Abstract：
OBJECTIVE:We aimed to evaluate the effect on renal functions and blood pressure of the addition of low dose aspirin (LDA) to cyclooxygenase-2 (COX-2) inhibitors or nonselective NSAIDs. METHODS:Two groups each containing 14 patients with one group using celecoxib and the other indomethacin regularly for at least 1 week were included into the study. Both groups were initially administered 100 mg/day (week 1), and later 300 mg/day (week 2) aspirin. Baseline and weekly serum creatinine, uric acid, electrolytes, creatinine clearance (CrCl) and blood pressure were obtained. RESULTS:Contrary to the celecoxib group, in the indomethacin group, both after the first and the second weeks the mean serum creatinine increased and CrCl decreased when compared to baseline values (p values<0.05). In the indomethacin group, when compared to baseline values systolic blood pressure was significantly higher after week 1 and uric acid level after week 2 (p values = 0.01). The frequency of patients with a >or=20% decrease in CrCl at the end of week 2 was higher in the indomethacin group than in the celecoxib group (42.9% vs. 0%, p = 0.016). The difference between the mean creatinine (p = 0.017) and CrCl values (p = 0.007) from baseline until after week 2 was more significant in the indomethacin group than in the celecoxib group. CONCLUSIONS:The addition of LDA to patients using indomethacin led to significant renal dysfunction. Subjects using celecoxib seem to have been protected from the renal side effects of LDA.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Pamuk ON,Cakir Ndoi
10.1007/s10067-005-1167-9subject
Has Abstractpub_date
2006-02-01 00:00:00pages
123-5issue
1eissn
0770-3198issn
1434-9949journal_volume
25pub_type
临床试验,信件abstract：:To demonstrate an as yet merely postulated generalized osteopathy in psoriatics, the serum calcium level, the alkaline phosphatase in the serum and the urinary excretion of hydroxyproline were evaluated in 24 patients with Ps and 24 patients with PA. Moreover, the bone bioptates from 25 patients with PA and 10 patient...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02208026
更新日期：1991-03-01 00:00:00
abstract：:In this scoping review, we sought to summarize the types of outcomes collected in pregnant patients with ankylosing spondylitis (AS), and to identify some methodological limitations related to pregnancy research in these patients. A comprehensive search was done to identify relevant articles in MEDLINE and Embase. We ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-021-05588-9
更新日期：2021-01-19 00:00:00
abstract：:Sarcoidosis is a multisystemic disease with cutaneous lesions present in about one fourth of patients. Cutaneous lesions may be specific or nonspecific based on the presence or the absence of sarcoidal granulomas. Subcutaneos sarcoidosis is the less frequent of the specific cutaneous lesions of sarcoidosis. We report ...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-011-1731-4
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:To explore the 18F-fluoro-dexoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging characteristics of adult-onset Still's disease (AOSD) and its significance in differential diagnosis from other connective tissue diseases (CTDs). METHODS:FDG PET/CT images of 54 patients with AOSD...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05041-3
更新日期：2020-09-01 00:00:00
abstract：:We encountered only three patients of carpal tunnel syndrome (CTS) due to tophaceous gout during 25 years of practice in a 'hand clinic' situated in a large metropolis in West India. In two patients, the CTS was bilateral, a rare occurrence in gout. There was an unwarranted delay (up to 9 years) in the diagnosis of bo...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0672-4
更新日期：2007-12-01 00:00:00
abstract：:The patient, a 44-year old woman with systemic lupus erythematosus, (SLE), developed infarction of the bowel and spleen after occlusion of the inferior mesenteric and splenic arteries, necessitating colectomy and splenectomy. She had had previous cerebral thromboses and a lower limb deep vein thrombosis. Histological ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02030977
更新日期：1986-01-01 00:00:00
abstract：:A 67-year-old woman, suffering from continuous hemoptysis, was admitted to our hospital where she was managed with mechanical ventilation. Computed tomography of the chest demonstrated bilateral massive alveolar hemorrhage without evidence of infectious disease. She was diagnosed with anti-myeloperoxidase antineutroph...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0355-6
更新日期：2007-07-01 00:00:00
abstract：:Systemic sclerosis (SSc) is an autoimmune disease which may lead to malnutrition. Previous studies have defined it with different criteria. No thorough evaluations of sarcopenia in SSc are available. The aim of the present study was to assess the prevalence and the potential association of malnutrition and sarcopenia ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3932-y
更新日期：2018-04-01 00:00:00
abstract：:This study aimed to investigate the effects of colchicine on growth parameters in familial Mediterranean fever (FMF) patients. Fifty-one (29 girls, 22 boys) FMF patients were enrolled in the study. All of the patients were in the prepubertal stage and had not received colchicine treatment before the study. Anthropomet...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-015-3077-9
更新日期：2016-06-01 00:00:00
abstract：:Belimumab is an effective and safe treatment option for systemic lupus erythematosus (SLE). However, data on treatment cessation are lacking. Thus, we investigated belimumab-free remission in SLE patients. SLE patients receiving belimumab in our institute (May 1, 2013-May 31, 2019) were retrospectively identified usin...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-020-05052-0
更新日期：2020-12-01 00:00:00
abstract：:This pilot study aimed to evaluate the correlation between clinical symptoms and cartilage volume through MRI in patients with knee osteoarthritis after 48 weeks of treatment with Structum®. Multicenter, double-blind, placebo-controlled, parallel-group study. Symptomatic knee osteoarthritis patients aged 50-75 years r...
journal_title：Clinical rheumatology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s10067-012-2022-4
更新日期：2012-09-01 00:00:00
abstract：:Idiopathic retroperitoneal fibrosis (IRPF) is a rare condition of unknown aetiology characterized by chronic non-specific inflammation of the retroperitoneum. The aim of this study is to describe, for the first time, the features of Spanish patients with IRPF. In this retrospective study, a clinical description was pe...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-013-2225-3
更新日期：2013-06-01 00:00:00
abstract：:Ochronotic spondyloarthropathy is a rare metabolic disease with the musculoskeletal manifestations of alkaptonuria. Ochronotic arthropathy patients may have spinal abnormalities similar to ankylosing spondylitis (AS). The proof of sacroiliac involvement or bamboo spine appearance is not sufficient either for diagnosis...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-005-0038-8
更新日期：2006-07-01 00:00:00
abstract：:The aim of the study was to determine the main demographic, epidemiological, clinical characteristics, and outcome in patients with various types of brucellar monoarticular involvement. Retrospectively, we analyzed medical histories of 331 patients with brucellar monoarticular involvement who were treated at the infec...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-016-3207-z
更新日期：2016-10-01 00:00:00
abstract：:The objective of this study was to understand the patient experience of musculoskeletal imaging tests for investigation of inflammatory arthritis and factors that contribute to this experience. We conducted a thematic analysis of semi-structured interviews with 33 patients who had a recent peripheral joint musculoskel...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-017-3760-0
更新日期：2018-08-01 00:00:00
abstract：:This study aimed to determine the frequency of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP) antibodies in a cohort of patients with palindromic rheumatism (PR) and to find determinants for progression to rheumatoid arthritis (RA). All new cases of PR (n=90) were included prospectively and followed up ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-014-2569-3
更新日期：2014-06-01 00:00:00
abstract：:Yao syndrome (YAOS), formerly named NOD2-associated autoinflammatory disease, is a periodic disease characterized by fever, dermatitis, polyarthritis, distal extremity swelling, and gastrointestinal and sicca-like symptoms associated with specific NOD2 sequence variants. All patients in the literature were Caucasians....
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-018-4274-0
更新日期：2018-12-01 00:00:00
abstract：:We report the case of a 45-year-old Caucasian woman suffering from ankylosing spondylitis and undifferentiated connective tissue disease in whom the prevailing clinical features were retinal vasculitis and inflammatory low back pain. HLA typing revealed the concomitant presence of B27 and DR2 antigens. We hypothesise ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF01451055
更新日期：1998-01-01 00:00:00
abstract：:Very recently, several studies have convincingly demonstrated the role of infection in the development of the antiphospholipid syndrome. Cross antibody-mediated reactivity due to molecular mimicry between endothelial glycoproteins and microbial products was considered as an important pathogenic mechanism. However, ano...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-006-0352-9
更新日期：2007-03-01 00:00:00
abstract：:As a class, tumor necrosis factor (TNF)-alpha inhibitors have provided clinicians significant control over chronic inflammatory diseases. With their widespread use has come the emergence of new side effects such as the reactivation of latent infections. One such infection that may reactivate is the hepatitis B virus (...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-010-1523-2
更新日期：2010-09-01 00:00:00
abstract：:A 62-year-old man who suffered from severe deforming arthritis, secondary to chronic tophaceous gout with multilobular, solid, tender, enlarged subcutaneous nodules, and draining tophi in right second finger, was treated by free flap and finally got the more functional and aesthetic result. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-009-1321-x
更新日期：2010-03-01 00:00:00
abstract：:Renal involvement in systemic lupus erythematosus (SLE) is common and has been associated with an increased risk of mortality [1]. Early diagnosis is imperative to control proteinuria and prevent the progression to end-stage renal disease. Standard induction therapies include cyclophosphamide (CYC) and mycophenolate m...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-016-3511-7
更新日期：2017-03-01 00:00:00
abstract：:A case of polymyositis associated with scleroderma, adult coeliac disease, diabetes mellitus and IgA nephropathy is reported in a 33-year-old male. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/BF02031278
更新日期：1984-12-01 00:00:00
abstract：:Mycoleptodiscus indicus is a recognized plant pathogen which has very rarely been reported as a cause of human infection. It is a tropical or subtropical fungus which is difficult to culture and identify from clinical specimens. This is the first report of septic arthritis with this fungus in a healthy Canadian male. ...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-010-1448-9
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVES:To evaluate sexual function in Tunisian women with rheumatoid arthritis (RA) and to compare it with that in voluntary healthy controls. METHODS:We conducted a cross-sectional study including 71 women with a confirmed diagnosis of RA according to the American College of Rheumatology/European League Against R...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-019-04726-8
更新日期：2019-12-01 00:00:00
abstract：:We encountered an adult patient with acute parvovirus B19 infection who presented with transient lupus-like symptoms (i.e., polyarthritis, fever, myalgia, pancytopenia, hypocomplementemia, and nephritis). Our case is characterized by the demonstration of acute nephritis as a complication of this infection, making it d...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-007-0691-1
更新日期：2008-01-01 00:00:00
abstract：:Polymyositis may occur along with other manifestations of chronic graft vs host disease after allogeneic bone marrow transplantation (BMT). Donor lymphocyte infusion (DLI) could produce durable remissions in relapsed patients with chronic myelogenous leukemia (CML) but it may contribute to the development of polymyosi...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-006-0346-7
更新日期：2007-07-01 00:00:00
abstract：:Initial treatment of trapeziometacarpal osteoarthritis (TMO) often consists of intra-articular injection of corticosteroids or hyaluronic acid. Several studies have shown that ultrasound (US)-guided injections demonstrate greater precision and effectiveness when compared to blind techniques. The aim of our study was t...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-011-1730-5
更新日期：2011-09-01 00:00:00
abstract：:Giant cell arteritis (GCA) is a granulomatous vasculitis involving large- and middle-sized arteries, with a predilection for cranial arteries. In this paper, we aim to describe a case of a biopsy- and ultrasound-proven GCA, presenting with anterior ischemic optic neuropathy (AION) and normal CRP and ESR at diagnosis a...
journal_title：Clinical rheumatology
pub_type： 杂志文章,评审
doi：10.1007/s10067-020-05116-1
更新日期：2020-10-01 00:00:00
abstract：:Erdheim-Chester disease (ECD) is a disseminated non-Langerhans' cell histiocytosis with multisystem involvement, including characteristic sclerotic musculoskeletal lesions. We present the case of a 27-year-old woman with a fulminant course and atypical involvement by ECD manifesting as extensive cerebrovascular diseas...
journal_title：Clinical rheumatology
pub_type： 杂志文章
doi：10.1007/s10067-003-0784-4
更新日期：2003-12-01 00:00:00
