Abstract:
:This study shows that N-acetyl-galactosamine and N-acetyl-glucosamine can diminish the production of superoxide anion from cytochalasin-B treated PMNs stimulated with FMLP. Inhibition ranged from 80.9% to 1.8%. N-acetyl-galactosamine was superior to N-acetyl-glucosamine, but both showed their action in a dose-related fashion. The mannosamine may diminish the superoxide production, but without a statistical significance. Other sugars such as L-fucose, D-fucose and D-glucose failed to induce inhibition of superoxide generation. Previous reports showed that sugars interfere with carbohydrates lectins interaction. This study shows that aminosugars can do more than interfere with carbohydrates-lectin interaction. The mechanism is not completely known yet. The question whether aminosugars affect cell-cell interaction, regulation of respiratory burst, inflammatory mediators functions, or the glucose uptake and utilization needs further study.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Kamel M,Alnahdi Mdoi
10.1007/BF02207968subject
Has Abstractpub_date
1992-06-01 00:00:00pages
254-60issue
2eissn
0770-3198issn
1434-9949journal_volume
11pub_type
杂志文章abstract::The aim of this study was to investigate the involvement of autonomic nervous system (ANS) function by using power spectral analysis of heart rate variability (HRV) method in patients with ankylosing spondylitis (AS). The study included 94 AS patients all fulfilling the New York criteria for AS, and 49 healthy volunte...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/pl00011198
更新日期:2001-01-01 00:00:00
abstract::We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-005-0031-2
更新日期:2006-07-01 00:00:00
abstract::Adiponectin is a hormone released by adipose tissue with antidiabetic, antiatherogenic, and anti-inflammatory properties. The present observational study focused on the relation between serum adiponectin level and the disease severity of established rheumatoid arthritis (RA). Ninety patients with more than 5-year diag...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-1074-y
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:Patients with axial spondyloarthritis (SpA) are subjected to elevated cardiovascular risks, but assessment of early myocardial damage and clinical risk stratification remained obscure. The aim of this study was to evaluate the prognostic value of speckle-tracking strain analysis and serum high-sensitivity tro...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-020-05112-5
更新日期:2020-11-01 00:00:00
abstract::The authors report the case of a 54-year-old man suffering from steroid-induced osteoporosis, who presented with severe oral ulcerations due to sucking alendronate tablets instead of swallowing them. The misuse of alendronate in this case, underlies the risk of direct mucosal injury with this drug. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670050116
更新日期:1999-01-01 00:00:00
abstract::A 12-week double-blind randomized drug trial followed by an open extension period of 36 weeks was carried out in 38 male patients with ankylosing spondylitis (AS) to compare the efficacy and safety of diflunisal (500 mg twice daily) and phenylbutazone (200 mg twice daily). Both drugs proved to be effective in improvin...
journal_title:Clinical rheumatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02032359
更新日期:1986-06-01 00:00:00
abstract::Either total hip arthroplasty (THA), total knee arthroplasty (TKA) or both were performed in 105 patients from 1981 to 1994. These patients were experiencing severe joint destruction in the lower extremities due to rheumatoid arthritis (RA). These patients were followed for more than 2 years after their last operation...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF01452259
更新日期:1998-01-01 00:00:00
abstract::The American College of Rheumatology (ACR) classification criteria for lupus and Systemic Lupus International Collaborating Clinics (SLICC) criteria are designed to classify disease. However, they have become widely used as diagnostic criteria in clinical situations. Patients may be labelled as systemic lupus erythema...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-3999-0
更新日期:2018-03-01 00:00:00
abstract::Innate immunity has been widely accepted as one of the major cause for the alteration of immune system and progression of autoimmune diseases. Natural killer (NK) cells and natural killer T (NKT) cells have not been explored in clinical studies for their cytolytic components in association with rheumatoid arthritis (R...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-014-2641-z
更新日期:2014-08-01 00:00:00
abstract::Children with juvenile idiopathic arthritis (JIA) may infrequently present with localized anterior knee pain or swelling, in addition to generalize knee pain induced by JIA. We report five cases of deep infrapatellar bursitis in children with JIA. The clinical features, radiological findings, management, and outcome o...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1620-2
更新日期:2011-02-01 00:00:00
abstract::Neurological involvement is uncommon in systemic sclerosis. Most of the reported cases concern trigeminal neuropathy or peripheral nerve entrapment. We report a third case of brachial plexopathy, presumably related to vasculitis, in a patient with systemic sclerosis, which improved after cyclophosphamide therapy. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s100670200106
更新日期:2002-09-01 00:00:00
abstract::We describe four cases of giant cell arteritis (GCA) that presented with occipital headache in the last 6 months. Typical ultrasound features of GCA were found in the occipital arteries which helped to confirm the diagnosis. One patient had already suffered significant visual loss by the time the diagnosis was made, r...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-017-3946-5
更新日期:2018-02-01 00:00:00
abstract::Articular involvement is described in a 58-year-old female patient with scleroderma. Radiological findings included intra-articular calcification, destructive osteoarthritis and selective involvement of the first metacarpal base. The discussion attempts to explain the way in which intra-articular calcification and ost...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02032338
更新日期:1984-09-01 00:00:00
abstract::The swift and accurate diagnosis of acute arterial occlusion and limb ischemia is critical to prevent morbidity from this vascular emergency as reported by Bettman et al. (Radiology 215:101-105, 2000). There are a number of imaging modalities available to the diagnosing physician. However, the most appropriate modalit...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1419-1
更新日期:2013-03-01 00:00:00
abstract::The original published version of this article contained the incorrect Table 2 and are now presented correctly in this article. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10067-020-04926-7
更新日期:2020-04-01 00:00:00
abstract::Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3932-y
更新日期:2018-04-01 00:00:00
abstract::The burden of anxiety in patients with systemic lupus erythematosus (SLE) compared to those with other inflammatory rheumatological conditions is unclear. We aimed to compare the frequency and level of anxiety between patients with SLE, rheumatoid arthritis (RA), and gout and healthy individuals and explore independen...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-010-1651-8
更新日期:2011-06-01 00:00:00
abstract::A 45-year-old patient is described presenting with severe axial osteoporosis. The presence of maculopapular skin lesions and the combination of osteolytic and osteoblastic bone lesions led to the tentative diagnosis of systemic mastocytosis. This diagnosis was confirmed by measurement of urinary histamine metabolites ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02206850
更新日期:1987-09-01 00:00:00
abstract::Antiglomerular basement membrane antibody disease (aGD) remains a very uncommon entity in the pediatric population, characterized by pulmonary hemorrhage, glomerulonephritis, and antibodies against the glomerular basement membrane. We herein describe the case of a 14-year-old girl with primary pulmonary symptoms diagn...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-012-2062-9
更新日期:2012-12-01 00:00:00
abstract::Type B insulin resistance syndrome is characterized by the formation of autoantibodies against insulin receptors, which can cause severe hyperglycemia and insulin resistance. Systemic lupus erythematosus is the most common underlying diseases of the syndrome. This report details our study of a case involving a Chinese...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-012-2098-x
更新日期:2013-02-01 00:00:00
abstract::The pharmacokinetic profile of a single 10 mg oral dose of prednisolone was studied in three groups of six patients with rheumatoid arthritis (RA), polymyalgia rheumatica (PMR) and bronchial asthma (BA) who were already receiving steroid therapy. A fourth group of age and sex-matched normal controls was also studied. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/BF02054250
更新日期:1986-09-01 00:00:00
abstract::The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration < 2 years) with forced vit...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-018-4266-0
更新日期:2018-11-01 00:00:00
abstract::The objective of this study is to determine whether meniscal extrusion (ME) of the medial meniscus on ultrasonography affects knee osteoarthritis (KOA) progression during 3-year follow-up. Two hundred seventy volunteers (70 men, 200 women; mean age 60.5 years) participated. Weight-bearing radiographs were evaluated. A...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-017-3803-6
更新日期:2017-11-01 00:00:00
abstract::In this scoping review, we sought to summarize the types of outcomes collected in pregnant patients with ankylosing spondylitis (AS), and to identify some methodological limitations related to pregnancy research in these patients. A comprehensive search was done to identify relevant articles in MEDLINE and Embase. We ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-021-05588-9
更新日期:2021-01-19 00:00:00
abstract::Efficacy of hip protector pads to prevent hip fracture is controversial. This study was done to evaluate two comparable groups for fracture risk. Two matched cohorts of long-term care residents in Canada, assessing the efficacy of hip protector pads. Evaluation included demographics, medications/diagnoses, cognition (...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1115-1
更新日期:2009-06-01 00:00:00
abstract::The presentation of the Table 1 of the original version of this article was incorrectly published. The Table is now presented correctly in this article. ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s10067-018-4098-y
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:Tumor necrosis factor inhibitors (anti-TNF) have become the standard treatment for rheumatoid arthritis (RA). However, evidence is inconsistent as to whether RA patients with anti-TNF are associated with an increased risk of non-melanoma skin cancer (NMSC) compared with those without anti-TNF. We performed a ...
journal_title:Clinical rheumatology
pub_type: 杂志文章,meta分析
doi:10.1007/s10067-019-04865-y
更新日期:2020-03-01 00:00:00
abstract::The objectives of the study were to assess sleep disturbances in systemic lupus erythematosus (SLE) and to compare these with a working sample and a treatment-seeking sample reporting insomnia. The primary sample was 172 people with SLE. This sample represented 32% of all members of two lupus support association. Two ...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-008-0884-2
更新日期:2008-09-01 00:00:00
abstract::Renal involvement in systemic lupus erythematosus (SLE) is common and has been associated with an increased risk of mortality [1]. Early diagnosis is imperative to control proteinuria and prevent the progression to end-stage renal disease. Standard induction therapies include cyclophosphamide (CYC) and mycophenolate m...
journal_title:Clinical rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10067-016-3511-7
更新日期:2017-03-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) has rarely being reported among African Blacks, in contrast with African-Americans. Such reports have been mostly case reports. Our encounter with new cases shows that this disease may not be rare after all. The objective of this study was to study the clinical presentations, laborat...
journal_title:Clinical rheumatology
pub_type: 杂志文章
doi:10.1007/s10067-009-1139-6
更新日期:2009-06-01 00:00:00