Abstract：
:To explore whether femoral cartilage thickness is related (and changes) with muscle strength in subjects with knee osteoarthritis (OA). Forty patients (27 F, 13 M) with knee OA-who were under quadriceps muscle strengthening program-were enrolled in the study. Isokinetic/isometric knee muscle strength measurements (at 30-60° angles and 60-180° velocity) were performed at baseline, end of the muscle strengthening program, and third month control visit using a biodex dynamometer. Femoral cartilage thicknesses (at medial/lateral condyle and intercondylar area) were measured using ultrasonography. Seventy-nine knees of 40 patients (27 F, 13 M) aged 52.03 ± 11.72 years (range, 26-71) were analyzed. Mean VAS scores on the first and third months were significantly lower than the initial values (p < 0.001, p = 0.049). Isometric peak torque and total work values at 180 °/s were significantly higher than the baseline measurements at first and third month controls (all p < 0.05). Cartilage thicknesses (at three sites) were significantly higher than the baseline measurements (all p < 0.05) on the third month but not on the first month (all p > 0.05). Femoral cartilage thicknesses were positively correlated with isometric strength values at baseline and third month. We propose that femoral cartilage thicknesses increase on the third month of strengthening therapy. Since this late-phase thickening parallels the earlier increase in muscle strength (starting, on the first month), we speculate that regeneration rather than edema might be the primary underlying cause.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Tuna S,Balcı N,Özçakar Ldoi
10.1007/s10067-016-3271-4subject
Has Abstractpub_date
2016-08-01 00:00:00pages
2073-2077issue
8eissn
0770-3198issn
1434-9949pii
10.1007/s10067-016-3271-4journal_volume
35pub_type
杂志文章abstract：:The purpose of this report is to describe the overall safety profile of both short- and longer-term duloxetine treatment of fibromyalgia. Data from four double-blind, randomized, placebo-controlled studies (two with 6-month open-label extension phases) and a 1-year, open-label safety study were included. Safety measur...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-009-1203-2
更新日期：2009-09-01 00:00:00
abstract：:Intravenous immunoglobulin (IVIg) is currently used with much enthusiasm for the treatment of many autoimmune diseases, including systemic lupus erythematosus (SLE). Among its various indications, IVIg has also been found to be beneficial in myocarditis, whether or not it is associated with an autoimmune disease (e.g....
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670050091
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:The association between hyperuricemia and insulin resistance (IR) has been demonstrated by many studies, but the traditional IR indexes are too impractical to be used in clinical practice for the recognition of the IR state in individuals with hyperuricemia. Therefore, we aimed to further investigate the asso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04671-6
更新日期：2019-11-01 00:00:00
abstract：:Functional limitation is often complained by patients with ankylosing spondylitis (AS). With a rising number of patients suffering from AS, there are a limited number of reports focusing on functional limitation of AS in Chinese patients. This study was conducted to investigate the level of functional limitation and e...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3563-3
更新日期：2017-04-01 00:00:00
abstract：:The effect of the immunostimulant C. parvum on the establishment and course of mycoplasma arthritis of mice was investigated. Male Swiss albino mice were injected intra-venously with M. arthritidis culture and intraperitoneally with C. parvum. It was shown that mice immunostimulated with C. parvum were significantly p...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02032174
更新日期：1983-06-01 00:00:00
abstract：:We described a 21-year-old woman with a diagnosis of Sjögren syndrome that came for consultation with a localized mass over her left arm of fast growth. Lab results were normal; a Doppler ultrasound showed the presence of partial thrombosis in the left axillary vein; a magnetic resonance imaging showed edema on the bi...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-015-3133-5
更新日期：2016-04-01 00:00:00
abstract：:There is an increasing concern over generalizability of trial results. We investigated eligibility criteria of knee osteoarthritis clinical trials. Eligible trials were randomized, placebo-controlled trials that were identified by searches in MEDLINE, SCOPUS, and the Cochrane Central Register of Controlled Trials. We ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-013-2342-z
更新日期：2013-11-01 00:00:00
abstract：:Although peripheral blood eosinophilia is observed in patients with active inflammatory rheumatoid arthritis (RA), RA is not a recognised cause of pulmonary eosinophilia. We describe a 55-year-old woman affected by chronic eosinophilic pneumonia (CEP) concomitantly with an initiation of RA. Both diseases responded rap...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-003-0703-8
更新日期：2003-09-01 00:00:00
abstract：:The objective of the study is to determine the risk factors for the development of reactive arthritis (ReA) and examine the factors associated with the persistence of symptoms. Patients with a new diagnosis of ReA and controls with a gastrointestinal (GI), urogenital, or sexually transmitted infection in the 3-6 month...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3911-3
更新日期：2018-02-01 00:00:00
abstract：:Hypercalcaemia is a common electrolyte abnormality. The vast majority of patients will be shown to have either hyperparathyroidism or malignancy. In less than 10% of patients other, less common causes of hypercalcaemia will be present. Systemic lupus erythematosus is a very rare cause of hypercalcaemia. It may be asso...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s100670170088
更新日期：2001-01-01 00:00:00
abstract：:Physical therapy and exercise (recreational activity) are the cornerstones of non-pharmacologic therapy in axial spondyloarthritis (AxSpA) [1, 2]. These are components of physical activity, though physical activity is made up of activities beyond these and also include occupational activity. Not all activities in AxSp...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-016-3264-3
更新日期：2016-06-01 00:00:00
abstract：:The goals of this study were to determine if secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis (RA) compared to control subjects and to examine the relationships of S-SMase activity with functional status, quality of life, and RA disease activity measurements. We collected...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3824-1
更新日期：2018-05-01 00:00:00
abstract：:The above article originally published with an error present in Table 2 and is now presented correctly in this article. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10067-018-4280-2
更新日期：2018-10-01 00:00:00
abstract：:Recently, the Ankylosing Spondylitis Disease Activity Score (ASDAS), a new index, has been shown to be validated and highly discriminatory in assessing ankylosing spondylitis (AS) disease activity. This study is to evaluate the performance of ASDAS in a local Chinese cohort of AS in a cross-sectional setting and to co...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2729-5
更新日期：2014-08-01 00:00:00
abstract：:We report a case of a 53-year-old woman diagnosed of systemic sclerosis. She underwent an episode of pulmonary haemorrhage, characterized by haemoptysis, sudden anaemization, and bilateral alveolar infiltration during her hospitalization, which was resolved with steroid treatment. Subsequently, she developed a focal n...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/BF02207098
更新日期：1992-03-01 00:00:00
abstract：:The aim of this study was to evaluate the long-term efficacy and safety of single or 1-3 weekly injections of hylan G-F 20 at 1 year following the first injection for knee osteoarthritis (OA). Searches were conducted in PubMed/MEDLINE, Embase, and CENTRAL and included relevant conference proceedings (January 1, 1995-A...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-020-05477-7
更新日期：2020-10-27 00:00:00
abstract：:We describe two cases of rheumatoid arthritis (RA) patients and concomitant hepatitis C virus infection (HCV), treated with cyclosporine A (CsA) and anti-TNF-alpha agents. SGOT/SGPT and HCV-RNA serum levels remained unchanged longer than 1 year of treatment. No side effects were registered. We suggest that combination...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0412-1
更新日期：2007-07-01 00:00:00
abstract：:The levels of 63 cytokines, chemokines, and growth factors were measured in the serum of four patients with idiopathic morphea and of one patient with vitamin K1-induced morphea employing a multiplex assay to identify the role of inflammatory/immunologic events in their pathogenesis. Full-thickness skin biopsies of af...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3580-2
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVES:The invalidation or social pain is an important but neglected issue in polysymptomatology of fibromyalgia (FM). This study sought whether tracing-perceived invalidation could be effective to discriminate between the presence and absence of FM in chronic pain patients with respect to five different sources, i...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05515-4
更新日期：2021-01-07 00:00:00
abstract：:2'5'-Oligoadenylate synthetase (OAS) was shown to be related to systemic lupus erythematosus (SLE) 20 years ago, and was rediscovered to be involved in type I interferon pathway in SLE by several microarray gene expression studies recently. The goal of this study was to investigate OAS isoform expressions in lupus pat...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0260-z
更新日期：2007-02-01 00:00:00
abstract：:Fibromyalgia is characterized by widespread pain, sleep problems, fatigue, functional impairment, psychological distress, and cognitive dysfunction. The objective of this meta-analysis is to synthesize the available data on the effectiveness of pharmacological and non-pharmacological interventions across all domains i...
journal_title：Clinical rheumatology
pub_type： 杂志文章,meta分析
doi：10.1007/s10067-015-3144-2
更新日期：2016-03-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects various organs and systems. Increased apoptosis, together with defects in the uptake of apoptotic bodies, are thought to have a pathogenic role in SLE. By detection of chromatin condensation, 30% of apoptosis was detected in peripheral bl...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-0162-5
更新日期：2006-09-01 00:00:00
abstract：:Since diffuse idiopathic skeletal hyperostosis (DISH) is frequently difficult to differentiate radiologically from the axial involvement of ankylosing spondylitis and osteoarthrosis, some features of these 3 different diseases were compared. The predominantly horizontal nature of the enthesiophyte in DISH and its righ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02283118
更新日期：1992-12-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is a multi-system chronic inflammatory disease with a broad spectrum of clinical and serological manifestations. Although clinical evidence of proximal skeletal muscle involvement is not rare in patients with SLE, there is no knowledge about the effects of SLE on the macroscopic stru...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-013-2249-8
更新日期：2013-08-01 00:00:00
abstract：:We investigated the rate of rheumatoid factor (RF) false positivity at diagnosis and its influence on clinical and prognostic features and rheumatoid arthritis (RA) development during the follow-up in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients without RA or other medical conditions...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3902-4
更新日期：2018-10-01 00:00:00
abstract：:Intercellular adhesion molecule-1 (ICAM-1) is a membrane bound molecule that plays an important role in the pathogenic inflammatory responses observed in vasculitis. The aim of this study was to determine whether levels of soluble ICAM-1 sICAM-1) shedding into the circulation reflect the vascular injury found in nailf...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02230359
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:We aimed to evaluate the effect on renal functions and blood pressure of the addition of low dose aspirin (LDA) to cyclooxygenase-2 (COX-2) inhibitors or nonselective NSAIDs. METHODS:Two groups each containing 14 patients with one group using celecoxib and the other indomethacin regularly for at least 1 week...
journal_title：Clinical rheumatology
pub_type： 临床试验,信件
doi：10.1007/s10067-005-1167-9
更新日期：2006-02-01 00:00:00
abstract：:Ankylosing spondylitis (AS) is associated with an increased risk of atherosclerotic cardiovascular disease (ACD). The atherogenic index of plasma (AIP), which is the logarithmic transformation of the plasma triglyceride (TG) level to the high-density lipoprotein level (HDL) ratio, has been suggested to be a novel mark...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4027-0
更新日期：2018-05-01 00:00:00
abstract：:The level of the N terminal fragment of procollagen III (P3NP) levels of 100 consecutive patients affected by rheumatoid arthritis (RA) were evaluated in comparison with disease activity markers (erythrocytes sedimentation rate, C reactive protein), immunological status (rheumatoid factors, immune complexes) and joint...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02283106
更新日期：1992-12-01 00:00:00
abstract：:Hyperuricemia is not only a risk factor for gout but also an independent determinant of hypertension, diabetes, and chronic kidney diseases. Although the incidence of gout in Korean adults is increasing, epidemiologic studies on hyperuricemia in the general Korean population are limited. Thus, this study aimed at eval...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-018-4130-2
更新日期：2018-09-01 00:00:00
