Outcomes for patients undergoing one or more total hip and knee arthroplasties.


:Either total hip arthroplasty (THA), total knee arthroplasty (TKA) or both were performed in 105 patients from 1981 to 1994. These patients were experiencing severe joint destruction in the lower extremities due to rheumatoid arthritis (RA). These patients were followed for more than 2 years after their last operation. Eighty-six patients were alive and 19 patients had died at the time of follow-up. The 86 living patients were divided into four groups based on the number of replaced joints. Their pre- and postoperative conditions, including such factors as pain, mobility and disability for the quality of life (QOL), were compared. All of the four groups showed some reduction in pain and disability, and an improvement in ambulation after the operations. The 19 deceased patients were classified into two groups, one including those with multiple (three or four) arthroplasties and the other, those with only a small number (one or two). The mean age at death was lower (55.7+/-6.2 years) in patients with multiple arthroplasties than that (69.1+/-7.5 years) in patients with only a small number of arthroplasties. Secondary diseases from RA, such as amyloidosis, spinal injury and pulmonary fibrosis, were found to be the primary cause of death in patients with multiple arthroplasties. The most important finding in this study is that although RA patients with multiple arthroplasties in the lower extremities improved their QOL, they were still afflicted with secondary diseases derived from RA and experienced complications that could shorten their lifespan.


Clin Rheumatol


Clinical rheumatology


Kageyama Y,Miyamoto S,Ozeki T,Hiyoshi M,Kushida K,Inoue T




Has Abstract


1998-01-01 00:00:00












  • Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases.

    abstract::The objectives of this study are to investigate the prevalence of PAD4 and anti-PAD4 antibodies (Abs) in autoimmune diseases and to clarify their association with anticitrullinated protein antibodies (ACPAs) and shared epitope (SE) in patients with rheumatoid arthritis (RA). Levels of human PAD4 and anti-PAD4 Abs in s...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Umeda N,Matsumoto I,Kawaguchi H,Kurashima Y,Kondo Y,Tsuboi H,Ogishima H,Suzuki T,Kagami Y,Sakyu T,Ishigami A,Maruyama N,Sumida T

    更新日期:2016-05-01 00:00:00

  • The relation of serum vascular endothelial growth factor level with disease duration and activity in patients with rheumatoid arthritis.

    abstract::Vascular endothelial growth factor (VEGF) is known to be involved in the pathogenesis of rheumatoid arthritis (RA). In order to elucidate the association between VEGF levels and RA disease activity, VEGF concentrations were measured in RA patients at different phases and severity levels. Thirty-eight healthy subjects ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Ozgonenel L,Cetin E,Tutun S,Tonbaklar P,Aral H,Guvenen G

    更新日期:2010-05-01 00:00:00

  • Prevalence of osteoporosis in men aged 65-75 in a primary care setting. A practice audit after application of the Canadian 2010 guidelines for osteoporosis screening.

    abstract::Current Canadian osteoporosis guidelines recommend routine bone density screening of men at age 65. The purpose of this study is to determine the prevalence of osteoporosis in men aged 65-75 in after application of screening guidelines. All males aged 65-75 years who attended a large primary care clinic were advised o...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,多中心研究


    authors: Ferrari R

    更新日期:2015-03-01 00:00:00

  • Progress made towards enhancement of rheumatology education and practice in Zambia: review of an ILAR-supported project.

    abstract::The burden of non-communicable diseases such as musculoskeletal diseases in the developing world is often overshadowed by the more prevalent infectious diseases. Generally, there is gross underestimation of the burden of rheumatologic disease in the backdrop of scanty or indeed non-existent rheumatology services in th...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Chipeta J,Njobvu P,McGill PE,Bucala R

    更新日期:2014-01-01 00:00:00

  • Mycophenolate mofetil in Takayasu's arteritis.

    abstract::Mycophenolate mofetil (MMf) has recently been reported as a useful alternative immunosuppressive drug in autoimmune diseases. There is paucity of literature on its use in Takayasu's arteritis (TA). The aim of this study was to assess the safety and efficacy of MMf in Asian Indian patients with Takayasu's arteritis. Re...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Goel R,Danda D,Mathew J,Edwin N

    更新日期:2010-03-01 00:00:00

  • Tailored approach to early psoriatic arthritis patients: clinical and ultrasonographic predictors for structural joint damage.

    abstract::This study aims to identify the clinical predictors of arthritis in patients with psoriasis and to evaluate the use of musculoskeletal ultrasonography (US) as a predictor for inflammatory structural progression in psoriatic patients. Measures of association (odds ratio (OR)) were tested, in a prospective, cohort 1-yea...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: El Miedany Y,El Gaafary M,Youssef S,Ahmed I,Nasr A

    更新日期:2015-02-01 00:00:00

  • Role of cytolytic impairment of natural killer and natural killer T-cell populations in rheumatoid arthritis.

    abstract::Innate immunity has been widely accepted as one of the major cause for the alteration of immune system and progression of autoimmune diseases. Natural killer (NK) cells and natural killer T (NKT) cells have not been explored in clinical studies for their cytolytic components in association with rheumatoid arthritis (R...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Aggarwal A,Sharma A,Bhatnagar A

    更新日期:2014-08-01 00:00:00

  • Angiotensin II type 1 receptor gene polymorphism and serum angiotensin-converting enzyme level in Egyptian children with systemic lupus erythematosus.

    abstract::Angiotensin II, the major effective molecule of the renin-angiotensin system, plays a vital role in the development of systemic lupus erythematosus (SLE). To study angiotensin II type 1 receptor (AT1R) gene polymorphism at (A1166C) in Egyptian children with SLE and its correlation with serum ACE level and SLE manifest...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Shoaib RMS,Hammad A,Yahia S,Elsaid A,Abdel-Malak CA

    更新日期:2018-12-01 00:00:00

  • Treatment of therapy-resistant sarcoidosis with adalimumab.

    abstract::A possible role of tumor necrosis factor alpha (TNFalpha) in the pathomechanism of sarcoidosis must be considered in the analysis of this disorder since elevated concentrations of this cytokine have been found. In addition, TNFalpha expression could be demonstrated in sarcoid granulomata [1]. It is well known that TNF...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Callejas-Rubio JL,Ortego-Centeno N,Lopez-Perez L,Benticuaga MN

    更新日期:2006-07-01 00:00:00

  • Inhibition of transient receptor potential melastatin 7 (TRPM7) channel induces RA FLSs apoptosis through endoplasmic reticulum (ER) stress.

    abstract::Transient receptor potential melastatin 7 (TRPM7) is involved in both normal physiological processes and pathology of various diseases. The purpose of this study was to explore the function and underlying mechanisms of TRPM7 channels in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLSs) apoptosis induced by...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Li X,Wang X,Wang Y,Li X,Huang C,Li J

    更新日期:2014-11-01 00:00:00

  • Infective endocarditis complicating rituximab (anti-CD20 monoclonal antibody) treatment in an SLE patient with a past history of Libman-Sacks endocarditis: a case for antibiotic prophylaxis?

    abstract::We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Armstrong D,Wright S,McVeigh C,Finch M

    更新日期:2006-07-01 00:00:00

  • Hyperimmunoglobulinemia D syndrome in an Arab child.

    abstract::Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described we...

    journal_title:Clinical rheumatology

    pub_type: 信件


    authors: Hammoudeh M

    更新日期:2005-02-01 00:00:00

  • Association between Takayasu arteritis and latent or active Mycobacterium tuberculosis infection: a systematic review.

    abstract::Takayasu arteritis (TA) is a granulomatous vasculitis of large vessels with unknown aetiopathogenesis. An association between TA and tuberculosis (TB) has been suggested by several authors. The objective of this study was to perform a systematic review of the literature on the association of Mycobacterium tuberculosis...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Pedreira ALS,Santiago MB

    更新日期:2020-04-01 00:00:00

  • Gynaecologic history in systemic sclerosis.

    abstract::The aim of the study was to analyse the gynaecologic history of 150 Brazilian patients with systemic sclerosis (SSc) by comparing the outcome of the pregnancies before and after disease onset and in the two clinical variants of SSc, as well as to assess the effects of the pregnancy on the progress of the disease. A re...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Sampaio-Barros PD,Samara AM,Marques Neto JF

    更新日期:2000-01-01 00:00:00

  • Patient-reported involvement of the eighth cranial nerve in giant cell arteritis.

    abstract:INTRODUCTION:The frequency of eighth nerve lesions in patients with giant cell arteritis (GCA) has rarely been examined. However, sudden onset deafness has been recorded as a presenting feature of GCA on several occasions. This study sought to establish how common this and other symptoms of eighth nerve involvement are...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Saravanan V,Pugmire S,Smith M,Kelly C

    更新日期:2019-12-01 00:00:00

  • High resolution computed tomography for the evaluation of lung involvement in 101 patients with scleroderma.

    abstract::The aim of the study was to investigate the pulmonary parenchymal abnormalities by high resolution computed tomography (HRCT) in patients with various forms of scleroderma. Three scans were performed sequentially in all cases: one at the level of aortic arch, one at the tracheal carina and one 1-2 cm above the diaphra...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Dévényi K,Czirják L

    更新日期:1995-11-01 00:00:00

  • A case of recurrent pancreatitis due to hyperlipidemia misdiagnosed as familial Mediterranean fever.

    abstract::Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...

    journal_title:Clinical rheumatology

    pub_type: 信件


    authors: Birlik M,Demir T,Zeybel M,Akar S,Onen F,Comlekci A,Tunca M,Akkoc N

    更新日期:2004-12-01 00:00:00

  • Tacrolimus as a reinforcement therapy for a patient with MPO-ANCA-associated diffuse alveolar hemorrhage.

    abstract::A 67-year-old woman, suffering from continuous hemoptysis, was admitted to our hospital where she was managed with mechanical ventilation. Computed tomography of the chest demonstrated bilateral massive alveolar hemorrhage without evidence of infectious disease. She was diagnosed with anti-myeloperoxidase antineutroph...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Kawasaki S,Nakamura H,Honda E,Iwanaga N,Kawakami A,Ida H,Origuchi T,Honda S,Tsuchihashi Y,Yoshimine H,Eguchi K

    更新日期:2007-07-01 00:00:00

  • Spondyloarthritis in women: differences in disease onset, clinical presentation, and Bath Ankylosing Spondylitis Disease Activity and Functional indices (BASDAI and BASFI) between men and women with spondyloarthritides.

    abstract::The aim of this study is to assess the gender differences in spondyloarthritides (SpAs) in terms of disease onset, clinical presentation, and the Bath Ankylosing Spondylitis Disease Activity and Functional indices (BASDAI and BASFI). We analysed data from a predominantly female cohort. Five hundred and 16 patients (ma...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Roussou E,Sultana S

    更新日期:2011-01-01 00:00:00

  • Adrenal axis functions in patients with familial Mediterranean fever.

    abstract:OBJECTIVE:Familial Mediterranean fever (FMF) is a hereditary disease characterized by recurrent attacks of fever with peritonitis, arthritis, pleuritis or erysipelas-like rash. It is unclear what effects of FMF itself on endocrine system and hormones are. None of the FMF patients without amyloidosis have been reported ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Sav T,Ozbakir O,Kelestimur F,Gursoy S,Baskol M,Kula M,Dundar M

    更新日期:2006-07-01 00:00:00

  • Anaesthetic risks in osteoarticular disorders.

    abstract::Anaesthesia in patients with either treated or untreated osteo-articular disorders poses a number of specific problems. The authors deal with risks resulting from mechanical deformities produced by these disorders, by the involvement of a large number of functional systems, by changes in the immune status of such pati...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Reginster JY,Damas P,Franchimont P

    更新日期:1985-03-01 00:00:00

  • A Chinese case series of Yao syndrome and literature review.

    abstract::Yao syndrome (YAOS), formerly named NOD2-associated autoinflammatory disease, is a periodic disease characterized by fever, dermatitis, polyarthritis, distal extremity swelling, and gastrointestinal and sicca-like symptoms associated with specific NOD2 sequence variants. All patients in the literature were Caucasians....

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,评审


    authors: Yang X,Wu D,Li J,Shen M,Zhang W

    更新日期:2018-12-01 00:00:00

  • Combination therapy with Bosentan and Sildenafil improves Raynaud's phenomenon and fosters the recovery of microvascular involvement in systemic sclerosis.

    abstract::The aim of this study was to evaluate in systemic sclerosis (SSc) retrospectively the effect of Bosentan and Sildenafil and their combination on Raynaud's phenomenon (RP), function, and capillaroscopic patterns. One hundred and twenty-three SSc patients (mean age ± sd, 57.69 ± 14.07 years) were retrospectively evaluat...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Bellando-Randone S,Lepri G,Bruni C,Blagojevic J,Radicati A,Cometi L,De Paulis A,Matucci-Cerinic M,Guiducci S

    更新日期:2016-01-01 00:00:00

  • Faraway from the silk route: demographic and clinical features of Behçet's disease in 106 Brazilian patients.

    abstract::To describe clinical and epidemiological data of Behçet's disease (BD) in Brazil, we retrospectively reviewed records of all patients seen between 2006 and 2007 at the BD outpatient clinic of University of Sao Paulo. One hundred and six patients fulfilled the International Study Group for Behçet's Disease diagnostic c...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Neves FS,Caldas CA,Lage LV,Goldenstein-Schainberg C,Gonçalves CR

    更新日期:2009-05-01 00:00:00

  • Erosive arthritis in a patient with amyloid arthropathy.

    abstract::Amyloid arthropathy is said to be distinguished roentgenographically from rheumatoid arthritis by the absence of joint space narrowing and the absence of articular erosions. We present a patient with multiple myeloma with swelling, stiffness and firm synovial thickening of the wrists, metacarpophalangeal joints and pr...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Leonard PA,Clegg DO,Lee RG

    更新日期:1985-06-01 00:00:00

  • Bone mass in Zaireans: radiogrammetric determination.

    abstract::Bone mass was measured in 230 subjects with ages ranging from 15 to 54 years (110 males and 120 females), using the radiogrammetric method on the second metacarpal bone. Results of the study show that bone mass increases with age up to 34 years and then decreases, both in males and females, although males have signifi...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Kabeya JM,Mbuyi Muamba JM,Tozin R,Dequeker J

    更新日期:1995-01-01 00:00:00

  • The effect of total hip replacement on employment in patients with ankylosing spondylitis.

    abstract::Although total hip replacement (THR) has been proven to be effective, the effect of THR on employment in ankylosing spondylitis (AS) in Chinese population is still unknown. We aimed to demonstrate whether or not patients with AS returned to work following THR and factors associated with the work ability after THR. We ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: He C,He X,Tong W,Zheng W,Zhang T,Zhao J,Xu W

    更新日期:2016-12-01 00:00:00

  • Comparative tolerability of paracetamol, aspirin and ibuprofen for short-term analgesia in patients with musculoskeletal conditions: results in 4291 patients.

    abstract::The aim of this blinded, randomised, multicentre study was to compare the tolerability of aspirin, paracetamol and ibuprofen in common pain resulting from musculoskeletal conditions (MSC) in general practice with patients with other non-MSC pain conditions. Patients took aspirin, paracetamol (both up to 3g daily) or i...

    journal_title:Clinical rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Le Parc JM,Van Ganse E,Moore N,Wall R,Schneid H,Verrière F

    更新日期:2002-02-01 00:00:00

  • Correction to: Comparison of 8-year knee osteoarthritis progression in 2 siblings: a case-based review.

    abstract::The original version of this article was revised due to a retrospective Open Access order. ...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章,已发布勘误


    authors: Gourlay ML,Gourlay LL

    更新日期:2020-10-01 00:00:00

  • Association between three non-insulin-based indexes of insulin resistance and hyperuricemia.

    abstract:OBJECTIVE:The association between hyperuricemia and insulin resistance (IR) has been demonstrated by many studies, but the traditional IR indexes are too impractical to be used in clinical practice for the recognition of the IR state in individuals with hyperuricemia. Therefore, we aimed to further investigate the asso...

    journal_title:Clinical rheumatology

    pub_type: 杂志文章


    authors: Liu XZ,Xu X,Zhu JQ,Zhao DB

    更新日期:2019-11-01 00:00:00