Osteoporosis in rheumatoid arthritis: effect of disease activity.

Abstract:

:In addition to juxtaarticular osteoporosis, which appears to reflect predominantly local disease mechanisms, more generalized bone loss can occur in rheumatoid arthritis (RA). The aim of this study was to compare bone mineral density (BMD) of the lumbar spine and proximal femur in RA patients versus controls and evaluate the influence of disease related determinants. Twenty-seven patients with RA and twenty healthy subjects were included in this study. BMD was significantly reduced in RA patients compared with the control group. BMD was correlated with duration of disease, health assessment questionnaire scores, hand grip strength and erythrocyte sedimentation rate. These results support the hypothesis that BMD may be affected by RA related determinants.

journal_name

Clin Rheumatol

journal_title

Clinical rheumatology

authors

Celiker R,Gökçe-Kutsal Y,Cindas A,Ariyürek M,Renda N,Koray Z,Basgöze O

doi

10.1007/BF02207677

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

429-33

issue

4

eissn

0770-3198

issn

1434-9949

journal_volume

14

pub_type

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