CD30/CD30L and CD40/CD40L are molecules from the tumor necrosis factor (TNF) superfamily. They have a major effect on communications between the B and T cells, which leads to control of maturation, proliferation, and apoptosis of those cells. The aim of this study was to compare the levels of a soluble form of CD30 (s...

journal_title：Clinical rheumatology

authors： Ciferská H,Horák P,Hermanová Z,Ordeltová M,Zadrazil J,Tichý T,Scudla V

更新日期：2007-05-01 00:00:00

abstract：:Initial treatment of trapeziometacarpal osteoarthritis (TMO) often consists of intra-articular injection of corticosteroids or hyaluronic acid. Several studies have shown that ultrasound (US)-guided injections demonstrate greater precision and effectiveness when compared to blind techniques. The aim of our study was t...

journal_title：Clinical rheumatology

authors： Di Sante L,Cacchio A,Scettri P,Paoloni M,Ioppolo F,Santilli V

更新日期：2011-09-01 00:00:00

abstract：:Behçet's disease (BD) related amyloidosis is relatively rare. Serum amyloid A protein (SAA) protein gene polymorphism is one of the factors implicated in the pathogenesis of AA type amyloidosis. The aim of this study is to investigate SAA1 gene polymorphism in different patient groups: (1) BD related amyloidosis, (2) ...

journal_title：Clinical rheumatology

authors： Utku U,Dilek M,Akpolat I,Bedir A,Akpolat T

更新日期：2007-06-01 00:00:00

abstract：:Central nervous involvement (CNS) is uncommon manifestation of Wegener's granulomatosis (WG). We are describing a patient with refractory WG with CNS involvement which responded to rituximab. This lady presented with nodular scleritis. Three months later, she developed headache, vision loss with complete opthalmoplegi...

journal_title：Clinical rheumatology

authors： Sharma A,Kumar S,Wanchu A,Lal V,Singh R,Gupta V,Singh S,Gupta A

更新日期：2010-01-01 00:00:00

abstract：:Extensive subcutaneous and muscular calcification developed in a patient having adult-onset dermatopolymyositis (DM-PM) with an 'overlap' connective tissue disease. We wish to emphasize the rarity of calcification in adult onset DM-PM, which is contrary to the generally held impression. ...

journal_title：Clinical rheumatology

authors： Cohen MG,Nash P,Webb J

更新日期：1986-12-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:We hypothesized that mechanical compression of the knee in rheumatoid arthritis (RA) would mobilize occult extractable fluid and improve arthrocentesis success. METHODS:Sixty-seven consecutive knees with RA and 186 knees with OA and were included. Conventional arthrocentesis was performed and s...

journal_title：Clinical rheumatology

authors： Rolle NA,Jan I,Sibbitt WL Jr,Band PA,Haseler LJ,Hayward WA,Muruganandam M,Emil NS,Fangtham M,Bankhurst AD

更新日期：2019-08-01 00:00:00

abstract：:The objective of the study was to analyze the impact of TNF antagonists (TNFa) on the total cholesterol and triglycerides on ankylosing spondylitis (AS) and psoriatic arthritis (PsA). In this single-centre observational study of AS and PsA patients, differences in triglyceride and total cholesterol levels and frequenc...

journal_title：Clinical rheumatology

authors： Maneiro JR,Souto A,Gomez-Reino JJ

更新日期：2017-05-01 00:00:00