Abstract：
:CD30/CD30L and CD40/CD40L are molecules from the tumor necrosis factor (TNF) superfamily. They have a major effect on communications between the B and T cells, which leads to control of maturation, proliferation, and apoptosis of those cells. The aim of this study was to compare the levels of a soluble form of CD30 (sCD30) and a soluble ligand CD40 (sCD40L) in patients with systemic lupus erythematosus (SLE) (n=65) and healthy controls (sCD30 n=20, sCD40L n=10) with other parameters of SLE activity. Patients were divided into subgroups according to presence or absence of lupus nephritis (LN; 33 with LN, 32 without LN). The serum levels of selected parameters were assessed also in the subgroups with low active disease characterized by European Lupus Activity Measure (ECLAM) at most 3(n=29) and active disease with ECLAM more than 3 (n=36). The serum levels of sCD30 were 66.0+/-40.2 UI/ml in the whole group. The mean serum levels were 60.0+/-45.2 UI/ml in the subgroups with LN, 67.1+/-38.9 UI/ml in the subgroup without LN, 80.2+/-51.9 UI/ml in the subgroup with active disease, 55.4+/-24.1 UI/ml in the subgroup with low active disease, and finally, 40.1+/-19.2 U/ml in the controls. Significant differences were found between the SLE patients and controls (p=0.0001) and between the active and nonactive groups (p=0.002). A correlation was found between levels of CD30 and ECLAM (r=0.25, p journal_name journal_title authors doi subject pub_date pages issue eissn issn journal_volume pub_type
abstract：:Hypercalcaemia is a common electrolyte abnormality. The vast majority of patients will be shown to have either hyperparathyroidism or malignancy. In less than 10% of patients other, less common causes of hypercalcaemia will be present. Systemic lupus erythematosus is a very rare cause of hypercalcaemia. It may be asso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670170088
更新日期：2001-01-01 00:00:00
abstract：:This study aimed to determine the frequency of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) antibodies in a cohort of patients with palindromic rheumatism (PR) and to find determinants for progression to rheumatoid arthritis (RA). All new cases of PR (n=90) were included prospectively and followed up ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2569-3
更新日期：2014-06-01 00:00:00
abstract：:Juvenile idiopathic arthritis (JIA) is the most common chronic arthritis of childhood. Currently, it is characterized by seven categories. The enthesitis-related arthritis (ERA) category usually affects boys older than 6 years and presents with lower limb asymmetrical arthritis associated with enthesitis. Later, these...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-3029-4
更新日期：2015-11-01 00:00:00
abstract：:The aim of this study was to assess the role of oxidative stress in the pathogenesis of Henoch-Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase (ARYL), and paraoxonase (PON) as antioxidant enzymes and serum malondialdehyde (MDA) level as an indicator of lipid peroxidation, together wi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0671-5
更新日期：2008-02-01 00:00:00
abstract：INTRODUCTION/OBJECTIVE:Knee alignment and anterior cruciate ligament (ACL) injury are risk factors for knee osteoarthritis (OA). The objective was to examine interactions between knee alignment and ACL status on cartilage volume loss in participants with or at risk of knee OA. METHOD:Participants were from the Osteoar...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04759-z
更新日期：2019-12-01 00:00:00
abstract：:Diffuse systemic sclerosis and the related syndromes were diagnosed in 115 patients during 1977-1987. Sixty-nine patients were available for clinical evaluation and analysis. These included 46 patients with diffuse systemic sclerosis, 2 with limited cutaneous systemic sclerosis, 2 with linear scleroderma, 18 with over...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207649
更新日期：1991-06-01 00:00:00
abstract：:Acute gouty arthritis (AGA) is an auto-inflammatory disease characterized by resolving spontaneously, which suggests that negative feedback loops control inflammatory and immunological responses to monosodium urate (MSU) crystals. By now, the molecular mechanism for spontaneous resolution of acute GA remains unclear; ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-015-3109-5
更新日期：2016-09-01 00:00:00
abstract：:Two cases of Paget's sarcoma of bone are described. The first one is mainly characterized by the almost simultaneous degeneration of the only two existing locations of the underlying Paget's disease. The second case is one of monostotic Paget's disease of the scapula disclosed by the malignant degeneration. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02031268
更新日期：1984-12-01 00:00:00
abstract：:Churg-Strauss syndrome (CSS) is a rare, systemic, necrotizing, small- and middle-sized vessel vasculitis which is accompanied by blood eosinophilia, eosinophil infiltration of various tissues, and bronchial asthma. The lungs are the organs most often involved in CSS. The aim of this study was a retrospective evaluatio...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1530-3
更新日期：2010-10-01 00:00:00
abstract：:Heart rate variability (HRV) gives information about sympathetic parasympathetic autonomic balance. Our purpose was to determine whether HRV is abnormal in patients with Sjögren's syndrome. In 16 patients with Sjögren's syndrome and 30 matched controls, a short time analysis of HRV was performed for both the frequency...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/pl00011180
更新日期：2000-01-01 00:00:00
abstract：:Antibodies to beta(2)-glycoprotein I (anti-beta(2)-GPI) have been reported to have stronger association with clinical antiphospholipid syndrome (APS) than anticardiolipin antibodies (aCL) and lupus anticoagulant (LAC). We investigated the sensitivity and specificity of ELISA for anti-beta(2)-GPI in Thai systemic lupus...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0566-5
更新日期：2007-10-01 00:00:00
abstract：:Calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia (CREST) syndrome, a limited form of systemic sclerosis, is sometimes complicated by primary biliary cirrhosis (PBC). A 52- and 61-year-old Japanese woman with PBC-CREST overlap syndrome accompanied by Sjögren's syndrome, and Hashi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-0178-x
更新日期：2007-04-01 00:00:00
abstract：:The outbreak of SARS-CoV-2 has changed the habits and lives of people worldwide. Patients affected by systemic sclerosis (SSc) experienced constant fear because of their immunocompromised status. The aim of this study was to investigate the prevalence of SARS-CoV-2 infection and to analyze the lifestyle changes in a s...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05504-7
更新日期：2020-11-14 00:00:00
abstract：:The autoantibody profiles in New Zealand systemic sclerosis patients have not previously been reported. The aim of this study was to evaluate the autoantibody profiles of patients in the Waikato Hospital Systemic Sclerosis Clinic cohort. The EUROLINE (IgG) Systemic Sclerosis panel test kit (which tests for Scl-70, CEN...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-015-2981-3
更新日期：2015-11-01 00:00:00
abstract：:Initial treatment of trapeziometacarpal osteoarthritis (TMO) often consists of intra-articular injection of corticosteroids or hyaluronic acid. Several studies have shown that ultrasound (US)-guided injections demonstrate greater precision and effectiveness when compared to blind techniques. The aim of our study was t...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1730-5
更新日期：2011-09-01 00:00:00
abstract：:The aim of the study was to present a method enabling a reduction of the number of measurements when quantifying isokinetic muscle strength (IMS), and to describe an expression for IMS which is independent of measuring conditions. IMS is a measure of muscle strength used to categorise patients and to assess changes ov...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/pl00011211
更新日期：2001-01-01 00:00:00
abstract：:A 62-year-old man who suffered from severe deforming arthritis, secondary to chronic tophaceous gout with multilobular, solid, tender, enlarged subcutaneous nodules, and draining tophi in right second finger, was treated by free flap and finally got the more functional and aesthetic result. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1321-x
更新日期：2010-03-01 00:00:00
abstract：:Over the last decade, biologic therapeutic proteins have advanced the treatment of diseases such as rheumatoid arthritis (RA). Therapeutic antibodies such as infliximab, adalimumab, rituximab, tocilizumab, golimumab, certolizumab pegol, the receptor construct etanercept, and abatacept, an anticluster of differentiatio...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-012-2040-2
更新日期：2012-09-01 00:00:00
abstract：:Fibromyalgia is characterized by widespread pain, sleep problems, fatigue, functional impairment, psychological distress, and cognitive dysfunction. The objective of this meta-analysis is to synthesize the available data on the effectiveness of pharmacological and non-pharmacological interventions across all domains i...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-015-3144-2
更新日期：2016-03-01 00:00:00
abstract：:The aim of this blinded, randomised, multicentre study was to compare the tolerability of aspirin, paracetamol and ibuprofen in common pain resulting from musculoskeletal conditions (MSC) in general practice with patients with other non-MSC pain conditions. Patients took aspirin, paracetamol (both up to 3g daily) or i...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s100670200007
更新日期：2002-02-01 00:00:00
abstract：:The aims of this study were to characterize a minimally invasive technique of minor salivary gland biopsy of the lower lip and to present a large patient material undergoing this procedure because of a suspicion of Sjögren's syndrome (SS), as well as to assess the procedure's short-term and long-term value as a diagno...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0457-1
更新日期：2007-07-01 00:00:00
abstract：:Until recently, renal crisis was the most significant cause of morbidity and mortality in patients with scleroderma (SSc). Nowadays, following the introduction of angiotensin-converting enzyme inhibitors used in renovascular hypertension, pulmonary fibrosis and pulmonary hypertension have become the most common causes...
journal_title：Clinical rheumatology
pub_type： 临床试验,杂志文章
doi：10.1007/s100670050138
更新日期：1999-01-01 00:00:00
abstract：:Forty-four patients with typical palindromic rheumatism were typed for HLA-A,B,C and DR antigens. The mean duration of follow-up of our patients was 4.0 yrs. (range 1-12 yrs.). During this time 27% of patients showed a seropositivity; 22% of patients developed polyarthritis, 1 patient revealed a Sjögren syndrome and 3...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:In a Sidonian sarcophagus, from the Late Antique/early Christian period, skeletal remains of two persons were found. One of them, male, 30-50 years old, was found almost completely ankylosed, with highly osteoporotic bones and prominent erosion of joint surfaces. We diagnosed rheumatoid arthritis based on the eroded o...
journal_title：Clinical rheumatology
pub_type： 历史文章,杂志文章
doi：10.1007/s10067-016-3493-5
更新日期：2017-01-01 00:00:00
abstract：:The idiopathic inflammatory myopathies (IIM) constitute a subset of autoimmune conditions primarily affecting muscle, along with many extra-muscular manifestations. Proximal muscle weakness is the dominant symptom in the IIM. In addition, many patients will have cutaneous manifestations, pulmonary manifestations, and ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-2891-4
更新日期：2015-05-01 00:00:00
abstract：:Disease-modifying antirheumatic biological and non-biological therapies are associated with reduced disease progression and joint destruction. Suggestions have been made that total knee and hip joint arthroplasty indications are decreasing as a beneficial effect of the new forms of therapy for rheumatoid arthritis. We...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1629-6
更新日期：2011-04-01 00:00:00
abstract：:Juvenile systemic lupus erythematosus (JSLE) is a multi-system autoimmune inflammatory disease. Generally, 60% of patients will develop lupus nephritis (LN); thus, early recognition and treatment is associated with better outcome. Interleukin 22 (IL-22) is involved in tissue inflammation and is regulated by interleuki...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3812-5
更新日期：2018-02-01 00:00:00
abstract：:This study shows that N-acetyl-galactosamine and N-acetyl-glucosamine can diminish the production of superoxide anion from cytochalasin-B treated PMNs stimulated with FMLP. Inhibition ranged from 80.9% to 1.8%. N-acetyl-galactosamine was superior to N-acetyl-glucosamine, but both showed their action in a dose-related ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02207968
更新日期：1992-06-01 00:00:00
abstract：:Septic sacroiliitis in childhood is a relatively rare condition. We describe a case of septic sacroiliitis occurring in an 11-year-old girl in whom the diagnosis was suspected on clinical findings and bone scan. Immunoscintigraphy with 99mTc-labelled antigranulocyte antibodies further supported the hypothesis for a se...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02231689
更新日期：1996-01-01 00:00:00
abstract：:Sixty-one Thai patients with ankylosing spondylitis (AS), diagnosed in accordance with Rome and New York criteria for AS, were studied. The cases includes idiopathic AS (46 cases), Reiter's syndrome AS (8 cases) and psoriatic spondylitis (7 cases). The vast majority of patients were male (Male:Female = 11.2:1), and in...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02032322
更新日期：1985-03-01 00:00:00
