From molecular mimicry to cross-reactivity or pathogen expansion? A hypothesis.

abstract：:The objective of this study was to analyze the clinical, laboratorial, and therapeutical response of polymyalgia rheumatica (PMR) to anti-tumor necrosis factor (anti-TNF) treatment. We systematically searched English articles on the subjects of PMR who were treated with TNF blockers in Pubmed from 1994 to 2010. In add...

journal_title：Clinical rheumatology

authors： Aikawa NE,Pereira RM,Lage L,Bonfá E,Carvalho JF

更新日期：2012-03-01 00:00:00

abstract：:Antiglomerular basement membrane antibody disease (aGD) remains a very uncommon entity in the pediatric population, characterized by pulmonary hemorrhage, glomerulonephritis, and antibodies against the glomerular basement membrane. We herein describe the case of a 14-year-old girl with primary pulmonary symptoms diagn...

journal_title：Clinical rheumatology

authors： Bayat A,Kamperis K,Herlin T

更新日期：2012-12-01 00:00:00

abstract：:MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression of targeted mRNAs, which are important in the pathogenesis of autoimmune diseases. MiRNAs may have the potential to serve as biomarkers of disease. We evaluated serum levels of selected miRNAs and their associations with disease activity in juvenile ...

journal_title：Clinical rheumatology

authors： Kamiya Y,Kawada J,Kawano Y,Torii Y,Kawabe S,Iwata N,Ito Y

更新日期：2015-10-01 00:00:00

abstract：:Evidence for Chagas disease reactivation (CDR) in rheumatologic patients under rheumatologic treatments (RTs) is scarce. To screen and follow-up patients with rheumatic diseases and concomitant Chagas disease under RT to detect CDR and to describe a possible relationship between CDR and specific RT. An observational, ...

journal_title：Clinical rheumatology

authors： Ringer A,Ruffino JP,Leiva R,Cuadranti N,Argento MC,Martínez MF,Rolla I,Chulibert S,Carbone D,Palatnik M,Cortese MN,Lagrutta M,Córdoba L,González FB,Pacini MF,Villar SR,Águila D,Bottasso OA,Pérez AR,Abdala M

更新日期：2021-01-12 00:00:00

abstract：:Circulating intercellular adhesion molecule-1 (ICAM-1) and 3 types of autoantibodies were measured in 30 patients with angiographical or pathological proved vasculitis. There were 18 patients with systemic vasculitis and 12 patients with cutaneous vasculitis. The measured antibodies included anti-endothelial cell anti...

journal_title：Clinical rheumatology

authors： Wang CR,Liu MF,Tsai RT,Chuang CY,Chen CY

更新日期：1993-09-01 00:00:00

abstract：INTRODUCTION:Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory benign breast disease. Although the etiology of this disease is unknown, it has been suggested that hormonal disorders, autoimmunity, smoking, and α1-antitrypsin deficiency may play a role in the etiopathogenesis. The aim is to investi...

journal_title：Clinical rheumatology

authors： Koksal H,Vatansev H,Artac H,Kadoglou N

更新日期：2020-05-01 00:00:00

abstract：:The objectives of the study were to assess sleep disturbances in systemic lupus erythematosus (SLE) and to compare these with a working sample and a treatment-seeking sample reporting insomnia. The primary sample was 172 people with SLE. This sample represented 32% of all members of two lupus support association. Two ...

journal_title：Clinical rheumatology

authors： Greenwood KM,Lederman L,Lindner HD

更新日期：2008-09-01 00:00:00

abstract：:Interferon regulatory factor 5 (IRF5) is a member of IRF family which induce signaling pathways and are involved in modulation of cell growth, differentiation, apoptosis, and immune system activity. Juvenile idiopathic arthritis (JIA) is an auto-inflammatory syndrome where the inflammatory markers are believed to play...

journal_title：Clinical rheumatology

authors： Esmaeili Reykande S,Rezaei A,Sadr M,Shabani M,Najmi Varzaneh F,Ziaee V,Rezaei N

更新日期：2018-10-01 00:00:00

abstract：:Belimumab is an effective and safe treatment option for systemic lupus erythematosus (SLE). However, data on treatment cessation are lacking. Thus, we investigated belimumab-free remission in SLE patients. SLE patients receiving belimumab in our institute (May 1, 2013-May 31, 2019) were retrospectively identified usin...

journal_title：Clinical rheumatology

authors： Nakai T,Fukui S,Ikeda Y,Shimizu H,Tamaki H,Okada M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Psoriatic arthritis (PsA) is an inflammatory disorder affecting the joints of psoriatic patients. Gelsolin regulated the actin assembly and disassembly. Reduction in plasma gelsolin levels was detected in tissue damages, including trauma, sepsis, and chronic inflammatory disorders. OBJECTIVES:The study aims...

journal_title：Clinical rheumatology

authors： Esawy MM,Makram WK,Albalat W,Shabana MA

更新日期：2020-06-01 00:00:00

abstract：:Pulse therapy is one of the most well-known methods used in the treatment of juvenile rheumatoid arthritis. This study assessed the outcome of methylprednisolone pulse therapy, its rate of efficacy, and its associated complications in patients with juvenile rheumatoid arthritis (JRA). This cross-sectional study was pe...

journal_title：Clinical rheumatology

authors： Aghighi Y,Attarod L,Javanmard M

更新日期：2008-11-01 00:00:00

abstract：:Articular involvement is described in a 58-year-old female patient with scleroderma. Radiological findings included intra-articular calcification, destructive osteoarthritis and selective involvement of the first metacarpal base. The discussion attempts to explain the way in which intra-articular calcification and ost...

journal_title：Clinical rheumatology

authors： Albert J,Ott H

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:This study was designed to compare outcomes of dose reduction, withdrawal, and continuation of tofacitinib in patients with rheumatoid arthritis (RA) and to examine effectiveness of rescue with an original treatment regimen for disease flare. METHODS:We prospectively enrolled 100 patients who had high or mod...

journal_title：Clinical rheumatology

authors： Mori S,Ueki Y

更新日期：2019-12-01 00:00:00

abstract：:In an open study, we have assessed the bone/soft tissue uptake index in recent osteoporotic vertebral collapse using scintigraphy. The evolution of these cases was followed-up at 6 months in 22 patients treated with 100 IU of salmon calcitonin plus 500 mg of elemental calcium/10 days per month and in 18 patients treat...

journal_title：Clinical rheumatology

authors： Rico H,Merono E,Del Olmo J,Revilla M

更新日期：1991-09-01 00:00:00

abstract：:A prospective, randomised, double-blind study was carried out to compare the respective efficacies of transforaminal and interspinous epidural corticosteroid injections in discal radiculalgia. Thirty-one patients (18 females, 13 males) with discal radicular pain of less than 3 months' duration were consecutively rando...

journal_title：Clinical rheumatology

authors： Thomas E,Cyteval C,Abiad L,Picot MC,Taourel P,Blotman F

更新日期：2003-10-01 00:00:00

abstract：:Socio-economic gradients in occurrence of diseases have been reported for many chronic conditions. However, whether the magnitude of socio-economic gradients differs across diseases and the extent to which lifestyle mediates such relationships are not known. Cross-sectional data from The National Monitor on Musculoske...

journal_title：Clinical rheumatology

authors： Putrik P,Ramiro S,Chorus AM,Keszei AP,Boonen A

更新日期：2018-12-01 00:00:00

abstract：:Iron-binding proteins (lactoferrin, transferrin and ferritin) and free iron were measured in synovial fluid (SF) from 30 patients with rheumatoid arthritis (RA) and 20 osteoarthritis (OA) patients. The iron-binding proteins except transferrin were significantly increased in RA SF as compared with OA SF. Similarly, fre...

journal_title：Clinical rheumatology

authors： Ahmadzadeh N,Shingu M,Nobunaga M

更新日期：1989-09-01 00:00:00

abstract：:This study aims to evaluate the impact of arthritis on the physical function of people living in a Maya-Yucateco rural community and to assess the association of known modifiable risk factors with the prevalence of overall arthritis and its main types (osteoarthritis and rheumatoid arthritis). Using a cross-sectional,...

journal_title：Clinical rheumatology

authors： Loyola-Sanchez A,Richardson J,Pelaez-Ballestas I,Alvarez-Nemegyei J,Lavis JN,Wilson MG,Wilkins S

更新日期：2016-07-01 00:00:00

abstract：:Up to now, there is no uniformly accepted treatment for avascular necrosis (AN) that alleviates pain and retards its progression. The aim of clinical and surgical treatments is usually only to improve blood support in the avascular area. The objective of the present study was to make a systematic review of the use of ...

journal_title：Clinical rheumatology

authors： Cardozo JB,Andrade DM,Santiago MB

更新日期：2008-06-01 00:00:00

abstract：:This paper is to assess the efficacy of different biologic DMARDs (bDMARDs) on several patient-reported outcomes (PROs) in randomized controlled trials (RCT) in axial spondyloarthritis (axSpA). A systematic literature review (SLR) was performed. MEDLINE (May 1, 2018) was used with the filters "published in the last 10...

journal_title：Clinical rheumatology

authors： Rodrigues-Manica S,Silva J,Cruz-Machado R,Coelho C,Duarte J,Vieira-Sousa E,Tavares-Costa J,Pimentel-Santos FM

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The association between pyoderma gangrenosum (PG) and rheumatoid arthritis (RA) was not investigated in the setting of controlled studies. The risk of PG among patients with RA is not established. OBJECTIVE:The study aims to evaluate the magnitude of the association between RA and the subsequent development...

journal_title：Clinical rheumatology

authors： Kridin K,Damiani G,Cohen AD

更新日期：2021-02-01 00:00:00

abstract：:A correlation study was performed on the degree of muscle weakness in 36 patients with dermatomyositis and 69 with polymyositis in relation to muscle biopsy findings, electromyography (EMG) abnormalities, and serum concentrations of creatine kinase (CK), aspartate aminotransferase (AST) and alanine aminotransferase (A...

journal_title：Clinical rheumatology

authors： Tymms KE,Beller EM,Webb J,Schrieber L,Buchanan WW

更新日期：1990-12-01 00:00:00

abstract：:Until recently, renal crisis was the most significant cause of morbidity and mortality in patients with scleroderma (SSc). Nowadays, following the introduction of angiotensin-converting enzyme inhibitors used in renovascular hypertension, pulmonary fibrosis and pulmonary hypertension have become the most common causes...

journal_title：Clinical rheumatology

authors： Davas EM,Peppas C,Maragou M,Alvanou E,Hondros D,Dantis PC

更新日期：1999-01-01 00:00:00

abstract：:Reactive arthritis (ReA) due to Gram-negative intestinal bacteria or Chlamydia, is associated by an unknown mechanism with HLA-B27. Like other MHC class I molecules, HLA-B27 presents antigenic peptides derived from intracellular proteins to CD8+ cytotoxic T cells (CTL). In humans however, CTL specific for ReA associat...

journal_title：Clinical rheumatology

authors： Ringrose JH,Yard BA,Verjans GM,Boog CJ

更新日期：1996-01-01 00:00:00

abstract：:Cytokine gene loci are one of the potential susceptibility factors in immuno-inflammatory diseases. Interleukin1 (IL-1) is a major monocyte derived proinflammatory cytokine that mediates tissue damage and cartilage loss in chronic arthritis. IL-1 locus has been linked to various autoimmune diseases, but data on juveni...

journal_title：Clinical rheumatology

authors： Aggarwal A,Srivastava R,Singh S,Kumar Dubey P

更新日期：2012-04-01 00:00:00

abstract：:The objective of this study was to determine the appropriate volume of saline to obtain a beneficial effect of arthroscopic lavage and the prognostic factors related to the clinical effect in a refractory rheumatoid knee. Arthroscopic lavage or arthrocentesis was performed in a random manner in 142 patients with relap...

journal_title：Clinical rheumatology

authors： Tanaka N,Sakahashi H,Hirose K,Ishima T,Ishii S

更新日期：2006-02-01 00:00:00

abstract：:Psoriatic arthritis (PsA) is a chronic T cell-mediated inflammatory spondyloarthropathy affecting 10-40 % of psoriasis (PSO) patients (0.3-1.0 % of the general population). Recent epidemiological studies have shown an increased prevalence of cardiovascular (CV) risk factors and/or morbidity among PSO or PsA patients a...

journal_title：Clinical rheumatology

authors： Khraishi M,Aslanov R,Rampakakis E,Pollock C,Sampalis JS

更新日期：2014-01-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is a rare disorder of unknown aetiology, characterised by high spiking fever, an evanescent, erythematous, maculopapular rash, arthralgia or arthritis, lymphadenopathy, hepatosplenomegaly, sore throat and serositis. It is associated with marked leukocytosis, high erythrocyte sediment...

journal_title：Clinical rheumatology

authors： Salaffi F,Filosa G,Bugatti L,Maestrini MD

更新日期：2000-01-01 00:00:00

abstract：:HLA B27 and other clinical findings were investigated in 18 Turkish patients with Reiter's syndrome (mean age 35.8 +/- 8.09). Male/female ratio was 2/1. All 18 patients were seronegative, 12 (66.6%) presenting with an asymmetrical oligoarticular arthritis. Radiological sacroiliitis and enthesopathy was found in 9 (50%...

journal_title：Clinical rheumatology

authors： Tuncer T,Arman MI,Akyokus A,Bütün B,Unal S

更新日期：1992-06-01 00:00:00

abstract：:Leptin is known to play an important role in the pathophysiology of osteoarthritis (OA). This study investigated whether synovial fluid (SF) leptin level is related to the radiographic severity of OA and its role as a quantitative marker for the detection of OA. SF was obtained from 42 OA patients who underwent knee s...

journal_title：Clinical rheumatology

authors： Ku JH,Lee CK,Joo BS,An BM,Choi SH,Wang TH,Cho HL

更新日期：2009-12-01 00:00:00