Abstract：
:Knee osteoarthritis is a common joint problem leading to an increase of pain and a loss of function in older individuals. The main objective of this study was to evaluate if a participant who was randomly assigned to his preferred group improved his adherence to an effective walking program compared to a participant who did not receive his preferred group. This was a 9-month pilot randomized clinical trial, based on a patient treatment preferences design. The 69 eligible participants had a diagnosis of knee osteoarthritis. Participants were randomized to one of two groups: a supervised community-based or unsupervised walking program, based on the Ottawa Panel guidelines. At 6 months, participants who expressed a preference, either for the supervised or unsupervised program, and who were assigned to their preferred choice of program showed significantly higher adherence to walking sessions (supervised 60.7 ± 12.3%, P < 0.0001; unsupervised 43.1 ± 12.1%, P = 0.03), compared to the participants who did not obtain their preferred choice of program. After 9 months, significant improvements were shown according to the level of stiffness evaluated with the WOMAC (P = 0.01) and the functional status assessed with the Timed Up and GO Test (P = 0.04), among the adherent participants who obtained their preference, as compared to those who did not receive their preference. We show this approach promotes long-term adherence to a community-based walking program, while ensuring the maintenance of clinical benefits of walking, among older adults susceptible to avoid or not properly engage in physical activity.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Loew L,Brosseau L,Kenny GP,Durand-Bush N,Poitras S,De Angelis G,Wells GAdoi
10.1007/s10067-017-3606-9subject
Has Abstractpub_date
2017-07-01 00:00:00pages
1607-1616issue
7eissn
0770-3198issn
1434-9949pii
10.1007/s10067-017-3606-9journal_volume
36pub_type
杂志文章,随机对照试验abstract：:The prostaglandin series of bioactive compounds is formed by the interaction of two distinct but related enzymes, cyclo-oxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is a constitutive form which is present mainly in the gastric mucosa, kidney and platelets. COX-2 is mainly an inducible form, although also to...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s100670070024
更新日期：2000-01-01 00:00:00
abstract：:The immunoinflammatory pathogenesis of juvenile chronic arthritis (JCA) involves the activation of many pathways including various cytokines. We have evaluated the levels of interleukin(IL)-1, IL-6 and IL-8 in 29 JCA patients. The age range was 1-16 with a mean of 10.1. A disease activity score was developed on the ba...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02247847
更新日期：1997-03-01 00:00:00
abstract：:Spontaneous fractures of the sternum are rare but worth knowing as they may simulate acute cardiac and pulmonary emergencies. A case of an insufficiency sternal fracture mimicking myocardial infarction and subsequent anginal pain is presented. The risk factors of this condition, its clinical features and the diagnosti...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207687
更新日期：1995-07-01 00:00:00
abstract：:Hypercalcaemia is a common electrolyte abnormality. The vast majority of patients will be shown to have either hyperparathyroidism or malignancy. In less than 10% of patients other, less common causes of hypercalcaemia will be present. Systemic lupus erythematosus is a very rare cause of hypercalcaemia. It may be asso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670170088
更新日期：2001-01-01 00:00:00
abstract：:The aim of the is study is to examine the role of serum substance P (SP) levels as a simple biomarker for rheumatoid arthritis (RA) disease activity, its correlation with other markers of disease activity, and with selected clinical parameters. The study comprised 90 RA patients and 24 healthy controls. RA activity wa...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3929-6
更新日期：2018-04-01 00:00:00
abstract：:Anti-CCP (cyclic citrullinated peptide) is considered the most useful laboratory tool in the diagnosis of rheumatoid arthritis (RA). Some authors have also found this autoantibody in patients with scleroderma (SSc). The study aimed to investigate the prevalence of anti-CCP antibodies in SSc patients from Southern Braz...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1930-z
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:Patients with axial spondyloarthritis (SpA) are subjected to elevated cardiovascular risks, but assessment of early myocardial damage and clinical risk stratification remained obscure. The aim of this study was to evaluate the prognostic value of speckle-tracking strain analysis and serum high-sensitivity tro...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05112-5
更新日期：2020-11-01 00:00:00
abstract：:Dual-energy X-ray absorptiometry (DXA) is actually considered as one of the most appropriate techniques for measuring bone mineral content (BMC) and bone mineral density (BMD). An anthropomorphic phantom and a 25-year-old girl were repeatedly measured, 160 times and 50 times respectively, over an 18-month period to in...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02214940
更新日期：1995-03-01 00:00:00
abstract：:Four patients with rheumatoid nodulosis are here described, together with a review of cases reported to date in the literature. This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign cour...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207201
更新日期：1992-09-01 00:00:00
abstract：:Oxidative stress was related with carpal tunnel syndrome (CTS). We aimed to clarify the associations between glutathione S-transferase (GST)M1, GSTT1 and GSTP1-Ile105Val polymorphisms and CTS. One hundred-forty patients with CTS and 97 healthy controls were enrolled in this study. Tinel and Phalen signs were noted as ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2855-0
更新日期：2016-05-01 00:00:00
abstract：:We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207092
更新日期：1992-03-01 00:00:00
abstract：OBJECTIVES:To test the psychometric properties of the United Kingdom's Commissioning for Quality in Rheumatoid Arthritis Patient-Reported Experience Measure (CQRA-PREM) in patients with spondyloarthritis (SpA) and rheumatoid arthritis (RA) and to implement this questionnaire in daily practice in the Netherlands. METHO...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05076-6
更新日期：2020-10-01 00:00:00
abstract：INTRODUCTION:The Patient-Rated Elbow Evaluation (PREE) is a joint-specific, self-administered outcome measure used to determine the level of pain and disability in patients with various elbow pathologies. The aim of this study was to cross-culturally adapt the PREE into Turkish (PREE-T) and to test its reliability and ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04665-4
更新日期：2019-11-01 00:00:00
abstract：INTRODUCTION/OBJECTIVES:The primary objective was to evaluate the impact of an in-department pharmacist on the prevention of drug iatrogenesis in a rheumatology department. Secondary objectives were to determine (i) if medication history discrepancies were detected more frequently in the elderly or not, and (ii) if the...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05138-9
更新日期：2021-01-01 00:00:00
abstract：:Yao syndrome (YAOS), formerly named NOD2-associated autoinflammatory disease, is a periodic disease characterized by fever, dermatitis, polyarthritis, distal extremity swelling, and gastrointestinal and sicca-like symptoms associated with specific NOD2 sequence variants. All patients in the literature were Caucasians....
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-018-4274-0
更新日期：2018-12-01 00:00:00
abstract：:Either total hip arthroplasty (THA), total knee arthroplasty (TKA) or both were performed in 105 patients from 1981 to 1994. These patients were experiencing severe joint destruction in the lower extremities due to rheumatoid arthritis (RA). These patients were followed for more than 2 years after their last operation...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF01452259
更新日期：1998-01-01 00:00:00
abstract：:The involvement of brain-derived neurotrophic factor (BDNF) in rheumatoid arthritis (RA) is largely unknown. The distribution of BDNF and its associated receptors, TrkB and p75, in the synovial tissue of patients with RA was examined and contrasted with that in patients with osteoarthritis (OA). Additionally, levels o...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-008-0910-4
更新日期：2008-10-01 00:00:00
abstract：:Type B insulin resistance syndrome is characterized by the formation of autoantibodies against insulin receptors, which can cause severe hyperglycemia and insulin resistance. Systemic lupus erythematosus is the most common underlying diseases of the syndrome. This report details our study of a case involving a Chinese...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-012-2098-x
更新日期：2013-02-01 00:00:00
abstract：:Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3932-y
更新日期：2018-04-01 00:00:00
abstract：:An insufficiency fracture (IF) involving the acetabulum is presented. This fracture occurred in a 67-year-old woman who had been hysterectomized and oophorectomized 27 years earlier for a carcinoma of the uterine cervix, and who had received external pelvic irradiation. This IF location has been rarely described earli...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207215
更新日期：1992-09-01 00:00:00
abstract：:Chronic pediatric musculoskeletal (MSK) conditions are a major cause of morbidity. The burden of pediatric rheumatic diseases in East Africa is largely unknown. The purposes of this study were to estimate frequencies and assess the spectrum of MSK-related diagnoses using ICD-10 diagnostic codes among outpatients at a ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4376-8
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:Tumor necrosis factor inhibitors (anti-TNF) have become the standard treatment for rheumatoid arthritis (RA). However, evidence is inconsistent as to whether RA patients with anti-TNF are associated with an increased risk of non-melanoma skin cancer (NMSC) compared with those without anti-TNF. We performed a ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-019-04865-y
更新日期：2020-03-01 00:00:00
abstract：:Fragile X mental retardation 1 (FMR1) premutation carriers, who are at risk of having children with fragile X Syndrome, were initially considered as clinically unaffected. However, recent clinical and molecular studies have shifted this point of view. The incidence of premutation in the general population is substanti...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-012-2052-y
更新日期：2012-11-01 00:00:00
abstract：:Antibodies to 65Kd heat-shock protein (hsp) of mycobacterium leprae were measured by enzyme-linked immunosorbent assay (ELISA) in the three immunoglobulin classes in paired sera and synovial fluids of patients with rheumatoid arthritis (RA). Titers of anti-hsp antibody were expressed by optical density (OD) values for...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02249023
更新日期：1994-06-01 00:00:00
abstract：:Heart rate variability (HRV) gives information about sympathetic parasympathetic autonomic balance. Our purpose was to determine whether HRV is abnormal in patients with Sjögren's syndrome. In 16 patients with Sjögren's syndrome and 30 matched controls, a short time analysis of HRV was performed for both the frequency...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/pl00011180
更新日期：2000-01-01 00:00:00
abstract：:To describe clinical and epidemiological data of Behçet's disease (BD) in Brazil, we retrospectively reviewed records of all patients seen between 2006 and 2007 at the BD outpatient clinic of University of Sao Paulo. One hundred and six patients fulfilled the International Study Group for Behçet's Disease diagnostic c...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-008-1081-z
更新日期：2009-05-01 00:00:00
abstract：:Chronic hepatitis C virus (HCV) viremia has been known to provoke a plethora of autoimmune syndromes referred to as extrahepatic manifestations of chronic HCV infection. Aim of the current study was to assess the prevalence of rheumatologic manifestations among Egyptians with hepatitis C infection and its' association...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1463-x
更新日期：2010-12-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) is the most common inherited periodic fever syndrome characterized by recurrent episodes of serositis. Recently, a few studies have suggested that FMF is related to increased risk of atherosclerosis. Mean platelet volume (MPV) is a marker of platelet activation. Larger platelets are ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1148-5
更新日期：2009-08-01 00:00:00
abstract：:Subcutaneous rheumatoid nodules occur commonly in advanced cases of rheumatoid arthritis and are the most common extra-articular lesion of this disease. We present a case of a very unusual giant rheumatoid nodule that developed on the lateral side of a knee. The case was devoid of systemic symptoms of arthritis and th...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-004-0926-3
更新日期：2004-10-01 00:00:00
abstract：:The purpose of the study was to assess the 1-year outcome of definitive reactive arthritis (ReA) after a waterborne outbreak. A cohort of 21 patients (15 females and 6 males, median age 54 years) with ReA related to an extensive waterborne outbreak in Finland was clinically followed-up by rheumatologists with visits a...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-013-2247-x
更新日期：2013-08-01 00:00:00
