Prednisolone pharmacokinetics in patients with rheumatoid arthritis, polymyalgia rheumatica and asthma.

abstract：OBJECTIVE:Anti-cyclic citrullinated peptide 2 antibodies (anti-CCP2) and rheumatoid factor (RF) in rheumatoid arthritis (RA) has been extensively assessed in industrialized countries. We investigated the diagnostic and prognostic impact of anti-CCP2 and RF isotypes in a Sudanese cross-sectional RA cohort. METHODS:Cons...

journal_title：Clinical rheumatology

authors： Elshafie AI,Elbagir S,Aledrissy MIE,Elagib EM,Nur MAM,Rönnelid J

更新日期：2019-06-01 00:00:00

abstract：:Eighty patients with Reiter's syndrome (RS) were studied retrospectively. A comparison was made between patients with the complete syndrome and patients with the incomplete syndrome. A comparison was also made between patients with and without HLA-B27. There were no major differences in severity and duration of the ar...

journal_title：Clinical rheumatology

authors： Bengtsson A,Lindström FD,Lindblom B

更新日期：1986-01-01 00:00:00

abstract：:To describe clinical and epidemiological data of Behçet's disease (BD) in Brazil, we retrospectively reviewed records of all patients seen between 2006 and 2007 at the BD outpatient clinic of University of Sao Paulo. One hundred and six patients fulfilled the International Study Group for Behçet's Disease diagnostic c...

journal_title：Clinical rheumatology

authors： Neves FS,Caldas CA,Lage LV,Goldenstein-Schainberg C,Gonçalves CR

更新日期：2009-05-01 00:00:00

abstract：:This study shows that N-acetyl-galactosamine and N-acetyl-glucosamine can diminish the production of superoxide anion from cytochalasin-B treated PMNs stimulated with FMLP. Inhibition ranged from 80.9% to 1.8%. N-acetyl-galactosamine was superior to N-acetyl-glucosamine, but both showed their action in a dose-related ...

journal_title：Clinical rheumatology

authors： Kamel M,Alnahdi M

更新日期：1992-06-01 00:00:00

abstract：:The effect of niflumic acid on hyaluronic acid and proteoglycan metabolism of human cartilage cells was investigated in vitro. Cartilage cells were obtained from five different donors. Niflumic acid levels used in the test systems ranged from 0 to 22 microgramsr/ml and were comparable to serum concentrations in humans...

journal_title：Clinical rheumatology

authors： Verbruggen G,Veys EM,Malfait AM,Schatteman L,Wieme N,Nimmegeers J,Gerin MG,Broddelez C

更新日期：1990-03-01 00:00:00

abstract：:Joint lavage for knee osteoarthritis is an invasive procedure that can be stressful and painful. We aimed to assess the impact of music therapy on perioperative anxiety, pain and tolerability of the procedure in patients undergoing joint lavage performed with two needles. We randomized all patients diagnosed with knee...

journal_title：Clinical rheumatology

authors： Ottaviani S,Bernard JL,Bardin T,Richette P

更新日期：2012-03-01 00:00:00

abstract：:This study aimed to compare the diagnostic value of ultrasonography to conventional radiography in detecting osteophytes and erosions in the midfoot joints in patients suffering from inflammatory and non-inflammatory joint disease. Patients with current foot radiographs were included and stratified in two cohorts: inf...

journal_title：Clinical rheumatology

authors： Camerer M,Ehrenstein B,Hoffstetter P,Fleck M,Hartung W

更新日期：2017-09-01 00:00:00

abstract：:The aim of this study was to assess the role of oxidative stress in the pathogenesis of Henoch-Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase (ARYL), and paraoxonase (PON) as antioxidant enzymes and serum malondialdehyde (MDA) level as an indicator of lipid peroxidation, together wi...

journal_title：Clinical rheumatology

authors： Ece A,Kelekçi S,Kocamaz H,Hekimoğlu A,Balik H,Yolbaş I,Erel O

更新日期：2008-02-01 00:00:00

abstract：:We compared the short-term effects of Stanger bath therapy and conventional exercises on spinal mobility, functional capacity, disease activity, and quality of life with conventional exercise alone in ankylosing spondylitis (AS) patients. A total of 58 patients with a diagnosis of AS according to the modified New York...

journal_title：Clinical rheumatology

authors： Gurcay E,Yuzer S,Eksioglu E,Bal A,Cakci A

更新日期：2008-07-01 00:00:00

abstract：:This study aims to examine the needs and preferences regarding the delivery of health care services and information provision and their determinants in patients with systemic sclerosis (SSc). A questionnaire was sent to 77 SSc outpatients, comprising 27 items on health care needs within the domains physical, psycholog...

journal_title：Clinical rheumatology

authors： Schouffoer AA,Zirkzee EJ,Henquet SM,Caljouw MA,Steup-Beekman GM,van Laar JM,Vlieland TP

更新日期：2011-06-01 00:00:00

abstract：:The Revised Fibromyalgia Impact Questionnaire (FIQR) attempts to address the limitations of the Fibromyalgia Impact Questionnaire (FIQ). As there is no Turkish version of the FIQR available, we aimed to investigate the validity and reliability of a Turkish translation of the FIQR in Turkish female fibromyalgia (FM) pa...

journal_title：Clinical rheumatology

authors： Ediz L,Hiz O,Toprak M,Tekeoglu I,Ercan S

更新日期：2011-03-01 00:00:00

abstract：:The aim of this study is to assess the gender differences in spondyloarthritides (SpAs) in terms of disease onset, clinical presentation, and the Bath Ankylosing Spondylitis Disease Activity and Functional indices (BASDAI and BASFI). We analysed data from a predominantly female cohort. Five hundred and 16 patients (ma...

journal_title：Clinical rheumatology

authors： Roussou E,Sultana S

更新日期：2011-01-01 00:00:00

abstract：:The investigation concerned changes in vitamin A derivatives (retinol and retinyl) content in serum of patients suffering from two types of rheumatic diseases--rheumatoid arthritis (RA) and osteoarthrosis. Healthy women of similar age served as control. It was found that the retinol content of the serum in the group s...

journal_title：Clinical rheumatology

authors： Mezes M,Bartosiewicz B

更新日期：1982-09-01 00:00:00

abstract：:Behçet's disease (BD) related amyloidosis is relatively rare. Serum amyloid A protein (SAA) protein gene polymorphism is one of the factors implicated in the pathogenesis of AA type amyloidosis. The aim of this study is to investigate SAA1 gene polymorphism in different patient groups: (1) BD related amyloidosis, (2) ...

journal_title：Clinical rheumatology

authors： Utku U,Dilek M,Akpolat I,Bedir A,Akpolat T

更新日期：2007-06-01 00:00:00

abstract：:The objectives of this study are to assess the risk of asymptomatic cranial neuropathy among patients with systemic lupus erythematosus (SLE) and find any association with disease activity and antiribosomal P antibodies. This study is a case-control study including 60 female patients and 30 healthy female controls. Di...

journal_title：Clinical rheumatology

authors： Gaber W,Ezzat Y,El Fayoumy NM,Helmy H,Mohey AM

更新日期：2014-01-01 00:00:00

abstract：:To investigate the value of lone anti-Smith antibody (anti-Sm) using Euroimmun line immunoassay (LIA) in a Chinese population. One thousand two hundred eight of 39,766 patients who were analyzed for anti-Sm had positive anti-Sm, and were divided into true group (having both positive Sm and nRNP/Sm bands) and lone grou...

journal_title：Clinical rheumatology

authors： Meng Y,Deng S,Huang Z,Hu J,Zhang J,Xu D,Qin S,Tan C,Wu Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Clustering of autoimmune diseases is common and may be due to genetic background and exposition to environmental triggers. OBJECTIVE:The aim is to carry out a laboratory and clinical study of the prevalence of gastrointestinal organ-specific autoantibodies in rheumatoid arthritis (RA) patients and their rel...

journal_title：Clinical rheumatology

authors： Goeldner I,Skare TL,de Messias Reason IT,Nisihara RM,Silva MB,da Rosa Utiyama SR

更新日期：2011-01-01 00:00:00

abstract：:To estimate the mortality and describe the causes of death in a large multicenter cohort of hospitalized patients with SLE in China. This was a retrospective study of a nationwide SLE cohort (10 centers, 29,510 hospitalized patients) from 2005 to 2014 in China. Standardized mortality ratios (SMRs) were calculated for ...

journal_title：Clinical rheumatology

authors： Wu XY,Yang M,Xie YS,Xiao WG,Lin J,Zhou B,Guan X,Luo CN,Che N,Liu XZ,Wang C,Teng JL,Cheng XB,Ye JN,Su YT,Shi H,Yin YF,Liu MR,Sun Y,Hu QY,Zhou ZC,Chi HH,Liu Y,Zhang X,Chen JW,Zhang MJ,Zhao DB,Yang CD,

更新日期：2019-01-01 00:00:00

abstract：:The aim of this study was to describe the abnormalities identified with conventional MRI in children with neuropsychiatric systemic lupus erythematosus (NPSLE). This was single-centre (Great Ormond Street Hospital, London) retrospective case series of patients with juvenile NPSLE seen in 2003-2013. Brain MR images of ...

journal_title：Clinical rheumatology

authors： Al-Obaidi M,Saunders D,Brown S,Ramsden L,Martin N,Moraitis E,Pilkington CA,Brogan PA,Eleftheriou D

更新日期：2016-10-01 00:00:00

abstract：:We aimed to investigate the possible effects of thioredoxin 1 (Trx1) on the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) and elucidate the possible mechanisms involved. We investigated the distribution and expression of Trx1 in synovial tissues from RA and osteoarthritis (...

journal_title：Clinical rheumatology

authors： Lu T,Zong M,Fan S,Lu Y,Yu S,Fan L

更新日期：2018-01-01 00:00:00

abstract：:The burden of anxiety in patients with systemic lupus erythematosus (SLE) compared to those with other inflammatory rheumatological conditions is unclear. We aimed to compare the frequency and level of anxiety between patients with SLE, rheumatoid arthritis (RA), and gout and healthy individuals and explore independen...

journal_title：Clinical rheumatology

authors： Mak A,Tang CS,Chan MF,Cheak AA,Ho RC

更新日期：2011-06-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects various organs and systems. Increased apoptosis, together with defects in the uptake of apoptotic bodies, are thought to have a pathogenic role in SLE. By detection of chromatin condensation, 30% of apoptosis was detected in peripheral bl...

journal_title：Clinical rheumatology

authors： Pitidhammabhorn D,Kantachuvesiri S,Totemchokchyakarn K,Kitiyanant Y,Ubol S

更新日期：2006-09-01 00:00:00

abstract：:Primary knee osteoarthritis (OA) contributes to disability among middle-aged and elderly people. Dickkopf-1 (Dkk-1) and sclerostin are inhibitors of Wnt/β-catenin signaling pathway implicated in regulation of cartilage homeostasis and bone formation, respectively. We aim to investigate the association between the seru...

journal_title：Clinical rheumatology

authors： Theologis T,Efstathopoulos N,Nikolaou V,Charikopoulos I,Papapavlos I,Kokkoris P,Papatheodorou A,Nasiri-Ansari N,Kassi E

更新日期：2017-08-01 00:00:00

abstract：:Hypercalcaemia is a common electrolyte abnormality. The vast majority of patients will be shown to have either hyperparathyroidism or malignancy. In less than 10% of patients other, less common causes of hypercalcaemia will be present. Systemic lupus erythematosus is a very rare cause of hypercalcaemia. It may be asso...

journal_title：Clinical rheumatology

authors： Berar-Yanay N,Weiner P,Magadle R

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:This study was conducted to assess the safety and efficacy of intra-articular injection of etanercept and compare it with corticosteroid injection in rheumatoid arthritis (RA) patients. METHODS:Fifty patients with RA who suffered from activity in one joint were randomized into two groups, received an intra-...

journal_title：Clinical rheumatology

authors： Salem RM,El-Deeb AE,Elsergany M,Elsaadany H,El-Khouly R

更新日期：2021-02-01 00:00:00

abstract：:It has recently been claimed that some of the symptoms in patients with Behçet's disease (BD) can be activated after the patient has stopped smoking. In this study we investigated the effect of smoking on the symptoms of Behçet's disease. Fifty asymptomatic current smokers (CS) who promised to stop smoking (group 1) a...

journal_title：Clinical rheumatology

authors： Soy M,Erken E,Konca K,Ozbek S

更新日期：2000-01-01 00:00:00

abstract：:The objective of this study is to identify the clinical differences between infectious meningitis and neuropsychiatric systemic lupus erythematosus (NPSLE) in patients with SLE. Clinical manifestations, laboratory test results, and prognoses of 14 SLE patients complicated with various infectious meningitis, hospitaliz...

journal_title：Clinical rheumatology

authors： Chen J,Feng X,Wang H,Hua B,Ding C,Liu B,Sun L

更新日期：2015-02-01 00:00:00

abstract：:Gold salts in vitro modulate lymphocyte proliferation to mitogens and antigens and macrophage phagocytosis. These effects are not confined to gold salts; D-penicillamine and chloroquine as well as some of the non-steroidal anti-inflammatory drugs (NSAIDs) have in vivo immunoregulatory effects. Peripheral blood mononuc...

journal_title：Clinical rheumatology

authors： Coughlan RJ,Richter MB,Panayi GS

更新日期：1984-03-01 00:00:00

abstract：:Subcutaneous nodules are the most common conspicuous extra-articular manifestation of rheumatoid arthritis (RA). Cardiovascular disease (CVD) is the leading cause of death in patients with RA. The objective of this study is to examine the possibility of a relationship between subcutaneous nodules and "first ever" card...

journal_title：Clinical rheumatology

authors： Kaushik P,Solomon DH,Greenberg JD,Anderson JT,Reed G,Pala O,Sumbul-Yuksel B,Kadam P,Kremer JM,CORRONA investigators.

更新日期：2015-10-01 00:00:00

abstract：:To explore whether femoral cartilage thickness is related (and changes) with muscle strength in subjects with knee osteoarthritis (OA). Forty patients (27 F, 13 M) with knee OA-who were under quadriceps muscle strengthening program-were enrolled in the study. Isokinetic/isometric knee muscle strength measurements (at ...

journal_title：Clinical rheumatology

authors： Tuna S,Balcı N,Özçakar L

更新日期：2016-08-01 00:00:00